Joseph A. Martin

ScholarGPS® ID: 36530229095369

Affiliation

Roche Palo Alto LLC

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

2,790

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

Add Delete
4′-substituted nucleoside derivatives as inhibitors of HCV RNA replication (patent) Devos, Rene Robert \| Hobbs, Christopher John \| Jiang, Wen-Rong \| Martin, Joseph Armstrong \| Merrett, John Herbert \| Najera, Isabel \| Shimma, Nobuo \| Tsukuda, Takuo Patent Number: 8648054 (2014) Cite \| Source
4′-substituted nucleoside derivatives as inhibitors of HCV RNA replication (patent) Devos, Rene Robert \| Hobbs, Christopher John \| Jiang, Wen Rong \| Martin, Joseph Armstrong \| Merrett, John Herbert \| Najera, Isabel \| Shimma, Nobuo \| Tsukuda, Takuo Patent Number: 8071567 (2011) Cited by (32) \| Cite \| Source
4′-substituted nucleoside derivatives as inhibitors of HCV RNA replication (patent) Martin, Joseph Armstrong \| Merrett, John Herbert \| Najera, Isabel \| Devos, Rene Robert \| Hobbs, Christopher John \| Jiang, Wen Rong \| Shimma, Nobuo \| Tsukuda, Takuo Patent Number: 7915232 (2011) Cited by (24) \| Cite \| Source
4′-Substituted nucleoside derivatives as inhibitors of HCV RNA replication (patent) Devos, Rene Robert \| Hobbs, Christopher John \| Jiang, Wen Rong \| Martin, Joseph Armstrong \| Merrett, John Herbert \| Najera, Isabel \| Shimma, Nobuo \| Tsukuda, Takuo Patent Number: 7608601 (2009) Cited by (33) \| Cite \| Source
Antiviral phosphoramidates (patent) Klumpp, Klaus \| Martin, Joseph Armstrong \| McGuigan, Christopher \| Smith, David Bernard Patent Number: 7608599 (2009) Cited by (43) \| Cite \| Source
The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4′-azidocytidine (R1479) (journal article) McGuigan, Christopher \| Kelleher, Mary Rose \| Perrone, Plinio \| Mulready, Sinead \| Luoni, Giovanna \| Daverio, Felice \| Rajyaguru, Sonal \| Pogam, Sophie Le \| Najera, Isabel \| Martin, Joseph A. \| ... \| Smith, David B. Bioorganic & Medicinal Chemistry Letters, volume 19, issue 15, pages 4250-4254 (2009). 10.1016/j.bmcl.2009.05.099 Cited by (74) \| Cite \| Source
The application of the phosphoramidate ProTide approach confers micromolar potency against Hepatitis C virus on inactive agent 4′-azidoinosine: Kinase bypass on a dual base/sugar modified nucleoside (journal article) McGuigan, Christopher \| Daverio, Felice \| Nájera, Isabel \| Martin, Joseph A. \| Klumpp, Klaus \| Smith, David B. Bioorganic & Medicinal Chemistry Letters, volume 19, issue 11, pages 3122-3124 (2009). 10.1016/j.bmcl.2009.03.138 Cited by (31) \| Cite \| Source
The Design, Synthesis, and Antiviral Activity of Monofluoro and Difluoro Analogues of 4′-Azidocytidine against Hepatitis C Virus Replication: The Discovery of 4′-Azido-2′-deoxy-2′-fluorocytidine and 4′-Azido-2′-dideoxy-2′,2′-difluorocytidine (journal article) Smith, David B. \| Kalayanov, Genadiy \| Sund, Christian \| Winqvist, Anna \| Maltseva, Tatiana \| Leveque, Vincent J.-P. \| Rajyaguru, Sonal \| Pogam, Sophie Le \| Najera, Isabel \| Benkestock, Kurt \| ... \| Smith, Mark Journal of Medicinal Chemistry, volume 52, issue 9, pages 2971-2978 (2009). 10.1021/jm801595c Cited by (88) \| Cite \| Source
The Design, Synthesis, and Antiviral Activity of 4′-Azidocytidine Analogues against Hepatitis C Virus Replication: The Discovery of 4′-Azidoarabinocytidine (journal article) Smith, David B. \| Kalayanov, Genadiy \| Sund, Christian \| Winqvist, Anna \| Pinho, Pedro \| Maltseva, Tatiana \| Morisson, Veronique \| Leveque, Vincent \| Rajyaguru, Sonal \| Pogam, Sophie Le \| ... \| Smith, Mark Journal of Medicinal Chemistry, volume 52, issue 1, pages 219-223 (2009). 10.1021/jm800981y Cited by (45) \| Cite \| Source
Anti-viral nucleosides (patent) Martin, Joseph Armstrong \| Sarma, Keshab \| Smith, David Bernard \| Smith, Mark Patent Number: 7378402 (2008) Cited by (50) \| Cite \| Source
