Alyssa L. Gagne

ScholarGPS® ID: 43228969625197

Affiliation

Children's Hospital of Philadelphia

Affiliation History

Field

Medicine

Discipline

Pathology

Top Specialties

Stem Cell | Induced Pluripotent Stem Cell | Immortalised Cell Line | Leukemia

Metrics Summary

Publication Count

Predicted Citations

456

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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KOLF2.1J iPSCs carry CNVs associated with neurodevelopmental disorders (journal article) Gracia-Diaz, Carolina \| Perdomo, Jonathan E. \| Khan, Munir E. \| Roule, Thomas \| Disanza, Brianna L. \| Cajka, Gregory G. \| Lei, Sunyimeng \| Gagne, Alyssa L. \| Maguire, Jean Ann \| Shalem, Ophir \| ... \| Akizu, Naiara Cell Stem Cell, volume 31, issue 3, pages 288-289 (2024). 10.1016/j.stem.2024.02.007 Cite \| Source
Megakaryocyte-induced contraction of plasma clots: cellular mechanisms and structural mechanobiology (journal article) Kim, Oleg V. \| Litvinov, Rustem I. \| Gagne, Alyssa L. \| French, Deborah L. \| Brass, Lawrence F. \| Weisel, John W. Blood, volume 143, issue 6, pages 548-560 (2024). 10.1182/blood.2023021545 Cited by (3) \| Cite \| Source
Generation and characterization of multiple sulfatase deficiency iPSC-line and neurogenin-2-induced neurons (journal article) Finoti, Livia Sertori \| Pham, Vi \| Cassidy, Margaret \| Gagne, Alyssa \| Waxman, Elisa A. \| Ahrens-Nicklas, Rebecca Molecular Genetics and Metabolism, volume 141, issue 2, pages 108040- (2024). 10.1016/j.ymgme.2023.108040 Cite \| Source
Generation of three induced pluripotent stem cell lines from individuals with Aicardi-Goutières syndrome caused by a c.3019G>A (p.G1007R) autosomal dominant pathogenic variant in ADAR1 (journal article) Garcia, Luis \| Gonzalez, Carlos Dominguez \| Gagne, Alyssa \| McGuire, Jean Ann \| French, Deborah \| Takanohashi, Asako \| Almad, Akshata \| Vanderver, Adeline \| Sase, Sunetra Stem Cell Research, volume 74 (2024). 10.1016/j.scr.2023.103299 Cite \| Source
A novel iPSC model reveals selective vulnerability of neurons in multiple sulfatase deficiency (journal article) Pham, Vi \| Sertori Finoti, Livia \| Cassidy, Margaret M. \| Maguire, Jean Ann \| Gagne, Alyssa L. \| Waxman, Elisa A. \| French, Deborah L. \| King, Kaitlyn \| Zhou, Zitao \| Gelb, Michael H. \| ... \| Ahrens-Nicklas, Rebecca C. Molecular Genetics and Metabolism, volume 141, issue 2, pages 108116- (2024). 10.1016/j.ymgme.2023.108116 Cite \| Source
Reproducible Differentiation of Human Pluripotent Stem Cells into Two‐Dimensional Cortical Neuron Cultures with Checkpoints for Success (journal article) Waxman, Elisa A. \| Dungan, Lea V. \| DeFlitch, Leah M. \| Merchant, Julie P. \| Gagne, Alyssa L. \| Goldberg, Ethan M. \| French, Deborah L. Current Protocols, volume 3, issue 12 (2023). 10.1002/cpz1.948 Cited by (1) \| Cite \| Source
Single-Cell Transcriptomics Reveal Altered Hematopoietic Mechanisms Driven By T21 and GATA1s (journal article) Takasaki, Kaoru \| Thom, Christopher S. \| Smith, David \| Kumar, Sara S. \| Sit, Ying Ting \| Gagne, Alyssa \| French, Deborah L. \| Chou, Stella T. Blood, volume 142, issue Supplement 1, pages 2685-2685 (2023). 10.1182/blood-2023-185278 Cite \| Source
Generation of CHOPi-008-B, a euploid iPSC line from a patient with Trisomy 21 and a GATA1 mutation (journal article) Takasaki, Kaoru \| Kumar, Sara S. \| Gagne, Alyssa \| French, Deborah L. \| Chou, Stella T. Stem Cell Research, volume 72 (2023). 10.1016/j.scr.2023.103198 Cite \| Source
Generation of CHOPi012-A iPSC line from a patient with visceral myopathy-related chronic intestinal pseudo-obstruction (journal article) Hashmi, Sohaib K. \| Schneider, Sabine \| Gagne, Alyssa L. \| Maguire, Jean Ann \| Gadue, Paul \| Heuckeroth, Robert O. \| French, Deborah L. Stem Cell Research, volume 71 (2023). 10.1016/j.scr.2023.103176 Cite \| Source
Generation of CHOPe003-A ESC line to study an ACTG2 variant affecting smooth muscle development and function (journal article) Hashmi, Sohaib K. \| Schneider, Sabine \| Gagne, Alyssa L. \| Maguire, Jean Ann \| Anderson, Sierra \| Gadue, Paul \| Heuckeroth, Robert O. \| French, Deborah L. Stem Cell Research, volume 71 (2023). 10.1016/j.scr.2023.103186 Cite \| Source
