Judith A. Steen

ScholarGPS® ID: 32585413563065

Affiliation

Boston Children's Hospital, Boston, United States

Affiliation History

Field

Life Sciences

Discipline

Neurosciences

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

7,020

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Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
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NIH/NSF

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Longitudinal plasma proteomic analysis of 1117 hospitalized patients with COVID-19 identifies features associated with severity and outcomes (journal article) Viode, Arthur \| Smolen, Kinga K. \| van Zalm, Patrick \| Stevenson, David \| Jha, Meenakshi \| Parker, Kenneth \| Levy, Ofer \| Steen, Judith A. \| Steen, Hanno Science Advances, volume 10, issue 21 (2024). 10.1126/sciadv.adl5762 Cited by (1) \| Cite \| Source
Quantitative profiling of posttranslational modifications of pathological tau via sarkosyl fractionation and mass spectrometry (journal article) Wenger, Kathrin \| Viode, Arthur \| Kumar, Mukesh \| Steen, Hanno \| Steen, Judith A. Nature Protocols, volume 19, issue 4, pages 1235-1251 (2024). 10.1038/s41596-023-00939-z Cite \| Source
Alzheimer proteopathic tau seeds are biochemically a forme fruste of mature paired helical filaments (journal article) Kumar, Mukesh \| Quittot, Noé \| Dujardin, Simon \| Schlaffner, Christoph N \| Viode, Arthur \| Wiedmer, Anne \| Beerepoot, Pieter \| Chun, Joshua E \| Glynn, Calina \| Fernandes, Analiese R \| ... \| Hyman, Bradley T Brain, volume 147, issue 2, pages 637-648 (2024). 10.1093/brain/awad378 Cite \| Source
Meta-analysis of published cerebrospinal fluid proteomics data identifies and validates metabolic enzyme panel as Alzheimer’s disease biomarkers (journal article) van Zalm, Patrick W. \| Ahmed, Saima \| Fatou, Benoit \| Schreiber, Rudy \| Barnaby, Omar \| Boxer, Adam \| Zetterberg, Henrik \| Steen, Judith A. \| Steen, Hanno Cell Reports Medicine, volume 4, issue 4, pages 101005- (2023). 10.1016/j.xcrm.2023.101005 Cited by (2) \| Cite \| Source
A simple, time- and cost-effective, high-throughput depletion strategy for deep plasma proteomics (journal article) Viode, Arthur \| van Zalm, Patrick \| Smolen, Kinga K. \| Fatou, Benoit \| Stevenson, David \| Jha, Meenakshi \| Levy, Ofer \| Steen, Judith \| Steen, Hanno Science Advances, volume 9, issue 13 (2023). 10.1126/sciadv.adf9717 Cited by (15) \| Cite \| Source
Common mouse models of tauopathy reflect early but not late human disease (journal article) Wenger, Kathrin \| Viode, Arthur \| Schlaffner, Christoph N. \| van Zalm, Patrick \| Cheng, Long \| Dellovade, Tammy \| Langlois, Xavier \| Bannon, Anthony \| Chang, Rui \| Connors, Theresa R. \| ... \| Steen, Judith A. Molecular Neurodegeneration, volume 18, issue 1 (2023). 10.1186/s13024-023-00601-y Cited by (12) \| Cite \| Source
Polyubiquitination of Tau Increases Across Braak Stages in Alzheimer’s Disease (journal article) Lee, Yoo Bin \| Kramer, Jack \| Oh, Ian \| Li, Song Hua \| Piergies, Antonia M. H. \| Xue, Jie \| Kumar, Mukesh \| Spina, Salvatore \| Steen, Judith A \| Grinberg, Lea Tenenholz Alzheimer's & Dementia, volume 18, issue S3 (2022). 10.1002/alz.066600 Cite \| Source
Using CSF Proteomics to Investigate Herpesvirus Infections of the Central Nervous System (journal article) Ahmed, Saima \| van Zalm, Patrick \| Rudmann, Emily A. \| Leone, Michael \| Keller, Kiana \| Branda, John A. \| Steen, Judith \| Mukerji, Shibani S. \| Steen, Hanno Viruses, volume 14, issue 12, pages 2757- (2022). 10.3390/v14122757 Cited by (2) \| Cite \| Source
A Parallelization Strategy for the Time Efficient Analysis of Thousands of LC/MS Runs in High-Performance Computing Environment (journal article) van Zalm, Patrick \| Viodé, Arthur \| Smolen, Kinga \| Fatou, Benoit \| Hayati, Arash Nemati \| Schlaffner, Christoph N. \| Levy, Ofer \| Steen, Judith \| Steen, Hanno Journal of Proteome Research, volume 21, issue 11, pages 2810-2814 (2022). 10.1021/acs.jproteome.2c00278 Cited by (5) \| Cite \| Source
Using plasma proteomics to investigate viral infections of the central nervous system including patients with HIV-associated neurocognitive disorders (journal article) Ahmed, Saima \| Viode, Arthur \| van Zalm, Patrick \| Steen, Judith \| Mukerji, Shibani S. \| Steen, Hanno Journal of NeuroVirology, volume 28, issue 3, pages 341-354 (2022). 10.1007/s13365-022-01077-0 Cited by (2) \| Cite \| Source
multiFLEX-LF: A Computational Approach to Quantify the Modification Stoichiometries in Label-Free Proteomics Data Sets (journal article) Hiort, Pauline \| Schlaffner, Christoph N. \| Steen, Judith A. \| Renard, Bernhard Y. \| Steen, Hanno Journal of Proteome Research, volume 21, issue 4, pages 899-909 (2022). 10.1021/acs.jproteome.1c00669 Cited by (1) \| Cite \| Source
FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply (journal article) Basu, Himanish \| Pekkurnaz, Gulcin \| Falk, Jill \| Wei, Wei \| Chin, Morven \| Steen, Judith \| Schwarz, Thomas L. Journal of Cell Biology, volume 220, issue 10 (2021). 10.1083/jcb.201912077 Cited by (33) \| Cite \| Source
Phosphorylation‐dependent control of Activity‐regulated cytoskeleton‐associated protein (Arc) protein by TNIK (journal article) Walczyk‐Mooradally, Alicyia \| Holborn, Jennifer \| Singh, Karamjeet \| Tyler, Marshall \| Patnaik, Debasis \| Wesseling, Hendrik \| Brandon, Nicholas J. \| Steen, Judith \| Graether, Steffen P. \| Haggarty, Stephen J. \| Lalonde, Jasmin Journal of Neurochemistry, volume 158, issue 5, pages 1058-1073 (2021). 10.1111/jnc.15440 Cited by (8) \| Cite \| Source
FLEXIQuant-LF to quantify protein modification extent in label-free proteomics data (journal article) Schlaffner, Christoph N \| Kahnert, Konstantin \| Muntel, Jan \| Chauhan, Ruchi \| Renard, Bernhard Y \| Steen, Judith A \| Steen, Hanno eLife, volume 9 (2020). 10.7554/eLife.58783 Cited by (2) \| Cite \| Source
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains (journal article) Arakhamia, Tamta \| Lee, Christina E. \| Carlomagno, Yari \| Kumar, Mukesh \| Duong, Duc M. \| Wesseling, Hendrik \| Kundinger, Sean R. \| Wang, Kevin \| Williams, Dewight \| DeTure, Michael \| ... \| Fitzpatrick, Anthony W.P. Cell, volume 180, issue 4, pages 633-644.e12 (2020). 10.1016/j.cell.2020.01.027 Cited by (265) \| Cite \| Source
Overexpressing Low-Density Lipoprotein Receptor Reduces Tau-Associated Neurodegeneration Via ApoE-Dependent and Independent Mechanisms (journal article) Shi, Yang \| Andhey, Prabhakar \| Ising, Christina \| Wang, Kairuo \| Schlaffner, Christoph \| Wesseling, Hendrik \| Yamada, Kaoru \| Qin, Wei \| Manis, Melissa \| Remolina Serrano, Javier \| ... \| Holtzman, David SSRN Electronic Journal (2020). 10.2139/ssrn.3631474 Cited by (1) \| Cite \| Source
O5‐04‐04: ACCUMULATION OF MODIFICATIONS IN THE TAU CORE REGION DURING THE TAU AGGREGATION PROCESS IN ALZHEIMER'S DISEASE (journal article) Beerepoot, Pieter \| Wesseling, Hendrik \| Mair, Waltraud \| Svrdlikova, Michaela \| Cheng, Long \| Steen, Hanno \| Steen, Judith A. Alzheimer's & Dementia, volume 15, issue 7S_Part_31 (2019). 10.1016/j.jalz.2019.06.4855 Cite \| Source
Cell-Type-Specific Profiling of Alternative Translation Identifies Regulated Protein Isoform Variation in the Mouse Brain (journal article) Sapkota, Darshan \| Lake, Allison M. \| Yang, Wei \| Yang, Chengran \| Wesseling, Hendrik \| Guise, Amanda \| Uncu, Ceren \| Dalal, Jasbir S. \| Kraft, Andrew W. \| Lee, Jin-Moo \| ... \| Dougherty, Joseph D. Cell Reports, volume 26, issue 3, pages 594-607.e7 (2019). 10.1016/j.celrep.2018.12.077 Cited by (47) \| Cite \| Source
Cell type specific profiling of alternative translation identifies novel protein isoforms in the mouse brain (journal article) Sapkota, Darshan \| Lake, Allison M. \| Yang, Wei \| Yang, Chengran \| Wesseling, Hendrik \| Guise, Amanda \| Uncu, Ceren \| Dalal, Jasbir S \| Kraft, Andrew W. \| Lee, Jin-Moo \| ... \| Dougherty, Joseph D. bioRxiv (2018). 10.1101/324236 Cited by (1) \| Cite \| Source
A Cost-Effective High-Throughput Plasma and Serum Proteomics Workflow Enables Mapping of the Molecular Impact of Total Pancreatectomy with Islet Autotransplantation (journal article) Bennike, Tue Bjerg \| Bellin, Melena D. \| Xuan, Yue \| Stensballe, Allan \| Møller, Frederik Trier \| Beilman, Gregory J. \| Levy, Ofer \| Cruz-Monserrate, Zobeida \| Andersen, Vibeke \| Steen, Judith \| ... \| Steen, Hanno Journal of Proteome Research, volume 17, issue 5, pages 1983-1992 (2018). 10.1021/acs.jproteome.8b00111 Cited by (32) \| Cite \| Source

Title	Investigators	Year	Cost	Agency
Patient-Based Structural Biology of Tauopathies and TDP-43 Proteinopathies using Cryo-Electron Microscopy and Mass Spectrometry	Fitzpatrick, Anthony William Paul \| Petrucelli, Leonard \| Steen, Judith A	2020	$1,629,162	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Patient-Based Structural Biology of Tauopathies and TDP-43 Proteinopathies using Cryo-Electron Microscopy and Mass Spectrometry	Fitzpatrick, Anthony William Paul \| Petrucelli, Leonard \| Steen, Judith A	2019	$1,434,762	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Proteogenomics to characterize novel non-coding and extragenic translation	Kreiman, Gabriel \| Steen, Judith A	2018	$546,581	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Patient-Based Structural Biology of Tauopathies and TDP-43 Proteinopathies using Cryo-Electron Microscopy and Mass Spectrometry	Fitzpatrick, Anthony William Paul \| Petrucelli, Leonard \| Steen, Judith A	2018	$1,465,762	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Proteogenomics to characterize novel non-coding and extragenic translation	Kreiman, Gabriel \| Steen, Judith A	2018	$250,000	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Proteogenomics to characterize novel non-coding and extragenic translation	Kreiman, Gabriel \| Steen, Judith A	2017	$546,581	NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Regulation of SMN and Identification of its Downstream Target	Steen, Judith Jebanathirajah	2011	$440,127	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Regulation of SMN and Identification of its Downstream Target	Steen, Judith Jebanathirajah	2010	$441,577	NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE