Shawn T. Beug

ScholarGPS® ID: 35954848364926

Affiliation

University of Ottawa, Ottawa, Canada

Affiliation History

Field

Medicine

Discipline

Immunology

Top Specialties

Neoplasm | Apoptosis | Cell Death

Metrics Summary

Publication Count

Predicted Citations

936

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Suspension-Induced Stem Cell Transition: A Non-Transgenic Method to Generate Adult Stem Cells from Mouse and Human Somatic Cells (journal article) Yeganeh, Behzad \| Yeganeh, Azadeh \| Malone, Kyle \| Beug, Shawn T. \| Jankov, Robert P. Cells, volume 12, issue 20, pages 2508- (2023). 10.3390/cells12202508 Cite \| Source
LCL161 enhances expansion and survival of engineered anti-tumor T cells but is restricted by death signaling (journal article) Afsahi, Arya \| Silvestri, Christopher M. \| Moore, Allyson E. \| Graham, Carly F. \| Bacchiochi, Kaylyn \| St-Jean, Martine \| Baker, Christopher L. \| Korneluk, Robert G. \| Beug, Shawn T. \| LaCasse, Eric C. \| Bramson, Jonathan L. Frontiers in Immunology, volume 14 (2023). 10.3389/fimmu.2023.1179827 Cite \| Source
Adaptation of transgene mRNA translation boosts the anticancer efficacy of oncolytic HSV1 (journal article) Hoang, Huy-Dung \| Said, Aida \| Vaidya, Nasana \| Gilchrist, Victoria H \| Malone, Kyle \| Kabilan, Usha \| Topshee, Serena \| Xiang, Xiao \| Yang, An-Dao \| Olagnier, David \| ... \| Alain, Tommy Journal for ImmunoTherapy of Cancer, volume 11, issue 3, pages e006408- (2023). 10.1136/jitc-2022-006408 Cited by (1) \| Cite \| Source
Role of Ceramides and Lysosomes in Extracellular Vesicle Biogenesis, Cargo Sorting and Release (journal article) Horbay, Rostyslav \| Hamraghani, Ali \| Ermini, Leonardo \| Holcik, Sophie \| Beug, Shawn T. \| Yeganeh, Behzad International Journal of Molecular Sciences, volume 23, issue 23, pages 15317- (2022). 10.3390/ijms232315317 Cited by (20) \| Cite \| Source
Autophagy in Tumor Immunity and Viral-Based Immunotherapeutic Approaches in Cancer (journal article) Zahedi-Amiri, Ali \| Malone, Kyle \| Beug, Shawn T. \| Alain, Tommy \| Yeganeh, Behzad Cells, volume 10, issue 10, pages 2672- (2021). 10.3390/cells10102672 Cited by (6) \| Cite \| Source
4E-BP–Dependent Translational Control of Irf8 Mediates Adipose Tissue Macrophage Inflammatory Response (journal article) Pearl, Dana \| Katsumura, Sakie \| Amiri, Mehdi \| Tabatabaei, Negar \| Zhang, Xu \| Vinette, Valerie \| Pang, Xinhe \| Beug, Shawn T. \| Kim, Sung-Hoon \| Jones, Laura M. \| ... \| Tahmasebi, Soroush The Journal of Immunology, volume 204, issue 9, pages 2392-2400 (2020). 10.4049/jimmunol.1900538 Cited by (12) \| Cite \| Source
SMC combination therapy for the treatment of cancer (patent) Korneluk, Robert G. \| Lacasse, Eric C. \| Beug, Shawn T. \| Tang, Vera A. Patent Number: 10441654 (2019) Cite \| Source
Sp3-cificity of TNF-α expression promotes the Smac mimetic-mediated killing of cancer cells (journal article) Beug, Shawn T. \| Korneluk, Robert G. \| LaCasse, Eric C. Molecular & Cellular Oncology, volume 6, issue 4, pages 1607456- (2019). 10.1080/23723556.2019.1607456 Cited by (2) \| Cite \| Source
The transcription factor SP3 drives TNF-α expression in response to Smac mimetics (journal article) Beug, Shawn T. \| Cheung, Herman H. \| Sanda, Tarun \| St-Jean, Martine \| Beauregard, Caroline E. \| Mamady, Hapsatou \| Baird, Stephen D. \| LaCasse, Eric C. \| Korneluk, Robert G. Science Signaling, volume 12, issue 566 (2019). 10.1126/scisignal.aat9563 Cited by (7) \| Cite \| Source
Combination of IAP Antagonists and TNF-α-Armed Oncolytic Viruses Induce Tumor Vascular Shutdown and Tumor Regression (journal article) Beug, Shawn T. \| Pichette, Stephanie J. \| St-Jean, Martine \| Holbrook, Janelle \| Walker, Danielle E. \| LaCasse, Eric C. \| Korneluk, Robert G. Molecular Therapy - Oncolytics, volume 10 (2018). 10.1016/j.omto.2018.06.002 Cited by (21) \| Cite \| Source \| Open Access
