Zia Khan

ScholarGPS® ID: 35319026946090

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Life Sciences

Discipline

Genetics

Top Specialties

Cancer | Cancer Immunotherapy | Checkpoint Inhibitor

Metrics Summary

Publication Count

Predicted Citations

2,841

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Whole genome sequencing across clinical trials identifies rare coding variants in GPR68 associated with chemotherapy-induced peripheral neuropathy (journal article) Khan, Zia \| Jung, Min \| Crow, Megan \| Mohindra, Rajat \| Maiya, Vidya \| Kaminker, Joshua S. \| Hackos, David H. \| Chandler, G. Scott \| McCarthy, Mark I. \| Bhangale, Tushar Genome Medicine, volume 15, issue 1 (2023). 10.1186/s13073-023-01193-4 Cited by (3) \| Cite \| Source
A saturation mutagenesis screen uncovers resistant and sensitizing secondary KRAS mutations to clinical KRASG12C inhibitors (journal article) Feng, Siyu \| Callow, Marinella G. \| Fortin, Jean-Philippe \| Khan, Zia \| Bray, David \| Costa, Mike \| Shi, Zhen \| Wang, Weiru \| Evangelista, Marie Proceedings of the National Academy of Sciences, volume 119, issue 18 (2022). 10.1073/pnas.2120512119 Cited by (11) \| Cite \| Source
811 Allelic variation in Human Leukocyte Antigen class II genes is associated with pneumonitis risk in cancer patients treated with immune checkpoint inhibitors (conference) Saha, Ashis \| Spencer, Christine \| Khan, Zia \| Carroll, Jonathan \| Arellano, Claudia Yanez \| Hunkapiller, Julie \| Bayless, Nicholas \| Nissola, Leonardo \| Wallace, Roslyn \| Mellman, Ira \| ... \| Hammer, Christian SITC 36th Anniversary Annual Meeting (SITC 2021) Abstracts (2021) 10.1136/jitc-2021-SITC2021.811 Cite \| Source
ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses (journal article) Herzner, Anna-Maria \| Khan, Zia \| Van Nostrand, Eric L. \| Chan, Sara \| Cuellar, Trinna \| Chen, Ronald \| Pechuan-Jorge, Ximo \| Komuves, Laszlo \| Solon, Margaret \| Modrusan, Zora \| ... \| Albert, Matthew L. Journal of Experimental Medicine, volume 218, issue 9 (2021). 10.1084/jem.20201833 Cited by (11) \| Cite \| Source
Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade (journal article) Khan, Zia \| Hammer, Christian \| Carroll, Jonathan \| Di Nucci, Flavia \| Acosta, Sergio Ley \| Maiya, Vidya \| Bhangale, Tushar \| Hunkapiller, Julie \| Mellman, Ira \| Albert, Matthew L. \| ... \| Chandler, G. Scott Nature Communications, volume 12, issue 1 (2021). 10.1038/s41467-021-23661-4 Cited by (35) \| Cite \| Source
Autoimmunity linked protein phosphatase PTPN22 as a target for cancer immunotherapy (journal article) Cubas, Rafael \| Khan, Zia \| Gong, Qian \| Moskalenko, Marina \| Xiong, Huizhong \| Ou, Qinglin \| Pai, Christine \| Rodriguez, Ryan \| Cheung, Jeanne \| Chan, Andrew C Journal for ImmunoTherapy of Cancer, volume 8, issue 2, pages e001439- (2020). 10.1136/jitc-2020-001439 Cited by (29) \| Cite \| Source
Polygenic risk for skin autoimmunity impacts immune checkpoint blockade in bladder cancer (journal article) Khan, Zia \| Di Nucci, Flavia \| Kwan, Antonia \| Hammer, Christian \| Mariathasan, Sanjeev \| Rouilly, Vincent \| Carroll, Jonathan \| Fontes, Magnus \| Ley Acosta, Sergio \| Guardino, Ellie \| ... \| Albert, Matthew L. Proceedings of the National Academy of Sciences, volume 117, issue 22, pages 12288-12294 (2020). 10.1073/pnas.1922867117 Cited by (60) \| Cite \| Source
Mechanisms of immune-related adverse events associated with immune checkpoint blockade: using germline genetics to develop a personalized approach (journal article) Khan, Zia \| Hammer, Christian \| Guardino, Ellie \| Chandler, G. Scott \| Albert, Matthew L. Genome Medicine, volume 11, issue 1 (2019). 10.1186/s13073-019-0652-8 Cited by (55) \| Cite \| Source
Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration (journal article) Lim, Yoong Wearn \| Chen-Harris, Haiyin \| Mayba, Oleg \| Lianoglou, Steve \| Wuster, Arthur \| Bhangale, Tushar \| Khan, Zia \| Mariathasan, Sanjeev \| Daemen, Anneleen \| Reeder, Jens \| ... \| Albert, Matthew L. Proceedings of the National Academy of Sciences, volume 115, issue 50 (2018). 10.1073/pnas.1804506115 Cited by (84) \| Cite \| Source
