Gary S. Firestein

ScholarGPS® ID: 34946419456973

Affiliation
University of California, San Diego, San Diego, United States
Affiliation History

Field
Medicine
Discipline
Rheumatology
Top Specialties
Arthritis | Rheumatoid Arthritis | Inflammation | Cytokine | Inflammatory Arthritis | Gene Expression | Interferon | Protein Kinase Inhibitor | DNA | Macrophage | Neoplasm | Pathogenesis | Collagen | Collagen-induced Arthritis | Apoptosis
Metrics Summary
Publication Count
385
Predicted Citations
48,091
Predicted h-index
103
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Joint-specific rheumatoid arthritis fibroblast-like synoviocyte regulation identified by integration of chromatin access and transcriptional activity (journal article)
Choi, Eunice | Machado, Camilla R.L. | Okano, Takaichi | Boyle, David | Wang, Wei | Firestein, Gary S.
JCI Insight, volume 9, issue 12 (2024).
10.1172/jci.insight.179392
Cite | Source
Dysregulated NUB1 and Neddylation Enhances Rheumatoid Arthritis Fibroblast‐Like Synoviocyte Inflammatory Responses (journal article)
Sendo, Sho | Machado, Camilla R. L. | Boyle, David L. | Benschop, Robert J. | Perumal, Narayanan B. | Choi, Eunice | Wang, Wei | Firestein, Gary S.
Arthritis & Rheumatology (2024).
10.1002/art.42856
Cite | Source
Joint-specific regulation of homeobox D10 expression in rheumatoid arthritis fibroblast-like synoviocytes (journal article)
Lee, Hyeonjeong | Machado, Camilla R. L. | Hammaker, Deepa | Choi, Eunice | Prideaux, Edward B. | Wang, Wei | Boyle, David L. | Firestein, Gary S.
PLOS ONE, volume 19, issue 6, pages e0304530- (2024).
10.1371/journal.pone.0304530
Cite | Source
Laser Capture Microscopy RNA Sequencing for Topological Mapping of Synovial Pathology During Rheumatoid Arthritis (journal article)
Van Espen, Benjamin | Prideaux, E. Barton | Wilson, Andrew R. | Machado, Camilla R. L. | Sendo, Sho | Parker, James | Seumois, Grégory | Sacchetti, Cristiano | Belongia, Anna C. | Perumal, Narayanan B. | ... | Stanford, Stephanie M.
Arthritis & Rheumatology (2024).
10.1002/art.42853
Cite | Source
What Is Rheumatoid Arthritis? (journal article)
Gravallese, Ellen M. | Firestein, Gary S. | Koscal, Natalie | Ling, Emily | Longo, Dan L. | Messenger, Lori A. | Schubach, Abigail
New England Journal of Medicine, volume 390, issue 13 (2024).
10.1056/NEJMp2310178
Cited by (1) | Cite | Source
The Natural History of Post-Chikungunya Viral Arthritis Disease Activity and T-cell Immunology: A Cohort Study (journal article)
Chang, Aileen Yu-hen | Hernández, Alfonso Sucerquia | Forero-Mejía, Jose | Tritsch, Sarah Renee | Mendoza-Torres, Evelyn | Encinales, Liliana | Bonfanti, Andres Cadena | Proctor, Abigale Marie | Simon, Gary Leonard | Simmens, Samuel Joseph | Firestein, Gary Steven
Journal of Cellular Immunology, volume 6, issue 2, pages 64-75 (2024).
10.33696/immunology.6.191
Cite | Source
Serum reactivity to citrullinated protein/peptide antigens and left ventricular structure and function in the Multi-Ethnic Study of Atherosclerosis (MESA) (journal article)
Hughes-Austin, Jan M. | Katz, Ronit | Majka, Darcy S. | Criqui, Michael H. | Robinson, William H. | Firestein, Gary S. | Hundley, W. Gregory | Ix, Joachim H.
PLOS ONE, volume 18, issue 10, pages e0291967- (2023).
10.1371/journal.pone.0291967
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Fibroblast multiplicity in RA: a synovial state of affairs (journal article)
Machado, Camilla R. L. | Firestein, Gary S.
Nature Reviews Rheumatology, volume 19, issue 10, pages 609-610 (2023).
10.1038/s41584-023-01015-2
Cited by (2) | Cite | Source
POS0017 ACTIVATED B CELLS ARE ENRICHED FOR RANKL AND PROINFLAMMATORY CYTOKINE PRODUCTION PRIOR TO ONSET OF CLINICAL RHEUMATOID ARTHRITIS (conference)
Glass, M. | Pebworth, M. P. | Savage, A. | Gillespie, M. | Dornisch, E. | Moss, N. | Weiss, M. | Skene, P. | Reading, J. | Becker, L. | ... | Torgerson, T.
EULAR 2023 European Congress of Rheumatology, 31 May - 3 June. Milan, Italy (2023)
10.1136/annrheumdis-2023-eular.3378
Cite | Source
Rheumatoid Arthritis — Common Origins, Divergent Mechanisms (journal article)
