Chris Tyler-Smith

ScholarGPS® ID: 32722048517316

Affiliation

Wellcome Sanger Institute, Hinxton, United Kingdom

Affiliation History

Field

Life Sciences

Discipline

Biochemistry

Top Specialties

Metrics Summary

Publication Count

323

Predicted Citations

35,107

Predicted h-index

102

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling (journal article) Pedrazza, Leonardo \| Martinez-Martinez, Arturo \| Sánchez-de-Diego, Cristina \| Valer, José Antonio \| Pimenta-Lopes, Carolina \| Sala-Gaston, Joan \| Szpak, Michal \| Tyler-Smith, Chris \| Ventura, Francesc \| Rosa, Jose Luis Cell Death & Disease, volume 14, issue 1 (2023). 10.1038/s41419-023-05549-x Cited by (2) \| Cite \| Source
Sequence analyses of Malaysian Indigenous communities reveal historical admixture between Hoabinhian hunter-gatherers and Neolithic farmers (journal article) Aghakhanian, Farhang \| Hoh, Boon-Peng \| Yew, Chee-Wei \| Kumar Subbiah, Vijay \| Xue, Yali \| Tyler-Smith, Chris \| Ayub, Qasim \| Phipps, Maude E. Scientific Reports, volume 12, issue 1 (2022). 10.1038/s41598-022-17884-8 Cited by (1) \| Cite \| Source
A Positively Selected MAGEE2 LoF Allele Is Associated with Sexual Dimorphism in Human Brain Size and Shows Similar Phenotypes in Magee2 Null Mice (journal article) Szpak, Michał \| Collins, Stephan C \| Li, Yan \| Liu, Xiao \| Ayub, Qasim \| Fischer, Marie-Christine \| Vancollie, Valerie E \| Lelliott, Christopher J \| Xue, Yali \| Yalcin, Binnaz \| ... \| Tyler-Smith, Chris Molecular Biology and Evolution, volume 38, issue 12, pages 5655-5663 (2021). 10.1093/molbev/msab243 Cited by (1) \| Cite \| Source
The genomic history of the Middle East (journal article) Almarri, Mohamed A. \| Haber, Marc \| Lootah, Reem A. \| Hallast, Pille \| Al Turki, Saeed \| Martin, Hilary C. \| Xue, Yali \| Tyler-Smith, Chris Cell, volume 184, issue 18, pages 4612-4625.e14 (2021). 10.1016/j.cell.2021.07.013 Cited by (23) \| Cite \| Source
The landscape of autosomal-recessive pathogenic variants in European populations reveals phenotype-specific effects (journal article) Fridman, Hila \| Yntema, Helger G. \| Mägi, Reedik \| Andreson, Reidar \| Metspalu, Andres \| Mezzavilla, Massimo \| Tyler-Smith, Chris \| Xue, Yali \| Carmi, Shai \| Levy-Lahad, Ephrat \| ... \| Brunner, Han G. The American Journal of Human Genetics, volume 108, issue 4, pages 608-619 (2021). 10.1016/j.ajhg.2021.03.004 Cited by (35) \| Cite \| Source
A common 1.6 mb Y-chromosomal inversion predisposes to subsequent deletions and severe spermatogenic failure in humans (journal article) Hallast, Pille \| Kibena, Laura \| Punab, Margus \| Arciero, Elena \| Rootsi, Siiri \| Grigorova, Marina \| Flores, Rodrigo \| Jobling, Mark A \| Poolamets, Olev \| Pomm, Kristjan \| ... \| Laan, Maris eLife, volume 10 (2021). 10.7554/eLife.65420 Cited by (6) \| Cite \| Source
Subdividing Y-chromosome haplogroup R1a1 reveals Norse Viking dispersal lineages in Britain (journal article) Lall, Gurdeep Matharu \| Larmuseau, Maarten H. D. \| Wetton, Jon H. \| Batini, Chiara \| Hallast, Pille \| Huszar, Tunde I. \| Zadik, Daniel \| Aase, Sigurd \| Baker, Tina \| Balaresque, Patricia \| ... \| Jobling, Mark A. European Journal of Human Genetics, volume 29, issue 3, pages 512-523 (2021). 10.1038/s41431-020-00747-z Cited by (6) \| Cite \| Source
A Southeast Asian origin for present-day non-African human Y chromosomes (journal article) Hallast, Pille \| Agdzhoyan, Anastasia \| Balanovsky, Oleg \| Xue, Yali \| Tyler-Smith, Chris Human Genetics, volume 140, issue 2, pages 299-307 (2021). 10.1007/s00439-020-02204-9 Cited by (12) \| Cite \| Source
Positive selection in admixed populations from Ethiopia (journal article) Walsh, Sandra \| Pagani, Luca \| Xue, Yali \| Laayouni, Hafid \| Tyler-Smith, Chris \| Bertranpetit, Jaume BMC Genetics, volume 21, issue S1 (2020). 10.1186/s12863-020-00908-5 Cited by (5) \| Cite \| Source
A Genetic History of the Near East from an aDNA Time Course Sampling Eight Points in the Past 4,000 Years (journal article) Haber, Marc \| Nassar, Joyce \| Almarri, Mohamed A. \| Saupe, Tina \| Saag, Lehti \| Griffith, Samuel J. \| Doumet-Serhal, Claude \| Chanteau, Julien \| Saghieh-Beydoun, Muntaha \| Xue, Yali \| ... \| Tyler-Smith, Chris The American Journal of Human Genetics, volume 107, issue 1, pages 149-157 (2020). 10.1016/j.ajhg.2020.05.008 Cited by (20) \| Cite \| Source
