Dana Hocková

ScholarGPS® ID: 24852141747251

Affiliation

Czech Academy of Sciences, Prague, Czechia

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

2,295

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Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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N2′‐Branched Acyclic Nucleoside Phosphonates Containing 9‐Deazahypoxanthine as Inhibitors of Plasmodium falciparum 6‐Oxopurine Phosphoribosyltransferase (journal article) Vaňková, Karolína \| Keough, Dianne T. \| Hocková, Dana \| Guddat, Luke W. \| Janeba, Zlatko ChemMedChem, volume 18, issue 15 (2023). 10.1002/cmdc.202300211 Cite \| Source
Synthesis and anti-trypanosomal evaluation of novel N-branched acyclic nucleoside phosphonates bearing 7-aryl-7-deazapurine nucleobase (journal article) Vaňková, Karolína \| Doleželová, Eva \| Tloušťová, Eva \| Hocková, Dana \| Zíková, Alena \| Janeba, Zlatko European Journal of Medicinal Chemistry, volume 239 (2022). 10.1016/j.ejmech.2022.114559 Cited by (3) \| Cite \| Source
Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6-Oxopurine Phosphoribosyltransferases (journal article) Klejch, Tomáš \| Keough, Dianne T. \| King, Gordon \| Doleželová, Eva \| Česnek, Michal \| Buděšínský, Miloš \| Zíková, Alena \| Janeba, Zlatko \| Guddat, Luke W. \| Hocková, Dana Journal of Medicinal Chemistry, volume 65, issue 5, pages 4030-4057 (2022). 10.1021/acs.jmedchem.1c01881 Cited by (5) \| Cite \| Source
C1′-Branched acyclic nucleoside phosphonates mimicking adenosine monophosphate: Potent inhibitors of Trypanosoma brucei adenine phosphoribosyltransferase (journal article) Kalčic, Filip \| Frydrych, Jan \| Doleželová, Eva \| Slapničková, Martina \| Pachl, Petr \| Slavětínská, Lenka Poštová \| Dračínský, Martin \| Hocková, Dana \| Zíková, Alena \| Janeba, Zlatko European Journal of Medicinal Chemistry, volume 225 (2021). 10.1016/j.ejmech.2021.113798 Cited by (3) \| Cite \| Source
Nucleotide analogues containing a pyrrolidine, piperidine or piperazine ring: Synthesis and evaluation of inhibition of plasmodial and human 6-oxopurine phosphoribosyltransferases and in vitro antimalarial activity (journal article) Frydrych, Jan \| Keough, Dianne T. \| Chavchich, Marina \| Travis, Jye \| Dračínský, Martin \| Edstein, Michael D. \| Guddat, Luke W. \| Hocková, Dana \| Janeba, Zlatko European Journal of Medicinal Chemistry, volume 219 (2021). 10.1016/j.ejmech.2021.113416 Cited by (9) \| Cite \| Source
Acyclic nucleoside phosphonates with adenine nucleobase inhibit Trypanosoma brucei adenine phosphoribosyltransferase in vitro (journal article) Doleželová, Eva \| Klejch, Tomáš \| Špaček, Petr \| Slapničková, Martina \| Guddat, Luke \| Hocková, Dana \| Zíková, Alena Scientific Reports, volume 11, issue 1 (2021). 10.1038/s41598-021-91747-6 Cited by (7) \| Cite \| Source
Helicobacter pylori Xanthine–Guanine–Hypoxanthine Phosphoribosyltransferase—A Putative Target for Drug Discovery against Gastrointestinal Tract Infections (journal article) Keough, Dianne T. \| Wun, Shun Jie \| Baszczyňski, Ondřej \| Eng, Wai Soon \| Špaček, Petr \| Panjikar, Santosh \| Naesens, Lieve \| Pohl, Radek \| Rejman, Dominik \| Hocková, Dana \| ... \| Guddat, Luke W. Journal of Medicinal Chemistry, volume 64, issue 9, pages 5710-5729 (2021). 10.1021/acs.jmedchem.0c02184 Cited by (5) \| Cite \| Source
Hypoxanthine-Guanine Phosphoribosyltransferase Is Dispensable for Mycobacterium smegmatis Viability (journal article) Knejzlík, Zdeněk \| Herkommerová, Klára \| Hocková, Dana \| Pichová, Iva Journal of Bacteriology, volume 202, issue 5 (2020). 10.1128/JB.00710-19 Cited by (4) \| Cite \| Source
Crystal structures of Trypanosoma brucei hypoxanthine – guanine – xanthine phosphoribosyltransferase in complex with IMP , GMP and XMP (journal article) Terán, David \| Doleželová, Eva \| Keough, Dianne T. \| Hocková, Dana \| Zíková, Alena \| Guddat, Luke W. The FEBS Journal, volume 286, issue 23, pages 4721-4736 (2019). 10.1111/febs.14987 Cited by (9) \| Cite \| Source
Sulfide, sulfoxide and sulfone bridged acyclic nucleoside phosphonates as inhibitors of the Plasmodium falciparum and human 6-oxopurine phosphoribosyltransferases: Synthesis and evaluation (journal article) Klejch, Tomáš \| Keough, Dianne T. \| Chavchich, Marina \| Travis, Jye \| Skácel, Jan \| Pohl, Radek \| Janeba, Zlatko \| Edstein, Michael D. \| Avery, Vicky M. \| Guddat, Luke W. \| Hocková, Dana European Journal of Medicinal Chemistry, volume 183 (2019). 10.1016/j.ejmech.2019.111667 Cited by (13) \| Cite \| Source
Acyclic nucleoside phosphonates with unnatural nucleobases, favipiravir and allopurinol, designed as potential inhibitors of the human and Plasmodium falciparum 6-oxopurine phosphoribosyltransferases (journal article) Klejch, Tomáš \| Pohl, Radek \| Janeba, Zlatko \| Sun, Minghan \| Keough, Dianne T. \| Guddat, Luke W. \| Hocková, Dana Tetrahedron, volume 74, issue 40, pages 5886-5897 (2018). 10.1016/j.tet.2018.08.014 Cited by (11) \| Cite \| Source
Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery. (journal article) Dolezelova, Eva \| Terán, David \| Gahura, Ondřej \| Kotrbova, Z \| Prochazkova, M \| Keough, Dianne T. \| Špaček, Petr \| Hocková, Dana \| Guddat, Luke W. \| Zíková, Alena PLOS Neglected Tropical Diseases, volume 12, issue 2, pages 1-28 (2018). 10.2210/pdb6apv/pdb Cited by (3) \| Cite \| Source
Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery (journal article) Doleželová, Eva \| Terán, David \| Gahura, Ondřej \| Kotrbová, Zuzana \| Procházková, Michaela \| Keough, Dianne \| Špaček, Petr \| Hocková, Dana \| Guddat, Luke \| Zíková, Alena PLOS Neglected Tropical Diseases, volume 12, issue 2, pages e0006301- (2018). 10.1371/journal.pntd.0006301 Cited by (33) \| Cite \| Source \| Open Access
Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics (journal article) Keough, Dianne T. \| Rejman, Dominik \| Pohl, Radek \| Zborníková, Eva \| Hocková, Dana \| Croll, Tristan \| Edstein, Michael D. \| Birrell, Geoff W. \| Chavchich, Marina \| Naesens, Lieve M. J. \| ... \| Guddat, Luke W. ACS Chemical Biology, volume 13, issue 1, pages 82-90 (2018). 10.1021/acschembio.7b00916 Cited by (22) \| Cite \| Source
Synthesis and Evaluation of Asymmetric Acyclic Nucleoside Bisphosphonates as Inhibitors of Plasmodium falciparum and Human Hypoxanthine–Guanine–(Xanthine) Phosphoribosyltransferase (journal article) Špaček, Petr \| Keough, Dianne T. \| Chavchich, Marina \| Dračínský, Martin \| Janeba, Zlatko \| Naesens, Lieve \| Edstein, Michael D. \| Guddat, Luke W. \| Hocková, Dana Journal of Medicinal Chemistry, volume 60, issue 17, pages 7539-7554 (2017). 10.1021/acs.jmedchem.7b00926 Cited by (17) \| Cite \| Source
Synthesis and evaluation of symmetric acyclic nucleoside bisphosphonates as inhibitors of the Plasmodium falciparum, Plasmodium vivax and human 6-oxopurine phosphoribosyltransferases and the antimalarial activity of their prodrugs (journal article) Špaček, Petr \| Keough, Dianne T. \| Chavchich, Marina \| Dračínský, Martin \| Janeba, Zlatko \| Naesens, Lieve \| Edstein, Michael D. \| Guddat, Luke W. \| Hocková, Dana Bioorganic & Medicinal Chemistry, volume 25, issue 15, pages 4008-4030 (2017). 10.1016/j.bmc.2017.05.048 Cited by (20) \| Cite \| Source
Acyclic Nucleoside Phosphonates Containing 9‐Deazahypoxanthine and a Five‐Membered Heterocycle as Selective Inhibitors of Plasmodial 6‐Oxopurine Phosphoribosyltransferases (journal article) Kaiser, Martin Maxmilian \| Baszczyňski, Ondřej \| Hocková, Dana \| Poštová‐Slavětínská, Lenka \| Dračínský, Martin \| Keough, Dianne T. \| Guddat, Luke W. \| Janeba, Zlatko ChemMedChem, volume 12, issue 14, pages 1133-1141 (2017). 10.1002/cmdc.201700293 Cited by (21) \| Cite \| Source
Oligomeric state of hypoxanthine−guanine phosphoribosyltransferase from Mycobacterium tuberculosis (journal article) Eng, Wai Soon \| Keough, Dianne T. \| Hockova, Dana \| Winzor, Donald J. \| Guddat, Luke W. Biochimie, volume 135 (2017). 10.1016/j.biochi.2016.12.020 Cited by (9) \| Cite \| Source \| Open Access
Novel nucleotide analogues bearing (1 H -1,2,3-triazol-4-yl)phosphonic acid moiety as inhibitors of Plasmodium and human 6-oxopurine phosphoribosyltransferases (journal article) Lukáč, Miloš \| Hocková, Dana \| Keough, Dianne T. \| Guddat, Luke W. \| Janeba, Zlatko Tetrahedron, volume 73, issue 6, pages 692-702 (2017). 10.1016/j.tet.2016.12.046 Cited by (13) \| Cite \| Source \| Open Access
Crystal Structures of Acyclic Nucleoside Phosphonates in Complex with Escherichia coli Hypoxanthine Phosphoribosyltransferase (journal article) Eng, Wai Soon \| Hocková, Dana \| Špaček, Petr \| Baszczyňski, Ondřej \| Janeba, Zlatko \| Naesens, Lieve \| Keough, Dianne T. \| Guddat, Luke W. ChemistrySelect, volume 1, issue 19, pages 6267-6276 (2016). 10.1002/slct.201601679 Cited by (10) \| Cite \| Source