Generation of a human Tropomyosin 1 knockout iPSC line (journal article) Wilken, Madison B. \| Maguire, Jean Ann \| Dungan, Lea V. \| Gagne, Alyssa \| Osorio-Quintero, Catherine \| Waxman, Elisa A \| Chou, Stella T. \| Gadue, Paul \| French, Deborah L. \| Thom, Christopher S. Stem Cell Research, volume 71 (2023). 10.1016/j.scr.2023.103161 Cite \| Source
Generation of 2 isogenic clones from a patient with Trisomy 21 and a GATA1 mutation (journal article) Takasaki, Kaoru \| Kumar, Sara S. \| Gagne, Alyssa \| French, Deborah L. \| Chou, Stella T. Stem Cell Research, volume 69 (2023). 10.1016/j.scr.2023.103098 Cited by (3) \| Cite \| Source
Generation of three induced Pluripotent Stem Cell lines from individuals with Hypomyelination with Atrophy of Basal Ganglia and Cerebellum caused by a c.745G>A (p.D249N) autosomal dominant mutation in TUBB4A (journal article) Almad, Akshata A \| Garcia, Luis \| Takanohashi, Asako \| Gagne, Alyssa \| Yang, Wenli \| Ann McGuire, Jean \| French, Deborah \| Vanderver, Adeline Stem Cell Research, volume 69 (2023). 10.1016/j.scr.2023.103083 Cited by (1) \| Cite \| Source
Mapping PTBP2 binding in human brain identifies SYNGAP1 as a target for therapeutic splice switching (journal article) Dawicki-McKenna, Jennine M. \| Felix, Alex J. \| Waxman, Elisa A. \| Cheng, Congsheng \| Amado, Defne A. \| Ranum, Paul T. \| Bogush, Alexey \| Dungan, Lea V. \| Maguire, Jean Ann \| Gagne, Alyssa L. \| ... \| Prosser, Benjamin L. Nature Communications, volume 14, issue 1 (2023). 10.1038/s41467-023-38273-3 Cited by (7) \| Cite \| Source
Screening of approved drugs identifies 3 generation retinoids as therapeutic agents in multiple sulfatase deficiency (journal article) Schlotawa, Lars \| Kettwig, Matthias \| Ahrens-Nicklas, Rebecca \| Baud, Matthias \| Brunetti-Pierri, Nicola \| Gagne, Alyssa \| Schroeder, Sophie \| Monfregula, Jilenia \| Pena, Tonatiuh \| Radhakrishnan, Karthikeyan \| ... \| Gaertner, Jutta Molecular Genetics and Metabolism, volume 138, issue 2, pages 107308- (2023). 10.1016/j.ymgme.2022.107308 Cite \| Source
Intersection of GATA1 and DYRK1A in Trisomy 21 Leukemogenesis (journal article) Sit, Ying Ting \| An, Hyun Hyung \| Gagne, Alyssa \| French, Deborah L \| Chou, Stella T. Blood, volume 140, issue Supplement 1, pages 5842-5843 (2022). 10.1182/blood-2022-169399 Cite \| Source
The use of pluripotent stem cells to generate diagnostic tools for transfusion medicine (journal article) An, Hyun Hyung \| Gagne, Alyssa L. \| Maguire, Jean Ann \| Pavani, Giulia \| Abdulmalik, Osheiza \| Gadue, Paul \| French, Deborah L. \| Westhoff, Connie M. \| Chou, Stella T. Blood, volume 140, issue 15, pages 1723-1734 (2022). 10.1182/blood.2022015883 Cited by (7) \| Cite \| Source
Derivation and investigation of the first human cell-based model of Beckwith-Wiedemann syndrome (journal article) Chang, Suhee \| Hur, Stella K. \| Naveh, Natali S. Sobel \| Thorvaldsen, Joanne L. \| French, Deborah L. \| Gagne, Alyssa L \| Jobaliya, Chintan D. \| Anguera, Montserrat C. \| Bartolomei, Marisa S. \| Kalish, Jennifer M Epigenetics, volume 16, issue 12, pages 1295-1305 (2021). 10.1080/15592294.2020.1861172 Cited by (3) \| Cite \| Source
Detection of Rh Antibodies in Patient Plasma Using Genome Engineered Induced Pluripotent Stem Cell-Derived Red Cells (journal article) An, Hyun Hyung \| Maguire, Jean Ann \| Gagne, Alyssa \| Gadue, Paul \| French, Deborah L \| Westhoff, Connie M. \| Chou, Stella T. Blood, volume 138, issue Supplement 1, pages 350-350 (2021). 10.1182/blood-2021-151202 Cite \| Source
Generation of a double insulin and somatostatin reporter line, SCSe001-A-3, for the advancement of stem cell-derived pancreatic islets (journal article) Leavens, Karla F. \| Liao, Chia-min \| Gagne, Alyssa L. \| Kishore, Siddharth \| Cardenas-Diaz, Fabian L. \| French, Deborah L. \| Gadue, Paul Stem Cell Research, volume 50 (2021). 10.1016/j.scr.2020.102112 Cited by (6) \| Cite \| Source