Taraneh Mirzadegan

ScholarGPS® ID: 40184130142442

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Medicine

Discipline

Immunology

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

4,447

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Novel Reagent Space: Identifying Unorderable but Readily Synthesizable Building Blocks (journal article) Seierstad, Mark \| Tichenor, Mark S. \| DesJarlais, Renee L. \| Na, Jim \| Bacani, Genesis M. \| Chung, De Michael \| Mercado-Marin, Eduardo V. \| Steffens, Helena C. \| Mirzadegan, Taraneh ACS Medicinal Chemistry Letters, volume 12, issue 11, pages 1853-1860 (2021). 10.1021/acsmedchemlett.1c00340 Cited by (6) \| Cite \| Source
Impact of Protein Preparation on Resulting Accuracy of FEP Calculations (journal article) Shih, Amy Y. \| Hack, Michael \| Mirzadegan, Taraneh Journal of Chemical Information and Modeling, volume 60, issue 11, pages 5287-5289 (2020). 10.1021/acs.jcim.0c00445 Cited by (12) \| Cite \| Source
Breaking the Glass Ceiling in Simulation and Modeling: Women in Pharmaceutical Discovery (journal article) Damm-Ganamet, Kelly L. \| DesJarlais, Renee L. \| Marrone, Tami \| Shih, Amy Y. \| Schiffer, Jamie M. \| Perez-Benito, Laura \| Mirzadegan, Taraneh Journal of Medicinal Chemistry, volume 63, issue 5, pages 1929-1936 (2020). 10.1021/acs.jmedchem.9b01512 Cited by (4) \| Cite \| Source
A computational approach yields selective inhibitors of human excitatory amino acid transporter 2 (EAAT2) (journal article) Damm-Ganamet, Kelly L. \| Rives, Marie-Laure \| Wickenden, Alan D. \| McAllister, Heather M. \| Mirzadegan, Taraneh Journal of Biological Chemistry, volume 295, issue 13, pages 4359-4366 (2020). 10.1074/jbc.AC119.011190 Cited by (1) \| Cite \| Source
D3R grand challenge 4: blind prediction of protein–ligand poses, affinity rankings, and relative binding free energies (journal article) Parks, Conor D. \| Gaieb, Zied \| Chiu, Michael \| Yang, Huanwang \| Shao, Chenghua \| Walters, W. Patrick \| Jansen, Johanna M. \| McGaughey, Georgia \| Lewis, Richard A. \| Bembenek, Scott D. \| ... \| Gilson, Michael K. Journal of Computer-Aided Molecular Design, volume 34, issue 2, pages 99-119 (2020). 10.1007/s10822-020-00289-y Cited by (73) \| Cite \| Source
Accelerating Lead Identification by High Throughput Virtual Screening: Prospective Case Studies from the Pharmaceutical Industry (journal article) Damm-Ganamet, Kelly L. \| Arora, Nidhi \| Becart, Stephane \| Edwards, James P. \| Lebsack, Alec D. \| McAllister, Heather M. \| Nelen, Marina I. \| Rao, Navin L. \| Westover, Lori \| Wiener, John J. M. \| Mirzadegan, Taraneh Journal of Chemical Information and Modeling, volume 59, issue 5, pages 2046-2062 (2019). 10.1021/acs.jcim.8b00941 Cited by (23) \| Cite \| Source
D3R Grand Challenge 3: blind prediction of protein–ligand poses and affinity rankings (journal article) Gaieb, Zied \| Parks, Conor D. \| Chiu, Michael \| Yang, Huanwang \| Shao, Chenghua \| Walters, W. Patrick \| Lambert, Millard H. \| Nevins, Neysa \| Bembenek, Scott D. \| Ameriks, Michael K. \| ... \| Gilson, Michael K. Journal of Computer-Aided Molecular Design, volume 33, issue 1, pages 1-18 (2019). 10.1007/s10822-018-0180-4 Cited by (92) \| Cite \| Source
Predicting the Binding of Fatty Acid Amide Hydrolase Inhibitors by Free Energy Perturbation (journal article) Saha, Arjun \| Shih, Amy Y. \| Mirzadegan, Taraneh \| Seierstad, Mark Journal of Chemical Theory and Computation, volume 14, issue 11, pages 5815-5822 (2018). 10.1021/acs.jctc.8b00672 Cited by (16) \| Cite \| Source
An Analysis of Different Components of a High-Throughput Screening Library (journal article) Saha, Arjun \| Varghese, Teena \| Liu, Annie \| Allen, Samantha J. \| Mirzadegan, Taraneh \| Hack, Michael D. Journal of Chemical Information and Modeling, volume 58, issue 10, pages 2057-2068 (2018). 10.1021/acs.jcim.8b00258 Cited by (10) \| Cite \| Source
