Daniel J. Parks

ScholarGPS® ID: 34236912894994

Affiliation
Johnson & Johnson, New Brunswick, New Jersey, United States
Affiliation History

Field
Physical Sciences and Mathematics
Discipline
Chemistry
Top Specialties
Medicinal Chemistry | Biosynthesis | Chemical Synthesis
Metrics Summary
Publication Count
22
Predicted Citations
5,503
Predicted h-index
22
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors (journal article)
Meegalla, Sanath K. | Huang, Hui | Illig, Carl R. | Parks, Daniel J. | Chen, Jinsheng | Lee, Yu-Kai | Wilson, Kenneth J. | Patel, Sharmila K. | Cheung, Wing S. | Lu, Tianbao | ... | Player, Mark R.
Bioorganic & Medicinal Chemistry Letters, volume 26, issue 17, pages 4216-4222 (2016).
10.1016/j.bmcl.2016.07.054
Cited by (12) | Cite | Source
Discovery of vinylcycloalkyl-substituted benzimidazole TRPM8 antagonists effective in the treatment of cold allodynia (journal article)
Calvo, Raul R. | Meegalla, Sanath K. | Parks, Daniel J. | Parsons, William H. | Ballentine, Shelley K. | Lubin, Mary Lou | Schneider, Craig | Colburn, Raymond W. | Flores, Christopher M. | Player, Mark R.
Bioorganic & Medicinal Chemistry Letters, volume 22, issue 5, pages 1903-1907 (2012).
10.1016/j.bmcl.2012.01.060
Cited by (34) | Cite | Source
Design and Optimization of Benzimidazole-Containing Transient Receptor Potential Melastatin 8 (TRPM8) Antagonists (journal article)
Parks, Daniel J. | Parsons, William H. | Colburn, Raymond W. | Meegalla, Sanath K. | Ballentine, Shelley K. | Illig, Carl R. | Qin, Ning | Liu, Yi | Hutchinson, Tasha L. | Lubin, Mary Lou | ... | Player, Mark R.
Journal of Medicinal Chemistry, volume 54, issue 1, pages 233-247 (2011).
10.1021/jm101075v
Cited by (59) | Cite | Source
7-Fluoroindazoles as Potent and Selective Inhibitors of Factor Xa (journal article)
Lee, Yu-Kai | Parks, Daniel J. | Lu, Tianbao | Thieu, Tho V. | Markotan, Thomas | Pan, Wenxi | McComsey, David F. | Milkiewicz, Karen L. | Crysler, Carl S. | Ninan, Nisha | ... | Player, Mark R.
Journal of Medicinal Chemistry, volume 51, issue 2, pages 282-297 (2008).
10.1021/jm701217r
Cited by (52) | Cite | Source
Enhanced pharmacokinetic properties of 1,4-benzodiazepine-2,5-dione antagonists of the HDM2-p53 protein–protein interaction through structure-based drug design (journal article)
Parks, Daniel J. | LaFrance, Louis V. | Calvo, Raul R. | Milkiewicz, Karen L. | José Marugán, Juan | Raboisson, Pierre | Schubert, Carsten | Koblish, Holly K. | Zhao, Shuyuan | Franks, Carol F. | ... | Lu, Tianbao
Bioorganic & Medicinal Chemistry Letters, volume 16, issue 12, pages 3310-3314 (2006).
10.1016/j.bmcl.2006.03.055
Cited by (70) | Cite | Source
Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo (journal article)
Koblish, Holly K. | Zhao, Shuyuan | Franks, Carol F. | Donatelli, Robert R. | Tominovich, Rose M. | LaFrance, Louis V. | Leonard, Kristi A. | Gushue, Joan M. | Parks, Daniel J. | Calvo, Raul R. | ... | Maroney, Anna C.
Molecular Cancer Therapeutics, volume 5, issue 1, pages 160-169 (2006).
10.1158/1535-7163.MCT-05-0199
Cited by (145) | Cite | Source | Open Access
Structure-based design, synthesis, and biological evaluation of novel 1,4-diazepines as HDM2 antagonists (journal article)
Raboisson, Pierre | Marugán, Juan José | Schubert, Carsten | Koblish, Holly K. | Lu, Tianbao | Zhao, Shuyuan | Player, Mark R. | Maroney, Anna C. | Reed, Rolanda L. | Huebert, Norman D. | ... | Cummings, Maxwell D.
Bioorganic & Medicinal Chemistry Letters, volume 15, issue 7, pages 1857-1861 (2005).
10.1016/j.bmcl.2005.02.018
Cited by (49) | Cite | Source
1,4-Benzodiazepine-2,5-diones as small molecule antagonists of the HDM2–p53 interaction: discovery and SAR (journal article)
Parks, Daniel J. | LaFrance, Louis V. | Calvo, Raul R. | Milkiewicz, Karen L. | Gupta, Varsha | Lattanze, Jennifer | Ramachandren, Kannan | Carver, Theodore E. | Petrella, Eugene C. | Cummings, Maxwell D. | ... | Lu, Tianbao
Bioorganic & Medicinal Chemistry Letters, volume 15, issue 3, pages 765-770 (2005).
10.1016/j.bmcl.2004.11.009
Cited by (156) | Cite | Source
Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells (journal article)
