Kenneth J. Rhodes

ScholarGPS® ID: 44559857556596

Affiliation

Biogen, Cambridge, Massachusetts, U.S., United States

Affiliation History

Field

Life Sciences

Discipline

Neurosciences

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

6,042

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Addendum: The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease (journal article) Sevigny, Jeff \| Chiao, Ping \| Bussière, Thierry \| Weinreb, Paul H. \| Williams, Leslie \| Maier, Marcel \| Dunstan, Robert \| Salloway, Stephen \| Chen, Tianle \| Ling, Yan \| ... \| Sandrock, Alfred Nature, volume 546, issue 7659, pages 564-564 (2017). 10.1038/nature22809 Cited by (57) \| Cite \| Source \| Open Access
The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease (journal article) Sevigny, Jeff \| Chiao, Ping \| Bussière, Thierry \| Weinreb, Paul H. \| Williams, Leslie \| Maier, Marcel \| Dunstan, Robert \| Salloway, Stephen \| Chen, Tianle \| Ling, Yan \| ... \| Sandrock, Alfred Nature, volume 537, issue 7618, pages 50-56 (2016). 10.1038/nature19323 Cited by (2,116) \| Cite \| Source
P1‐033: Aducanumab Targets High Molecular Weight Soluble Aβ Oligomers and Restores Calcium to Normal Levels in TG2576 Mice (journal article) Kastanenka, Ksenia \| Bussière, Thierry \| Wang, Xueying \| Hou, Steven \| Arbel, Michal \| Takeda, Shuko \| Commins, Caitlin \| Qian, Fang \| Weinreb, Paul \| Rhodes, Kenneth \| Bacskai, Brian Alzheimer's & Dementia, volume 12, issue 7S_Part_8 (2016). 10.1016/j.jalz.2016.06.780 Cite \| Source
Pharmacodynamics of Dimethyl Fumarate Are Tissue Specific and Involve NRF2-Dependent and -Independent Mechanisms (journal article) Brennan, Melanie S. \| Patel, Hiral \| Allaire, Norm \| Thai, Alice \| Cullen, Patrick \| Ryan, Sarah \| Lukashev, Matvey \| Bista, Pradeep \| Huang, Ron \| Rhodes, Kenneth J. \| Scannevin, Robert H. Antioxidants & Redox Signaling, volume 24, issue 18, pages 1058-1071 (2016). 10.1089/ars.2015.6622 Cited by (47) \| Cite \| Source
BIIB042, a novel γ-secretase modulator, reduces amyloidogenic Aβ isoforms in primates and rodents and plaque pathology in a mouse model of Alzheimer's disease (journal article) Scannevin, Robert H. \| Chollate, Sowmya \| Brennan, Melanie S. \| Snodgrass-Belt, Pamela A. \| Peng, Hairuo \| Xu, Lin \| Jung, Mi-young \| Bussiere, Thierry \| Arastu, Mahin F. \| Talreja, Tina \| ... \| Rhodes, Kenneth J. Neuropharmacology, volume 103 (2016). 10.1016/j.neuropharm.2015.12.006 Cited by (12) \| Cite \| Source
Human-derived monoclonal antibodies for Alzheimer’s disease and related proteinopathies (journal article) Grimm, Jan \| Bussiere, Thierry \| Weinreb, Paul \| Maier, Marcel \| Dunstan, Robert \| Qian, Fang \| Arastu, Mahin \| Chollate, Sowmya \| Brennan, Melanie \| Quintero-Monzon, Omar \| ... \| Nitsch, Roger Neurobiology of Aging, volume 39 (2016). 10.1016/j.neurobiolaging.2016.01.111 Cite \| Source
Dimethyl Fumarate and Monoethyl Fumarate Exhibit Differential Effects on KEAP1, NRF2 Activation, and Glutathione Depletion In Vitro (journal article) Brennan, Melanie S. \| Matos, Maria F. \| Li, Bing \| Hronowski, Xiaoping \| Gao, Benbo \| Juhasz, Peter \| Rhodes, Kenneth J. \| Scannevin, Robert H. PLOS ONE, volume 10, issue 3, pages e0120254- (2015). 10.1371/journal.pone.0120254 Cited by (126) \| Cite \| Source \| Open Access
Neuroprotectants: Novel Approaches for Dementias (book chapter) In Encyclopedia of Psychopharmacology Rhodes, Kenneth J. Springer Berlin Heidelberg (2015) 10.1007/978-3-642-36172-2_401 Cite \| Source
Use of DR6 and p75 antagonists to promote survival of cells of the nervous system (patent) Mi, Sha \| Rhodes, Kenneth J. \| Pepinsky, R. Blake Patent Number: 8894999 (2014) Cited by (4) \| Cite \| Source
Methods of treatment using allosteric processing inhibitors for matrix metalloproteinases (patent) Leonard, Kristi A. \| Alexander, Richard Scott \| Barbay, Joseph Kent \| Bone, Roger F. \| Crysler, Carl \| Deckman, Ingrid Christa \| Jackson, Paul F. \| Kuo, Lawrence C. \| Lewandowski, Frank A. \| Maguire, Diane M. \| ... \| Wang, Aihua Patent Number: 8883473 (2014) Cited by (3) \| Cite \| Source
JNJ-40255293, a Novel Adenosine A2A /A1 Antagonist with Efficacy in Preclinical Models of Parkinson’s Disease (journal article) Atack, John R. \| Shook, Brian C. \| Rassnick, Stefanie \| Jackson, Paul F. \| Rhodes, Kenneth \| Drinkenburg, Wilhelmus H. \| Ahnaou, Abdallah \| te Riele, Paula \| Langlois, Xavier \| Hrupka, Brian \| ... \| Megens, Anton A. H. P. ACS Chemical Neuroscience, volume 5, issue 10, pages 1005-1019 (2014). 10.1021/cn5001606 Cited by (37) \| Cite \| Source
Methods for designing, selecting and/or optimizing allosteric processing inhibitors for matrix metalloproteinases (patent) Leonard, Kristi A. \| Alexander, Richard Scott \| Barbay, Joseph Kent \| Bone, Roger F. \| Deckman, Ingrid Christa \| Jackson, Paul F. \| Kuo, Lawrence C. \| Lewandowski, Frank A. \| Maguire, Diane M. \| Milligan, Cynthia M. \| ... \| Wang, Aihua Patent Number: 8798939 (2014) Cite \| Source
Crystal structure of the pro form of a matrix metalloproteinase and an allosteric processing inhibitor (patent) Leonard, Kristi A. \| Alexander, Richard Scott \| Barbay, Joseph Kent \| Bone, Roger F. \| Deckman, Ingrid Christa \| Jackson, Paul F. \| Kuo, Lawrence C. \| Lewandowski, Frank A. \| Maguire, Diane M. \| Milligan, Cynthia M. \| ... \| Wang, Aihua Patent Number: 8753857 (2014) Cited by (2) \| Cite \| Source
Dimethyl Fumarate and Monoethyl Fumarate Exhibit Differential Pharmacodynamic Effects and Pharmacokinetics In Vivo (P1.207) (journal article) Scannevin, Robert \| Szak, Suzanne \| King, Kristopher \| Brennan, Melanie \| Allaire, Normand \| Cullen, Patrick \| Thai, Alice \| Thomas, Ankur \| Gianni, Davide \| Chou, Alexander \| ... \| Rhodes, Kenneth Neurology, volume 82, issue 10_supplement (2014). 10.1212/WNL.82.10_supplement.P1.207 Cite \| Source
Dimethyl Fumarate and Monomethyl Fumarate are Distinguished by Non-Overlapping Pharmacodynamic Effects In Vivo (P1.206) (journal article) Brennan, Melanie \| Allaire, Normand \| Huss, David \| Cullen, Patrick \| Thai, Alice \| Szak, Suzanne \| Thomas, Ankur \| Gianni, Davide \| Carulli, John \| Fontenot, Jason \| ... \| Scannevin, Robert Neurology, volume 82, issue 10_supplement (2014). 10.1212/WNL.82.10_supplement.P1.206 Cited by (3) \| Cite \| Source
Dimethyl Fumarate and Monoethyl Fumarate Exhibit Differential Effects on Glutathione, Keap1 and Nrf2 Activation In Vitro (P1.204) (journal article) Scannevin, Robert \| Brennan, Melanie \| Matos, Maria \| Hronowski, Xiaoping \| Gao, Benbo \| Juhasz, Peter \| Rhodes, Kenneth Neurology, volume 82, issue 10_supplement (2014). 10.1212/WNL.82.10_supplement.P1.204 Cite \| Source
Synapto‐depressive effects of amyloid beta require PICK 1 (journal article) Alfonso, Stephanie \| Kessels, Helmut W. \| Banos, Charles C. \| Chan, Timothy R. \| Lin, Edward T. \| Kumaravel, Gnanasambandam \| Scannevin, Robert H. \| Rhodes, Kenneth J. \| Huganir, Richard \| Guckian, Kevin M. \| ... \| Malinow, Roberto European Journal of Neuroscience, volume 39, issue 7, pages 1225-1233 (2014). 10.1111/ejn.12499 Cited by (49) \| Cite \| Source \| Open Access
Neuroprotectants: Novel Approaches for Dementias (book chapter) In Encyclopedia of Psychopharmacology Rhodes, Kenneth J. Springer Berlin Heidelberg (2014) 10.1007/978-3-642-27772-6_401-2 Cite \| Source
Use of DR6 and p75 antagonists to promote survival of cells of the nervous system (patent) Rhodes, Kenneth J. \| Pepinsky, R. Blake \| Mi, Sha Patent Number: 8501178 (2013) Cited by (5) \| Cite \| Source
Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists (journal article) Shook, Brian C. \| Chakravarty, Devraj \| Barbay, J. Kent \| Wang, Aihua \| Leonard, Kristi \| Alford, Vernon \| Powell, Mark T. \| Rassnick, Stefanie \| Scannevin, Robert H. \| Carroll, Karen \| ... \| Jackson, Paul F. Bioorganic & Medicinal Chemistry Letters, volume 23, issue 9, pages 2688-2691 (2013). 10.1016/j.bmcl.2013.02.078 Cited by (19) \| Cite \| Source