Beatrice Mercorelli

ScholarGPS® ID: 38191347834654

Affiliation

University of Padua, Padua, Italy

Affiliation History

Field

Life Sciences

Discipline

Molecular and Cell Biology

Top Specialties

Cytomegalovirus | Influenza | Antiviral Drug | Virus

Metrics Summary

Publication Count

Predicted Citations

2,043

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

Add Delete
Design, synthesis, and biological evaluation of first-in-class indomethacin-based PROTACs degrading SARS-CoV-2 main protease and with broad-spectrum antiviral activity (journal article) Desantis, Jenny \| Bazzacco, Alessandro \| Eleuteri, Michela \| Tuci, Sara \| Bianconi, Elisa \| Macchiarulo, Antonio \| Mercorelli, Beatrice \| Loregian, Arianna \| Goracci, Laura European Journal of Medicinal Chemistry, volume 268 (2024). 10.1016/j.ejmech.2024.116202 Cited by (2) \| Cite \| Source
Human neural progenitor cell models to study the antiviral effects and neuroprotective potential of approved and investigational human cytomegalovirus inhibitors (journal article) Trevisan, Marta \| Pianezzola, Anna \| Onorati, Marco \| Apolloni, Lorenzo \| Pistello, Mauro \| Arav-Boger, Ravit \| Palù, Giorgio \| Mercorelli, Beatrice \| Loregian, Arianna Antiviral Research, volume 223 (2024). 10.1016/j.antiviral.2024.105816 Cite \| Source
Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability (journal article) Gao, Shenghua \| Song, Letian \| Sylvester, Katharina \| Mercorelli, Beatrice \| Loregian, Arianna \| Toth, Karoly \| Weiße, Renato H. \| Useini, Abibe \| Sträter, Norbert \| Yang, Mianling \| ... \| Zhan, Peng Journal of Medicinal Chemistry, volume 66, issue 23, pages 16426-16440 (2023). 10.1021/acs.jmedchem.3c01876 Cited by (3) \| Cite \| Source
A small molecule targeting the interaction between human papillomavirus E7 oncoprotein and cellular phosphatase PTPN14 exerts antitumoral activity in cervical cancer cells (journal article) Bertagnin, Chiara \| Messa, Lorenzo \| Pavan, Matteo \| Celegato, Marta \| Sturlese, Mattia \| Mercorelli, Beatrice \| Moro, Stefano \| Loregian, Arianna Cancer Letters, volume 571 (2023). 10.1016/j.canlet.2023.216331 Cited by (5) \| Cite \| Source
Small-Molecule Inhibitor of Flaviviral NS3-NS5 Interaction with Broad-Spectrum Activity and Efficacy In Vivo (journal article) Celegato, Marta \| Sturlese, Mattia \| Vasconcelos Costa, Vivian \| Trevisan, Marta \| Lallo Dias, Angélica Samer \| Souza Passos, Ingredy Beatriz \| Queiroz-Junior, Celso Martins \| Messa, Lorenzo \| Favaro, Annagiulia \| Moro, Stefano \| ... \| Mercorelli, Beatrice mBio, volume 14, issue 1 (2023). 10.1128/mbio.03097-22 Cited by (5) \| Cite \| Source
Discovery of novel SARS-CoV-2 inhibitors targeting the main protease Mpro by virtual screenings and hit optimization (journal article) Mercorelli, Beatrice \| Desantis, Jenny \| Celegato, Marta \| Bazzacco, Alessandro \| Siragusa, Lydia \| Benedetti, Paolo \| Eleuteri, Michela \| Croci, Federico \| Cruciani, Gabriele \| Goracci, Laura \| Loregian, Arianna Antiviral Research, volume 204 (2022). 10.1016/j.antiviral.2022.105350 Cited by (13) \| Cite \| Source
Targeted Disruption of E6/p53 Binding Exerts Broad Activity and Synergism with Paclitaxel and Topotecan against HPV-Transformed Cancer Cells (journal article) Celegato, Marta \| Messa, Lorenzo \| Bertagnin, Chiara \| Mercorelli, Beatrice \| Loregian, Arianna Cancers, volume 14, issue 1, pages 193- (2021). 10.3390/cancers14010193 Cited by (7) \| Cite \| Source
Repurposing Approved Drugs to Block Highly Pathogenic Emerging Viruses (book chapter) In Antiviral Discovery for Highly Pathogenic Emerging Viruses Mercorelli, B. \| Loregian, A. The Royal Society of Chemistry (2021) 10.1039/9781788016858-00232 Cite \| Source
Indomethacin-based PROTACs as pan-coronavirus antiviral agents (journal article) Desantis, Jenny \| Mercorelli, Beatrice \| Celegato, Marta \| Croci, Federico \| Bazzacco, Alessandro \| Baroni, Massimo \| Siragusa, Lydia \| Cruciani, Gabriele \| Loregian, Arianna \| Goracci, Laura European Journal of Medicinal Chemistry, volume 226 (2021). 10.1016/j.ejmech.2021.113814 Cited by (49) \| Cite \| Source
