Valérie Le Fourn

ScholarGPS® ID: 28166180634871

Affiliation

University of Lausanne, Lausanne,Chavannes-près-Renens,Écublens,Saint-Sulpice andÉpalinges, Switzerland

Affiliation History

Field

Medicine

Discipline

Pathology

Top Specialties

Biotechnology | Immortalised Cell Line | Autophagy

Metrics Summary

Publication Count

Predicted Citations

835

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

Add Delete
Back Cover Image, Volume 117, Number 12, December 2020 (journal article) Kuhn, Alexandre \| Le Fourn, Valérie \| Fisch, Igor \| Mermod, Nicolas Biotechnology and Bioengineering, volume 117, issue 12 (2020). 10.1002/bit.27068 Cite \| Source
Genome‐wide analysis of single nucleotide variants allows for robust and accurate assessment of clonal derivation in cell lines used to produce biologics (journal article) Kuhn, Alexandre \| Le Fourn, Valérie \| Fisch, Igor \| Mermod, Nicolas Biotechnology and Bioengineering, volume 117, issue 12, pages 3628-3638 (2020). 10.1002/bit.27534 Cited by (2) \| Cite \| Source
Transient vitamin B5 starving improves mammalian cell homeostasis and protein production (journal article) Pourcel, Lucille \| Buron, Flavien \| Garcia, Fanny \| Delaloix, Margaux-Sarah \| Le Fourn, Valérie \| Girod, Pierre-Alain \| Mermod, Nicolas Metabolic Engineering, volume 60 (2020). 10.1016/j.ymben.2020.03.008 Cited by (15) \| Cite \| Source
Influence of cytoskeleton organization on recombinant protein expression by CHO cells (journal article) Pourcel, Lucille \| Buron, Flavien \| Arib, Ghislaine \| Le Fourn, Valérie \| Regamey, Alexandre \| Bodenmann, Iris \| Girod, Pierre‐Alain \| Mermod, Nicolas Biotechnology and Bioengineering, volume 117, issue 4, pages 1117-1126 (2020). 10.1002/bit.27277 Cited by (14) \| Cite \| Source
Overexpression of transcription factor Foxa1 and target genes remediate therapeutic protein production bottlenecks in Chinese hamster ovary cells (journal article) Berger, Audrey \| Le Fourn, Valérie \| Masternak, Jacqueline \| Regamey, Alexandre \| Bodenmann, Iris \| Girod, Pierre‐Alain \| Mermod, Nicolas Biotechnology and Bioengineering, volume 117, issue 4, pages 1101-1116 (2020). 10.1002/bit.27274 Cited by (25) \| Cite \| Source
Cleavage-Independent HIV-1 Trimers From CHO Cell Lines Elicit Robust Autologous Tier 2 Neutralizing Antibodies (journal article) Bale, Shridhar \| Martiné, Alexandra \| Wilson, Richard \| Behrens, Anna-Janina \| Le Fourn, Valérie \| de Val, Natalia \| Sharma, Shailendra K. \| Tran, Karen \| Torres, Jonathan L. \| Girod, Pierre-Alain \| ... \| Wyatt, Richard T. Frontiers in Immunology, volume 9 (2018). 10.3389/fimmu.2018.01116 Cited by (25) \| Cite \| Source \| Open Access
Cover Image, Volume 114, Number 8, August 2017 (journal article) Droz, Xuan \| Harraghy, Niamh \| Lançon, Etienne \| Le Fourn, Valérie \| Calabrese, David \| Colombet, Thierry \| Liechti, Pascal \| Rida, Amar \| Girod, Pierre‐Alain \| Mermod, Nicolas Biotechnology and Bioengineering, volume 114, issue 8 (2017). 10.1002/bit.26148 Cite \| Source \| Open Access
Automated microfluidic sorting of mammalian cells labeled with magnetic microparticles for those that efficiently express and secrete a protein of interest (journal article) Droz, Xuan \| Harraghy, Niamh \| Lançon, Etienne \| Le Fourn, Valérie \| Calabrese, David \| Colombet, Thierry \| Liechti, Pascal \| Rida, Amar \| Girod, Pierre‐Alain \| Mermod, Nicolas Biotechnology and Bioengineering, volume 114, issue 8, pages 1791-1802 (2017). 10.1002/bit.26270 Cited by (7) \| Cite \| Source
MAR‐Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering (journal article) Kostyrko, Kaja \| Neuenschwander, Samuel \| Junier, Thomas \| Regamey, Alexandre \| Iseli, Christian \| Schmid‐Siegert, Emanuel \| Bosshard, Sandra \| Majocchi, Stefano \| Le Fourn, Valérie \| Girod, Pierre‐Alain \| ... \| Mermod, Nicolas Biotechnology and Bioengineering, volume 114, issue 2, pages 384-396 (2017). 10.1002/bit.26086 Cited by (22) \| Cite \| Source \| Open Access
MAR elements and transposons for improved transgene integration and expression (journal article) Ley, Déborah \| Le Fourn, Valérie \| Girod, Pierre-Alain \| Regamey, Alexandre \| Mermod, Nicolas New Biotechnology, volume 31 (2014). 10.1016/j.nbt.2014.05.945 Cite \| Source \| Open Access
CHO cell engineering to prevent polypeptide aggregation and improve therapeutic protein secretion (journal article) Le Fourn, Valérie \| Girod, Pierre-Alain \| Buceta, Montse \| Regamey, Alexandre \| Mermod, Nicolas Metabolic Engineering, volume 21 (2014). 10.1016/j.ymben.2012.12.003 Cited by (126) \| Cite \| Source \| Open Access
High performance CHO cell line development platform for enhanced production of recombinant proteins including difficult-to-express proteins (journal article) Girod, Pierre-Alain \| Le Fourn, Valérie \| Calabrese, David \| Regamey, Alexandre \| Ley, Deborah \| Mermod, Nicolas BMC Proceedings, volume 7, issue S6 (2013). 10.1186/1753-6561-7-S6-P75 Cite \| Source \| Open Access
Large protein complexes retained in the ER are dislocated by non-COPII vesicles and degraded by selective autophagy (journal article) Le Fourn, Valerie \| Park, Sujin \| Jang, Insook \| Gaplovska-Kysela, Katarina \| Guhl, Bruno \| Lee, Yangsin \| Cho, Jin Won \| Zuber, Christian \| Roth, Jürgen Cellular and Molecular Life Sciences, volume 70, issue 11, pages 1985-2002 (2013). 10.1007/s00018-012-1236-6 Cited by (20) \| Cite \| Source \| Open Access
MAR Elements and Transposons for Improved Transgene Integration and Expression (journal article) Ley, Déborah \| Harraghy, Niamh \| Le Fourn, Valérie \| Bire, Solenne \| Girod, Pierre-Alain \| Regamey, Alexandre \| Rouleux-Bonnin, Florence \| Bigot, Yves \| Mermod, Nicolas PLoS ONE, volume 8, issue 4, pages e62784- (2013). 10.1371/journal.pone.0062784 Cited by (32) \| Cite \| Source \| Open Access
Protein N-Glycosylation, Protein Folding, and Protein Quality Control (journal article) Roth, Jürgen \| Zuber, Christian \| Park, Sujin \| Jang, Insook \| Lee, Yangsin \| Kysela, Katarina Gaplovska \| Fourn, Valérie Le \| Santimaria, Roger \| Guhl, Bruno \| Cho, Jin Won Molecules and Cells, volume 30, issue 6, pages 497-506 (2010). 10.1007/s10059-010-0159-z Cited by (137) \| Cite \| Source
Basal autophagy is involved in the degradation of the ERAD component EDEM1 (journal article) Le Fourn, V. \| Gaplovska-Kysela, K. \| Guhl, B. \| Santimaria, R. \| Zuber, C. \| Roth, J. Cellular and Molecular Life Sciences, volume 66, issue 8, pages 1434-1445 (2009). 10.1007/s00018-009-9038-1 Cited by (38) \| Cite \| Source \| Open Access
Protein quality control: the who’s who, the where’s and therapeutic escapes (journal article) Roth, Jürgen \| Yam, Gary Hin-Fai \| Fan, Jingyu \| Hirano, Kiyoko \| Gaplovska-Kysela, Katarina \| Le Fourn, Valerie \| Guhl, Bruno \| Santimaria, Roger \| Torossi, Tania \| Ziak, Martin \| Zuber, Christian Histochemistry and Cell Biology, volume 129, issue 2, pages 163-177 (2008). 10.1007/s00418-007-0366-7 Cited by (38) \| Cite \| Source \| Open Access
Competition between Calnexin and BiP in the Endoplasmic Reticulum Can Lead to the Folding or Degradation of Human Thyroperoxidase† (journal article) Le Fourn, Valérie \| Siffroi-Fernandez, Sandrine \| Ferrand, Mireille \| Franc, Jean-Louis Biochemistry, volume 45, issue 23, pages 7380-7388 (2006). 10.1021/bi060415i Cited by (11) \| Cite \| Source
Endoproteolytic Cleavage of Human Thyroperoxidase (journal article) Le Fourn, Valérie \| Ferrand, Mireille \| Franc, Jean-Louis Journal of Biological Chemistry, volume 280, issue 6, pages 4568-4577 (2005). 10.1074/jbc.M408042200 Cited by (22) \| Cite \| Source \| Open Access
Differential expression of thyroperoxidase mRNA splice variants in human thyroid tumors (journal article) Le Fourn, Valérie \| Ferrand, Mireille \| Franc, Jean-Louis Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, volume 1689, issue 2, pages 134-141 (2004). 10.1016/j.bbadis.2004.03.001 Cited by (15) \| Cite \| Source \| Open Access