Sophie Trefely

ScholarGPS® ID: 32580290921032

Affiliation

Temple University, Philadelphia, United States

Affiliation History

Field

Medicine

Discipline

Immunology

Top Specialties

Metabolism | Histone | Cancer | Mass Spectrometry | Microbiota

Metrics Summary

Publication Count

Predicted Citations

3,544

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis (journal article) Izzo, Luke T. \| Trefely, Sophie \| Demetriadou, Christina \| Drummond, Jack M. \| Mizukami, Takuya \| Kuprasertkul, Nina \| Farria, Aimee T. \| Nguyen, Phuong T. T. \| Murali, Nivitha \| Reich, Lauren \| ... \| Wellen, Kathryn E. Science Advances, volume 9, issue 18 (2023). 10.1126/sciadv.adf0115 Cited by (20) \| Cite \| Source
Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species (journal article) Doan, Mary T. \| Neinast, Michael D. \| Varner, Erika L. \| Bedi, Kenneth C. \| Bartee, David \| Jiang, Helen \| Trefely, Sophie \| Xu, Peining \| Singh, Jay P. \| Jang, Cholsoon \| ... \| Snyder, Nathaniel W. Journal of Lipid Research, volume 63, issue 6, pages 100224- (2022). 10.1016/j.jlr.2022.100224 Cited by (1) \| Cite \| Source
Mass Spectrometry Based Subcellular Coenzyme Analysis (journal article) Snyder, Nathaniel W. \| Bostwick, Anna \| Pepper, Hannah \| Trefely, Sophie The FASEB Journal, volume 36, issue S1 (2022). 10.1096/fasebj.2022.36.S1.R6113 Cite \| Source
O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation (journal article) Ciraku, Lorela \| Bacigalupa, Zachary A. \| Ju, Jing \| Moeller, Rebecca A. \| Le Minh, Giang \| Lee, Rusia H. \| Smith, Michael D. \| Ferrer, Christina M. \| Trefely, Sophie \| Izzo, Luke T. \| ... \| Reginato, Mauricio J. Oncogene, volume 41, issue 14, pages 2122-2136 (2022). 10.1038/s41388-022-02237-6 Cited by (27) \| Cite \| Source
Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation (journal article) Trefely, Sophie \| Huber, Katharina \| Liu, Joyce \| Noji, Michael \| Stransky, Stephanie \| Singh, Jay \| Doan, Mary T. \| Lovell, Claudia D. \| von Krusenstiern, Eliana \| Jiang, Helen \| ... \| Snyder, Nathaniel W. Molecular Cell, volume 82, issue 2, pages 447-462.e6 (2022). 10.1016/j.molcel.2021.11.006 Cited by (43) \| Cite \| Source
Glutamine deprivation triggers NAGK-dependent hexosamine salvage (journal article) Campbell, Sydney \| Mesaros, Clementina \| Izzo, Luke \| Affronti, Hayley \| Noji, Michael \| Schaffer, Bethany E \| Tsang, Tiffany \| Sun, Kathryn \| Trefely, Sophie \| Kruijning, Salisa \| ... \| Wellen, Kathryn E eLife, volume 10 (2021). 10.7554/eLife.62644 Cited by (30) \| Cite \| Source
CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production (journal article) Garcia-Canaveras, Juan \| Heo, David \| Trefely, Sophie \| Leferovich, John \| Xu, Chong \| Philipson, Benjamin \| Ghassemi, Saba \| Milone, Michael \| Moon, Edmund \| Snyder, Nathaniel \| ... \| O’Connor, Roddy Cells, volume 10, issue 9, pages 2334- (2021). 10.3390/cells10092334 Cited by (5) \| Cite \| Source
Messenger RNA 5′ NAD+ Capping Is a Dynamic Regulatory Epitranscriptome Mark That Is Required for Proper Response to Abscisic Acid in Arabidopsis (journal article) Yu, Xiang \| Willmann, Matthew R. \| Vandivier, Lee E. \| Trefely, Sophie \| Kramer, Marianne C. \| Shapiro, Jeffrey \| Guo, Rong \| Lyons, Eric \| Snyder, Nathaniel W. \| Gregory, Brian D. Developmental Cell, volume 56, issue 1, pages 125-140.e6 (2021). 10.1016/j.devcel.2020.11.009 Cited by (34) \| Cite \| Source
Quantitative Sub-Cellular Acyl-Coa Analysis Reveals Distinct Nuclear Regulation (journal article) Trefely, Sophie \| Huber, Katharina \| Liu, Joyce \| Noji, Michael \| Stransky, Stephanie \| Singh, Jay \| Doan, Mary T. \| Lovell, Claudia D. \| von Krusenstiern, Eliana \| Jiang, Helen \| ... \| Snyder, Nathaniel SSRN Electronic Journal (2021). 10.2139/ssrn.3885983 Cite \| Source
Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues (journal article) Varner, Erika L. \| Trefely, Sophie \| Bartee, David \| von Krusenstiern, Eliana \| Izzo, Luke \| Bekeova, Carmen \| O'Connor, Roddy S. \| Seifert, Erin L. \| Wellen, Kathryn E. \| Meier, Jordan L. \| Snyder, Nathaniel W. Open Biology, volume 10, issue 9 (2020). 10.1098/rsob.200187 Cited by (44) \| Cite \| Source