2′-Deoxy-4′-azido Nucleoside Analogs Are Highly Potent Inhibitors of Hepatitis C Virus Replication Despite the Lack of 2′-α-Hydroxyl Groups (journal article) Klumpp, Klaus \| Kalayanov, Genadiy \| Ma, Han \| Le Pogam, Sophie \| Leveque, Vincent \| Jiang, Wen-Rong \| Inocencio, Nicole \| De Witte, Anniek \| Rajyaguru, Sonal \| Tai, Ezra \| ... \| Smith, David B. Journal of Biological Chemistry, volume 283, issue 4, pages 2167-2175 (2008). 10.1074/jbc.M708929200 Cited by (84) \| Cite \| Source \| Open Access
First Example of Phosphoramidate Approach Applied to a 4‘-Substituted Purine Nucleoside (4‘-Azidoadenosine): Conversion of an Inactive Nucleoside to a Submicromolar Compound versus Hepatitis C Virus (journal article) Perrone, Plinio \| Daverio, Felice \| Valente, Rocco \| Rajyaguru, Sonal \| Martin, Joseph A. \| Lévêque, Vincent \| Pogam, Sophie Le \| Najera, Isabel \| Klumpp, Klaus \| Smith, David B. \| McGuigan, Christopher Journal of Medicinal Chemistry, volume 50, issue 22, pages 5463-5470 (2007). 10.1021/jm070362i Cited by (80) \| Cite \| Source
Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479 (journal article) Smith, David B. \| Martin, Joseph A. \| Klumpp, Klaus \| Baker, Stewart J. \| Blomgren, Peter A. \| Devos, Rene \| Granycome, Caroline \| Hang, Julie \| Hobbs, Christopher J. \| Jiang, Wen-Rong \| ... \| Cammack, Nick Bioorganic & Medicinal Chemistry Letters, volume 17, issue 9, pages 2570-2576 (2007). 10.1016/j.bmcl.2007.02.004 Cited by (102) \| Cite \| Source
Application of the Phosphoramidate ProTide Approach to 4‘-Azidouridine Confers Sub-micromolar Potency versus Hepatitis C Virus on an Inactive Nucleoside (journal article) Perrone, Plinio \| Luoni, Giovanna M. \| Kelleher, Mary Rose \| Daverio, Felice \| Angell, Annette \| Mulready, Sinead \| Congiatu, Costantino \| Rajyaguru, Sonal \| Martin, Joseph A. \| Levêque, Vincent \| ... \| McGuigan, Christopher Journal of Medicinal Chemistry, volume 50, issue 8, pages 1840-1849 (2007). 10.1021/jm0613370 Cited by (129) \| Cite \| Source
The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture (journal article) Klumpp, Klaus \| Lévêque, Vincent \| Le Pogam, Sophie \| Ma, Han \| Jiang, Wen-Rong \| Kang, Hyunsoon \| Granycome, Caroline \| Singer, Margaret \| Laxton, Carl \| Hang, Julie Qi \| ... \| Nájera, Isabel Journal of Biological Chemistry, volume 281, issue 7, pages 3793-3799 (2006). 10.1074/jbc.M510195200 Cited by (223) \| Cite \| Source \| Open Access
Anhydrous crystalline 1-[4(S)-azido-2(S),3(R)-dihydroxy-4-(hydroxymethyl)-1(R)-cyclopentyl]cytosine hemisulfate as useful as an antiviral agent (patent) Connolly, Terrence Joseph \| Martin, Joseph Armstrong \| Prince, Anthony \| Sarma, Keshab Patent Number: 6864244 (2005) Cited by (13) \| Cite \| Source
Antiviral nucleoside derivatives (patent) Martin, Joseph Armstrong \| Sarma, Keshab \| Smith, David Bernard \| Smith, Mark Patent Number: 6846810 (2005) Cited by (107) \| Cite \| Source
4′-substituted nucleoside derivatives as inhibitors of HCV RNA replication. (patent) Devos, Rene Robert \| Hobbs, Christopher John \| Jiang, Wen Rong \| Martin, Joseph Armstrong \| Merrett, John Herbert \| Najera, Isabel \| Shimma, Nobuo \| Tsukuda, Takuo Patent Number: 6784166 (2004) Cited by (56) \| Cite \| Source
Methods and compositions for treating viral diseases (patent) Martin, Joseph Armstrong Patent Number: 20040152661 (2004) Cite \| Source
Activity of the isolated HIV RNase H domain and specific inhibition by N-hydroxyimides (journal article) Hang, Julie Qi \| Rajendran, Surendran \| Yang, Yanli \| Li, Yu \| Wong Kai In, Philippe \| Overton, Hilary \| Parkes, Kevin E.B. \| Cammack, Nick \| Martin, Joseph A. \| Klumpp, Klaus Biochemical and Biophysical Research Communications, volume 317, issue 2, pages 321-329 (2004). 10.1016/j.bbrc.2004.03.061 Cited by (48) \| Cite \| Source