Georgios Skiniotis

ScholarGPS® ID: 37223890759050

Highly Ranked Scholar - Prior Five Years:

Protein complex

Affiliation

Stanford University, Stanford, United States

Affiliation History

Field

Life Sciences

Discipline

Physiology

Top Specialties

Metrics Summary

Publication Count

136

Predicted Citations

17,409

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor (journal article) Batebi, Hossein \| Pérez-Hernández, Guillermo \| Rahman, Sabrina N. \| Lan, Baoliang \| Kamprad, Antje \| Shi, Mingyu \| Speck, David \| Tiemann, Johanna K. S. \| Guixà-González, Ramon \| Reinhardt, Franziska \| ... \| Hildebrand, Peter W. Nature Structural & Molecular Biology (2024). 10.1038/s41594-024-01334-2 Cite \| Source
Time-resolved cryo-EM of G-protein activation by a GPCR (journal article) Papasergi-Scott, Makaía M. \| Pérez-Hernández, Guillermo \| Batebi, Hossein \| Gao, Yang \| Eskici, Gözde \| Seven, Alpay B. \| Panova, Ouliana \| Hilger, Daniel \| Casiraghi, Marina \| He, Feng \| ... \| Skiniotis, Georgios Nature, volume 629, issue 8014, pages 1182-1191 (2024). 10.1038/s41586-024-07153-1 Cited by (8) \| Cite \| Source
Allosteric modulation and G-protein selectivity of the Ca2+-sensing receptor (journal article) He, Feng \| Wu, Cheng-Guo \| Gao, Yang \| Rahman, Sabrina N. \| Zaoralová, Magda \| Papasergi-Scott, Makaía M. \| Gu, Ting-Jia \| Robertson, Michael J. \| Seven, Alpay B. \| Li, Lingjun \| ... \| Skiniotis, Georgios Nature, volume 626, issue 8001, pages 1141-1148 (2024). 10.1038/s41586-024-07055-2 Cited by (6) \| Cite \| Source
Hexahydroquinoline Derivatives Are Selective Agonists for the Adhesion G Protein-Coupled Receptor ADGRG1/GPR56 (journal article) Vizurraga, Alexander L. \| Robertson, Michael J. \| Yu, Maiya \| Skiniotis, Georgios \| Tall, Gregory G. Molecular Pharmacology, volume 104, issue 1, pages 28-41 (2023). 10.1124/molpharm.123.000688 Cited by (1) \| Cite \| Source
Structural basis for activation of CB1 by an endocannabinoid analog (journal article) Krishna Kumar, Kaavya \| Robertson, Michael J. \| Thadhani, Elina \| Wang, Haoqing \| Suomivuori, Carl-Mikael \| Powers, Alexander S. \| Ji, Lipin \| Nikas, Spyros P. \| Dror, Ron O. \| Inoue, Asuka \| ... \| Kobilka, Brian Nature Communications, volume 14, issue 1 (2023). 10.1038/s41467-023-37864-4 Cited by (14) \| Cite \| Source
Insights into distinct signaling profiles of the µOR activated by diverse agonists (journal article) Qu, Qianhui \| Huang, Weijiao \| Aydin, Deniz \| Paggi, Joseph M. \| Seven, Alpay B. \| Wang, Haoqing \| Chakraborty, Soumen \| Che, Tao \| DiBerto, Jeffrey F. \| Robertson, Michael J. \| ... \| Skiniotis, Georgios Nature Chemical Biology, volume 19, issue 4, pages 423-430 (2023). 10.1038/s41589-022-01208-y Cited by (46) \| Cite \| Source
Structure determination of inactive-state GPCRs with a universal nanobody (journal article) Robertson, Michael J. \| Papasergi-Scott, Makaía M. \| He, Feng \| Seven, Alpay B. \| Meyerowitz, Justin G. \| Panova, Ouliana \| Peroto, Maria Claudia \| Che, Tao \| Skiniotis, Georgios Nature Structural & Molecular Biology, volume 29, issue 12, pages 1188-1195 (2022). 10.1038/s41594-022-00859-8 Cited by (44) \| Cite \| Source
Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD (journal article) Cao, Can \| Barros-Álvarez, Ximena \| Zhang, Shicheng \| Kim, Kuglae \| Dämgen, Marc A. \| Panova, Ouliana \| Suomivuori, Carl-Mikael \| Fay, Jonathan F. \| Zhong, Xiaofang \| Krumm, Brian E. \| ... \| Roth, Bryan L. Neuron, volume 110, issue 19, pages 3154-3167.e7 (2022). 10.1016/j.neuron.2022.08.006 Cited by (58) \| Cite \| Source
Asymmetric activation of the calcium-sensing receptor homodimer (journal article) Gao, Y \| Robertson, MJ \| Rahman, SN \| Seven, AB \| Zhang, C \| Meyerowitz, JG \| Panova, O \| Hannan, FM \| Thakker, RV \| Brauner-Osborne, H \| ... \| Skiniotis, G Yearbook of Paediatric Endocrinology (2022). 10.1530/ey.19.5.15 Cite \| Source
Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns (journal article) Chen, Geng \| Wang, Xiankun \| Liao, Qiwen \| Ge, Yunjun \| Jiao, Haizhan \| Chen, Qiang \| Liu, Yezhou \| Lyu, Wenping \| Zhu, Lizhe \| van Zundert, Gydo C. P. \| ... \| Ye, Richard D. Nature Communications, volume 13, issue 1 (2022). 10.1038/s41467-022-32822-y Cited by (19) \| Cite \| Source
Development of OPLS-AA/M Parameters for Simulations of G Protein-Coupled Receptors and Other Membrane Proteins (journal article) Robertson, Michael J. \| Skiniotis, Georgios Journal of Chemical Theory and Computation, volume 18, issue 7, pages 4482-4489 (2022). 10.1021/acs.jctc.2c00015 Cited by (10) \| Cite \| Source
Structure‐Based Evolution of G Protein‐Biased μ‐Opioid Receptor Agonists (journal article) Wang, Haoqing \| Hetzer, Florian \| Huang, Weijiao \| Qu, Qianhui \| Meyerowitz, Justin \| Kaindl, Jonas \| Hübner, Harald \| Skiniotis, Georgios \| Kobilka, Brian K. \| Gmeiner, Peter Angewandte Chemie International Edition, volume 61, issue 26 (2022). 10.1002/anie.202200269 Cited by (30) \| Cite \| Source
Strukturbasierte Entwicklung von G‐Protein bevorzugenden μ‐Opioidrezeptor Agonisten (journal article) Wang, Haoqing \| Hetzer, Florian \| Huang, Weijiao \| Qu, Qianhui \| Meyerowitz, Justin \| Kaindl, Jonas \| Hübner, Harald \| Skiniotis, Georgios \| Kobilka, Brian K. \| Gmeiner, Peter Angewandte Chemie, volume 134, issue 26 (2022). 10.1002/ange.202200269 Cite \| Source
The tethered peptide activation mechanism of adhesion GPCRs (journal article) Barros-Álvarez, Ximena \| Nwokonko, Robert M. \| Vizurraga, Alexander \| Matzov, Donna \| He, Feng \| Papasergi-Scott, Makaía M. \| Robertson, Michael J. \| Panova, Ouliana \| Yardeni, Eliane Hadas \| Seven, Alpay B. \| ... \| Skiniotis, Georgios Nature, volume 604, issue 7907, pages 757-762 (2022). 10.1038/s41586-022-04575-7 Cited by (56) \| Cite \| Source
The oxytocin signaling complex reveals a molecular switch for cation dependence (journal article) Meyerowitz, Justin G. \| Robertson, Michael J. \| Barros-Álvarez, Ximena \| Panova, Ouliana \| Nwokonko, Robert M. \| Gao, Yang \| Skiniotis, Georgios Nature Structural & Molecular Biology, volume 29, issue 3, pages 274-281 (2022). 10.1038/s41594-022-00728-4 Cited by (26) \| Cite \| Source
Plasticity in ligand recognition at somatostatin receptors (journal article) Robertson, Michael J. \| Meyerowitz, Justin G. \| Panova, Ouliana \| Borrelli, Kenneth \| Skiniotis, Georgios Nature Structural & Molecular Biology, volume 29, issue 3, pages 210-217 (2022). 10.1038/s41594-022-00727-5 Cited by (26) \| Cite \| Source
Drug discovery in the era of cryo-electron microscopy (journal article) Robertson, Michael J. \| Meyerowitz, Justin G. \| Skiniotis, Georgios Trends in Biochemical Sciences, volume 47, issue 2, pages 124-135 (2022). 10.1016/j.tibs.2021.06.008 Cited by (45) \| Cite \| Source
Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins (journal article) Tsutsumi, Naotaka \| Maeda, Shoji \| Qu, Qianhui \| Vögele, Martin \| Jude, Kevin M. \| Suomivuori, Carl-Mikael \| Panova, Ouliana \| Waghray, Deepa \| Kato, Hideaki E. \| Velasco, Andrew \| ... \| Garcia, K. Christopher Science Advances, volume 8, issue 3 (2022). 10.1126/sciadv.abl5442 Cited by (14) \| Cite \| Source
Structure and mechanism of the SGLT family of glucose transporters (journal article) Han, Lei \| Qu, Qianhui \| Aydin, Deniz \| Panova, Ouliana \| Robertson, Michael J. \| Xu, Yan \| Dror, Ron O. \| Skiniotis, Georgios \| Feng, Liang Nature, volume 601, issue 7892, pages 274-279 (2022). 10.1038/s41586-021-04211-w Cited by (54) \| Cite \| Source
Contributors (book chapter) In Genomics in Biosecurity Boltsis, Ilias \| Bourodimos, Lampros E. \| Chassomeris, Constantinos A. \| Georgoulas, Dimitris \| Gioula, Georgia \| Kambouris, Manousos E. \| Kantzanou, Maria \| Kostis, George D. \| Manoussopoulos, Yiannis \| Papathanassiou, Athanasios-Foivos B. \| ... \| Velegraki, Aristea Elsevier (2022) 10.1016/B978-0-323-85236-4.09992-1 Cite \| Source

