Bruce D. Dorsey

ScholarGPS® ID: 27900396226905

Affiliation
Cancer Research Technology Limited, London
Affiliation History

Field
Physical Sciences and Mathematics
Discipline
Chemistry
Top Specialties
Medicinal Chemistry | HIV | HIV-1 Protease | Lymphoma | Chemical Synthesis | HIV/AIDS | Cancer | Protein Kinase | Protein Kinase Inhibitor | Oral Administration
Metrics Summary
Publication Count
99
Predicted Citations
4,966
Predicted h-index
33
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
You must register and claim your profile to add or remove publications from it.
... publications
FILTER BY:
Year
Type
Specialty
Affiliations
Access
Co-Authors
Add
Delete
Structure–Activity Relationships and Discovery of ( S )-6-Isopropyl-2-methoxy-3-(3-methoxypropoxy)-10-oxo-5,10-dihydro-6 H -pyrido[1,2- h ][1,7]naphthyridine-9-carboxylic Acid (AB-452), a Novel Orally Available HBV RNA Destabilizer (journal article)
Gotchev, Dimitar | Dorsey, Bruce D. | Nguyen, Duyan | Kakarla, Ramesh | Dugan, Benjamin | Chen, Shuai | Gao, Min | Bailey, Laurèn | Liu, Fei | Harasym, Troy | ... | Sofia, Michael J.
Journal of Medicinal Chemistry, volume 67, issue 2, pages 1421-1446 (2024).
10.1021/acs.jmedchem.3c01981
Cited by (1) | Cite | Source
Design, synthesis, and structure-activity relationship of a bicyclic HBV capsid assembly modulator chemotype leading to the identification of clinical candidate AB-506 (journal article)
Cole, Andrew G. | Kultgen, Steven G. | Mani, Nagraj | Quintero, Jorge G. | Yi Fan, Kristi | Ardzinski, Andrzej | Stever, Kim | Dorsey, Bruce D. | Phelps, Janet R. | Lee, Amy C.H. | ... | Sofia, Michael J.
Bioorganic & Medicinal Chemistry Letters, volume 94 (2023).
10.1016/j.bmcl.2023.129456
Cited by (1) | Cite | Source
The identification of highly efficacious functionalised tetrahydrocyclopenta[ c ]pyrroles as inhibitors of HBV viral replication through modulation of HBV capsid assembly (journal article)
Cole, Andrew G. | Kultgen, Steven G. | Mani, Nagraj | Ardzinski, Andrzej | Fan, Kristi Yi | Thi, Emily P. | Dorsey, Bruce D. | Stever, Kim | Chiu, Tim | Tang, Sunny | ... | Sofia, Michael J.
RSC Medicinal Chemistry, volume 13, issue 3, pages 343-349 (2022).
10.1039/D1MD00318F
Cited by (4) | Cite | Source
Laboratory Notebooks and Data Storage (journal article)
Williams, Michael | Bozyczko‐Coyne, Donna | Dorsey, Bruce | Larsen, Scott | Powers, Chris | Gallagher, Sean
Current Protocols Essential Laboratory Techniques, volume 20, issue 1 (2020).
10.1002/cpet.42
Cite | Source
Azaquinazoline inhibitors of atypical protein kinase C (patent)
Dorsey, Bruce D. | Dugan, Benjamin J. | Fowler, Katherine M. | Hudkins, Robert L. | Mesaros, Eugen F. | Monck, Nathaniel J T | Morris, Emma L. | Olowoye, Ikeoluwa | Ott, Gregory R. | Pave, Gregoire A. | ... | Zulli, Allison L.
Patent Number: 10414763 (2019)
Cite | Source
Thienopyrimidine inhibitors of atypical protein kinase C (patent)
Dorsey, Bruce D. | Learn, Keith S. | Morris, Emma L. | Ott, Gregory R. | Roffey, Jonathan R. A. | Soudy, Christelle N. | Wagner, Jason C.
Patent Number: 10183950 (2019)
Cite | Source
Azaquinazoline inhibitors of Atypical protein Kinase C (patent)
Breslin, Henry J. | Dorsey, Bruce D. | Dugan, Benjamin J | Fowler, Katherine M. | Hudkins, Robert L | Mesaros, Eugen F. | Monck, Nathaniel J. T. | Morris, Emma L. | Olowoye, Ikeoluwa | Ott, Gregory R. | ... | Zulli, Allison L.
Patent Number: 9914730 (2018)
Cited by (2) | Cite | Source
1,4-substituted piperidine derivatives (patent)
Becknell, Nadine C. | Dandu, Reddeppa Reddy | Dorsey, Bruce D. | Gotchev, Dimitar B. | Hudkins, Robert L. | Weinberg, Linda | Zificsak, Craig A. | Zulli, Allison L.
Patent Number: 9902696 (2018)
Cited by (2) | Cite | Source
Azaquinazoline inhibitors of atypical protein kinase C (patent)
Breslin, Henry J. | Dorsey, Bruce D. | Dugan, Benjamin J. | Hudkins, Robert L. | Mesaros, Eugen F. | Ott, Gregory R. | Zificsak, Craig A. | Zulli, Allison L. | Tao, Ming | Fowler, Katherine M. | ... | Olowoye, Ikeoluwa
Patent Number: 9896446 (2018)
Cited by (1) | Cite | Source
Thienopyrimidine inhibitors of atypical protein kinase C (patent)
Dorsey, Bruce D | Learn, Keith S. | Morris, Emma L. | Ott, Gregory R | Roffey, Jonathan R. A. | Soudy, Christelle N. | Wagner, Jason C.
Patent Number: 9604994 (2017)
Cited by (3) | Cite | Source
Macrocyclic compounds as ALK, FAK and JAK2 inhibitors (patent)
Breslin, Henry J. | Dorsey, Bruce D. | Ott, Gregory R.
Patent Number: 9487529 (2016)
Cite | Source
Substituted aromatic sulfur compounds and methods of their use (patent)
Dorsey, Bruce D. | Kuwada, Scott K. | Theroff, Jay P. | Zificsak, Craig A.
Patent Number: 9475766 (2016)
Cite | Source
Discovery of Clinical Candidate CEP-37440, a Selective Inhibitor of Focal Adhesion Kinase (FAK) and Anaplastic Lymphoma Kinase (ALK) (journal article)
Ott, Gregory R. | Cheng, Mangeng | Learn, Keith S. | Wagner, Jason | Gingrich, Diane E. | Lisko, Joseph G. | Curry, Matthew | Mesaros, Eugen F. | Ghose, Arup K. | Quail, Matthew R. | ... | Dorsey, Bruce D.
Journal of Medicinal Chemistry, volume 59, issue 16, pages 7478-7496 (2016).
10.1021/acs.jmedchem.6b00487
Cited by (68) | Cite | Source
Piperidine-3,4-diol and piperidine-3-ol derivatives of pyrrolo[2,1-f][1,2,4]triazine as inhibitors of anaplastic lymphoma kinase (journal article)
Mesaros, Eugen F. | Angeles, Thelma S. | Albom, Mark S. | Wagner, Jason C. | Aimone, Lisa D. | Wan, Weihua | Lu, Lihui | Huang, Zeqi | Olsen, Mark | Kordwitz, Emily | ... | Ott, Gregory R.
Bioorganic & Medicinal Chemistry Letters, volume 25, issue 5, pages 1047-1052 (2015).
10.1016/j.bmcl.2015.01.019
Cited by (16) | Cite | Source
Design, Synthesis, and Biological Evaluation of Sulfonyl Acrylonitriles as Novel Inhibitors of Cancer Metastasis and Spread (journal article)
Shen, Yi | Zificsak, Craig A. | Shea, Jill E. | Lao, Xuegang | Bollt, Oana | Li, Xiufen | Lisko, Joseph G. | Theroff, Jay P. | Scaife, Courtney L. | Ator, Mark A. | ... | Kuwada, Scott K.
Journal of Medicinal Chemistry, volume 58, issue 3, pages 1140-1158 (2015).
10.1021/jm501437v
Cited by (26) | Cite | Source
Anaplastic lymphoma kinase inhibitors as anticancer therapeutics: a patent review (journal article)
Mesaros, Eugen F | Ott, Gregory R | Dorsey, Bruce D
Expert Opinion on Therapeutic Patents, volume 24, issue 4, pages 417-442 (2014).
10.1517/13543776.2014.877890
Cited by (26) | Cite | Source
Preparation and uses of 1,2,4-triazolo [1,5a] pyridine derivatives (patent)
Curry, Matthew A. | Dorsey, Bruce D. | Dugan, Benjamin J. | Gingrich, Diane E. | Mesaros, Eugen F. | Milkiewicz, Karen L.
Patent Number: 8633173 (2014)
Cited by (4) | Cite | Source
Fused bicyclic derivatives of 2,4-diaminopyrimidine as ALK and c-MET inhibitors (patent)
Dugan, Benjamin J. | Dorsey, Bruce D. | Zificsak, Craig A. | Feng, Daming | Gingrich, Diane E. | Mesaros, Eugen F. | Wells, Gregory J. | Ott, Gregory R. | Ahmed, Gulzar | Breslin, Henry J. | ... | Thieu, Tho
Patent Number: 8552186 (2013)
Cited by (17) | Cite | Source
Preparation and uses of 1,2,4-triazolo [1,5a] pyridine derivatives (patent)
Dugan, Benjamin J. | Dorsey, Bruce D. | Gingrich, Diane E. | Mesaros, Eugen F. | Milkiewicz, Karen L. | Curry, Matthew A.
Patent Number: 8501936 (2013)
Cited by (1) | Cite | Source
A Selective, Orally Bioavailable 1,2,4-Triazolo[1,5- a ]pyridine-Based Inhibitor of Janus Kinase 2 for Use in Anticancer Therapy: Discovery of CEP-33779 (journal article)
Dugan, Benjamin J. | Gingrich, Diane E. | Mesaros, Eugen F. | Milkiewicz, Karen L. | Curry, Matthew A. | Zulli, Allison L. | Dobrzanski, Pawel | Serdikoff, Cynthia | Jan, Mahfuza | Angeles, Thelma S. | ... | Dorsey, Bruce D.
Journal of Medicinal Chemistry, volume 55, issue 11, pages 5243-5254 (2012).
10.1021/jm300248q
Cited by (54) | Cite | Source