Shang-Fan Yu

ScholarGPS® ID: 42362740249373

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Medicine

Discipline

Oncology

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

3,787

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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T cell–Dependent Bispecific Therapy Enhances Innate Immune Activation and Antibody-Mediated Killing (journal article) Besla, Rickvinder \| Penuel, Elicia \| Del Rosario, Geoff \| Cosino, Ely \| Myrta, Szymon \| Dillon, Mike \| Lazar, Greg A. \| Nickles, Dorothee \| Spiess, Christoph \| Yu, Shang-Fan \| Polson, Andrew G. Cancer Immunology Research, volume 12, issue 1, pages 60-71 (2024). 10.1158/2326-6066.CIR-23-0072 Cited by (1) \| Cite \| Source
Development of T-cell engagers selective for cells co-expressing two antigens (journal article) Dicara, Danielle M. \| Bhakta, Sunil \| Go, Mary Ann \| Ziai, James \| Firestein, Ron \| Forrest, Bill \| Gu, Chen \| Leong, Steven R. \| Lee, Genee \| Yu, Shang-Fan \| ... \| Agard, Nicholas J. mAbs, volume 14, issue 1 (2022). 10.1080/19420862.2022.2115213 Cited by (8) \| Cite \| Source
Determining the conditions for robust acidoCEST MRI to measure extracellular pH in tumors in vivo (conference) Virgincar, Rohan \| Barck, Kai \| Go, Mary Ann \| Rosario, Geoffrey Del \| Yu, Shang-Fan \| Choy, ManKin \| Gogineni, Alvin \| Elstrott, Justin \| Gill, Herman \| Marik, Jan \| ... \| Xie, Luke Joint Annual Meeting ISMRM-ESMRMB ISMRT 31st Annual Meeting (2022) London, England, UK 10.58530/2022/4451 Cite \| Source
Valency of HER2 Targeting Antibodies Influences Tumor Cell Internalization and Penetration (journal article) Ramos, Madeleine K. \| Mandikian, Danielle \| Sermeño, Lauren N. \| King, Anna \| Dent, Alecia T. \| Ho, Jason \| Ulufatu, Sheila \| Lombana, T. Noelle \| Spiess, Christoph \| Go, Mary Ann T. \| ... \| Boswell, C. Andrew Molecular Cancer Therapeutics, volume 20, issue 10, pages 1956-1965 (2021). 10.1158/1535-7163.MCT-20-1097 Cited by (2) \| Cite \| Source
Calicheamicin Antibody–Drug Conjugates with Improved Properties (journal article) Vollmar, Breanna S. \| Frantz, Chris \| Schutten, Melissa M. \| Zhong, Fiona \| del Rosario, Geoffrey \| Go, Mary Ann T. \| Yu, Shang-Fan \| Leipold, Douglas D. \| Kamath, Amrita V. \| Ng, Carl \| ... \| Pillow, Thomas H. Molecular Cancer Therapeutics, volume 20, issue 6, pages 1112-1120 (2021). 10.1158/1535-7163.MCT-20-0035 Cited by (17) \| Cite \| Source
An Anti–CD22- seco -CBI-Dimer Antibody–Drug Conjugate (ADC) for the Treatment of Non-Hodgkin Lymphoma That Provides a Longer Duration of Response than Auristatin-Based ADCs in Preclinical Models (journal article) Yu, Shang-Fan \| Lee, Donna W. \| Zheng, Bing \| del Rosario, Geoffrey \| Leipold, Douglas \| Booler, Helen \| Zhong, Fiona \| Carrasco-Triguero, Montserrat \| Hong, Kyu \| Yan, Peter \| ... \| Polson, Andrew G. Molecular Cancer Therapeutics, volume 20, issue 2, pages 340-346 (2021). 10.1158/1535-7163.MCT-20-0046 Cited by (9) \| Cite \| Source
Systematic Variation of Pyrrolobenzodiazepine (PBD)-Dimer Payload Physicochemical Properties Impacts Efficacy and Tolerability of the Corresponding Antibody–Drug Conjugates (journal article) Staben, Leanna R. \| Chen, Jinhua \| Cruz-Chuh, Josefa dela \| del Rosario, Geoff \| Go, Mary Ann \| Guo, Jun \| Khojasteh, S. Cyrus \| Kozak, Katherine R. \| Li, Guangmin \| Ng, Carl \| ... \| Dragovich, Peter S. Journal of Medicinal Chemistry, volume 63, issue 17, pages 9603-9622 (2020). 10.1021/acs.jmedchem.0c00691 Cited by (13) \| Cite \| Source
Effect of Modulating FcRn Binding on Direct and Pretargeted Tumor Uptake of Full-length Antibodies (journal article) Nazarova, Lidia \| Rafidi, Hanine \| Mandikian, Danielle \| Ferl, Gregory Z. \| Koerber, James T. \| Davies, Christopher W. \| Ulufatu, Sheila \| Ho, Jason \| Lau, Jeffrey \| Yu, Shang-Fan \| ... \| Boswell, C. Andrew Molecular Cancer Therapeutics, volume 19, issue 4, pages 1052-1058 (2020). 10.1158/1535-7163.MCT-19-1015 Cited by (6) \| Cite \| Source
