Mandy Kwong

ScholarGPS® ID: 43246144354343

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Pharmacy and Pharmaceutical Sciences

Discipline

Pharmacology and Toxicology

Top Specialties

Immortalised Cell Line | Oxidative Stress

Metrics Summary

Publication Count

Predicted Citations

1,828

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Preclinical and translational pharmacology of afucosylated anti‐CCR8 antibody for depletion of tumour‐infiltrating regulatory T cells (journal article) Gampa, Gautham \| Spinosa, Phillip \| Getz, Jennifer \| Zhong, Yu \| Halpern, Wendy \| Esen, Emel \| Davies, John \| Chou, Cassie \| Kwong, Mandy \| Wang, Yingyun \| ... \| Hosseini, Iraj British Journal of Pharmacology, volume 181, issue 13, pages 2033-2052 (2024). 10.1111/bph.16326 Cite \| Source
A Minimal PBPK/PD Model with Expansion-Enhanced Target-Mediated Drug Disposition to Support a First-in-Human Clinical Study Design for a FLT3L-Fc Molecule (journal article) Hosseini, Iraj \| Fleisher, Brett \| Getz, Jennifer \| Decalf, Jérémie \| Kwong, Mandy \| Ovacik, Meric \| Bainbridge, Travis W. \| Moussion, Christine \| Rao, Gautham K. \| Gadkar, Kapil \| ... \| Ramanujan, Saroja Pharmaceutics, volume 16, issue 5, pages 660- (2024). 10.3390/pharmaceutics16050660 Cite \| Source
A Bispecific Modeling Framework Enables the Prediction of Efficacy, Toxicity, and Optimal Molecular Design of Bispecific Antibodies Targeting MerTK (journal article) Li, Ran \| Dere, Edward \| Kwong, Mandy \| Fei, Mingjian \| Dave, Rutwij \| Masih, Shabkhaiz \| Wang, Joy \| McNamara, Erin \| Huang, Haochu \| Liang, Wei-Ching \| ... \| Ovacik, Meric A. The AAPS Journal, volume 26, issue 1 (2024). 10.1208/s12248-023-00881-8 Cite \| Source
High-Throughput Analyses of Therapeutic Antibodies Using High-Field Asymmetric Waveform Ion Mobility Spectrometry Combined with SampleStream and Intact Protein Mass Spectrometry (journal article) Shi, Rachel Liuqing \| Dillon, Michael A. \| Compton, Philip D. \| Sawyer, William S. \| Thorup, John R. \| Kwong, Mandy \| Chan, Pamela \| Chiu, Cecilia P. C. \| Li, Ran \| Yadav, Rajbharan \| ... \| Tran, John C. Analytical Chemistry, volume 95, issue 47, pages 17263-17272 (2023). 10.1021/acs.analchem.3c03158 Cite \| Source
Retinal and Lens Degeneration in New Zealand White Rabbits Administered Intravitreal TSG-6 Link Domain-Rabbit FAb Fusion Proteins (journal article) Laing, Steven T. \| Tassew, Nardos \| Tesar, Devin \| Wang, Yue \| Crowell, Susan R. \| Gray, Julia \| Kwong, Mandy \| Loyet, Kelly M. \| Andaya, Roxanne \| Kusi, Aija \| Kelley, Robert F. Toxicologic Pathology, volume 49, issue 3, pages 634-646 (2021). 10.1177/0192623320969124 Cited by (2) \| Cite \| Source
Metabolic Response to NAD Depletion across Cell Lines Is Highly Variable (journal article) Xiao, Yang \| Kwong, Mandy \| Daemen, Anneleen \| Belvin, Marcia \| Liang, Xiaorong \| Hatzivassiliou, Georgia \| O’Brien, Thomas PLOS ONE, volume 11, issue 10, pages e0164166- (2016). 10.1371/journal.pone.0164166 Cited by (16) \| Cite \| Source \| Open Access
Metabolic Response to NAD Depletion across Cell Lines Is Highly Variable. (journal article) Xiao, Yang \| Kwong, Mandy \| Daemen, Anneleen \| Belvin, Marcia \| Liang, Xiaorong \| Hatzivassiliou, Georgia \| O'Brien, Thomas PloS one, volume 11, issue 10 (2016). Cite
Structural basis of the broadly neutralizing anti‐interferon‐α antibody rontalizumab (journal article) Maurer, Brigitte \| Bosanac, Ivan \| Shia, Steven \| Kwong, Mandy \| Corpuz, Racquel \| Vandlen, Richard \| Schmidt, Kerstin \| Eigenbrot, Charles Protein Science, volume 24, issue 9, pages 1440-1450 (2015). 10.1002/pro.2729 Cited by (11) \| Cite \| Source \| Open Access
Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors (journal article) Wang, Weiru \| Elkins, Kristi \| Oh, Angela \| Ho, Yen-Ching \| Wu, Jiansheng \| Li, Hong \| Xiao, Yang \| Kwong, Mandy \| Coons, Mary \| Brillantes, Bobby \| ... \| Belmont, Lisa D. PLoS ONE, volume 9, issue 10, pages e109366- (2014). 10.1371/journal.pone.0109366 Cited by (30) \| Cite \| Source \| Open Access