Title	Investigators	Year	Cost	Agency
Structure and dynamics of G protein coupled receptor-G protein complexes	Kobilka, Brian K. \| Skiniotis, Georgios \| Sunahara, Roger K	2020	$502,225	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
The Stanford SLAC CryoEM Center	Chiu, WAH \| Hedman, Britt \| Schmid, Michael F. \| Skiniotis, Georgios	2019	$7,690,000	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Structural Basis of Signal Instigation Through Metabotropic Glutamate Receptors	Skiniotis, Georgios	2019	$89,601	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
The Stanford-SLAC CryoEM Center	Chiu, WAH \| Hedman, Britt \| Schmid, Michael F. \| Skiniotis, Georgios	2019	$4,709,102	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Structural Basis of Signal Instigation Through Metabotropic Glutamate Receptors	Skiniotis, Georgios	2019	$729,780	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
The Stanford-SLAC CryoEM Center	Chiu, WAH \| Hedman, Britt \| Schmid, Michael F. \| Skiniotis, Georgios	2018	$8,513,821	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Structural Basis of Substrate Processing in Modular Polyketide Synthases	Skiniotis, Georgios	2018	$398,196	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Structural Basis of Signal Instigation Through Metabotropic Glutamate Receptors	Skiniotis, Georgios	2018	$734,961	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Architectural Basis of Leptin Transmembrane Signaling	Skiniotis, Georgios	2017	$8,943	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Structural Basis of Signal Instigation Through Metabotropic Glutamate Receptors	Skiniotis, Georgios	2017	$416,437	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Structural Basis of Substrate Processing in Modular Polyketide Synthases	Skiniotis, Georgios	2017	$331,045	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Architectural Basis of Leptin Transmembrane Signaling	Skiniotis, Georgios	2017	$106,336	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Structural Basis of Signal Instigation Through Metabotropic Glutamate Receptors	Skiniotis, Georgios	2017	$191,256	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Structural basis of substrate processing in modular polyketide synthases	Skiniotis, Georgios	2017	$72,808	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Structural basis of substrate processing in modular polyketide synthases	Skiniotis, Georgios	2016	$420,332	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Structural Basis of Signal Instigation Through Metabotropic Glutamate Receptors	Skiniotis, Georgios	2016	$614,443	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Architectural Basis of Leptin Transmembrane Signaling	Skiniotis, Georgios	2016	$341,772	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Structural basis of substrate processing in modular polyketide synthases	Skiniotis, Georgios	2015	$420,332	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Structural Basis of Signal Instigation Through Metabotropic Glutamate Receptors	Skiniotis, Georgios	2015	$629,267	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Silicon Mechanics Compute Cluster	Skiniotis, Georgios	2015	$490,238	OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEALTH
Architectural Basis of Leptin Transmembrane Signaling	Skiniotis, Georgios	2015	$341,772	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Architectural Basis of Leptin Transmembrane Signaling	Skiniotis, Georgios	2014	$341,962	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Architectural Basis of Leptin Transmembrane Signaling	Skiniotis, Georgios	2013	$2,488	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Architectural Basis of Leptin Transmembrane Signaling	Skiniotis, Georgios	2013	$388,478	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Architectural Basis of Leptin Transmembrane Signaling	Skiniotis, Georgios	2012	$60,420	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Architectural Basis of Leptin Transmembrane Signaling	Skiniotis, Georgios	2012	$342,327	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Architectural Basis of Leptin Transmembrane Signaling	Skiniotis, Georgios	2011	$381,660	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
BUILDING STRUCTURAL MODELS FOR THE RSC CHROMATIN REMODELING COMPLEX	Skiniotis, Georgios	2009	$45,684	NATIONAL CENTER FOR RESEARCH RESOURCES