Barry L. Stoddard

ScholarGPS® ID: 34565240591764

Affiliation
Fred Hutchinson Cancer Research Center, United States
Affiliation History

Field
Life Sciences
Discipline
Molecular and Cell Biology
Top Specialties
DNA | Nucleic Acid | Enzyme | Crystal Structure | Crystallography | X-ray | DNA Profiling | Yeast | Factor VIII | Structural Biology | Bacteria | Restriction Enzyme | Protein Engineering | Pseudomonas Putida | Superoxide Dismutase
Metrics Summary
Publication Count
202
Predicted Citations
23,892
Predicted h-index
81
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1 (journal article)
Grünberg, Sebastian | Doyle, Lindsey A. | Wolf, Eric J. | Dai, Nan | Corrêa, Ivan R. | Yigit, Erbay | Stoddard, Barry L.
PLOS ONE, volume 18, issue 11, pages e0291267- (2023).
10.1371/journal.pone.0291267
Cite | Source
De novo design of knotted tandem repeat proteins (journal article)
Doyle, Lindsey A. | Takushi, Brittany | Kibler, Ryan D. | Milles, Lukas F. | Orozco, Carolina T. | Jones, Jonathan D. | Jackson, Sophie E. | Stoddard, Barry L. | Bradley, Philip
Nature Communications, volume 14, issue 1 (2023).
10.1038/s41467-023-42388-y
Cited by (7) | Cite | Source
Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI (journal article)
Kennedy, Madison A | Hosford, Christopher J | Azumaya, Caleigh M | Luyten, Yvette A | Chen, Minyong | Morgan, Richard D | Stoddard, Barry L
Nucleic Acids Research, volume 51, issue 9, pages 4467-4487 (2023).
10.1093/nar/gkad228
Cited by (2) | Cite | Source
Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor (journal article)
Shen, Betty W | Doyle, Lindsey A | Werther, Rachel | Westburg, Abigail A | Bies, Daniel P | Walter, Stephanie I | Luyten, Yvette A | Morgan, Richard D | Stoddard, Barry L | Kaiser, Brett K
Nucleic Acids Research, volume 51, issue 8, pages 3513-3528 (2023).
10.1093/nar/gkad083
Cited by (7) | Cite | Source
De novo design of protein homodimers containing tunable symmetric protein pockets (journal article)
Hicks, Derrick R. | Kennedy, Madison A. | Thompson, Kirsten A. | DeWitt, Michelle | Coventry, Brian | Kang, Alex | Bera, Asim K. | Brunette, T. J. | Sankaran, Banumathi | Stoddard, Barry | Baker, David
Proceedings of the National Academy of Sciences, volume 119, issue 30 (2022).
10.1073/pnas.2113400119
Cited by (8) | Cite | Source
Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system (journal article)
Luyten, Yvette A | Hausman, Deanna E | Young, Juliana C | Doyle, Lindsey A | Higashi, Kerilyn M | Ubilla-Rodriguez, Natalia C | Lambert, Abigail R | Arroyo, Corina S | Forsberg, Kevin J | Morgan, Richard D | ... | Kaiser, Brett K
Nucleic Acids Research, volume 50, issue 9, pages 5171-5190 (2022).
10.1093/nar/gkac311
Cited by (15) | Cite | Source
Design of functionalised circular tandem repeat proteins with longer repeat topologies and enhanced subunit contact surfaces (journal article)
Hallinan, Jazmine P. | Doyle, Lindsey A. | Shen, Betty W. | Gewe, Mesfin M. | Takushi, Brittany | Kennedy, Madison A. | Friend, Della | Roberts, James M. | Bradley, Philip | Stoddard, Barry L.
Communications Biology, volume 4, issue 1 (2021).
10.1038/s42003-021-02766-y
Cited by (6) | Cite | Source
The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity (journal article)
Forsberg, Kevin J. | Schmidtke, Danica T. | Werther, Rachel | Uribe, Ruben V. | Hausman, Deanna | Sommer, Morten O. A. | Stoddard, Barry L. | Kaiser, Brett K. | Malik, Harmit S.
PLOS Biology, volume 19, issue 10, pages e3001428- (2021).
10.1371/journal.pbio.3001428
Cited by (14) | Cite | Source
Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM (journal article)
Shen, Betty W. | Quispe, Joel D. | Luyten, Yvette | McGough, Benjamin E. | Morgan, Richard D. | Stoddard, Barry L.
Structure, volume 29, issue 6, pages 521-530.e5 (2021).
10.1016/j.str.2021.03.012
Cited by (5) | Cite | Source
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins (journal article)
Klima, Jason C. | Doyle, Lindsey A. | Lee, Justin Daho | Rappleye, Michael | Gagnon, Lauren A. | Lee, Min Yen | Barros, Emilia P. | Vorobieva, Anastassia A. | Dou, Jiayi | Bremner, Samantha | ... | Baker, David
Nature Communications, volume 12, issue 1 (2021).
10.1038/s41467-020-18911-w
Cited by (23) | Cite | Source
Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition (journal article)
Lambert, Abigail R. | Hallinan, Jazmine P. | Werther, Rachel | Głów, Dawid | Stoddard, Barry L.
Structure, volume 28, issue 7, pages 760-775.e8 (2020).
10.1016/j.str.2020.04.009
Cited by (9) | Cite | Source
Compositions and methods for the treatment of hemoglobinopathies (patent)
Takeuchi, Ryo | Groudine, Mark T | Stoddard, Barry L. | Bender, Michael A
Patent Number: 10619140 (2020)
Cited by (1) | Cite | Source
Structural and Functional Characterization of the Integrase HK022 (journal article)
Kennedy, Madison Arza | Stoddard, Barry
The FASEB Journal, volume 34, issue S1, pages 1-1 (2020).
10.1096/fasebj.2020.34.s1.00076
Cite | Source
Characterizing the Function of Anti‐CRISPR protein AcrIIA11 (journal article)
del Banco, Serena Bautista | Kaiser, Brett | Forsberg, Kevin | Malik, Harmit | Stoddard, Barry
The FASEB Journal, volume 34, issue S1, pages 1-1 (2020).
10.1096/fasebj.2020.34.s1.09175
Cited by (1) | Cite | Source
Engineering and functionalization of large circular tandem repeat protein nanoparticles (journal article)
Correnti, Colin E. | Hallinan, Jazmine P. | Doyle, Lindsey A. | Ruff, Raymond O. | Jaeger-Ruckstuhl, Carla A. | Xu, Yuexin | Shen, Betty W. | Qu, Amanda | Polkinghorn, Caley | Friend, Della J. | ... | Bradley, Philip
Nature Structural & Molecular Biology, volume 27, issue 4, pages 342-350 (2020).
10.1038/s41594-020-0397-5
Cited by (18) | Cite | Source
Circular tandem repeat proteins (patent)
Bradley, Philip | Stoddard, Barry L.
Patent Number: 10597466 (2020)
Cite | Source
Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome (journal article)
Forsberg, Kevin J | Bhatt, Ishan V | Schmidtke, Danica T | Javanmardi, Kamyab | Dillard, Kaylee E | Stoddard, Barry L | Finkelstein, Ilya J | Kaiser, Brett K | Malik, Harmit S
eLife, volume 8 (2019).
10.7554/eLife.46540
Cited by (50) | Cite | Source
Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI (journal article)
Shen, Betty W | Doyle, Lindsey | Bradley, Phil | Heiter, Daniel F | Lunnen, Keith D | Wilson, Geoffrey G | Stoddard, Barry L
Nucleic Acids Research, volume 47, issue 1, pages 450-467 (2019).
10.1093/nar/gky1059
Cited by (3) | Cite | Source
Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI (journal article)
Bradley, Philip | Doyl, L. | Heiter, Daniel F. | Lunnen, Keith D. | Shen, Betty W. | Stoddard, Barry L. | Wilson, Geoffrey G.
Nucleic Acids Research (2018).
10.2210/pdb6maf/pdb
Cited by (1) | Cite | Source
Unintended specificity of an engineered ligand-binding protein facilitated by unpredicted plasticity of the protein fold (journal article)
Day, Austin L | Greisen, Per | Doyle, Lindsey | Schena, Alberto | Stella, Nephi | Johnsson, Kai | Baker, David | Stoddard, Barry
Protein Engineering, Design and Selection, volume 31, issue 10, pages 375-387 (2018).
10.1093/protein/gzy031
Cited by (6) | Cite | Source