Brent S. McKenzie

ScholarGPS® ID: 22601811089552

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Medicine

Discipline

Immunology

Top Specialties

Inflammation | Cancer | Arthritis | Antibody | Granulocyte-macrophage Colony-stimulating Factor

Metrics Summary

Publication Count

Predicted Citations

8,133

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Genetic inactivation of RIP1 kinase activity in rats protects against ischemic brain injury (journal article) Stark, Kimberly \| Goncharov, Tatiana \| Varfolomeev, Eugene \| Xie, Luke \| Ngu, Hai \| Peng, Ivan \| Anderson, Keith R. \| Verschueren, Erik \| Choi, Meena \| Kirkpatrick, Donald S. \| ... \| Bingol, Baris Cell Death & Disease, volume 12, issue 4 (2021). 10.1038/s41419-021-03651-6 Cited by (9) \| Cite \| Source
CD96 functions as a co‐stimulatory receptor to enhance CD8+ T cell activation and effector responses (journal article) Chiang, Eugene Y. \| de Almeida, Patricia E. \| de Almeida Nagata, Denise E. \| Bowles, Kristin Harden \| Du, Xiangnan \| Chitre, Avantika S. \| Banta, Karl L. \| Kwon, Youngsu \| McKenzie, Brent \| Mittman, Stephanie \| ... \| Grogan, Jane L. European Journal of Immunology, volume 50, issue 6, pages 891-902 (2020). 10.1002/eji.201948405 Cited by (59) \| Cite \| Source
RIP1 kinase activity is critical for skin inflammation but not for viral propagation (journal article) Webster, Joshua D. \| Kwon, Youngsu C. \| Park, Summer \| Zhang, Hua \| Corr, Nick \| Ljumanovic, Nina \| Adedeji, Adeyemi O. \| Varfolomeev, Eugene \| Goncharov, Tatiana \| Preston, Jessica \| ... \| Vucic, Domagoj Journal of Leukocyte Biology, volume 107, issue 6, pages 941-952 (2020). 10.1002/JLB.3MA1219-398R Cited by (33) \| Cite \| Source
Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins (journal article) Lim, Junghyun \| Park, Hyunjoo \| Heisler, Jason \| Maculins, Timurs \| Roose-Girma, Merone \| Xu, Min \| Mckenzie, Brent \| van Lookeren Campagne, Menno \| Newton, Kim \| Murthy, Aditya eLife, volume 8 (2019). 10.7554/eLife.44452 Cited by (80) \| Cite \| Source
Micro-CT imaging and structural analysis of glomeruli in a model of Adriamycin-induced nephropathy (journal article) Xie, Luke \| Koukos, Georgios \| Barck, Kai \| Foreman, Oded \| Lee, Wyne P. \| Brendza, Robert \| Eastham-Anderson, Jeff \| McKenzie, Brent S. \| Peterson, Andrew \| Carano, Richard A. D. American Journal of Physiology-Renal Physiology, volume 316, issue 1, pages F76-F89 (2019). 10.1152/ajprenal.00331.2018 Cited by (21) \| Cite \| Source
Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy (journal article) Katschke, Kenneth J. \| Xi, Hongkang \| Cox, Christian \| Truong, Tom \| Malato, Yann \| Lee, Wyne P. \| McKenzie, Brent \| Arceo, Rommel \| Tao, Jianhua \| Rangell, Linda \| ... \| van Lookeren Campagne, Menno Scientific Reports, volume 8, issue 1 (2018). 10.1038/s41598-018-25557-8 Cited by (45) \| Cite \| Source \| Open Access
Factor XII inhibitors for the treatment of neurological inflammatory disorders (patent) Meuth, Sven \| Goebel, Kerstin \| Kleinschnitz, Christoph \| McKenzie, Brent \| Nolte, Marc Patent Number: 9957329 (2018) Cite \| Source
Inflammatory Bowel Disease Susceptibility Gene C1ORF106 Regulates Intestinal Epithelial Permeability (journal article) Manzanillo, Paolo \| Mouchess, Maria \| Ota, Naruhisa \| Dai, Bingbing \| Ichikawa, Ryan \| Wuster, Arthur \| Haley, Benjamin \| Alvarado, