Gabriele Fenini

ScholarGPS® ID: 36914027389138

Affiliation

University of Zurich, Zürich, Switzerland

Affiliation History

Field

Medicine

Discipline

Dermatology

Top Specialties

Inflammasome | Macrophage | Melanoma

Metrics Summary

Publication Count

Predicted Citations

1,129

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Efficient Generation of CRISPR/Cas9-Mediated Knockout Human Primary Keratinocytes by Electroporation (book chapter) In Methods in Molecular Biology Karakaya, Tugay \| Slaufova, Marta \| Di Filippo, Michela \| Hennig, Paulina \| Fenini, Gabriele \| Kündig, Thomas \| Beer, Hans-Dietmar Springer US (2024) 10.1007/7651_2024_518 Cite \| Source
NLRP1 Inflammasome Activation in Keratinocytes: Increasing Evidence of Important Roles in Inflammatory Skin Diseases and Immunity (journal article) Fenini, Gabriele \| Karakaya, Tugay \| Hennig, Paulina \| Di Filippo, Michela \| Slaufova, Marta \| Beer, Hans-Dietmar Journal of Investigative Dermatology, volume 142, issue 9, pages 2313-2322 (2022). 10.1016/j.jid.2022.04.004 Cited by (11) \| Cite \| Source
Phosphodiesterase-4 Inhibition Reduces Cutaneous Inflammation and IL-1β Expression in a Psoriasiform Mouse Model but Does Not Inhibit Inflammasome Activation (journal article) Meier-Schiesser, Barbara \| Mellett, Mark \| Ramirez-Fort, Marigdalia K. \| Maul, Julia-Tatjana \| Klug, Annika \| Winkelbeiner, Nicola \| Fenini, Gabriele \| Schafer, Peter \| Contassot, Emmanuel \| French, Lars E. International Journal of Molecular Sciences, volume 22, issue 23, pages 12878- (2021). 10.3390/ijms222312878 Cited by (3) \| Cite \| Source
The Pathways Underlying the Multiple Roles of p62 in Inflammation and Cancer (journal article) Hennig, Paulina \| Fenini, Gabriele \| Di Filippo, Michela \| Karakaya, Tugay \| Beer, Hans-Dietmar Biomedicines, volume 9, issue 7, pages 707- (2021). 10.3390/biomedicines9070707 Cited by (39) \| Cite \| Source
The NLRP1 Inflammasome in Human Skin and Beyond (journal article) Fenini, Gabriele \| Karakaya, Tugay \| Hennig, Paulina \| Di Filippo, Michela \| Beer, Hans-Dietmar International Journal of Molecular Sciences, volume 21, issue 13, pages 4788- (2020). 10.3390/ijms21134788 Cited by (59) \| Cite \| Source
Inactivation of the Cytoprotective Major Vault Protein by Caspase-1 and -9 in Epithelial Cells during Apoptosis (journal article) Grossi, Serena \| Fenini, Gabriele \| Kockmann, Tobias \| Hennig, Paulina \| Di Filippo, Michela \| Beer, Hans-Dietmar Journal of Investigative Dermatology, volume 140, issue 7, pages 1335-1345.e10 (2020). 10.1016/j.jid.2019.11.015 Cited by (21) \| Cite \| Source
IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes (journal article) Satoh, Takashi K. \| Mellett, Mark \| Meier-Schiesser, Barbara \| Fenini, Gabriele \| Otsuka, Atsushi \| Beer, Hans-Dietmar \| Rordorf, Tamara \| Maul, Julia-Tatjana \| Hafner, Jürg \| Navarini, Alexander A. \| ... \| French, Lars E. Journal of Clinical Investigation, volume 130, issue 3, pages 1417-1430 (2020). 10.1172/JCI128678 Cited by (36) \| Cite \| Source
Electrophiles against (Skin) Diseases: More Than Nrf2 (journal article) Hennig, Paulina \| Fenini, Gabriele \| Di Filippo, Michela \| Beer, Hans-Dietmar Biomolecules, volume 10, issue 2, pages 271- (2020). 10.3390/biom10020271 Cited by (22) \| Cite \| Source
The NLRP1 Inflammasome Pathway Is Silenced in Cutaneous Squamous Cell Carcinoma (journal article) Sand, Jennifer \| Fenini, Gabriele \| Grossi, Serena \| Hennig, Paulina \| Di Filippo, Michela \| Levesque, Mitchell \| Werner, Sabine \| French, Lars E. \| Beer, Hans-Dietmar Journal of Investigative Dermatology, volume 139, issue 8, pages 1788-1797.e6 (2019). 10.1016/j.jid.2019.01.025 Cited by (17) \| Cite \| Source
Generation of Knockout Human Primary Keratinocytes by CRISPR/Cas9 (book chapter) In Epidermal Cells Grossi, Serena \| Fenini, Gabriele \| Hennig, Paulina \| Di Filippo, Michela \| Beer, Hans-Dietmar Springer US (2019) 10.1007/7651_2019_262 Cited by (5) \| Cite \| Source
Genome Editing of Human Primary Keratinocytes by CRISPR/Cas9 Reveals an Essential Role of the NLRP1 Inflammasome in UVB Sensing (journal article) Fenini, Gabriele \| Grossi, Serena \| Contassot, Emmanuel \| Biedermann, Thomas \| Reichmann, Ernst \| French, Lars E. \| Beer, Hans-Dietmar Journal of Investigative Dermatology, volume 138, issue 12, pages 2644-2652 (2018). 10.1016/j.jid.2018.07.016 Cited by (77) \| Cite \| Source
The p38 Mitogen-Activated Protein Kinase Critically Regulates Human Keratinocyte Inflammasome Activation (journal article) Fenini, Gabriele \| Grossi, Serena \| Gehrke, Samuel \| Beer, Hans-Dietmar \| Satoh, Takashi K. \| Contassot, Emmanuel \| French, Lars E. Journal of Investigative Dermatology, volume 138, issue 6, pages 1380-1390 (2018). 10.1016/j.jid.2017.10.037 Cited by (27) \| Cite \| Source
994 In contrast to myeloid cells, inflammasome activation in keratinocytes is dependent on JNK1 and p38 mitogen-activated protein kinases (journal article) Fenini, G. \| Grossi, S. \| Gehrke, S. \| Beer, H. \| Satoh, T.K. \| Contassot, E. \| French, L.E. Journal of Investigative Dermatology, volume 138, issue 5, pages S169- (2018). 10.1016/j.jid.2018.03.1006 Cite \| Source
Microcrystalline Tyrosine and Aluminum as Adjuvants in Allergen-Specific Immunotherapy Protect from IgE-Mediated Reactivity in Mouse Models and Act Independently of Inflammasome and TLR Signaling (journal article) Leuthard, Deborah S. \| Duda, Agathe \| Freiberger, Sandra N. \| Weiss, Sina \| Dommann, Isabella \| Fenini, Gabriele \| Contassot, Emmanuel \| Kramer, Matthias F. \| Skinner, Murray A. \| Kündig, Thomas M. \| ... \| Johansen, Pål The Journal of Immunology, volume 200, issue 9, pages 3151-3159 (2018). 10.4049/jimmunol.1800035 Cited by (40) \| Cite \| Source \| Open Access
Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases (journal article) Fenini, Gabriele \| Contassot, Emmanuel \| French, Lars E. Frontiers in Pharmacology, volume 8 (2017). 10.3389/fphar.2017.00278 Cited by (90) \| Cite \| Source \| Open Access
Opposing effects of Nrf2 and Nrf2‐activating compounds on the NLRP3 inflammasome independent of Nrf2‐mediated gene expression (journal article) Garstkiewicz, Martha \| Strittmatter, Gerhard E. \| Grossi, Serena \| Sand, Jennifer \| Fenini, Gabriele \| Werner, Sabine \| French, Lars E. \| Beer, Hans‐Dietmar European Journal of Immunology, volume 47, issue 5, pages 806-817 (2017). 10.1002/eji.201646665 Cited by (46) \| Cite \| Source
High-mobility-group-Box1 (HMGB1) promotes melanoma progression through the recruitment of M2 macrophages (journal article) Huber, Roman \| Otsuka, Atsushi \| Meier, Barbara \| Widmer, Daniel \| Satoh, Takashi \| Fenini, Gabriele \| Mangana, Johanna \| Proust, Tatiana \| Dummer, Reinhard \| Contassot, Emmanuel \| French, Lars E. Journal of Dermatological Science, volume 84, issue 1, pages e84- (2016). 10.1016/j.jdermsci.2016.08.257 Cite \| Source
Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages (journal article) Huber, Roman \| Meier, Barbara \| Otsuka, Atsushi \| Fenini, Gabriele \| Satoh, Takashi \| Gehrke, Samuel \| Widmer, Daniel \| Levesque, Mitchell P. \| Mangana, Joanna \| Kerl, Katrin \| ... \| French, Lars E. Scientific Reports, volume 6, issue 1 (2016). 10.1038/srep29914 Cited by (102) \| Cite \| Source \| Open Access
Malassezia yeasts activate the NLRP 3 inflammasome in antigen‐presenting cells via S yk‐kinase signalling (journal article) Kistowska, Magdalena \| Fenini, Gabriele \| Jankovic, Dragana \| Feldmeyer, Laurence \| Kerl, Katrin \| Bosshard, Philipp \| Contassot, Emmanuel \| French, Lars E. Experimental Dermatology, volume 23, issue 12, pages 884-889 (2014). 10.1111/exd.12552 Cited by (64) \| Cite \| Source
Metastatic melanoma cell lines do not secrete IL-1β but promote IL-1β production from macrophages (journal article) Gehrke, Samuel \| Otsuka, Atsushi \| Huber, Roman \| Meier, Barbara \| Kistowska, Magdalena \| Fenini, Gabriele \| Cheng, Phil \| Dummer, Reinhard \| Kerl, Katrin \| Contassot, Emmanuel \| French, Lars E. Journal of Dermatological Science, volume 74, issue 2, pages 167-169 (2014). 10.1016/j.jdermsci.2014.01.006 Cited by (13) \| Cite \| Source