Gregory Z. Ferl

ScholarGPS® ID: 24537247517146

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Pharmacy and Pharmaceutical Sciences

Discipline

Pharmaceutical Sciences

Top Specialties

Antibody | Cancer | Magnetic Resonance Imaging

Metrics Summary

Publication Count

Predicted Citations

1,173

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

Add Delete
Effect of molecular size on interstitial pharmacokinetics and tissue catabolism of antibodies (journal article) Rafidi, Hanine \| Rajan, Sharmila \| Urban, Konnie \| Shatz-Binder, Whitney \| Hui, Keliana \| Ferl, Gregory Z. \| Kamath, Amrita V. \| Boswell, C. Andrew mAbs, volume 14, issue 1 (2022). 10.1080/19420862.2022.2085535 Cited by (7) \| Cite \| Source
Automated segmentation of lungs and lung tumors in mouse micro-CT scans (journal article) Ferl, Gregory Z. \| Barck, Kai H. \| Patil, Jasmine \| Jemaa, Skander \| Malamut, Evelyn J. \| Lima, Anthony \| Long, Jason E. \| Cheng, Jason H. \| Junttila, Melissa R. \| Carano, Richard A.D. iScience, volume 25, issue 12, pages 105712- (2022). 10.1016/j.isci.2022.105712 Cited by (8) \| Cite \| Source
Imaging Reveals Importance of Shape and Flexibility for Glomerular Filtration of Biologics (journal article) Rafidi, Hanine \| Estevez, Alberto \| Ferl, Gregory Z. \| Mandikian, Danielle \| Stainton, Shannon \| Sermeño, Lauren \| Williams, Simon P. \| Kamath, Amrita V. \| Koerber, James T. \| Boswell, C. Andrew Molecular Cancer Therapeutics, volume 20, issue 10, pages 2008-2015 (2021). 10.1158/1535-7163.MCT-21-0116 Cited by (8) \| Cite \| Source
Valency of HER2 Targeting Antibodies Influences Tumor Cell Internalization and Penetration (journal article) Ramos, Madeleine K. \| Mandikian, Danielle \| Sermeño, Lauren N. \| King, Anna \| Dent, Alecia T. \| Ho, Jason \| Ulufatu, Sheila \| Lombana, T. Noelle \| Spiess, Christoph \| Go, Mary Ann T. \| ... \| Boswell, C. Andrew Molecular Cancer Therapeutics, volume 20, issue 10, pages 1956-1965 (2021). 10.1158/1535-7163.MCT-20-1097 Cited by (2) \| Cite \| Source
Mechanistic Modeling of Soluble Aβ Dynamics and Target Engagement in the Brain by Anti-Aβ mAbs in Alzheimer’s Disease (journal article) Ferl, Gregory Z. \| Fuji, Reina N. \| Atwal, Jasvinder K. \| Sun, Tony \| Ramanujan, Saroja \| Quartino, Angelica L. Current Alzheimer Research, volume 17, issue 4, pages 393-406 (2020). 10.2174/1567205017666200302122307 Cited by (7) \| Cite \| Source
Effect of Modulating FcRn Binding on Direct and Pretargeted Tumor Uptake of Full-length Antibodies (journal article) Nazarova, Lidia \| Rafidi, Hanine \| Mandikian, Danielle \| Ferl, Gregory Z. \| Koerber, James T. \| Davies, Christopher W. \| Ulufatu, Sheila \| Ho, Jason \| Lau, Jeffrey \| Yu, Shang-Fan \| ... \| Boswell, C. Andrew Molecular Cancer Therapeutics, volume 19, issue 4, pages 1052-1058 (2020). 10.1158/1535-7163.MCT-19-1015 Cited by (6) \| Cite \| Source
Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer (journal article) Boswell, C. Andrew \| Yadav, Daniela Bumbaca \| Mundo, Eduardo E. \| Yu, Shang-Fan \| Lacap, Jennifer Arca \| Fourie-O’Donohue, Aimee \| Kozak, Katherine R. \| Ferl, Gregory Z. \| Zhang, Crystal \| Ho, Jason \| ... \| Lin, Kedan Oncotarget, volume 10, issue 58, pages 6234-6244 (2019). 10.18632/oncotarget.27263 Cited by (13) \| Cite \| Source
VCAM-1 Density and Tumor Perfusion Predict T-cell Infiltration and Treatment Response in Preclinical Models (journal article) Riegler, Johannes \| Gill, Herman \| Ogasawara, Annie \| Hedehus, Maj \| Javinal, Vincent \| Oeh, Jason \| Ferl, Gregory Z. \| Marik, Jan \| Williams, Simon \| Sampath, Deepak \| ... \| Carano, Richard A.D. Neoplasia, volume 21, issue 10, pages 1036-1050 (2019). 10.1016/j.neo.2019.08.003 Cited by (15) \| Cite \| Source
Site-specific conjugation allows modulation of click reaction stoichiometry for pretargeted SPECT imaging (journal article) Mandikian, Danielle \| Rafidi, Hanine \| Adhikari, Pragya \| Venkatraman, Priya \| Nazarova, Lidia \| Fung, Gabriel \| Figueroa, Isabel \| Ferl, Gregory Z. \| Ulufatu, Sheila \| Ho, Jason \| ... \| Boswell, C. Andrew mAbs, volume 10, issue 8, pages 1269-1280 (2018). 10.1080/19420862.2018.1521132 Cited by (8) \| Cite \| Source
