Melinda Roy

ScholarGPS® ID: 37145308279432

Affiliation

University of California, San Diego, San Diego, United States

Affiliation History

Field

Life Sciences

Discipline

Biochemistry

Top Specialties

Protein Kinase | Structural Biology | Binding Protein | Calcium-binding Protein

Metrics Summary

Publication Count

Predicted Citations

3,156

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Altered Backbone and Side-Chain Interactions Result in Route Heterogeneity during the Folding of Interleukin-1β (IL-1β) (journal article) Capraro, Dominique T. \| Lammert, Heiko \| Heidary, David K. \| Roy, Melinda \| Gross, Larry A. \| Onuchic, José N. \| Jennings, Patricia A. Biophysical Journal, volume 105, issue 4, pages 975-983 (2013). 10.1016/j.bpj.2013.06.019 Cited by (4) \| Cite \| Source \| Open Access
Folding Circular Permutants of IL-1β: Route Selection Driven by Functional Frustration (journal article) Capraro, Dominique T. \| Gosavi, Shachi \| Roy, Melinda \| Onuchic, José N. \| Jennings, Patricia A. PLoS ONE, volume 7, issue 6, pages e38512- (2012). 10.1371/journal.pone.0038512 Cited by (22) \| Cite \| Source \| Open Access
β-Bulge triggers route-switching on the functional landscape of interleukin-1β (journal article) Capraro, Dominique T. \| Roy, Melinda \| Onuchic, José N. \| Gosavi, Shachi \| Jennings, Patricia A. Proceedings of the National Academy of Sciences, volume 109, issue 5, pages 1490-1493 (2012). 10.1073/pnas.1114430109 Cited by (25) \| Cite \| Source \| Open Access
Allostery in the ferredoxin protein motif does not involve a conformational switch (journal article) Nechushtai, Rachel \| Lammert, Heiko \| Michaeli, Dorit \| Eisenberg-Domovich, Yael \| Zuris, John A. \| Luca, Maria A. \| Capraro, Dominique T. \| Fish, Alex \| Shimshon, Odelia \| Roy, Melinda \| ... \| Jennings, Patricia A. Proceedings of the National Academy of Sciences, volume 108, issue 6, pages 2240-2245 (2011). 10.1073/pnas.1019502108 Cited by (28) \| Cite \| Source \| Open Access
Titration and p H Measurement (book chapter) In Encyclopedia of Life Sciences Jennings, Patricia A \| Mullen, Christine A \| Roy, Melinda Wiley (2010) 10.1002/9780470015902.a0002700.pub2 Cite \| Source
Pro-interleukin (IL)-1β Shares a Core Region of Stability as Compared with Mature IL-1β While Maintaining a Distinctly Different Configurational Landscape (journal article) Hailey, Kendra L. \| Li, Sheng \| Andersen, Mette D. \| Roy, Melinda \| Woods, Virgil L. \| Jennings, Patricia A. Journal of Biological Chemistry, volume 284, issue 38, pages 26137-26148 (2009). 10.1074/jbc.M109.027375 Cited by (25) \| Cite \| Source \| Open Access
Chromophore Packing Leads to Hysteresis in GFP (journal article) Andrews, Benjamin T. \| Roy, Melinda \| Jennings, Patricia A. Journal of Molecular Biology, volume 392, issue 1, pages 218-227 (2009). 10.1016/j.jmb.2009.06.072 Cited by (27) \| Cite \| Source \| Open Access
The novel 2Fe–2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain (journal article) Conlan, Andrea R. \| Paddock, Mark L. \| Axelrod, Herbert L. \| Cohen, Aina E. \| Abresch, Edward C. \| Wiley, Sandra \| Roy, Melinda \| Nechushtai, Rachel \| Jennings, Patricia A. Acta Crystallographica Section F Structural Biology and Crystallization Communications, volume 65, issue 7, pages 654-659 (2009). 10.1107/S1744309109019605 Cited by (18) \| Cite \| Source \| Open Access
Backtracking on the folding landscape of the β-trefoil protein interleukin-1β? (journal article) Capraro, Dominique T. \| Roy, Melinda \| Onuchic, José N. \| Jennings, Patricia A. Proceedings of the National Academy of Sciences, volume 105, issue 39, pages 14844-14848 (2008). 10.1073/pnas.0807812105 Cited by (65) \| Cite \| Source \| Open Access
The Rough Energy Landscape of Superfolder GFP Is Linked to the Chromophore (journal article) Andrews, Benjamin T. \| Schoenfish, Andrea R. \| Roy, Melinda \| Waldo, Geoffrey \| Jennings, Patricia A. Journal of Molecular Biology, volume 373, issue 2, pages 476-490 (2007). 10.1016/j.jmb.2007.07.071 Cited by (66) \| Cite \| Source \| Open Access