Gravallese, Ellen M. | Firestein, Gary S.
New England Journal of Medicine, volume 388, issue 6, pages 529-542 (2023).
10.1056/NEJMra2103726
Cited by (155) | Cite | Source
The Evolve to Next-Gen ACT Network: An evolving open-access, real-world data resource primed for real-world evidence research across the Clinical and Translational Science Award Consortium (journal article)
Morrato, Elaine H. | Lennox, Lindsay A. | Dearing, James W. | Coughlan, Anne T. | Gano, Elaina S. | McFadden, Doug | Mora, Nallely | Pincus, Harold Alan | Firestein, Gary S. | Toto, Robert | Reis, Steven E.
Journal of Clinical and Translational Science, volume 7, issue 1 (2023).
10.1017/cts.2023.617
Cited by (1) | Cite | Source
The pathogenesis of rheumatoid arthritis (journal article)
Alivernini, Stefano | Firestein, Gary S. | McInnes, Iain B.
Immunity, volume 55, issue 12, pages 2255-2270 (2022).
10.1016/j.immuni.2022.11.009
Cited by (87) | Cite | Source
Targeting fibroblast-like synoviocytes in rheumatoid arthritis (journal article)
Tsaltskan, Vladislav | Firestein, Gary S.
Current Opinion in Pharmacology, volume 67 (2022).
10.1016/j.coph.2022.102304
Cited by (35) | Cite | Source
Systems-biology analysis of rheumatoid arthritis fibroblast-like synoviocytes implicates cell line-specific transcription factor function (journal article)
Ainsworth, Richard I. | Hammaker, Deepa | Nygaard, Gyrid | Ansalone, Cecilia | Machado, Camilla | Zhang, Kai | Zheng, Lina | Carrillo, Lucy | Wildberg, Andre | Kuhs, Amanda | ... | Wang, Wei
Nature Communications, volume 13, issue 1 (2022).
10.1038/s41467-022-33785-w
Cited by (16) | Cite | Source
Mechanism‐driven strategies for prevention of rheumatoid arthritis (journal article)
Holers, V. Michael | Kuhn, Kristine A. | Demoruelle, M. Kristen | Norris, Jill M. | Firestein, Gary S. | James, Eddie A. | Robinson, William H. | Buckner, Jane H. | Deane, Kevin D.
Rheumatology & Autoimmunity, volume 2, issue 3, pages 109-119 (2022).
10.1002/rai2.12043
Cited by (15) | Cite | Source
Improving Transcriptome Fidelity Following Synovial Tissue Disaggregation (journal article)
Boyle, David L. | Prideaux, Edward B. | Hillman, Joshua | Wang, Wei | Firestein, Gary S.
Frontiers in Medicine, volume 9 (2022).
10.3389/fmed.2022.919748
Cited by (1) | Cite | Source
Comparison of Web‐Based Advertising and a Social Media Platform as Recruitment Tools for Underserved and Hard‐to‐Reach Populations in Rheumatology Clinical Research (journal article)
Tsaltskan, Vladislav | Nguyen, Katherine | Eaglin, Christina | Holers, V. Michael | Deane, Kevin D. | Firestein, Gary S.
ACR Open Rheumatology, volume 4, issue 7, pages 623-630 (2022).
10.1002/acr2.11448
Cited by (5) | Cite | Source
Epigenetic Regulation of Nutrient Transporters in Rheumatoid Arthritis Fibroblast‐like Synoviocytes (journal article)
Torres, Alyssa | Pedersen, Brian | Cobo, Isidoro | Ai, Rizi | Coras, Roxana | Murillo‐Saich, Jessica | Nygaard, Gyrid | Sanchez‐Lopez, Elsa | Murphy, Anne | Wang, Wei | ... | Guma, Monica
Arthritis & Rheumatology, volume 74, issue 7, pages 1159-1171 (2022).
10.1002/art.42077
Cited by (13) | Cite | Source
Crosstalk between CD4 T cells and synovial fibroblasts from human arthritic joints promotes hyaluronan-dependent leukocyte adhesion and inflammatory cytokine expression in vitro (journal article)
Kang, Inkyung | Hundhausen, Christian | Evanko, Stephen P. | Malapati, Prasanthi | Workman, Gail | Chan, Christina K. | Rims, Cliff | Firestein, Gary S. | Boyle, David L. | MacDonald, Kevin M. | ... | Wight, Thomas N.
Matrix Biology Plus, volume 14 (2022).
10.1016/j.mbplus.2022.100110
Cited by (1) | Cite | Source
Caspase‐8 Variant G Regulates Rheumatoid Arthritis Fibroblast‐Like Synoviocyte Aggressive Behavior (journal article)
Ansalone, Cecilia | Ainsworth, Richard I. | Nygaard, Gyrid | Ai, Rizi | Prideaux, Edward B. | Hammaker, Deepa | Perumal, Narayanan B. | Weichert, Ken | Tung, Frances | Kodandapani, Lalitha | ... | Firestein, Gary S.
ACR Open Rheumatology, volume 4, issue 4, pages 288-299 (2022).
10.1002/acr2.11384
Cited by (4) | Cite | Source