Lake-Ee Quek

ScholarGPS® ID: 24131450080312

Affiliation

University of Sydney, Sydney, Australia

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Statistics

Top Specialties

Metabolism | Glucose | Insulin | Biotechnology | Cancer

Metrics Summary

Publication Count

Predicted Citations

3,528

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Peroxisomal β-oxidation enzyme, DECR2, regulates lipid metabolism and promotes treatment resistance in advanced prostate cancer (journal article) Mah, Chui Yan \| Nguyen, An Dieu Trang \| Niijima, Takuto \| Helm, Madison \| Dehairs, Jonas \| Ryan, Feargal J. \| Ryan, Natalie \| Quek, Lake-Ee \| Hoy, Andrew J. \| Don, Anthony S. \| ... \| Butler, Lisa M. British Journal of Cancer, volume 130, issue 5, pages 741-754 (2024). 10.1038/s41416-023-02557-8 Cite \| Source
Fatty acid elongation regulates mitochondrial β-oxidation and cell viability in prostate cancer by controlling malonyl-CoA levels (journal article) Scott, Julia S. \| Quek, Lake-Ee \| Hoy, Andrew J. \| Swinnen, Johannes V. \| Nassar, Zeyad D. \| Butler, Lisa M. Biochemical and Biophysical Research Communications, volume 691 (2024). 10.1016/j.bbrc.2023.149273 Cite \| Source
Host–microbiome interactions in nicotinamide mononucleotide (NMN) deamidation (journal article) Kim, Lynn‐Jee \| Chalmers, Timothy J. \| Madawala, Romanthi \| Smith, Greg C. \| Li, Catherine \| Das, Abhirup \| Poon, Eric Wing Keung \| Wang, Jun \| Tucker, Simon P. \| Sinclair, David A. \| ... \| Wu, Lindsay E. FEBS Letters, volume 597, issue 17, pages 2196-2220 (2023). 10.1002/1873-3468.14698 Cited by (5) \| Cite \| Source
β3 adrenergic agonism: A novel pathway which improves right ventricular‐pulmonary arterial hemodynamics in pulmonary arterial hypertension (journal article) Karimi Galougahi, Keyvan \| Zhang, Yunjia \| Kienzle, Vivian \| Liu, Chia‐Chi \| Quek, Lake‐Ee \| Patel, Sanjay \| Lau, Edmund \| Cordina, Rachael L. \| Figtree, Gemma A. \| Celermajer, David S. Physiological Reports, volume 11, issue 1 (2023). 10.14814/phy2.15549 Cite \| Source
Insulin sensitivity is preserved in mice made obese by feeding a high starch diet (journal article) Brandon, Amanda E \| Small, Lewin \| Nguyen, Tuong-Vi \| Suryana, Eurwin \| Gong, Henry \| Yassmin, Christian \| Hancock, Sarah E \| Pulpitel, Tamara \| Stonehouse, Sophie \| Prescott, Letisha \| ... \| Cooney, Gregory J eLife, volume 11 (2022). 10.7554/eLife.79250 Cited by (5) \| Cite \| Source
Glutamine addiction promotes glucose oxidation in triple-negative breast cancer (journal article) Quek, Lake-Ee \| van Geldermalsen, Michelle \| Guan, Yi Fang \| Wahi, Kanu \| Mayoh, Chelsea \| Balaban, Seher \| Pang, Angel \| Wang, Qian \| Cowley, Mark J. \| Brown, Kristin K. \| ... \| Holst, Jeff Oncogene, volume 41, issue 34, pages 4066-4078 (2022). 10.1038/s41388-022-02408-5 Cited by (17) \| Cite \| Source
The topology of genome-scale metabolic reconstructions unravels independent modules and high network flexibility (journal article) Martínez, Verónica S. \| Saa, Pedro A. \| Jooste, Jason \| Tiwari, Kanupriya \| Quek, Lake-Ee \| Nielsen, Lars K. PLOS Computational Biology, volume 18, issue 6, pages e1010203- (2022). 10.1371/journal.pcbi.1010203 Cited by (5) \| Cite \| Source
Exercise-induced benefits on glucose handling in a model of diet-induced obesity are reduced by concurrent nicotinamide mononucleotide (journal article) Yu, Josephine \| Laybutt, David Ross \| Kim, Lynn-Jee \| Quek, Lake-Ee \| Wu, Lindsay E. \| Morris, Margaret J. \| Youngson, Neil A. American Journal of Physiology-Endocrinology and Metabolism, volume 321, issue 1, pages E176-E189 (2021). 10.1152/ajpendo.00446.2020 Cited by (15) \| Cite \| Source
Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin (journal article) Quek, Lake-Ee \| Krycer, James R. \| Ohno, Satoshi \| Yugi, Katsuyuki \| Fazakerley, Daniel J. \| Scalzo, Richard \| Elkington, Sarah D. \| Dai, Ziwei \| Hirayama, Akiyoshi \| Ikeda, Satsuki \| ... \| Kuroda, Shinya iScience, volume 23, issue 12, pages 101786- (2020). 10.1016/j.isci.2020.101786 Cited by (3) \| Cite \| Source
