Kathleen M. Loomes

ScholarGPS® ID: 29136190544813

Affiliation

Children's Hospital of Philadelphia

Affiliation History

Field

Allied Health

Discipline

Nutritional Sciences and Dietetics

Top Specialties

Metrics Summary

Publication Count

141

Predicted Citations

5,475

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Identification of pediatric activated T-cell hepatitis using clinical immune studies (journal article) Chapin, Catherine A \| Diamond, Tamir \| Perez, Adriana \| Kreiger, Portia A \| Loomes, Kathleen M \| Behrens, Edward M \| Alonso, Estella M Clinics and Research in Hepatology and Gastroenterology, volume 48, issue 7, pages 102407- (2024). 10.1016/j.clinre.2024.102407 Cite \| Source
WED-166 Efficacy and safety of odevixibat in a subgroup of adult patients with progressive familial intrahepatic cholestasis in the PEDFIC 2 study (journal article) Verkade, Henkjan J. \| Loomes, Kathleen M. \| Stoll, Janis M. \| Gu, Tao \| Loizides, Anthony \| Maucksch, Christof Journal of Hepatology, volume 80 (2024). 10.1016/S0168-8278(24)02023-3 Cite \| Source
Effector memory CD8 T-cells as a novel peripheral blood biomarker for activated T-cell pediatric acute liver failure (journal article) Chapin, Catherine A. \| Burn, Thomas M. \| Diamond, Tamir \| Loomes, Kathleen M. \| Alonso, Estella M. \| Behrens, Edward M. PLOS ONE, volume 18, issue 6, pages e0286394- (2023). 10.1371/journal.pone.0286394 Cited by (3) \| Cite \| Source
Blood markers of immune activation help distinguish paediatric activated T-cell hepatitis from other causes (journal article) Diamond, Tamir \| Chapin, Catherine \| Perez, Adriana \| Loomes, Kathleen M. \| Behrens, Edward \| Alonso, Estella Journal of Hepatology, volume 78 (2023). 10.1016/S0168-8278(23)03011-8 Cite \| Source
Neonatal cholestasis in children with Alpha-1-AT deficiency is a risk for earlier severe liver disease with male predominance (journal article) Teckman, Jeffrey \| Rosenthal, Philip \| Ignacio, Rosalinda V. \| Spino, Cathie \| Bass, Lee M. \| Horslen, Simon \| Wang, Kasper \| Magee, John C. \| Karpen, Saul \| Asai, Akihiro \| ... \| Sokol, Ronald J. Hepatology Communications, volume 7, issue 12 (2023). 10.1097/HC9.0000000000000345 Cite \| Source
Sarcopenia is associated with osteopenia and impaired quality of life in children with genetic intrahepatic cholestatic liver disease (journal article) Boster, Julia M. \| Goodrich, Nathan P. \| Spino, Cathie \| Loomes, Kathleen M. \| Alonso, Estella M. \| Kamath, Binita M. \| Sokol, Ronald J. \| Karpen, Saul \| Miethke, Alexander \| Shneider, Benjamin L. \| ... \| Sundaram, Shikha S. Hepatology Communications, volume 7, issue 11 (2023). 10.1097/HC9.0000000000000293 Cited by (1) \| Cite \| Source
Adenovirus is Not Detected in Liver Tissue From a Historical Multicenter Cohort of Children With Acute Liver Failure (journal article) Chapin, Catherine A. \| Diamond, Tamir \| Harris, Rebecca M. \| Vaccaro, Olivia \| Loomes, Kathleen M. \| Alonso, Estella M. \| Behrens, Edward M. Journal of Pediatric Gastroenterology & Nutrition, volume 77, issue 3, pages 393-395 (2023). 10.1097/MPG.0000000000003851 Cited by (1) \| Cite \| Source
Changes in hepatic parameters, growth, sleep, and biochemical markers with odevixibat treatment across patients with various types of progressive familial intrahepatic cholestasis (journal article) D’Antiga, Lorenzo \| Gupte, Girish \| Thompson, Richard J. \| Sturm, Ekkehard \| Calvo, Pier Luigi \| Shagrani, Mohammad Ali \| Stoll, Janis M. \| Artan, Reha \| Dalgıç, Buket \| Ozen, Hasan \| ... \| Horn, Patrick Journal of Hepatology, volume 77 (2022). 10.1016/S0168-8278(22)01361-7 Cite \| Source
EP1231: ODEVIXIBAT THERAPY IMPROVES CLINICALLY MEANINGFUL ENDPOINTS IN CHILDREN WITH PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS: DATA FROM THE PEDFIC 1 AND PEDFIC 2 TRIALS (journal article) Thompson, Richard J. \| D'Antiga, Lorenzo \| Gonzalès, Emmanuel \| Karpen, Saul J. \| Kjems, Lise \| Loomes, Kathleen \| Mack, Cara L. \| Ni, Quanhong \| Verkade, Henkjan J. \| Horn, Patrick Gastroenterology, volume 162, issue 7, pages S-1296- (2022). 10.1016/S0016-5085(22)63792-2 Cited by (3) \| Cite \| Source