Anti-CD33 antibodies and immunoconjugates (patent) Yu, Shang-Fan \| Liang, Wei-Ching \| Wu, Yan \| Leong, Steven \| Polson, Andrew Patent Number: 10556951 (2020) Cite \| Source
Improved translation of stability for conjugated antibodies using an in vitro whole blood assay (journal article) Fourie-O’Donohue, Aimee \| Chu, Phillip Y. \| dela Cruz Chuh, Josefa \| Tchelepi, Robert \| Tsai, Siao Ping \| Tran, John C. \| Sawyer, William S. \| Su, Dian \| Ng, Carl \| Xu, Keyang \| ... \| Kozak, Katherine R. mAbs, volume 12, issue 1 (2020). 10.1080/19420862.2020.1715705 Cited by (11) \| Cite \| Source
Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer (journal article) Boswell, C. Andrew \| Yadav, Daniela Bumbaca \| Mundo, Eduardo E. \| Yu, Shang-Fan \| Lacap, Jennifer Arca \| Fourie-O’Donohue, Aimee \| Kozak, Katherine R. \| Ferl, Gregory Z. \| Zhang, Crystal \| Ho, Jason \| ... \| Lin, Kedan Oncotarget, volume 10, issue 58, pages 6234-6244 (2019). 10.18632/oncotarget.27263 Cited by (13) \| Cite \| Source
Exposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to Tissues (journal article) Zhang, Donglu \| Dragovich, Peter S. \| Yu, Shang-Fan \| Ma, Yong \| Pillow, Thomas H. \| Sadowsky, Jack D. \| Su, Dian \| Wang, Wei \| Polson, Andrew \| Khojasteh, S. Cyrus \| Hop, Cornelis E.C.A. Drug Metabolism and Disposition, volume 47, issue 10, pages 1146-1155 (2019). 10.1124/dmd.119.087023 Cited by (24) \| Cite \| Source
An Anti–CLL-1 Antibody–Drug Conjugate for the Treatment of Acute Myeloid Leukemia (journal article) Zheng, Bing \| Yu, Shang-Fan \| del Rosario, Geoffrey \| Leong, Steven R. \| Lee, Genee Y. \| Vij, Rajesh \| Chiu, Cecilia \| Liang, Wei-Ching \| Wu, Yan \| Chalouni, Cecile \| ... \| Polson, Andrew G. Clinical Cancer Research, volume 25, issue 4, pages 1358-1368 (2019). 10.1158/1078-0432.CCR-18-0333 Cited by (48) \| Cite \| Source
Biotransformation of ADCs. Pathways and enzymes (journal article) Zhang, Donglu \| Pillow, Thomas H. \| Su, Dian \| Caculitan, Niña G. \| Chuh, Joseha \| Ma, Yong \| Yu, Shang-Fan \| Yu, Shuai Drug Metabolism and Pharmacokinetics, volume 34, issue 1, pages S13- (2019). 10.1016/j.dmpk.2018.09.065 Cite \| Source
Intra-tissue catabolite characterization is a missing link in discovery of ADCs (journal article) Zhang, Donglu \| Ma, Yong \| Yu, Shang-Fan \| Pillow, Thomas H. \| Sadowsky, Jack D. \| Su, Dian \| Polson, Andrew G. \| Dragovich, Peter S. \| Hop, Cornelis ECA. \| Khojasteh, S. Cyrus Drug Metabolism and Pharmacokinetics, volume 34, issue 1, pages S9- (2019). 10.1016/j.dmpk.2018.09.043 Cite \| Source
Site-specific conjugation allows modulation of click reaction stoichiometry for pretargeted SPECT imaging (journal article) Mandikian, Danielle \| Rafidi, Hanine \| Adhikari, Pragya \| Venkatraman, Priya \| Nazarova, Lidia \| Fung, Gabriel \| Figueroa, Isabel \| Ferl, Gregory Z. \| Ulufatu, Sheila \| Ho, Jason \| ... \| Boswell, C. Andrew mAbs, volume 10, issue 8, pages 1269-1280 (2018). 10.1080/19420862.2018.1521132 Cited by (8) \| Cite \| Source
FRET Reagent Reveals the Intracellular Processing of Peptide-Linked Antibody–Drug Conjugates (journal article) Lee, Byoung-Chul \| Chalouni, Cecile \| Doll, Sophia \| Nalle, Sam C. \| Darwish, Martine \| Tsai, Siao Ping \| Kozak, Katherine R. \| Del-Rosario, Geoffrey \| Yu, Shang-Fan \| Erickson, Hans \| Vandlen, Richard Bioconjugate Chemistry, volume 29, issue 7, pages 2468-2477 (2018). 10.1021/acs.bioconjchem.8b00362 Cited by (26) \| Cite \| Source
Antibodies and immunoconjugates (patent) Polakis, Paul \| Dragovich, Peter \| Pillow, Thomas Harden \| Yu, Shang-Fan Patent Number: 10017577 (2018) Cited by (1) \| Cite \| Source
Characterization of in vivo biotransformations for trastuzumab emtansine by high-resolution accurate-mass mass spectrometry (journal article) He, Jintang \| Yu, Shang-Fan \| Yee, Sharon \| Kaur, Surinder \| Xu, Keyang mAbs (2018). 10.1080/19420862.2018.1494487 Cited by (12) \| Cite \| Source
Anti-CD33 antibodies and immunoconjugates (patent) Yu, Shang-Fan \| Liang, Wei-Ching \| Wu, Yan \| Leong, Steven \| Polson, Andrew Patent Number: 9951133 (2018) Cited by (1) \| Cite \| Source