Margaret E. Brousseau

ScholarGPS® ID: 26612562527880

Affiliation
Novartis International AG, Basel, Switzerland
Affiliation History

Field
Medicine
Discipline
Cardiology
Top Specialties
Lipid | Metabolism | Coronary Artery Disease | Cholesteryl Ester | Atherosclerosis | High-density Lipoprotein
Metrics Summary
Publication Count
59
Predicted Citations
4,057
Predicted h-index
31
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Harnessing RNA Interference for Cholesterol Lowering: The Bench‐to‐Bedside Story of Inclisiran (journal article)
Wilkinson, Michael J. | Bajaj, Archna | Brousseau, Margaret E. | Taub, Pam R.
Journal of the American Heart Association, volume 13, issue 6 (2024).
10.1161/JAHA.123.032031
Cited by (2) | Cite | Source
Method of treating atherosclerosis in high triglyceride subjects (patent)
Arai, Yoshie | Brousseau, Margaret Elizabeth | Gu, Jessie | Hayashi, Tomoko | Mitani, Hironobu | Mogi, Muneto | Nonomura, Kazuhiko | Yamada, Ken
Patent Number: 9867811 (2018)
Cite | Source
Discovery of a Novel Piperidine-Based Inhibitor of Cholesteryl Ester Transfer Protein (CETP) That Retains Activity in Hypertriglyceridemic Plasma (journal article)
Yamada, Ken | Brousseau, Margaret | Honma, Wataru | Iimura, Akiko | Imase, Hidetomo | Iwaki, Yuki | Kawanami, Toshio | LaSala, Daniel | Liang, Guiqing | Mitani, Hironobu | ... | Mogi, Muneto
Journal of Medicinal Chemistry, volume 60, issue 20, pages 8466-8481 (2017).
10.1021/acs.jmedchem.7b00900
Cited by (6) | Cite | Source
Synthetic phospholipids as specific substrates for plasma endothelial lipase (journal article)
Papillon, Julien P.N. | Pan, Meihui | Brousseau, Margaret E. | Gilchrist, Mark A. | Lou, Changgang | Singh, Alok K. | Stawicki, Todd | Thompson, James E.
Bioorganic & Medicinal Chemistry Letters, volume 26, issue 15, pages 3514-3517 (2016).
10.1016/j.bmcl.2016.06.032
Cited by (3) | Cite | Source
Effects of CETP inhibition on triglyceride-rich lipoprotein composition and apoB-48 metabolism (journal article)
Diffenderfer, Margaret R. | Brousseau, Margaret E. | Millar, John S. | Barrett, P.Hugh R. | Nartsupha, Chorthip | Schaefer, Peter M. | Wolfe, Megan L. | Dolnikowski, Gregory G. | Rader, Daniel J. | Schaefer, Ernst J.
Journal of Lipid Research, volume 53, issue 6, pages 1190-1199 (2012).
10.1194/jlr.M019570
Cited by (14) | Cite | Source | Open Access
Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease (journal article)
Peloso, Gina M. | Demissie, Serkalem | Collins, Dorothea | Mirel, Daniel B. | Gabriel, Stacey B. | Cupples, L. Adrienne | Robins, Sander J. | Schaefer, Ernst J. | Brousseau, Margaret E.
Journal of Lipid Research, volume 51, issue 12, pages 3524-3532 (2010).
10.1194/jlr.P008268
Cited by (59) | Cite | Source | Open Access
Genetic Loci Influencing Plasma High Density Lipoprotein Cholesterol Concentrations in Humans (book chapter)
In High Density Lipoproteins, Dyslipidemia, and Coronary Heart Disease
Brousseau, Margaret E.
Springer New York (2010)
10.1007/978-1-4419-1059-2_14
Cite | Source
Effects of cholesteryl ester transfer protein inhibition on apolipoprotein A-II-containing HDL subspecies and apolipoprotein A-II metabolism (journal article)
Brousseau, Margaret E. | Millar, John S. | Diffenderfer, Margaret R. | Nartsupha, Chorthip | Asztalos, Bela F. | Wolfe, Megan L. | Mancuso, James P. | Digenio, Andres G. | Rader, Daniel J. | Schaefer, Ernst J.
Journal of Lipid Research, volume 50, issue 7, pages 1456-1462 (2009).
10.1194/jlr.P800037-JLR200
Cited by (19) | Cite | Source | Open Access
Effects of the cholesteryl ester transfer protein inhibitor torcetrapib on VLDL apolipoprotein E metabolism (journal article)
Millar, John S. | Brousseau, Margaret E. | Diffenderfer, Margaret R. | Barrett, P. Hugh R. | Welty, Francine K. | Cohn, Jeffrey S. | Wilson, Aisha | Wolfe, Megan L. | Nartsupha, Chorthip | Schaefer, Peter M. | ... | Rader, Daniel J.
Journal of Lipid Research, volume 49, issue 3, pages 543-549 (2008).
10.1194/jlr.M700268-JLR200
Cited by (14) | Cite | Source | Open Access
Codon 54 polymorphism of the fatty acid binding protein (FABP) 2 gene is associated with increased cardiovascular risk in the dyslipidemic diabetic participants of the veterans affairs HDL intervention trial (VA-HIT) (journal article)
Georgopoulos, Angeliki | Bloomfield, Hanna | Collins, Dorothea | Brousseau, Margaret E. | Ordovas, Jose M. | O’Connor, John J. | Robins, Sander J. | Schaefer, Ernest J.
Atherosclerosis, volume 194, issue 1, pages 169-174 (2007).
10.1016/j.atherosclerosis.2006.07.022
Cited by (20) | Cite | Source
The L162V polymorphism at the peroxisome proliferator activated receptor alpha locus modulates the risk of cardiovascular events associated with insulin resistance and diabetes mellitus: The Veterans Affairs HDL Intervention Trial (VA-HIT) (journal article)
Tai, E. Shyong | Collins, Dorothea | Robins, Sander J. | O’Connor, John J. | Bloomfield, Hanna E. | Ordovas, Jose M. | Schaefer, Ernst J. | Brousseau, Margaret E.
Atherosclerosis, volume 187, issue 1, pages 153-160 (2006).
10.1016/j.atherosclerosis.2005.08.034
Cited by (35) | Cite | Source
Association of obesity with variations at selected gene loci (journal article)
McDermott, Ann Yelmokas | Kirkendall, Rosanna | Brousseau, Margaret E. | Parnell, Larry | Polisecki, Eliana Y. | Schaefer, Ernst J.
The FASEB Journal, volume 20, issue 5 (2006).
10.1096/fasebj.20.5.A1036-a
Cite | Source
Mo-W1:1 Effects of cholesteryl ester transfer protein inhibition on lipoprotein metabolism in humans (journal article)
Brousseau, M.E. | Diffenderfer, M.R. | Millar, J.S. | Nartsupha, C. | Asztalos, B.F. | Welty, F.K. | Wolfe, M.L. | Mancuso, J.P. | Digenio, A.G. | Rader, D.J. | Schaefer, E.J.
Atherosclerosis Supplements, volume 7, issue 3, pages 11- (2006).
10.1016/S1567-5688(06)80023-1
Cite | Source
Emerging role of high-density lipoprotein in the prevention of cardiovascular disease (journal article)
Brousseau, Margaret E.
Drug Discovery Today, volume 10, issue 16, pages 1095-1101 (2005).
10.1016/S1359-6446(05)03514-2
Cited by (24) | Cite | Source
A promoter polymorphism in cholesterol 7α-hydroxylase interacts with apolipoprotein E genotype in the LDL-lowering response to atorvastatin (journal article)
Kajinami, Kouji | Brousseau, Margaret E. | Ordovas, Jose M. | Schaefer, Ernst J.
Atherosclerosis, volume 180, issue 2, pages 407-415 (2005).
10.1016/j.atherosclerosis.2004.12.019
Cited by (54) | Cite | Source
Cholesteryl ester transfer protein inhibition and the treatment of metabolic syndrome (journal article)
Clark, Ronald W. | Brousseau, Margaret E.
Drug Discovery Today: Therapeutic Strategies, volume 2, issue 2, pages 117-124 (2005).
10.1016/j.ddstr.2005.05.004
Cited by (3) | Cite | Source
Effects of Cholesteryl Ester Transfer Protein Inhibition on High-Density Lipoprotein Subspecies, Apolipoprotein A-I Metabolism, and Fecal Sterol Excretion (journal article)
Brousseau, Margaret E. | Diffenderfer, Margaret R. | Millar, John S. | Nartsupha, Chorthip | Asztalos, Bela F. | Welty, Francine K. | Wolfe, Megan L. | Rudling, Mats | Björkhem, Ingemar | Angelin, Bo | ... | Schaefer, Ernst J.
Arteriosclerosis, Thrombosis, and Vascular Biology, volume 25, issue 5, pages 1057-1064 (2005).
10.1161/01.ATV.0000161928.16334.dd
Cited by (216) | Cite | Source | Open Access
Gender-specific effects of estrogen receptor α gene haplotype on high-density lipoprotein cholesterol response to atorvastatin: interaction with apolipoprotein AI gene polymorphism (journal article)
Kajinami, Kouji | Brousseau, Margaret E. | Lamon-Fava, Stefania | Ordovas, Jose M. | Schaefer, Ernst J.
Atherosclerosis, volume 178, issue 2, pages 331-338 (2005).
10.1016/j.atherosclerosis.2004.08.034
Cited by (34) | Cite | Source
Common Variation in Genes Involved in HDL Metabolism Influences Coronary Heart Disease Risk at the Population Level (journal article)
Brousseau, Margaret E.
Reviews in Endocrine and Metabolic Disorders, volume 5, issue 4, pages 343-349 (2004).
10.1023/B:REMD.0000045106.90301.26
Cited by (4) | Cite | Source
Pharmacogenetics of HMG-CoA reductase inhibitors: exploring the potential for genotype-based individualization of coronary heart disease management (journal article)
Kajinami, Kouji | Takekoshi, Noboru | Brousseau, Margaret E. | Schaefer, Ernst J.
Atherosclerosis, volume 177, issue 2, pages 219-234 (2004).
10.1016/j.atherosclerosis.2004.09.004
Cited by (72) | Cite | Source