Emily Chan

ScholarGPS® ID: 28846487160772

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Medicine

Discipline

Oncology

Top Specialties

Cancer | Neoplasm

Metrics Summary

Publication Count

Predicted Citations

2,658

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Tissue distribution and retention drives efficacy of rapidly clearing VHL-based PROTACs (journal article) Zhang, Donglu \| Ma, Bin \| Dragovich, Peter S. \| Ma, Li \| Chen, Shu \| Chen, Eugene C. \| Ye, Xiaofen \| Liu, Joyce \| Pizzano, Jennifer \| Bortolon, Elizabeth \| ... \| Hop, Cornelis E. C. A. Communications Medicine, volume 4, issue 1 (2024). 10.1038/s43856-024-00505-y Cited by (1) \| Cite \| Source
Regulation of Tumor-Associated Myeloid Cell Activity by CBP/EP300 Bromodomain Modulation of H3K27 Acetylation (journal article) de Almeida Nagata, Denise E. \| Chiang, Eugene Y. \| Jhunjhunwala, Suchit \| Caplazi, Patrick \| Arumugam, Vidhyalakshmi \| Modrusan, Zora \| Chan, Emily \| Merchant, Mark \| Jin, Lingyan \| Arnott, David \| ... \| Grogan, Jane L. Cell Reports, volume 27, issue 1, pages 269-281.e4 (2019). 10.1016/j.celrep.2019.03.008 Cited by (39) \| Cite \| Source
Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation (journal article) Raisner, Ryan \| Kharbanda, Samir \| Jin, Lingyan \| Jeng, Edwin \| Chan, Emily \| Merchant, Mark \| Haverty, Peter M. \| Bainer, Russell \| Cheung, Tommy \| Arnott, David \| ... \| Gascoigne, Karen E. Cell Reports, volume 24, issue 7, pages 1722-1729 (2018). 10.1016/j.celrep.2018.07.041 Cited by (202) \| Cite \| Source \| Open Access
Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer (journal article) Jin, Lingyan \| Garcia, Jesse \| Chan, Emily \| de la Cruz, Cecile \| Segal, Ehud \| Merchant, Mark \| Kharbanda, Samir \| Raisner, Ryan \| Haverty, Peter M. \| Modrusan, Zora \| ... \| Gascoigne, Karen E. Cancer Research, volume 77, issue 20, pages 5564-5575 (2017). 10.1158/0008-5472.CAN-17-0314 Cited by (103) \| Cite \| Source \| Open Access
Cotargeting of MEK and PDGFR/STAT3 Pathways to Treat Pancreatic Ductal Adenocarcinoma (journal article) Sahu, Nisebita \| Chan, Emily \| Chu, Felix \| Pham, Thinh \| Koeppen, Hartmut \| Forrest, William \| Merchant, Mark \| Settleman, Jeff Molecular Cancer Therapeutics, volume 16, issue 9, pages 1729-1738 (2017). 10.1158/1535-7163.MCT-17-0009 Cited by (25) \| Cite \| Source
Modeling Targeted Inhibition of MEK and PI3 Kinase in Human Pancreatic Cancer (journal article) Junttila, Melissa R. \| Devasthali, Vidusha \| Cheng, Jason H. \| Castillo, Joseph \| Metcalfe, Ciara \| Clermont, Anne C. \| Otter, Douglas Den \| Chan, Emily \| Bou-Reslan, Hani \| Cao, Tim \| ... \| Singh, Mallika Molecular Cancer Therapeutics, volume 14, issue 1, pages 40-47 (2015). 10.1158/1535-7163.MCT-14-0030 Cited by (42) \| Cite \| Source \| Open Access
A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation–Driven Colorectal Tumor Growth (journal article) Lau, Ted \| Chan, Emily \| Callow, Marinella \| Waaler, Jo \| Boggs, Jason \| Blake, Robert A. \| Magnuson, Steven \| Sambrone, Amy \| Schutten, Melissa \| Firestein, Ron \| ... \| Costa, Mike Cancer Research, volume 73, issue 10, pages 3132-3144 (2013). 10.1158/0008-5472.CAN-12-4562 Cited by (266) \| Cite \| Source \| Open Access
Noncovalent Wild-type–Sparing Inhibitors of EGFR T790M (journal article) Lee, Ho-June \| Schaefer, Gabriele \| Heffron, Timothy P. \| Shao, Lily \| Ye, Xiaofen \| Sideris, Steve \| Malek, Shiva \| Chan, Emily \| Merchant, Mark \| La, Hank \| ... \| Settleman, Jeff Cancer Discovery, volume 3, issue 2, pages 168-181 (2013). 10.1158/2159-8290.CD-12-0357 Cited by (79) \| Cite \| Source \| Open Access
FGFR3 Stimulates Stearoyl CoA Desaturase 1 Activity to Promote Bladder Tumor Growth (journal article) Du, Xiangnan \| Wang, Qian-Rena \| Chan, Emily \| Merchant, Mark \| Liu, Jinfeng \| French, Dorothy \| Ashkenazi, Avi \| Qing, Jing Cancer Research, volume 72, issue 22, pages 5843-5855 (2012). 10.1158/0008-5472.CAN-12-1329 Cited by (72) \| Cite \| Source \| Open Access
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors (journal article) Wilson, Timothy R. \| Fridlyand, Jane \| Yan, Yibing \| Penuel, Elicia \| Burton, Luciana \| Chan, Emily \| Peng, Jing \| Lin, Eva \| Wang, Yulei \| Sosman, Jeff \| ... \| Settleman, Jeff Nature, volume 487, issue 7408, pages 505-509 (2012). 10.1038/nature11249 Cited by (989) \| Cite \| Source \| Open Access
Discovery of Novel Allosteric Mitogen-Activated Protein Kinase Kinase (MEK) 1,2 Inhibitors Possessing Bidentate Ser212 Interactions (journal article) Heald, Robert A. \| Jackson, Philip \| Savy, Pascal \| Jones, Mark \| Gancia, Emanuela \| Burton, Brenda \| Newman, Richard \| Boggs, Jason \| Chan, Emily \| Chan, Jocelyn \| ... \| Price, Steve Journal of Medicinal Chemistry, volume 55, issue 10, pages 4594-4604 (2012). 10.1021/jm2017094 Cited by (32) \| Cite \| Source
Abstract A250: Preclinical combination efficacy and identification of biomarkers of MEK and PI3K inhibitors in phase I (journal article) Hoeflich, Klaus \| Merchant, Mark \| Den Otter, Doug \| Chan, Jocelyn \| Chan, Emily \| Orr, Christine \| Friedman, Lori \| Chan, Iris \| Prescott, John \| Berry, Leanne \| ... \| Belvin, Marcia Molecular Cancer Therapeutics, volume 8, issue 12_Supplement, pages A250-A250 (2009). 10.1158/1535-7163.TARG-09-A250 Cited by (1) \| Cite \| Source