Grasberger, Bruce L. | Lu, Tianbao | Schubert, Carsten | Parks, Daniel J. | Carver, Theodore E. | Koblish, Holly K. | Cummings, Maxwell D. | LaFrance, Louis V. | Milkiewicz, Karen L. | Calvo, Raul R. | ... | Bone, Roger F.
Journal of Medicinal Chemistry, volume 48, issue 4, pages 909-912 (2005).
10.1021/jm049137g
Cited by (393) | Cite | Source
ChemInform Abstract: The Synthesis of Ethanolamine Libraries from Olefin Scaffolds. (journal article)
Organ, Michael G. | Kaldor, Stephen W. | Dixon, Craig E. | Parks, Daniel J. | Singh, Upinder | Lavorato, David J. | Isbester, Paul K. | Siegel, Miles G.
ChemInform, volume 32, issue 4 (2001).
10.1002/chin.200104105
Cite | Source
The synthesis of ethanolamine libraries from olefin scaffolds (journal article)
Organ, Michael G | Kaldor, Stephen W | Dixon, Craig E | Parks, Daniel J | Singh, Upinder | Lavorato, David J | Isbester, Paul K | Siegel*, Miles G
Tetrahedron Letters, volume 41, issue 44, pages 8407-8411 (2000).
10.1016/S0040-4039(00)01503-3
Cited by (5) | Cite | Source
Studies on the Mechanism of B(C6 F5 )3 -Catalyzed Hydrosilation of Carbonyl Functions (journal article)
Parks, Daniel J. | Blackwell, James M. | Piers, Warren E.
The Journal of Organic Chemistry, volume 65, issue 10, pages 3090-3098 (2000).
10.1021/jo991828a
Cited by (655) | Cite | Source
ChemInform Abstract: Hydroboration of Vinyl Silanes with Bis-(pentafluorophenyl)borane: Ground State β-Silicon Effects. (journal article)
Parks, Daniel J. | Piers, Warren E.
ChemInform, volume 30, issue 18, pages no-no (1999).
10.1002/chin.199918158
Cite | Source
Synthesis, Properties, and Hydroboration Activity of the Highly Electrophilic Borane Bis(pentafluorophenyl)borane, HB(C6 F5 )21 (journal article)
Parks, Daniel J. | Piers, Warren E. | Yap, Glenn P. A.
Organometallics, volume 17, issue 25, pages 5492-5503 (1998).
10.1021/om980673e
Cited by (497) | Cite | Source
Hydroboration of vinyl silanes with bis-(pentafluorophenyl)borane: Ground state β-silicon effects (journal article)
Parks, Daniel J. | Piers, Warren E.
Tetrahedron, volume 54, issue 51, pages 15469-15488 (1998).
10.1016/S0040-4020(98)01008-4
Cited by (72) | Cite | Source
Synthesis and Solution and Solid-State Structures of Tris(pentafluorophenyl)borane Adducts of PhC(O)X (X = H, Me, OEt, NPr2 ) (journal article)
Parks, Daniel J. | Piers, Warren E. | Parvez, Masood | Atencio, Reinaldo | Zaworotko, Michael J.
Organometallics, volume 17, issue 7, pages 1369-1377 (1998).
10.1021/om9710327
Cited by (163) | Cite | Source
Tris(pentafluorophenyl)boron-Catalyzed Hydrosilation of Aromatic Aldehydes, Ketones, and Esters (journal article)
Parks, Daniel J. | Piers, Warren E.
Journal of the American Chemical Society, volume 118, issue 39, pages 9440-9441 (1996).
10.1021/ja961536g
Cited by (695) | Cite | Source
Competing Pathways in the Reaction of Bis(pentafluorophenyl)borane with Bis(η5 ‐cyclopentadienyl)dimethylzirconium: Methane Elimination versus Methyl–Hydride Exchange and an Example of Pentacoordinate Carbon (journal article)
von H. Spence, Rupert E. | Parks, Daniel J. | Piers, Warren E. | MacDonald, Mary‐Anne | Zaworotko, Michael J. | Rettig, Steven J.
Angewandte Chemie International Edition in English, volume 34, issue 11, pages 1230-1233 (1995).
10.1002/anie.199512301
Cited by (94) | Cite | Source
Konkurrierende Reaktionswege bei der Reaktion von Bis(pentafluorphenyl)boran mit Bis(η5 ‐cyclopentadienyl)dimethylzirconium: Methan‐Eliminierung oder Methyl‐Hydrid‐Austausch und ein Beispiel für fünffach koordinierten Kohlenstoff (journal article)
von H. Spence, Rupert E. | Parks, Daniel J. | Piers, Warren E. | MacDonald, Mary‐Anne | Zaworotko, Michael J. | Rettig, Steven J.
Angewandte Chemie, volume 107, issue 11, pages 1337-1340 (1995).
10.1002/ange.19951071118
Cited by (35) | Cite | Source
Bis(pentafluorophenyl)borane: Synthesis, Properties, and Hydroboration Chemistry of a Highly Electrophilic Borane Reagent (journal article)
Parks, Daniel J. | von H. Spence, Rupert E. | Piers, Warren E.
Angewandte Chemie International Edition in English, volume 34, issue 7, pages 809-811 (1995).
10.1002/anie.199508091
Cited by (373) | Cite | Source