L3 Effects on serum bile acids, pruritus, and safety with up to 72 weeks of odevixibat treatment: pooled data from the PEDFIC 1 and PEDFIC 2 studies in children with progressive familial intrahepatic cholestasis (conference) Loomes, Kathleen M \| Verkade, Henkjan J \| Thompson, Richard J \| Kamath, Binita M \| Hardikar, Winita \| Lacaille, Florence \| Mozer-Glassberg, Yael \| Shteyer, Eyal \| Calvo, Pier Luigi \| Dalgic, Buket \| ... \| Horn, Patrick Abstracts of the BSPGHAN Annual Meeting, 25–27 April 2022 (2022) 10.1136/flgastro-2022-bspghan.66 Cite \| Source
Maralixibat for the treatment of PFIC: Long‐term, IBAT inhibition in an open‐label, Phase 2 study (journal article) Loomes, Kathleen M. \| Squires, Robert H. \| Kelly, Deirdre \| Rajwal, Sanjay \| Soufi, Nisreen \| Lachaux, Alain \| Jankowska, Irena \| Mack, Cara \| Setchell, Kenneth D. R. \| Karthikeyan, Palaniswamy \| ... \| Thompson, Richard J. Hepatology Communications, volume 6, issue 9, pages 2379-2390 (2022). 10.1002/hep4.1980 Cited by (34) \| Cite \| Source
Risk of variceal hemorrhage and pretransplant mortality in children with biliary atresia (journal article) Bass, Lee M. \| Ye, Wen \| Hawthorne, Kieran \| Leung, Daniel H. \| Murray, Karen F. \| Molleston, Jean P. \| Romero, Rene \| Karpen, Saul \| Rosenthal, Philip \| Loomes, Kathleen M. \| ... \| Shneider, Benjamin L. Hepatology, volume 76, issue 3, pages 712-726 (2022). 10.1002/hep.32451 Cited by (11) \| Cite \| Source
Use of funded multicenter prospective longitudinal databases to inform clinical trials in rare diseases—Examination of cholestatic liver disease in Alagille syndrome (journal article) Shneider, Benjamin L. \| Kamath, Binita M. \| Magee, John C. \| Goodrich, Nathan P. \| Loomes, Kathleen M. \| Ye, Wen \| Spino, Cathie \| Alonso, Estella M. \| Molleston, Jean P. \| Bezerra, Jorge A. \| ... \| Sokol, Ronald J. Hepatology Communications, volume 6, issue 8, pages 1910-1921 (2022). 10.1002/hep4.1970 Cited by (3) \| Cite \| Source
Cholestatic liver diseases of genetic etiology: Advances and controversies (journal article) Ibrahim, Samar H. \| Kamath, Binita M. \| Loomes, Kathleen M. \| Karpen, Saul J. Hepatology, volume 75, issue 6, pages 1627-1646 (2022). 10.1002/hep.32437 Cited by (23) \| Cite \| Source
Neurodevelopmental Outcomes in Children With Inherited Liver Disease and Native Liver (journal article) Leung, Daniel H. \| Sorensen, Lisa G. \| Ye, Wen \| Hawthorne, Kieran \| Ng, Vicky L. \| Loomes, Kathleen M. \| Fredericks, Emily M. \| Alonso, Estella M. \| Heubi, James E. \| Horslen, Simon P. \| ... \| Magee, John C. Journal of Pediatric Gastroenterology and Nutrition, volume 74, issue 1, pages 96-103 (2022). 10.1097/MPG.0000000000003337 Cited by (5) \| Cite \| Source
Alagille Syndrome: A Focused Review on Clinical Features, Genetics, and Treatment (journal article) Kohut, Taisa J. \| Gilbert, Melissa A. \| Loomes, Kathleen M. Seminars in Liver Disease, volume 41, issue 04, pages 525-537 (2021). 10.1055/s-0041-1730951 Cited by (33) \| Cite \| Source
Mutation Analysis and Disease Features at Presentation in a Multi‐Center Cohort of Children With Monogenic Cholestasis (journal article) Hertel, Paula M. \| Bull, Laura N. \| Thompson, Richard J. \| Goodrich, Nathan P. \| Ye, Wen \| Magee, John C. \| Squires, Robert H. \| Bass, Lee M. \| Heubi, James E. \| Kim, Grace E. \| ... \| Shneider, Benjamin L. Journal of Pediatric Gastroenterology and Nutrition, volume 73, issue 2, pages 169-177 (2021). 10.1097/MPG.0000000000003153 Cited by (8) \| Cite \| Source
A new syndrome of moyamoya disease, kidney dysplasia, aminotransferase elevation, and skin disease associated with de novo variants in RNF213 (journal article) Strong, Alanna \| O'Grady, Gina \| Shih, Evelyn \| Bishop, Jonathan R. \| Loomes, Kathleen \| Diamond, Tamir \| Hartung, Erum A. \| Wong, William \| Cuddapah, Sanmati \| Cahill, Anne Marie \| ... \| Hakonarson, Hakon American Journal of Medical Genetics Part A, volume 185, issue 7, pages 2168-2174 (2021). 10.1002/ajmg.a.62215 Cited by (9) \| Cite \| Source
Alagille syndrome and non-syndromic paucity of the intrahepatic bile ducts (journal article) Gilbert, Melissa A. \| Loomes, Kathleen M. Translational Gastroenterology and Hepatology, volume 6 (2021). 10.21037/tgh-2020-03 Cited by (10) \| Cite \| Source
TRMU deficiency: a broad clinical spectrum responsive to cysteine supplementation (journal article) Murali, Chaya \| Soler-Alfonso, Claudia \| Loomes, Kathleen \| Shah, Amit \| Monteil, Danielle \| Padilla, Carmencita \| Scaglia, Fernando \| Ganetzky, Rebecca Molecular Genetics and Metabolism, volume 132 (2021). 10.1016/S1096-7192(21)00106-2 Cite \| Source