Compartmentalised acyl-CoA metabolism and roles in chromatin regulation (journal article) Trefely, Sophie \| Lovell, Claudia D. \| Snyder, Nathaniel W. \| Wellen, Kathryn E. Molecular Metabolism, volume 38 (2020). 10.1016/j.molmet.2020.01.005 Cited by (141) \| Cite \| Source
Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate (journal article) Zhao, Steven \| Jang, Cholsoon \| Liu, Joyce \| Uehara, Kahealani \| Gilbert, Michael \| Izzo, Luke \| Zeng, Xianfeng \| Trefely, Sophie \| Fernandez, Sully \| Carrer, Alessandro \| ... \| Wellen, Kathryn E. Nature, volume 579, issue 7800, pages 586-591 (2020). 10.1038/s41586-020-2101-7 Cited by (314) \| Cite \| Source
P165 INFLUENCE OF THE GUT MICROBIOTA ON COLONIC HISTONE MODIFICATIONS THROUGH BUTYRATE METABOLISM UNDER HEALTHY AND INFLAMMATORY CONDITIONS (journal article) Lund, Peder \| Smith, Sarah \| Simithy, Johayra \| Chau, Lillian \| Friedman, Elliot \| Saiman, Yedidya \| Gates, Leah \| Leboeuf, Marylene \| Trefely, Sophie \| Lopes, Mariana \| ... \| Garcia, Benjamin Gastroenterology, volume 158, issue 3, pages S67- (2020). 10.1053/j.gastro.2019.11.170 Cite \| Source
mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis (journal article) Martinez Calejman, C. \| Trefely, S. \| Entwisle, S. W. \| Luciano, A. \| Jung, S. M. \| Hsiao, W. \| Torres, A. \| Hung, C. M. \| Li, H. \| Snyder, N. W. \| ... \| Guertin, D. A. Nature Communications, volume 11, issue 1 (2020). 10.1038/s41467-020-14430-w Cited by (82) \| Cite \| Source
P165 INFLUENCE OF THE GUT MICROBIOTA ON COLONIC HISTONE MODIFICATIONS THROUGH BUTYRATE METABOLISM UNDER HEALTHY AND INFLAMMATORY CONDITIONS (journal article) Lund, Peder \| Smith, Sarah \| Simithy, Johayra \| Chau, Lillian \| Friedman, Elliot \| Saiman, Yedidya \| Gates, Leah \| Leboeuf, Marylene \| Trefely, Sophie \| Lopes, Mariana \| ... \| Garcia, Benjamin Inflammatory Bowel Diseases, volume 26, issue Supplement_1, pages S40-S41 (2020). 10.1093/ibd/zaa010.105 Cite \| Source
Subcellular metabolic pathway kinetics are revealed by correcting for artifactual post harvest metabolism (journal article) Trefely, Sophie \| Liu, Joyce \| Huber, Katharina \| Doan, Mary T. \| Jiang, Helen \| Singh, Jay \| von Krusenstiern, Eliana \| Bostwick, Anna \| Xu, Peining \| Bogner-Strauss, Juliane G. \| ... \| Snyder, Nathaniel W. Molecular Metabolism, volume 30 (2019). 10.1016/j.molmet.2019.09.004 Cited by (21) \| Cite \| Source
Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy (journal article) Kopinski, Piotr K. \| Janssen, Kevin A. \| Schaefer, Patrick M. \| Trefely, Sophie \| Perry, Caroline E. \| Potluri, Prasanth \| Tintos-Hernandez, Jesus A. \| Singh, Larry N. \| Karch, Kelly R. \| Campbell, Sydney L. \| ... \| Wallace, Douglas C. Proceedings of the National Academy of Sciences, volume 116, issue 32, pages 16028-16035 (2019). 10.1073/pnas.1906896116 Cited by (105) \| Cite \| Source
A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate (journal article) Wang, Wenshan \| Ishibashi, Jeff \| Trefely, Sophie \| Shao, Mengle \| Cowan, Alexis J. \| Sakers, Alexander \| Lim, Hee-Woong \| O’Connor, Sean \| Doan, Mary T. \| Cohen, Paul \| ... \| Seale, Patrick Cell Metabolism, volume 30, issue 1, pages 174-189.e5 (2019). 10.1016/j.cmet.2019.05.005 Cited by (145) \| Cite \| Source
Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females (journal article) Fernandez, Sully \| Viola, John M. \| Torres, AnnMarie \| Wallace, Martina \| Trefely, Sophie \| Zhao, Steven \| Affronti, Hayley C. \| Gengatharan, Jivani M. \| Guertin, David A. \| Snyder, Nathaniel W. \| ... \| Wellen, Kathryn E. Cell Reports, volume 27, issue 9, pages 2772-2784.e6 (2019). 10.1016/j.celrep.2019.04.112 Cited by (52) \| Cite \| Source
Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis (journal article) Carrer, Alessandro \| Trefely, Sophie \| Zhao, Steven \| Campbell, Sydney L. \| Norgard, Robert J. \| Schultz, Kollin C. \| Sidoli, Simone \| Parris, Joshua L.D. \| Affronti, Hayley C. \| Sivanand, Sharanya \| ... \| Wellen, Kathryn E. Cancer Discovery, volume 9, issue 3, pages 416-435 (2019). 10.1158/2159-8290.CD-18-0567 Cited by (186) \| Cite \| Source