Tissue Physiology of Cynomolgus Monkeys: Cross-Species Comparison and Implications for Translational Pharmacology (journal article) Mandikian, Danielle \| Figueroa, Isabel \| Oldendorp, Amy \| Rafidi, Hanine \| Ulufatu, Sheila \| Schweiger, Michelle G. \| Couch, Jessica A. \| Dybdal, Noel \| Joseph, Sean B. \| Prabhu, Saileta \| ... \| Boswell, C. Andrew The AAPS Journal, volume 20, issue 6 (2018). 10.1208/s12248-018-0264-z Cited by (19) \| Cite \| Source
A Preclinical Population Pharmacokinetic Model for Anti‐CD20/CD3 T‐Cell‐Dependent Bispecific Antibodies (journal article) Ferl, Gregory Z. \| Reyes, Arthur \| Sun, Liping L. \| Cheu, Melissa \| Oldendorp, Amy \| Ramanujan, Saroja \| Stefanich, Eric G. Clinical and Translational Science, volume 11, issue 3, pages 296-304 (2018). 10.1111/cts.12535 Cited by (22) \| Cite \| Source \| Open Access
[P1–109]: MATHEMATICAL MODEL OF AMYLOID BETA (Aβ) DYNAMICS TO ASSESS TARGET ENGAGEMENT OF SOLUBLE Aβ OLIGOMERS BY CRENEZUMAB IN THE ALZHEIMER's DISEASE BRAIN (journal article) Ferl, Gregory Z. \| Fuji, Reina N. \| Atwal, Jasvinder \| Ramanujan, Saroja \| Quartino, Angelica Alzheimer's & Dementia, volume 13, issue 7S_Part_5 (2017). 10.1016/j.jalz.2017.06.176 Cite \| Source
Physiologically based pharmacokinetic models of small molecules and therapeutic antibodies: a mini‐review on fundamental concepts and applications (journal article) Ferl, Gregory Z. \| Theil, Frank‐Peter \| Wong, Harvey Biopharmaceutics & Drug Disposition, volume 37, issue 2, pages 75-92 (2016). 10.1002/bdd.1994 Cited by (38) \| Cite \| Source
GPU-Accelerated Compartmental Modeling Analysis of DCE-MRI Data from Glioblastoma Patients Treated with Bevacizumab (journal article) Hsu, Yu-Han H. \| Huang, Ziyin \| Ferl, Gregory Z. \| Ng, Chee M. PLOS ONE, volume 10, issue 3, pages e0118421- (2015). 10.1371/journal.pone.0118421 Cited by (4) \| Cite \| Source \| Open Access
Mixed‐effects modeling of clinical DCE‐MRI data: Application to colorectal liver metastases treated with bevacizumab (journal article) Ferl, Gregory Z. \| O'Connor, James P.B. \| Parker, Geoffrey J.M. \| Carano, Richard A.D. \| Acharya, Shiv J. \| Jayson, Gordon C. \| Port, Ruediger E. Journal of Magnetic Resonance Imaging, volume 41, issue 1, pages 132-141 (2015). 10.1002/jmri.24514 Cited by (8) \| Cite \| Source
GPU-accelerated nonparametric kinetic analysis of DCE-MRI data from glioblastoma patients treated with bevacizumab (journal article) Hsu, Yu-Han H. \| Ferl, Gregory Z. \| Ng, Chee M. Magnetic Resonance Imaging, volume 31, issue 4, pages 618-623 (2013). 10.1016/j.mri.2012.09.007 Cited by (7) \| Cite \| Source
Quantification of Antiangiogenic and Antivascular Drug Activity by Kinetic Analysis of DCE-MRI Data (journal article) Ferl, G Z \| Port, R E Clinical Pharmacology & Therapeutics, volume 92, issue 1, pages 118-124 (2012). 10.1038/clpt.2012.63 Cited by (14) \| Cite \| Source
Erratum to: A Predictive Model of Therapeutic Monoclonal Antibody Dynamics and Regulation by the Neonatal Fc Receptor (FcRn) (journal article) Ferl, Gregory Z. \| Wu, Anna M. \| DiStefano, Joseph J. Annals of Biomedical Engineering, volume 39, issue 10 (2011). 10.1007/s10439-011-0373-7 Cited by (77) \| Cite \| Source \| Open Access
Effects of Anti-VEGF on Predicted Antibody Biodistribution: Roles of Vascular Volume, Interstitial Volume, and Blood Flow (journal article) Boswell, C. Andrew \| Ferl, Gregory Z. \| Mundo, Eduardo E. \| Bumbaca, Daniela \| Schweiger, Michelle G. \| Theil, Frank-Peter \| Fielder, Paul J. \| Khawli, Leslie A. PLoS ONE, volume 6, issue 3, pages e17874- (2011). 10.1371/journal.pone.0017874 Cited by (29) \| Cite \| Source \| Open Access
: An R Package for Deconvolution Analysis and Visualization of DCE-MRI Data (journal article) Ferl, Gregory Z. Journal of Statistical Software, volume 44, issue 3 (2011). 10.18637/jss.v044.i03 Cited by (10) \| Cite \| Source \| Open Access