Rajkumar Ganesan

ScholarGPS® ID: 25550846760161

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Life Sciences

Discipline

Biochemistry

Top Specialties

Antibody | Cancer | Serine Protease | Bispecific Monoclonal Antibody

Metrics Summary

Publication Count

Predicted Citations

1,806

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Conduit CAR: Redirecting CAR T-Cell Specificity with A Universal and Adaptable Bispecific Antibody Platform (journal article) Borrok, M. Jack \| Li, Yonghai \| Harvilla, Paul B. \| Vellalore Maruthachalam, Bharathikumar \| Tamot, Ninkka \| Prokopowitz, Christine \| Chen, Jun \| Venkataramani, Sathya \| Grewal, Iqbal S. \| Ganesan, Rajkumar \| Singh, Sanjaya Cancer Research Communications, volume 2, issue 3, pages 146-157 (2022). 10.1158/2767-9764.CRC-21-0150 Cited by (3) \| Cite \| Source
A Novel Antagonistic CD73 Antibody for Inhibition of the Immunosuppressive Adenosine Pathway (journal article) Wurm, Melanie \| Schaaf, Otmar \| Reutner, Katharina \| Ganesan, Rajkumar \| Mostböck, Sven \| Pelster, Christina \| Böttcher, Jark \| de Andrade Pereira, Bruna \| Taubert, Christina \| Alt, Isabella \| ... \| Hofmann, Irmgard Molecular Cancer Therapeutics, volume 20, issue 11, pages 2250-2261 (2021). 10.1158/1535-7163.MCT-21-0107 Cited by (12) \| Cite \| Source
Selective recruitment of γδ T cells by a bispecific antibody for the treatment of acute myeloid leukemia (journal article) Ganesan, Rajkumar \| Chennupati, Vijaykumar \| Ramachandran, Balaji \| Hansen, Michael Riis \| Singh, Sanjaya \| Grewal, Iqbal S. Leukemia, volume 35, issue 8, pages 2274-2284 (2021). 10.1038/s41375-021-01122-7 Cited by (39) \| Cite \| Source
Bispecific Antibodies for Triple Negative Breast Cancer (journal article) Dees, Sundee \| Ganesan, Rajkumar \| Singh, Sanjaya \| Grewal, Iqbal S. Trends in Cancer, volume 7, issue 2, pages 162-173 (2021). 10.1016/j.trecan.2020.09.004 Cited by (33) \| Cite \| Source
Regulatory T cell targeting in cancer: Emerging strategies in immunotherapy (journal article) Dees, Sundee \| Ganesan, Rajkumar \| Singh, Sanjaya \| Grewal, Iqbal S. European Journal of Immunology, volume 51, issue 2, pages 280-291 (2021). 10.1002/eji.202048992 Cited by (74) \| Cite \| Source
Emerging CAR-T Cell Therapy for the Treatment of Triple-Negative Breast Cancer (journal article) Dees, Sundee \| Ganesan, Rajkumar \| Singh, Sanjaya \| Grewal, Iqbal S. Molecular Cancer Therapeutics, volume 19, issue 12, pages 2409-2421 (2020). 10.1158/1535-7163.MCT-20-0385 Cited by (64) \| Cite \| Source
Preclinical efficacy of humanized, non–FcγR-binding anti-CD3 antibodies in T-cell acute lymphoblastic leukemia (journal article) Tran Quang, Christine \| Zaniboni, Benedetta \| Humeau, Romain \| Lengliné, Etienne \| Dourthe, Marie Emilie \| Ganesan, Rajkumar \| Singh, Sanjaya \| Scheer, Justin M. \| Asnafi, Vahid \| Ghysdael, Jacques Blood, volume 136, issue 11, pages 1298-1302 (2020). 10.1182/blood.2019003801 Cited by (8) \| Cite \| Source
In Pursuit of Stability Enhancement of a Prostate Cancer Targeting Antibody Derived from a Transgenic Animal Platform (journal article) Venkataramani, Sathya \| Ernst, Robin \| Derebe, Mehabaw Getahun \| Wright, Robert \| Kopenhaver, Jessica \| Jacobs, Steven A. \| Singh, Sanjaya \| Ganesan, Rajkumar Scientific Reports, volume 10, issue 1 (2020). 10.1038/s41598-020-66636-z Cited by (6) \| Cite \| Source
High-Throughput Generation of Bipod (Fab × scFv) Bispecific Antibodies Exploits Differential Chain Expression and Affinity Capture (journal article) Nesspor, Thomas C. \| Kinealy, Kyle \| Mazzanti, Nicholas \| Diem, Michael D. \| Boye, Kevin \| Hoffman, Hunter \| Springer, Christine \| Sprenkle, Justin \| Powers, Gordon \| Jiang, Haiyan \| ... \| Zwolak, Adam Scientific Reports, volume 10, issue 1 (2020). 10.1038/s41598-020-64536-w Cited by (11) \| Cite \| Source
Discovery and characterization of single-domain antibodies for polymeric Ig receptor-mediated mucosal delivery of biologics (journal article) Maruthachalam, Bharathikumar Vellalore \| Zwolak, Adam \| Lin-Schmidt, Xiefan \| Keough, Edward \| Tamot, Ninkka \| Venkataramani, Sathya \| Geist, Brian \| Singh, Sanjaya \| Ganesan, Rajkumar mAbs, volume 12, issue 1 (2020). 10.1080/19420862.2019.1708030 Cited by (7) \| Cite \| Source
Retrospective analysis of model-based predictivity of human pharmacokinetics for anti-IL-36R monoclonal antibody MAB92 using a rat anti-mouse IL-36R monoclonal antibody and RNA expression data (FANTOM5) (journal article) Ahlberg, Jennifer \| Giragossian, Craig \| Li, Hua \| Myzithras, Maria \| Raymond, Ernie \| Caviness, Gary \| Grimaldi, Christine \| Brown, Su-Ellen \| Perez, Rocio \| Yang, Danlin \| ... \| Mbow, M. Lamine mAbs, volume 11, issue 5, pages 956-964 (2019). 10.1080/19420862.2019.1615345 Cited by (6) \| Cite \| Source
Design and characterization of Zweimab and Doppelmab, high affinity dual antagonistic anti-TSLP/IL13 bispecific antibodies (journal article) Venkataramani, Sathyadevi \| Low, Sarah \| Weigle, Bernd \| Dutcher, Darrin \| Jerath, Kavita \| Menzenski, Monica \| Frego, Lee \| Truncali, Kris \| Gupta, Pankaj \| Kroe-Barrett, Rachel \| ... \| Erb, Klaus J. Biochemical and Biophysical Research Communications, volume 504, issue 1, pages 19-24 (2018). 10.1016/j.bbrc.2018.08.064 Cited by (39) \| Cite \| Source
Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies (journal article) Ganesan, Rajkumar \| Raymond, Ernest L. \| Mennerich, Detlev \| Woska, Joseph R. \| Caviness, Gary \| Grimaldi, Christine \| Ahlberg, Jennifer \| Perez, Rocio \| Roberts, Simon \| Yang, Danlin \| ... \| Mbow, M. Lamine mAbs, volume 9, issue 7, pages 1143-1154 (2017). 10.1080/19420862.2017.1353853 Cited by (71) \| Cite \| Source \| Open Access
Multi-specific binding proteins (patent) Ganesan, Rajkumar \| Singh, Sanjaya \| Shaaban, Abdulsalam Patent Number: 20170002097 (2017) Cite \| Source
Structural and Functional Attributes of the Interleukin-36 Receptor (journal article) Yi, Guanghui \| Ybe, Joel A. \| Saha, Siddhartha S. \| Caviness, Gary \| Raymond, Ernest \| Ganesan, Rajkumar \| Mbow, M. Lamine \| Kao, C. Cheng Journal of Biological Chemistry, volume 291, issue 32, pages 16597-16609 (2016). 10.1074/jbc.M116.723064 Cited by (38) \| Cite \| Source \| Open Access
Signal Transduction and Intracellular Trafficking by the Interleukin 36 Receptor (journal article) Saha, Siddhartha S. \| Singh, Divyendu \| Raymond, Ernest L. \| Ganesan, Rajkumar \| Caviness, Gary \| Grimaldi, Christine \| Woska, Joseph R. \| Mennerich, Detlev \| Brown, Su-Ellen \| Mbow, M. Lamine \| Kao, C. Cheng Journal of Biological Chemistry, volume 290, issue 39, pages 23997-24006 (2015). 10.1074/jbc.M115.653378 Cited by (25) \| Cite \| Source \| Open Access
Modulators of hepatocyte growth factor activator (patent) Ganesan, Rajkumar \| Kirchhofer, Daniel Patent Number: 8759491 (2014) Cite \| Source
Methods and compositions for modulating hepsin activation of macrophage-stimulating protein (patent) Ganesan, Rajkumar \| Kirchhofer, Daniel Patent Number: 8697386 (2014) Cite \| Source
Anti-hepsin antibodies and methods using same (patent) Kirchhofer, Daniel \| Moran, Paul M. \| Ganesan, Rajkumar \| Zhang, Yingnan Patent Number: 8435511 (2013) Cited by (3) \| Cite \| Source
Mutational Tail Loss Is an Evolutionary Mechanism for Liberating Marapsins and Other Type I Serine Proteases from Transmembrane Anchors (journal article) Raman, Kavita \| Trivedi, Neil N. \| Raymond, Wilfred W. \| Ganesan, Rajkumar \| Kirchhofer, Daniel \| Verghese, George M. \| Craik, Charles S. \| Schneider, Eric L. \| Nimishakavi, Shilpa \| Caughey, George H. Journal of Biological Chemistry, volume 288, issue 15, pages 10588-10598 (2013). 10.1074/jbc.M112.449033 Cited by (5) \| Cite \| Source \| Open Access