Post-translational buffering leads to convergent protein expression levels between primates (journal article) Wang, Sidney H. \| Hsiao, Chiaowen Joyce \| Khan, Zia \| Pritchard, Jonathan K. Genome Biology, volume 19, issue 1 (2018). 10.1186/s13059-018-1451-z Cited by (25) \| Cite \| Source \| Open Access
A Methodological Assessment and Characterization of Genetically-Driven Variation in Three Human Phosphoproteomes (journal article) Engelmann, Brett W. \| Hsiao, Chiaowen Joyce \| Blischak, John D. \| Fourne, Yannick \| Khan, Zia \| Ford, Michael \| Gilad, Yoav Scientific Reports, volume 8, issue 1 (2018). 10.1038/s41598-018-30587-3 Cited by (2) \| Cite \| Source \| Open Access
Impact of regulatory variation from RNA to protein (journal article) Battle, Alexis \| Khan, Zia \| Wang, Sidney H. \| Mitrano, Amy \| Ford, Michael J. \| Pritchard, Jonathan K. \| Gilad, Yoav Science, volume 347, issue 6222, pages 664-667 (2015). 10.1126/science.1260793 Cited by (336) \| Cite \| Source \| Open Access
Stable Isotope Labeling of Phosphoproteins for Large-scale Phosphorylation Rate Determination (journal article) Molden, Rosalynn C. \| Goya, Jonathan \| Khan, Zia \| Garcia, Benjamin A. Molecular & Cellular Proteomics, volume 13, issue 4, pages 1106-1118 (2014). 10.1074/mcp.O113.036145 Cited by (27) \| Cite \| Source \| Open Access
Primate Transcript and Protein Expression Levels Evolve Under Compensatory Selection Pressures (journal article) Khan, Zia \| Ford, Michael J. \| Cusanovich, Darren A. \| Mitrano, Amy \| Pritchard, Jonathan K. \| Gilad, Yoav Science, volume 342, issue 6162, pages 1100-1104 (2013). 10.1126/science.1242379 Cited by (183) \| Cite \| Source \| Open Access
Distinct Rap1 Activity States Control the Extent of Epithelial Invagination via α-Catenin (journal article) Wang, Yu-Chiun \| Khan, Zia \| Wieschaus, Eric F. Developmental Cell, volume 25, issue 3, pages 299-309 (2013). 10.1016/j.devcel.2013.04.002 Cited by (34) \| Cite \| Source \| Open Access
Global secretome analysis identifies novel mediators of bone metastasis (journal article) Blanco, Mario Andres \| LeRoy, Gary \| Khan, Zia \| Alečković, Maša \| Zee, Barry M \| Garcia, Benjamin A \| Kang, Yibin Cell Research, volume 22, issue 9, pages 1339-1355 (2012). 10.1038/cr.2012.89 Cited by (75) \| Cite \| Source \| Open Access
BclAF1 restriction factor is neutralized by proteasomal degradation and microRNA repression during human cytomegalovirus infection (journal article) Lee, Song Hee \| Kalejta, Robert F. \| Kerry, Julie \| Semmes, Oliver John \| O’Connor, Christine M. \| Khan, Zia \| Garcia, Benjamin A. \| Shenk, Thomas \| Murphy, Eain Proceedings of the National Academy of Sciences, volume 109, issue 24, pages 9575-9580 (2012). 10.1073/pnas.1207496109 Cited by (65) \| Cite \| Source \| Open Access
Drosophila Src regulates anisotropic apical surface growth to control epithelial tube size (journal article) Nelson, Kevin S. \| Khan, Zia \| Molnár, Imre \| Mihály, József \| Kaschube, Matthias \| Beitel, Greg J. Nature Cell Biology, volume 14, issue 5, pages 518-525 (2012). 10.1038/ncb2467 Cited by (60) \| Cite \| Source \| Open Access
Differential positioning of adherens junctions is associated with initiation of epithelial folding (journal article) Wang, Yu-Chiun \| Khan, Zia \| Kaschube, Matthias \| Wieschaus, Eric F. Nature, volume 484, issue 7394, pages 390-393 (2012). 10.1038/nature10938 Cited by (132) \| Cite \| Source \| Open Access
Quantitative measurement of allele‐specific protein expression in a diploid yeast hybrid by LC‐MS (journal article) Khan, Zia \| Bloom, Joshua S \| Amini, Sasan \| Singh, Mona \| Perlman, David H \| Caudy, Amy A \| Kruglyak, Leonid Molecular Systems Biology, volume 8, issue 1 (2012). 10.1038/msb.2012.34 Cited by (30) \| Cite \| Source \| Open Access

Title	Investigators	Year	Cost	Agency
The Genetic Basis for Post-transcriptional Regulatory Variation in Humans	Khan, ZIA	2013	$14,265	NATIONAL HUMAN GENOME RESEARCH INSTITUTE
The Genetic Basis for Post-transcriptional Regulatory Variation in Humans	Khan, ZIA	2012	$47,114	NATIONAL HUMAN GENOME RESEARCH INSTITUTE