Determination of a Focused Mini Kinase Panel for Early Identification of Selective Kinase Inhibitors (journal article) Bembenek, Scott D. \| Hirst, Gavin \| Mirzadegan, Taraneh Journal of Chemical Information and Modeling, volume 58, issue 7, pages 1434-1440 (2018). 10.1021/acs.jcim.8b00222 Cited by (14) \| Cite \| Source
Dynamic Structural Differences between Human and Mouse STING Lead to Differing Sensitivity to DMXAA (journal article) Shih, Amy Y. \| Damm-Ganamet, Kelly L. \| Mirzadegan, Taraneh Biophysical Journal, volume 114, issue 1, pages 32-39 (2018). 10.1016/j.bpj.2017.10.027 Cited by (64) \| Cite \| Source
Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein–Protein Interaction (journal article) Blevitt, Jonathan M. \| Hack, Michael D. \| Herman, Krystal L. \| Jackson, Paul F. \| Krawczuk, Paul J. \| Lebsack, Alec D. \| Liu, Annie X. \| Mirzadegan, Taraneh \| Nelen, Marina I. \| Patrick, Aaron N. \| ... \| Lumb, Kevin J. Journal of Medicinal Chemistry, volume 60, issue 8, pages 3511-3517 (2017). 10.1021/acs.jmedchem.6b01836 Cited by (50) \| Cite \| Source
Computational chemistry at Janssen (journal article) van Vlijmen, Herman \| Desjarlais, Renee L. \| Mirzadegan, Tara Journal of Computer-Aided Molecular Design, volume 31, issue 3, pages 267-273 (2017). 10.1007/s10822-016-9998-9 Cited by (14) \| Cite \| Source
Structural Basisof Small-Molecule Aggregate InducedInhibition of a Protein–Protein Interaction (journal article) JonathanM., Blevitt \| D., Hack Michael \| L., Herman Krystal \| F., Jackson Paul \| J., Krawczuk Paul \| D, Lebsack Alec \| X., Liu Annie \| Taraneh, Mirzadegan \| I., Nelen Marina \| N., Patrick Aaron \| ... \| J., Lumb Kevin Journal of Medicinal Chemistry (2017). 10.1021/acs.jmedchem.6b01836.s001 Cite \| Source
A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors (journal article) Blevitt, Jonathan M. \| Hack, Michael D. \| Herman, Krystal \| Chang, Leon \| Keith, John M. \| Mirzadegan, Tara \| Rao, Navin L. \| Lebsack, Alec D. \| Milla, Marcos E. Journal of Biological Chemistry, volume 291, issue 24, pages 12724-12731 (2016). 10.1074/jbc.M116.725325 Cited by (11) \| Cite \| Source \| Open Access
A Prospective Virtual Screening Study: Enriching Hit Rates and Designing Focus Libraries To Find Inhibitors of PI3Kδ and PI3Kγ (journal article) Damm-Ganamet, Kelly L. \| Bembenek, Scott D. \| Venable, Jennifer W. \| Castro, Glenda G. \| Mangelschots, Lieve \| Peeters, Daniëlle C. G. \| Mcallister, Heather M. \| Edwards, James P. \| Disepio, Daniel \| Mirzadegan, Taraneh Journal of Medicinal Chemistry, volume 59, issue 9, pages 4302-4313 (2016). 10.1021/acs.jmedchem.5b01974 Cited by (24) \| Cite \| Source
Phenyl linked quinolinyl modulators of RORγt (patent) Leonard, Kristi A. \| Barbay, Kent \| Edwards, James P. \| Kreutter, Kevin D. \| Kummer, David A. \| Maharoof, Umar \| Nishimura, Rachel \| Urbanski, Maud \| Venkatesan, Hariharan \| Wang, Aihua \| ... \| Ganamet, Kelly Patent Number: 9309222 (2016) Cited by (9) \| Cite \| Source
PHENYL LINKED QUINOLINYL MODULATORS OF RORgammat (patent) Leonard, Kristi A. \| Barbay, Kent \| Edwards, James P. \| Kreutter, Kevin D. \| Kummer, David A. \| Maharoof, Umar \| Nishimura, Rachel \| Urbanski, Maud \| Venkatesan, Hariharan \| Wang, Aihua \| ... \| Ganamet, Kelly Lynn Patent Number: 20160279122 (2015) Cite \| Source
Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV (μ-TRTX-Hh2a) (journal article) Minassian, Natali A. \| Gibbs, Alan \| Shih, Amy Y. \| Liu, Yi \| Neff, Robert A. \| Sutton, Steven W. \| Mirzadegan, Tara \| Connor, Judith \| Fellows, Ross \| Husovsky, Matthew \| ... \| Wickenden, Alan D. Journal of Biological Chemistry, volume 288, issue 31, pages 22707-22720 (2013). 10.1074/jbc.M113.461392 Cited by (65) \| Cite \| Source \| Open Access
Aryl-substituted bridged or fused diamines as modulators of leukotriene Ahydrolase (patent) Kearney, Aaron M. \| Landry-Bayle, Adrienne M. \| Santillán,, Alejandro \| Lee-Dutra, Alice \| Grice, Cheryl A. \| Bacani, Genesis M. \| Edwards, James P. \| McClure, Kelly J. \| Gomez, Laurent \| Bembenek, Scott D. \| ... \| Eccles, Wendy Patent Number: 8367719 (2013) Cite \| Source