Population Structure, Stratification, and Introgression of Human Structural Variation (journal article) Almarri, Mohamed A. \| Bergström, Anders \| Prado-Martinez, Javier \| Yang, Fengtang \| Fu, Beiyuan \| Dunham, Alistair S. \| Chen, Yuan \| Hurles, Matthew E. \| Tyler-Smith, Chris \| Xue, Yali Cell, volume 182, issue 1, pages 189-199.e15 (2020). 10.1016/j.cell.2020.05.024 Cited by (50) \| Cite \| Source
Insights into human genetic variation and population history from 929 diverse genomes (journal article) Bergström, Anders \| McCarthy, Shane A. \| Hui, Ruoyun \| Almarri, Mohamed A. \| Ayub, Qasim \| Danecek, Petr \| Chen, Yuan \| Felkel, Sabine \| Hallast, Pille \| Kamm, Jack \| ... \| Tyler-Smith, Chris Science, volume 367, issue 6484 (2020). 10.1126/science.aay5012 Cited by (393) \| Cite \| Source
Birth, expansion, and death of VCY-containing palindromes on the human Y chromosome (journal article) Shi, Wentao \| Massaia, Andrea \| Louzada, Sandra \| Handsaker, Juliet \| Chow, William \| McCarthy, Shane \| Collins, Joanna \| Hallast, Pille \| Howe, Kerstin \| Church, Deanna M. \| ... \| Tyler-Smith, Chris Genome Biology, volume 20, issue 1 (2019). 10.1186/s13059-019-1816-y Cited by (9) \| Cite \| Source
Evolutionary and functional analysis of RBMY1 gene copy number variation on the human Y chromosome (journal article) Shi, Wentao \| Louzada, Sandra \| Grigorova, Marina \| Massaia, Andrea \| Arciero, Elena \| Kibena, Laura \| Ge, Xiangyu Jack \| Chen, Yuan \| Ayub, Qasim \| Poolamets, Olev \| ... \| Xue, Yali Human Molecular Genetics, volume 28, issue 16, pages 2785-2798 (2019). 10.1093/hmg/ddz101 Cited by (5) \| Cite \| Source
A Rare Deep-Rooting D0 African Y-Chromosomal Haplogroup and Its Implications for the Expansion of Modern Humans Out of Africa (journal article) Haber, Marc \| Jones, Abigail L \| Connell, Bruce A \| Arciero, Elena \| Yang, Huanming \| Thomas, Mark G \| Xue, Yali \| Tyler-Smith, Chris Genetics, volume 212, issue 4, pages 1421-1428 (2019). 10.1534/genetics.119.302368 Cited by (31) \| Cite \| Source
A Transient Pulse of Genetic Admixture from the Crusaders in the Near East Identified from Ancient Genome Sequences (journal article) Haber, Marc \| Doumet-Serhal, Claude \| Scheib, Christiana L. \| Xue, Yali \| Mikulski, Richard \| Martiniano, Rui \| Fischer-Genz, Bettina \| Schutkowski, Holger \| Kivisild, Toomas \| Tyler-Smith, Chris The American Journal of Human Genetics, volume 104, issue 5, pages 977-984 (2019). 10.1016/j.ajhg.2019.03.015 Cited by (26) \| Cite \| Source
Positive selection in Europeans and East-Asians at the ABCA12 gene (journal article) Sirica, Roberto \| Buonaiuto, Marianna \| Petrella, Valeria \| Sticco, Lucia \| Tramontano, Donatella \| Antonini, Dario \| Missero, Caterina \| Guardiola, Ombretta \| Andolfi, Gennaro \| Kumar, Heerman \| ... \| Colonna, Vincenza Scientific Reports, volume 9, issue 1 (2019). 10.1038/s41598-019-40360-9 Cited by (1) \| Cite \| Source
Y Chromosome Sequences Reveal a Short Beringian Standstill, Rapid Expansion, and early Population structure of Native American Founders (journal article) Pinotti, Thomaz \| Bergström, Anders \| Geppert, Maria \| Bawn, Matt \| Ohasi, Dominique \| Shi, Wentao \| Lacerda, Daniela R. \| Solli, Arne \| Norstedt, Jakob \| Reed, Kate \| ... \| Tyler-Smith, Chris Current Biology, volume 29, issue 1, pages 149-157.e3 (2019). 10.1016/j.cub.2018.11.029 Cited by (73) \| Cite \| Source
FineMAV: prioritizing candidate genetic variants driving local adaptations in human populations (journal article) Szpak, Michał \| Mezzavilla, Massimo \| Ayub, Qasim \| Chen, Yuan \| Xue, Yali \| Tyler-Smith, Chris Genome Biology, volume 19, issue 1 (2018). 10.1186/s13059-017-1380-2 Cited by (17) \| Cite \| Source \| Open Access
Positive selection in Europeans and East-Asians at the ABCA12 gene (journal article) Sirica, Roberto \| Buonaiuto, Marianna \| Petrella, Valeria \| Sticco, Lucia \| Tramontano, Donatella \| Antonini, Dario \| Missero, Caterina \| Guardiola, Ombretta \| Andolfi, Gennaro \| Kumar, Heerman \| ... \| Colonna, Vincenza bioRxiv (2018). 10.1101/392811 Cite \| Source \| Open Access