Kristina B. Kooiker

ScholarGPS® ID: 36274754470214

Affiliation

University of Washington, Seattle, United States

Affiliation History

Field

Medicine

Discipline

Pediatrics

Top Specialties

Cardiomyopathy | Mutation | Biophysics | Hypertrophic Cardiomyopathy

Metrics Summary

Publication Count

Predicted Citations

786

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic cardiomyopathy (journal article) Steczina, Sonette \| Mohran, Saffie \| Bailey, Logan R.J. \| McMillen, Timothy S. \| Kooiker, Kristina B. \| Wood, Neil B. \| Davis, Jennifer \| Previs, Michael J. \| Olivotto, Iacopo \| Pioner, Josè Manuel \| ... \| Regnier, Michael Journal of Molecular and Cellular Cardiology, volume 191 (2024). 10.1016/j.yjmcc.2024.04.010 Cite \| Source
Decoupling calcium-dependent thin-filament activation from thick-filament activation in porcine myocardium (journal article) Mohran, Saffie \| Mandrycky, Christian \| Tu, An-yue \| McMillen, Tim \| Kooiker, Kristina B. \| Qian, Wenjing \| Irving, Thomas C. \| Regnier, Michael \| Ma, Weikang Biophysical Journal, volume 123, issue 3, pages 520a- (2024). 10.1016/j.bpj.2023.11.3150 Cite \| Source
2-Deoxy-ATP reduces the cardiac depressive effect of acidosis (journal article) Redd, Meredith A. \| McMillen, Tim S. \| Woodward, Mike K. \| Mohran, Saffie \| Kooiker, Kristina B. \| Flint, Galina V. \| Suresh, Laavan \| Moussavi-Harami, Farid \| Davis, Jennifer \| Debold, Edward P. \| Regnier, Michael Biophysical Journal, volume 123, issue 3, pages 403a-404a (2024). 10.1016/j.bpj.2023.11.2469 Cite \| Source
MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient-induced stem cell-derived cardiomyocyte model of hypertrophic cardiomyopathy (journal article) Steczina, Sonette \| Mohran, Saffie \| Bailey, Logan \| McMillen, Tim \| Kooiker, Kristina B. \| Wood, Neil B. \| Davis, Jennifer M. \| Previs, Michael J. \| Olivotto, Iacopo \| Pioner, J. Manuel \| ... \| Regnier, Michael Biophysical Journal, volume 123, issue 3, pages 318a-319a (2024). 10.1016/j.bpj.2023.11.1955 Cite \| Source
The effect of small molecule myosin inhibitors on ATP cycling in porcine cardiac muscle using stopped-flow spectroscopy and in vitro motility (journal article) Mahoney-Schaefer, Max \| Kooiker, Kristina B. \| Mohran, Saffie \| Flint, Galina V. \| Regnier, Michael \| Moussavi-Harami, Farid Biophysical Journal, volume 123, issue 3, pages 266a-267a (2024). 10.1016/j.bpj.2023.11.1670 Cite \| Source
Mechanisms of myosin, myofibril, and cardiomyocyte dysfunction with the MYH7 R403Q mutation in porcine ventricle muscle (journal article) Mohran, Saffie \| Steczina, Sonette \| Kooiker, Kristina B. \| McMillen, Timothy \| Mandrycky, Christian \| Childers, Matthew C. \| Kao, Kerry Y. \| Yu, Jingyuan \| Jiang, Siyao \| Irving, Thomas C. \| ... \| Regnier, Michael Biophysical Journal, volume 123, issue 3, pages 267a- (2024). 10.1016/j.bpj.2023.11.1671 Cite \| Source
Echocardiography to Assess Cardiac Structure and Function in Genetic Cardiomyopathies (book chapter) In Familial Cardiomyopathies Flint, Galina \| Kooiker, Kristina \| Moussavi-Harami, Farid Springer US (2024) 10.1007/978-1-0716-3527-8_1 Cite \| Source
Hypertrophic cardiomyopathy in purpose-bred cats with the A31P mutation in cardiac myosin binding protein-C (journal article) Stern, Joshua A. \| Rivas, Victor N. \| Kaplan, Joanna L. \| Ueda, Yu \| Oldach, Maureen S. \| Ontiveros, Eric S. \| Kooiker, Kristina B. \| van Dijk, Sabine J. \| Harris, Samantha P. Scientific Reports, volume 13, issue 1 (2023). 10.1038/s41598-023-36932-5 Cited by (3) \| Cite \| Source
Machine learning meets Monte Carlo methods for models of muscle’s molecular machinery to classify mutations (journal article) Asencio, Anthony \| Malingen, Sage \| Kooiker, Kristina B. \| Powers, Joseph D. \| Davis, Jennifer \| Daniel, Thomas \| Moussavi-Harami, Farid Journal of General Physiology, volume 155, issue 5 (2023). 10.1085/jgp.202213291 Cited by (2) \| Cite \| Source
Elucidating the mechanism of Danicamtiv on force, kinetics, and myosin structure and function (journal article) Kooiker, Kristina B. \| Mohran, Saffie \| Ma, Weikang \| Flint, Galina V. \| Kao, Kerry Y. \| Qi, Lin \| McMillen, Timothy \| Neys, Stephanie \| Mandrycky, Christian \| Irving, Thomas C. \| ... \| Moussavi-Harami, Farid Biophysical Journal, volume 122, issue 3, pages 453a- (2023). 10.1016/j.bpj.2022.11.2439 Cite \| Source