Title	Investigators	Year	Cost	Agency
Advancing our Understanding of Rare Pediatric Liver Diseases	Loomes, Kathleen Mary	2020	$177,660	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Advancing our Understanding of Rare Pediatric Liver Diseases	Loomes, Kathleen Mary	2020	$449,550	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Training Program in the Genetic Basis of Pediatric Gastrointestinal Disorders	Loomes, Kathleen Mary \| Spinner, Nancy Bettina	2020	$241,785	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Advancing our Understanding of Rare Pediatric Liver Diseases	Loomes, Kathleen Mary	2019	$272,720	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Training Program in the Genetic Basis of Pediatric Gastrointestinal Disorders	Loomes, Kathleen Mary \| Spinner, Nancy Bettina	2019	$216,984	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Advancing our Understanding of Rare Pediatric Liver Diseases	Loomes, Kathleen Mary	2018	$363,958	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Advancing our Understanding of Rare Pediatric Liver Diseases	Loomes, Kathleen Mary	2017	$117,600	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Advancing our Understanding of Rare Pediatric Liver Diseases	Loomes, Kathleen Mary	2017	$354,337	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Advancing our Understanding of Rare Pediatric Liver Diseases	Loomes, Kathleen Mary	2016	$309,857	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Advancing our Understanding of Rare Pediatric Liver Diseases	Loomes, Kathleen Mary	2015	$289,360	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Advancing our Understanding of Rare Pediatric Liver Diseases	Loomes, Kathleen Mary	2014	$416,458	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Advancing our Understanding of Rare Pediatric Liver Diseases	Loomes, Kathleen Mary	2013	$383,745	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Advancing our Understanding of Rare Pediatric Liver Diseases	Loomes, Kathleen Mary	2012	$373,500	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Advancing our Understanding of Rare Pediatric Liver Diseases	Loomes, Kathleen Mary	2011	$457,962	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
The Role of the Notch Pathway in Bile Duct Development	Loomes, Kathleen Mary	2010	$99,998	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
The Role of the Notch Pathway in Bile Duct Development	Loomes, Kathleen Mary	2009	$339,350	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
The Role of the Notch Pathway in Bile Duct Development	Loomes, Kathleen Mary	2008	$339,350	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
The Role of the Notch Pathway in Bile Duct Development	Loomes, Kathleen Mary	2007	$346,276	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
The Role of the Notch Pathway in Bile Duct Development	Loomes, Kathleen Mary	2006	$356,618	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
The Role of the Notch Pathway in Bile Duct Development	Loomes, Kathleen Mary	2005	$365,200	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
THE ROLE OF NOTCH SIGNALING IN BILE DUCT DEVELOPMENT	Loomes, Kathleen Mary	2004	$85,000	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
SIGNALING MOLECULES IN BILE DUCT DEVELOPMENT	Loomes, Kathleen Mary	2004	$131,247	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
THE ROLE OF NOTCH SIGNALING IN BILE DUCT DEVELOPMENT	Loomes, Kathleen Mary	2003	$85,000	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
SIGNALING MOLECULES IN BILE DUCT DEVELOPMENT	Loomes, Kathleen Mary	2003	$132,327	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
SIGNALING MOLECULES IN BILE DUCT DEVELOPMENT	Loomes, Kathleen Mary	2002	$131,247	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
SIGNALING MOLECULES IN BILE DUCT DEVELOPMENT	Loomes, Kathleen Mary	2001	$125,847	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
SIGNALING MOLECULES IN BILE DUCT DEVELOPMENT	Loomes, Kathleen Mary	2000	$125,847	NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES