Dana L. Johnson

ScholarGPS® ID: 26429833727888

Affiliation
Johnson & Johnson, New Brunswick, New Jersey, United States
Affiliation History

Field
Medicine
Discipline
Cardiology
Top Specialties
Medicinal Chemistry | Protein Kinase Inhibitor | Chemical Synthesis | Cancer | Growth Factor Receptor
Metrics Summary
Publication Count
42
Predicted Citations
1,770
Predicted h-index
22
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Discovery of Orally Efficacious Tetrahydrobenzimidazoles as TGR5 Agonists for Type 2 Diabetes (journal article)
Zhang, Xuqing | Wall, Mark | Sui, Zhihua | Kauffman, Jack | Hou, Cuifen | Chen, Cailin | Du, Fuyong | Kirchner, Thomas | Liang, Yin | Johnson, Dana L. | ... | Demarest, Keith
ACS Medicinal Chemistry Letters, volume 8, issue 5, pages 560-565 (2017).
10.1021/acsmedchemlett.7b00116
Cited by (8) | Cite | Source | Open Access
Evaluation of anti-diabetic effect and gall bladder function with 2-thio-5-thiomethyl substituted imidazoles as TGR5 receptor agonists (journal article)
Zhang, Xuqing | Sui, Zhihua | Kauffman, Jack | Hou, Cuifen | Chen, Cailin | Du, Fuyong | Kirchner, Thomas | Liang, Yin | Johnson, Dana | Murray, William V. | Demarest, Keith
Bioorganic & Medicinal Chemistry Letters, volume 27, issue 8, pages 1760-1764 (2017).
10.1016/j.bmcl.2017.02.069
Cited by (15) | Cite | Source
The discovery and SAR of cyclopenta[b]furans as inhibitors of CCR2 (journal article)
Winters, Michael P. | Teleha, Christopher A. | Kang, Fu-An | McComsey, David | O’Neill, John C. | Hou, Cuifen | Kirchner, Thomas | Wang, Ping | Johnson, Dana | Sui, Zhihua
Bioorganic & Medicinal Chemistry Letters, volume 24, issue 9, pages 2137-2140 (2014).
10.1016/j.bmcl.2014.03.036
Cited by (5) | Cite | Source
Discovery and SAR of 5-aminooctahydrocyclopentapyrrole-3a-carboxamides as potent CCR2 antagonists (journal article)
Cai, Chaozhong | McComsey, Dave F. | Hou, Cuifen | O’Neill, John C. | Opas, Evan | McKenney, Sandra | Johnson, Dana | Sui, Zhihua
Bioorganic & Medicinal Chemistry Letters, volume 24, issue 4, pages 1239-1242 (2014).
10.1016/j.bmcl.2013.05.024
Cited by (6) | Cite | Source
A novel series of N-(azetidin-3-yl)-2-(heteroarylamino)acetamide CCR2 antagonists (journal article)
Subasinghe, Nalin L. | Lanter, James | Markotan, Thomas | Opas, Evan | McKenney, Sandra | Crysler, Carl | Hou, Cuifen | O’Neill, John | Johnson, Dana | Sui, Zhihua
Bioorganic & Medicinal Chemistry Letters, volume 23, issue 4, pages 1063-1069 (2013).
10.1016/j.bmcl.2012.12.017
Cited by (19) | Cite | Source
Novel 2-aminooctahydrocyclopentalene-3a-carboxamides as potent CCR2 antagonists (journal article)
Cai, Chaozhong | Kang, Fu-An | Hou, Cuifen | O’Neill, John C. | Opas, Evan | McKenney, Sandra | Johnson, Dana | Sui, Zhihua
Bioorganic & Medicinal Chemistry Letters, volume 23, issue 1, pages 351-354 (2013).
10.1016/j.bmcl.2012.10.069
Cited by (7) | Cite | Source
Discovery of a 4-Azetidinyl-1-thiazoyl-cyclohexane CCR2 Antagonist as a Development Candidate (journal article)
Zhang, Xuqing | Hou, Cuifen | Hufnagel, Heather | Singer, Monica | Opas, Evan | McKenney, Sandra | Johnson, Dana | Sui, Zhihua
ACS Medicinal Chemistry Letters, volume 3, issue 12, pages 1039-1044 (2012).
10.1021/ml300260s
Cited by (17) | Cite | Source | Open Access
Oral Coadministration of β-Glucuronidase to Increase Exposure of Extensively Glucuronidated Drugs that Undergo Enterohepatic Recirculation (journal article)
Eichenbaum, Gary | Hsu, C.-P. | Subrahmanyam, Vangala | Chen, Jing | Scicinski, Jan | Galemmo, Robert A. | Tuman, Robert W. | Johnson, Dana L.
Journal of Pharmaceutical Sciences, volume 101, issue 7, pages 2545-2556 (2012).
10.1002/jps.23113
Cited by (8) | Cite | Source
The discovery of novel cyclohexylamide CCR2 antagonists (journal article)
Lanter, James C. | Markotan, Thomas P. | Zhang, Xuqing | Subasinghe, Nalin | Kang, Fu-An | Hou, Cuifen | Singer, Monica | Opas, Evan | McKenney, Sandra | Crysler, Carl | ... | Sui, Zhihua
Bioorganic & Medicinal Chemistry Letters, volume 21, issue 24, pages 7496-7501 (2011).
10.1016/j.bmcl.2011.09.113
Cited by (9) | Cite | Source
Design, synthesis and SAR of indazole and benzoisoxazole containing 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists (journal article)
Zhang, Xuqing | Hufnagel, Heather | Hou, Cuifen | Opas, Evan | McKenney, Sandra | Crysler, Carl | O’Neill, John | Johnson, Dana | Sui, Zhihua
Bioorganic & Medicinal Chemistry Letters, volume 21, issue 20, pages 6042-6048 (2011).
10.1016/j.bmcl.2011.08.074
Cited by (12) | Cite | Source
Matrix Metalloproteinase-9 Inhibition Reduces Inflammation and Improves Motility in Murine Models of Postoperative Ileus (journal article)
Moore, Beverley A. | Manthey, Carl L. | Johnson, Dana L. | Bauer, Anthony J.
Gastroenterology, volume 141, issue 4, pages 1283-1292.e4 (2011).
10.1053/j.gastro.2011.06.035
Cited by (46) | Cite | Source | Open Access
Overcoming hERG activity in the discovery of a series of 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists (journal article)
Zhang, Xuqing | Hufnagel, Heather | Markotan, Thomas | Lanter, James | Cai, Chaozhong | Hou, Cuifen | Singer, Monica | Opas, Evan | McKenney, Sandra | Crysler, Carl | ... | Sui, Zhihua
Bioorganic & Medicinal Chemistry Letters, volume 21, issue 18, pages 5577-5582 (2011).
10.1016/j.bmcl.2011.06.080
Cited by (19) | Cite | Source
GLP-2 Receptor Agonism Ameliorates Inflammation and Gastrointestinal Stasis in Murine Postoperative Ileus (journal article)
Moore, B. A. | Peffer, N. | Pirone, A. | Bassiri, A. | Sague, S. | Palmer, J. M. | Johnson, D. L. | Nesspor, T. | Kliwinski, C. | Hornby, P. J.
Journal of Pharmacology and Experimental Therapeutics, volume 333, issue 2, pages 574-583 (2010).
10.1124/jpet.109.161497
Cited by (27) | Cite | Source | Open Access
JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia (journal article)
Manthey, Carl L. | Johnson, Dana L. | Illig, Carl R. | Tuman, Robert W. | Zhou, Zhao | Baker, Judith F. | Chaikin, Margery A. | Donatelli, Robert R. | Franks, Carol F. | Zeng, Lee | ... | Molloy, Christopher J.
Molecular Cancer Therapeutics, volume 8, issue 11, pages 3151-3161 (2009).
10.1158/1535-7163.MCT-09-0255
Cited by (96) | Cite | Source | Open Access
Studies with an Orally Bioavailable αV Integrin Antagonist in Animal Models of Ocular Vasculopathy: Retinal Neovascularization in Mice and Retinal Vascular Permeability in Diabetic Rats (journal article)
Santulli, Rosemary J. | Kinney, William A. | Ghosh, Shyamali | DeCorte, Bart L. | Liu, Li | Tuman, Robert W. A. | Zhou, Zhao | Huebert, Norman | Bursell, Sven E. | Clermont, Alan C. | ... | Damiano, Bruce P.
Journal of Pharmacology and Experimental Therapeutics, volume 324, issue 3, pages 894-901 (2008).
10.1124/jpet.107.131656
Cited by (59) | Cite | Source | Open Access
R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoral activity against solid and haematological malignancies (journal article)
Arts, J | Angibaud, P | Mariën, A | Floren, W | Janssens, B | King, P | van Dun, J | Janssen, L | Geerts, T | Tuman, R W | ... | van Emelen, K
British Journal of Cancer, volume 97, issue 10, pages 1344-1353 (2007).
10.1038/sj.bjc.6604025
Cited by (78) | Cite | Source | Open Access
Progress in the Development of Agents to Control the Cell Cycle (book chapter)
In Cancer
Moriarty, Kevin J. | Koblish, Holly | Johnson, Dana L. | Galemmo, Robert A.
Springer Berlin Heidelberg (2007)
10.1007/7355_2006_006
Cited by (6) | Cite | Source
The synthesis and SAR of 2-amino-pyrrolo[2,3-d]pyrimidines: A new class of Aurora-A kinase inhibitors (journal article)
Moriarty, Kevin J. | Koblish, Holly K. | Garrabrant, Thomas | Maisuria, Jahanvi | Khalil, Ehab | Ali, Farah | Petrounia, Ioanna P. | Crysler, Carl S. | Maroney, Anna C. | Johnson, Dana L. | Galemmo, Robert A.
Bioorganic & Medicinal Chemistry Letters, volume 16, issue 22, pages 5778-5783 (2006).
10.1016/j.bmcl.2006.08.080
Cited by (93) | Cite | Source
Dihydroquinone Ansamycins: Toward Resolving the Conflict between Low in Vitro Affinity and High Cellular Potency of Geldanamycin Derivatives (journal article)
Maroney, Anna C. | Marugan, Juan J. | Mezzasalma, Tara M. | Barnakov, Alexander N. | Garrabrant, Thomas A. | Weaner, Larry E. | Jones, William J. | Barnakova, Ludmila A. | Koblish, Holly K. | Todd, Matthew J. | ... | Johnson, Dana L.
Biochemistry, volume 45, issue 17, pages 5678-5685 (2006).
10.1021/bi0524969
Cited by (53) | Cite | Source
N -GLUCURONIDATION OF THE PLATELET-DERIVED GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITOR 6,7-(DIMETHOXY-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)-(3-FLUORO-PHENYL)-AMINE BY HUMAN UDP-GLUCURONOSYLTRANSFERASES (journal article)
Yan, Z. | Caldwell, G. W. | Gauthier, D. | Leo, G. C. | Mei, J. | Ho, C. Y. | Jones, W. J. | Masucci, J. A. | Tuman, R. W. | Galemmo, R. A. | Johnson, D. L.
Drug Metabolism and Disposition, volume 34, issue 5, pages 748-755 (2006).
10.1124/dmd.106.009274
Cited by (28) | Cite | Source | Open Access