The effect of small molecule myosin modulators on ATP turnover in pig cardiac HMM using stopped flow spectroscopy (journal article) Kooiker, Kristina B. \| Mohran, Saffie \| Mahoney-Schaefer, Max \| Freeman, Jeremy \| Geeves, Michael A. \| Regnier, Michael \| Moussavi-Harami, Farid Biophysical Journal, volume 122, issue 3, pages 121a-122a (2023). 10.1016/j.bpj.2022.11.827 Cite \| Source
Altered Cardiac Energetics and Mitochondrial Dysfunction in Hypertrophic Cardiomyopathy (journal article) Ranjbarvaziri, Sara \| Kooiker, Kristina B. \| Ellenberger, Mathew \| Fajardo, Giovanni \| Zhao, Mingming \| Vander Roest, Alison Schroer \| Woldeyes, Rahel A. \| Koyano, Tiffany T. \| Fong, Robyn \| Ma, Ning \| ... \| Bernstein, Daniel Circulation, volume 144, issue 21, pages 1714-1731 (2021). 10.1161/CIRCULATIONAHA.121.053575 Cited by (106) \| Cite \| Source
Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super relaxed state (journal article) Vander Roest, Alison Schroer \| Liu, Chao \| Morck, Makenna M. \| Kooiker, Kristina Bezold \| Jung, Gwanghyun \| Song, Dan \| Dawood, Aminah \| Jhingran, Arnav \| Pardon, Gaspard \| Ranjbarvaziri, Sara \| ... \| Bernstein, Daniel Proceedings of the National Academy of Sciences, volume 118, issue 24 (2021). 10.1073/pnas.2025030118 Cited by (41) \| Cite \| Source
The Progression of Dystrophin-Deficient Dilated Cardiomyopathy through Mechanical and Ca2+ Dysfunction in a Duchenne Muscular Dystrophy Rat Model (journal article) Mohran, Saffie \| Luttrell, Shawn M. \| McMillen, Tim \| Kooiker, Kristina B. \| Mack, David L. \| Regnier, Michael Biophysical Journal, volume 120, issue 3, pages 253a- (2021). 10.1016/j.bpj.2020.11.1640 Cite \| Source
Molecular Mechanisms and Cellular Models of Hypertrophic Cardiomyopathy: Insights from a Surprising Mutation (journal article) Roest, Alison S. Vander \| Liu, Chao \| Kooiker, Kristina B. \| Morck, Makenna M. \| Pruitt, Beth \| Campbell, Kenneth S. \| Ruppel, Kathleen \| Spudich, James A. \| Bernstein, Daniel Biophysical Journal, volume 120, issue 3, pages 253a- (2021). 10.1016/j.bpj.2020.11.1639 Cite \| Source
4HNE Impairs Myocardial Bioenergetics in Congenital Heart Disease-Induced Right Ventricular Failure (journal article) Hwang, HyunTae V. \| Sandeep, Nefthi \| Paige, Sharon L. \| Ranjbarvaziri, Sara \| Hu, Dong-Qing \| Zhao, Mingming \| Lan, Ingrid S. \| Coronado, Michael \| Kooiker, Kristina B. \| Wu, Sean M. \| ... \| Reddy, Sushma Circulation, volume 142, issue 17, pages 1667-1683 (2020). 10.1161/CIRCULATIONAHA.120.045470 Cited by (14) \| Cite \| Source
Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts (journal article) Powers, Joseph D. \| Kooiker, Kristina B. \| Mason, Allison B. \| Teitgen, Abigail E. \| Flint, Galina V. \| Tardiff, Jil C. \| Schwartz, Steven D. \| McCulloch, Andrew D. \| Regnier, Michael \| Davis, Jennifer \| Moussavi-Harami, Farid JCI Insight, volume 5, issue 20 (2020). 10.1172/jci.insight.142446 Cited by (15) \| Cite \| Source
Ribonucleotide Reductase is Essential in Adult Cardiomyocytes (journal article) Kooiker, Kristina B. \| Berisha, Djelli \| Martinson, Amy \| Tudor, Joelle \| Freeman, Jeremy \| Branley, Claire \| Moussavi-Harami, Farid Biophysical Journal, volume 118, issue 3, pages 257a- (2020). 10.1016/j.bpj.2019.11.1494 Cite \| Source
Two Myofilament-Based Approaches to Prevent Genetic Dilated Cardiomyopathy (journal article) Branley, Claire E. \| Moussavi-Harami, Farid \| Kooiker, Kristina B. \| Regnier, Michael \| Tardiff, Jil C. \| Tudor, Joelle \| Freeman, Jeremy Biophysical Journal, volume 118, issue 3, pages 594a- (2020). 10.1016/j.bpj.2019.11.3216 Cite \| Source
Two Small Molecule Inhibitors of Myosin Decrease Force and Increase Rates of Relaxation in Demembranated Rat Left Ventricular Tissue (journal article) Kooiker, Kristina B. \| Gan, Qing-Fen \| Yu, Ming \| Cheng, Yuanhua \| Sa, Na \| Zhong, Min \| McMillen, Tim \| Moussavi-Harami, Farid \| Regnier, Michael Biophysical Journal, volume 118, issue 3, pages 327a- (2020). 10.1016/j.bpj.2019.11.1832 Cite \| Source