Hominoid-specific enzyme GLUD2 promotes growth of IDH1 R132H glioma (journal article) Chen, Ruihuan \| Nishimura, Merry C. \| Kharbanda, Samir \| Peale, Frank \| Deng, Yuzhong \| Daemen, Anneleen \| Forrest, William F. \| Kwong, Mandy \| Hedehus, Maj \| Hatzivassiliou, Georgia \| ... \| Phillips, Heidi S. Proceedings of the National Academy of Sciences, volume 111, issue 39, pages 14217-14222 (2014). 10.1073/pnas.1409653111 Cited by (88) \| Cite \| Source \| Open Access
Dependence of Tumor Cell Lines and Patient-Derived Tumors on the NAD Salvage Pathway Renders Them Sensitive to NAMPT Inhibition with GNE-618 (journal article) Xiao, Yang \| Elkins, Kristi \| Durieux, Jenni K \| Lee, Leslie \| Oeh, Jason \| Yang, Lulu X \| Liang, Xiaorong \| DelNagro, Chris \| Tremayne, Jarrod \| Kwong, Mandy \| ... \| O'Brien, Thomas Neoplasia, volume 15, issue 10, pages 1151-IN23 (2013). 10.1593/neo.131304 Cited by (67) \| Cite \| Source \| Open Access
An ARL3–UNC119–RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium (journal article) Wright, Kevin J. \| Baye, Lisa M. \| Olivier-Mason, Anique \| Mukhopadhyay, Saikat \| Sang, Liyun \| Kwong, Mandy \| Wang, Weiru \| Pretorius, Pamela R. \| Sheffield, Val C. \| Sengupta, Piali \| ... \| Jackson, Peter K. Genes & Development, volume 25, issue 22, pages 2347-2360 (2011). 10.1101/gad.173443.111 Cited by (184) \| Cite \| Source \| Open Access
Cutting Edge: Novel Human Dendritic Cell- and Monocyte-Attracting Chemokine-Like Protein Identified by Fold Recognition Methods (journal article) Pisabarro, M. Teresa \| Leung, Beatrice \| Kwong, Mandy \| Corpuz, Racquel \| Frantz, Gretchen D. \| Chiang, Nancy \| Vandlen, Richard \| Diehl, Lauri J. \| Skelton, Nicholas \| Kim, Hok Seon \| ... \| Schmidt, Kerstin N. The Journal of Immunology, volume 176, issue 4, pages 2069-2073 (2006). 10.4049/jimmunol.176.4.2069 Cited by (77) \| Cite \| Source \| Open Access
APC-Independent Activation of NK Cells by the Toll-Like Receptor 3 Agonist Double-Stranded RNA (journal article) Schmidt, Kerstin N. \| Leung, Beatrice \| Kwong, Mandy \| Zarember, Kol A. \| Satyal, Sanjeev \| Navas, Tony A. \| Wang, Fay \| Godowski, Paul J. The Journal of Immunology, volume 172, issue 1, pages 138-143 (2004). 10.4049/jimmunol.172.1.138 Cited by (209) \| Cite \| Source \| Open Access
Deficiency of the Nrf1 and Nrf2 Transcription Factors Results in Early Embryonic Lethality and Severe Oxidative Stress (journal article) Leung, Laura \| Kwong, Mandy \| Hou, Stephen \| Lee, Candy \| Chan, Jefferson Y. Journal of Biological Chemistry, volume 278, issue 48, pages 48021-48029 (2003). 10.1074/jbc.M308439200 Cited by (257) \| Cite \| Source \| Open Access
Nrf1 Is Critical for Redox Balance and Survival of Liver Cells during Development (journal article) Chen, Linyun \| Kwong, Mandy \| Lu, Ronghua \| Ginzinger, David \| Lee, Candy \| Leung, Laura \| Chan, Jefferson Y. Molecular and Cellular Biology, volume 23, issue 13, pages 4673-4686 (2003). 10.1128/MCB.23.13.4673-4686.2003 Cited by (124) \| Cite \| Source \| Open Access
Reduced oxidative-stress response in red blood cells from p45NFE2-deficient mice (journal article) Chan, Jefferson Y. \| Kwong, Mandy \| Lo, Margaret \| Emerson, Renee \| Kuypers, Frans A. Blood, volume 97, issue 7, pages 2151-2158 (2001). 10.1182/blood.V97.7.2151 Cited by (46) \| Cite \| Source \| Open Access
The CNC Basic Leucine Zipper Factor, Nrf1, Is Essential for Cell Survival in Response to Oxidative Stress-inducing Agents (journal article) Kwong, Mandy \| Kan, Yuet Wai \| Chan, Jefferson Y. Journal of Biological Chemistry, volume 274, issue 52, pages 37491-37498 (1999). 10.1074/jbc.274.52.37491 Cited by (155) \| Cite \| Source \| Open Access