The Dimeric Form of HPV16 E6 Is Crucial to Drive YAP/TAZ Upregulation through the Targeting of hScrib (journal article) Messa, Lorenzo \| Celegato, Marta \| Bertagnin, Chiara \| Mercorelli, Beatrice \| Alvisi, Gualtiero \| Banks, Lawrence \| Palù, Giorgio \| Loregian, Arianna Cancers, volume 13, issue 16, pages 4083- (2021). 10.3390/cancers13164083 Cited by (8) \| Cite \| Source
Divide et impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication (journal article) Ghassabian, Hanieh \| Falchi, Federico \| Timmoneri, Martina \| Mercorelli, Beatrice \| Loregian, Arianna \| Palù, Giorgio \| Alvisi, Gualtiero Viruses, volume 13, issue 5, pages 941- (2021). 10.3390/v13050941 Cited by (1) \| Cite \| Source
The antifungal drug isavuconazole inhibits the replication of human cytomegalovirus (HCMV) and acts synergistically with anti-HCMV drugs (journal article) Mercorelli, Beatrice \| Celegato, Marta \| Luganini, Anna \| Gribaudo, Giorgio \| Lepesheva, Galina I. \| Loregian, Arianna Antiviral Research, volume 189 (2021). 10.1016/j.antiviral.2021.105062 Cited by (5) \| Cite \| Source
The Clinically Approved Antifungal Drug Posaconazole Inhibits Human Cytomegalovirus Replication (journal article) Mercorelli, Beatrice \| Luganini, Anna \| Celegato, Marta \| Palù, Giorgio \| Gribaudo, Giorgio \| Lepesheva, Galina I. \| Loregian, Arianna Antimicrobial Agents and Chemotherapy, volume 64, issue 10 (2020). 10.1128/AAC.00056-20 Cited by (20) \| Cite \| Source
A novel small-molecule inhibitor of the human papillomavirus E6-p53 interaction that reactivates p53 function and blocks cancer cells growth (journal article) Celegato, Marta \| Messa, Lorenzo \| Goracci, Laura \| Mercorelli, Beatrice \| Bertagnin, Chiara \| Spyrakis, Francesca \| Suarez, Irina \| Cousido-Siah, Alexandra \| Travé, Gilles \| Banks, Lawrence \| ... \| Loregian, Arianna Cancer Letters, volume 470 (2020). 10.1016/j.canlet.2019.10.046 Cited by (37) \| Cite \| Source
Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance (journal article) Nannetti, Giulio \| Massari, Serena \| Mercorelli, Beatrice \| Bertagnin, Chiara \| Desantis, Jenny \| Palù, Giorgio \| Tabarrini, Oriana \| Loregian, Arianna Antiviral Research, volume 165 (2019). 10.1016/j.antiviral.2019.03.003 Cited by (21) \| Cite \| Source
The isoquinoline alkaloid berberine inhibits human cytomegalovirus replication by interfering with the viral Immediate Early-2 (IE2) protein transactivating activity. (journal article) Luganini, Anna \| Mercorelli, Beatrice \| Messa, Lorenzo \| Palù, Giorgio \| Gribaudo, Giorgio \| Loregian, Arianna Antiviral Research, volume 164 (2019). 10.1016/j.antiviral.2019.02.006 Cited by (39) \| Cite \| Source
Drug Repurposing Campaigns for Human Cytomegalovirus Identify a Natural Compound Targeting the Immediate-Early 2 (IE2) Protein: A Comment on “The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts” (journal article) Mercorelli, Beatrice \| Luganini, Anna \| Palù, Giorgio \| Gribaudo, Giorgio \| Loregian, Arianna Viruses, volume 11, issue 2, pages 117- (2019). 10.3390/v11020117 Cited by (5) \| Cite \| Source
Drug Repurposing for Viral Infectious Diseases: How Far Are We? (journal article) Mercorelli, Beatrice \| Palù, Giorgio \| Loregian, Arianna Trends in Microbiology, volume 26, issue 10, pages 865-876 (2018). 10.1016/j.tim.2018.04.004 Cited by (181) \| Cite \| Source
A quantitative LumiFluo assay to test inhibitory compounds blocking p53 degradation induced by human papillomavirus oncoprotein E6 in living cells (journal article) Messa, Lorenzo \| Celegato, Marta \| Bertagnin, Chiara \| Mercorelli, Beatrice \| Nannetti, Giulio \| Palù, Giorgio \| Loregian, Arianna Scientific Reports, volume 8, issue 1 (2018). 10.1038/s41598-018-24470-4 Cited by (10) \| Cite \| Source \| Open Access
Repurposing the clinically approved calcium antagonist manidipine dihydrochloride as a new early inhibitor of human cytomegalovirus targeting the Immediate-Early 2 (IE2) protein (journal article) Mercorelli, Beatrice \| Luganini, Anna \| Celegato, Marta \| Palù, Giorgio \| Gribaudo, Giorgio \| Loregian, Arianna Antiviral Research, volume 150 (2018). 10.1016/j.antiviral.2017.12.014 Cited by (21) \| Cite \| Source