Inhibitor of apoptosis proteins, NAIP, cIAP1 and cIAP2 expression during macrophage differentiation and M1/M2 polarization (journal article) Morón-Calvente, Virginia \| Romero-Pinedo, Salvador \| Toribio-Castelló, Sofía \| Plaza-Díaz, Julio \| Abadía-Molina, Ana C. \| Rojas-Barros, Domingo I. \| Beug, Shawn T. \| LaCasse, Eric C. \| MacKenzie, Alex \| Korneluk, Robert \| Abadía-Molina, Francisco PLOS ONE, volume 13, issue 3, pages e0193643- (2018). 10.1371/journal.pone.0193643 Cited by (31) \| Cite \| Source \| Open Access
Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma (journal article) Beug, Shawn T. \| Beauregard, Caroline E. \| Healy, Cristin \| Sanda, Tarun \| St-Jean, Martine \| Chabot, Janelle \| Walker, Danielle E. \| Mohan, Aditya \| Earl, Nathalie \| Lun, Xueqing \| ... \| Korneluk, Robert G. Nature Communications, volume 8, issue 1 (2017). 10.1038/ncomms14278 Cited by (99) \| Cite \| Source \| Open Access
Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model (journal article) Dobson, Christine C. \| Naing, Thet \| Beug, Shawn T. \| Faye, Mame D. \| Chabot, Janelle \| St-Jean, Martin \| Walker, Danielle E. \| LaCasse, Eric C. \| Stojdl, David F. \| Korneluk, Robert G. \| Holcik, Martin Oncotarget, volume 8, issue 2, pages 3495-3508 (2017). 10.18632/oncotarget.13849 Cited by (22) \| Cite \| Source \| Open Access
Sortilin regulates sorting and secretion of Sonic hedgehog (journal article) Campbell, Charles \| Beug, Shawn \| Nickerson, Philip E. B. \| Peng, Jimmy \| Mazerolle, Chantal \| Bassett, Erin A. \| Ringuette, Randy \| Jama, Fadumo A. \| Morales, Carlos \| Christ, Annabel \| Wallace, Valerie A. Development, volume 143, issue 21, pages e1.2-e1.2 (2016). 10.1242/dev.145870 Cite \| Source \| Open Access
Sortilin regulates sorting and secretion of Sonic hedgehog (journal article) Campbell, Charles \| Beug, Shawn \| Nickerson, Philip E. B. \| Peng, Jimmy \| Mazerolle, Chantal \| Bassett, Erin A. \| Ringuette, Randy \| Jama, Fadumo A. \| Morales, Carlos \| Christ, Annabel \| Wallace, Valerie A. Journal of Cell Science, volume 129, issue 20, pages 3832-3844 (2016). 10.1242/jcs.183541 Cited by (11) \| Cite \| Source \| Open Access
IGF2BP1 controls cell death and drug resistance in rhabdomyosarcomas by regulating translation of cIAP1 (journal article) Faye, M D \| Beug, S T \| Graber, T E \| Earl, N \| Xiang, X \| Wild, B \| Langlois, S \| Michaud, J \| Cowan, K N \| Korneluk, R G \| Holcik, M Oncogene, volume 34, issue 12, pages 1532-1541 (2015). 10.1038/onc.2014.90 Cited by (39) \| Cite \| Source
The inhibitors of apoptosis (IAPs): Over 20 years of research into life and death (journal article) LaCasse, Eric C. \| Beug, Shawn T. \| Korneluk, Robert G. Seminars in Cell & Developmental Biology, volume 39 (2015). 10.1016/j.semcdb.2015.04.002 Cited by (2) \| Cite \| Source
Combinatorial cancer immunotherapy strategies with proapoptotic small-molecule IAP antagonists (journal article) Beug, Shawn T. \| Conrad, David P. \| Alain, Tommy \| Korneluk, Robert G. \| Lacasse, Eric C. The International Journal of Developmental Biology, volume 59, issue 1-2-3, pages 141-147 (2015). 10.1387/ijdb.150084el Cited by (16) \| Cite \| Source \| Open Access
Smac mimetics combined with innate immune stimuli create the perfect cytokine storm to kill tumor cells (journal article) Beug, Shawn T \| LaCasse, Eric C \| Korneluk, Robert G OncoImmunology, volume 3, issue 4, pages e28541- (2014). 10.4161/onci.28541 Cited by (12) \| Cite \| Source \| Open Access
Smac mimetics and innate immune stimuli synergize to promote tumor death (journal article) Beug, Shawn T \| Tang, Vera A \| LaCasse, Eric C \| Cheung, Herman H \| Beauregard, Caroline E \| Brun, Jan \| Nuyens, Jeffrey P \| Earl, Nathalie \| St-Jean, Martine \| Holbrook, Janelle \| ... \| Korneluk, Robert G Nature Biotechnology, volume 32, issue 2, pages 182-190 (2014). 10.1038/nbt.2806 Cited by (101) \| Cite \| Source \| Open Access