Kinetic Trans-omic Analysis Reveals Key Regulatory Mechanisms for Insulin-Regulated Glucose Metabolism in Adipocytes (journal article) Ohno, Satoshi \| Quek, Lake-Ee \| Krycer, James R. \| Yugi, Katsuyuki \| Hirayama, Akiyoshi \| Ikeda, Satsuki \| Shoji, Futaba \| Suzuki, Kumi \| Soga, Tomoyoshi \| James, David E. \| Kuroda, Shinya iScience, volume 23, issue 9, pages 101479- (2020). 10.1016/j.isci.2020.101479 Cited by (16) \| Cite \| Source
Insulin signaling requires glucose to promote lipid anabolism in adipocytes (journal article) Krycer, James R. \| Quek, Lake-Ee \| Francis, Deanne \| Zadoorian, Armella \| Weiss, Fiona C. \| Cooke, Kristen C. \| Nelson, Marin E. \| Diaz-Vegas, Alexis \| Humphrey, Sean J. \| Scalzo, Richard \| ... \| James, David E. Journal of Biological Chemistry, volume 295, issue 38, pages 13250-13266 (2020). 10.1074/jbc.RA120.014907 Cited by (36) \| Cite \| Source
Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin (journal article) Quek, Lake-Ee \| Krycer, James R. \| Ohno, Satoshi \| Yugi, Katsuyuki \| Fazakerley, Daniel J. \| Scalzo, Richard \| Elkington, Sarah D. \| Dai, Ziwei \| Hirayama, Akiyoshi \| Ikeda, Satsuki \| ... \| Kuroda, Shinya iScience, volume 23, issue 2, pages 100855- (2020). 10.1016/j.isci.2020.100855 Cited by (22) \| Cite \| Source
Lactate production is a prioritized feature of adipocyte metabolism (journal article) Krycer, James R. \| Quek, Lake-Ee \| Francis, Deanne \| Fazakerley, Daniel J. \| Elkington, Sarah D. \| Diaz-Vegas, Alexis \| Cooke, Kristen C. \| Weiss, Fiona C. \| Duan, Xiaowen \| Kurdyukov, Sergey \| ... \| James, David E. Journal of Biological Chemistry, volume 295, issue 1, pages 83-98 (2020). 10.1074/jbc.RA119.011178 Cited by (44) \| Cite \| Source
Metabolites downstream of predicted loss-of-function variants inform relationship to disease (journal article) Li, Mengbo \| Wang, Andy \| Quek, Lake-Ee \| Vernon, Stephen \| Figtree, Gemma A. \| Yang, Jean \| O'Sullivan, John F. Molecular Genetics and Metabolism, volume 128, issue 4, pages 476-482 (2019). 10.1016/j.ymgme.2019.10.002 Cite \| Source
Snail-Overexpression Induces Epithelial-mesenchymal Transition and Metabolic Reprogramming in Human Pancreatic Ductal Adenocarcinoma and Non-tumorigenic Ductal Cells (journal article) Liu, Menghan \| Hancock, Sarah E. \| Sultani, Ghazal \| Wilkins, Brendan P. \| Ding, Eileen \| Osborne, Brenna \| Quek, Lake-Ee \| Turner, Nigel Journal of Clinical Medicine, volume 8, issue 6, pages 822- (2019). 10.3390/jcm8060822 Cited by (27) \| Cite \| Source
Using the Human Genome-Scale Metabolic Model Recon 2 for Steady-State Flux Analysis of Cancer Cell Metabolism (book chapter) In Cancer Metabolism Quek, Lake-Ee \| Turner, Nigel Springer New York (2019) 10.1007/978-1-4939-9027-6_25 Cited by (3) \| Cite \| Source
Symposium12-4 (journal article) Krycer, James R. \| Fazakerley, Daniel J. \| Quek, Lake-Ee \| Scalzo, Richard \| Hodson, Mark P. \| Domanova, Westa \| Parker, Benjamin L. \| Nelson, Marin E. \| Humphrey, Sean J. \| Turner, Nigel \| ... \| James, David E. Japanese Journal of Physical Fitness and Sports Medicine, volume 68, issue 1, pages 55-55 (2019). 10.7600/jspfsm.68.55_2 Cite \| Source
Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways (journal article) van Geldermalsen, Michelle \| Quek, Lake-Ee \| Turner, Nigel \| Freidman, Natasha \| Pang, Angel \| Guan, Yi Fang \| Krycer, James R. \| Ryan, Renae \| Wang, Qian \| Holst, Jeff BMC Cancer, volume 18, issue 1 (2018). 10.1186/s12885-018-4599-8 Cited by (46) \| Cite \| Source \| Open Access
Protein hypoacylation induced by Sirt5 overexpression has minimal metabolic effect in mice (journal article) Bentley, Nicholas L. \| Fiveash, Corrine E. \| Osborne, Brenna \| Quek, Lake-Ee \| Ogura, Masahito \| Inagaki, Nobuya \| Cooney, Gregory J. \| Polly, Patsie \| Montgomery, Magdalene K. \| Turner, Nigel Biochemical and Biophysical Research Communications, volume 503, issue 3, pages 1349-1355 (2018). 10.1016/j.bbrc.2018.07.047 Cited by (7) \| Cite \| Source
From reconstruction to C4 metabolic engineering: A case study for overproduction of polyhydroxybutyrate in bioenergy grasses (journal article) Gomes de Oliveira Dal’Molin, Cristiana \| Quek, Lake-Ee \| Saa, Pedro A. \| Palfreyman, Robin \| Nielsen, Lars Keld Plant Science, volume 273 (2018). 10.1016/j.plantsci.2018.03.027 Cited by (7) \| Cite \| Source