MitoNEET is a uniquely folded 2Fe–2S outer mitochondrial membrane protein stabilized by pioglitazone (journal article) Paddock, Mark L. \| Wiley, Sandra E. \| Axelrod, Herbert L. \| Cohen, Aina E. \| Roy, Melinda \| Abresch, Edward C. \| Capraro, Dominique \| Murphy, Anne N. \| Nechushtai, Rachel \| Dixon, Jack E. \| Jennings, Patricia A. Proceedings of the National Academy of Sciences, volume 104, issue 36, pages 14342-14347 (2007). 10.1073/pnas.0707189104 Cited by (233) \| Cite \| Source \| Open Access
Long-range Coupling Between Separate Docking Sites in Interleukin-1β (journal article) Heidary, David K. \| Roy, Melinda \| Daumy, Gaston O. \| Cong, Yang \| Jennings, Patricia A. Journal of Molecular Biology, volume 353, issue 5, pages 1187-1198 (2005). 10.1016/j.jmb.2005.08.072 Cited by (21) \| Cite \| Source
The Native Energy Landscape for Interleukin-1β. Modulation of the Population Ensemble through Native-state Topology (journal article) Roy, Melinda \| Chavez, Leslie L. \| Finke, John M. \| Heidary, David K. \| Onuchic, José N. \| Jennings, Patricia A. Journal of Molecular Biology, volume 348, issue 2, pages 335-347 (2005). 10.1016/j.jmb.2005.02.059 Cited by (29) \| Cite \| Source \| Open Access
Tumor imaging by means of proteolytic activation of cell-penetrating peptides (journal article) Jiang, Tao \| Olson, Emilia S. \| Nguyen, Quyen T. \| Roy, Melinda \| Jennings, Patricia A. \| Tsien, Roger Y. Proceedings of the National Academy of Sciences, volume 101, issue 51, pages 17867-17872 (2004). 10.1073/pnas.0408191101 Cited by (758) \| Cite \| Source \| Open Access
Studies of Structure-Activity Relations of Complement Inhibitor Compstatin (journal article) Soulika, Athena M. \| Morikis, Dimitrios \| Sarrias, Maria-Rosa \| Roy, Melinda \| Spruce, Lynn A. \| Sahu, Arvind \| Lambris, John D. The Journal of Immunology, volume 171, issue 4, pages 1881-1890 (2003). 10.4049/jimmunol.171.4.1881 Cited by (40) \| Cite \| Source \| Open Access
Related Protein–Protein Interaction Modules Present Drastically Different Surface Topographies Despite A Conserved Helical Platform (journal article) Banky, Poopak \| Roy, Melinda \| Newlon, Marceen G \| Morikis, Dimitrios \| Haste, Nina M \| Taylor, Susan S \| Jennings, Patricia A Journal of Molecular Biology, volume 330, issue 5, pages 1117-1129 (2003). 10.1016/S0022-2836(03)00552-7 Cited by (58) \| Cite \| Source \| Open Access
Real-time NMR Kinetic Studies Provide Global and Residue-specific Information on the Non-cooperative Unfolding of the β-Trefoil Protein, Interleukin-1β (journal article) Roy, Melinda \| Jennings, Patricia A Journal of Molecular Biology, volume 328, issue 3, pages 693-703 (2003). 10.1016/S0022-2836(03)00340-1 Cited by (28) \| Cite \| Source
Real-time NMR kinetic studies provide global and residue-specific information on the non-cooperative unfolding of the beta-trefoil protein, interleukin-1beta. (journal article) Roy, Melinda \| Jennings, Patricia A Journal of molecular biology, volume 328, issue 3 (2003). Cite
The Structural Basis of Compstatin Activity Examined by Structure-Function-based Design of Peptide Analogs and NMR (journal article) Morikis, Dimitrios \| Roy, Melinda \| Sahu, Arvind \| Troganis, Anastasios \| Jennings, Patricia A. \| Tsokos, George C. \| Lambris, John D. Journal of Biological Chemistry, volume 277, issue 17, pages 14942-14953 (2002). 10.1074/jbc.M200021200 Cited by (55) \| Cite \| Source \| Open Access
Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIα (journal article) Morikis, Dimitrios \| Roy, Melinda \| Newlon, Marceen G. \| Scott, John D. \| Jennings, Patricia A. European Journal of Biochemistry, volume 269, issue 8, pages 2040-2051 (2002). 10.1046/j.1432-1033.2002.02852.x Cited by (13) \| Cite \| Source \| Open Access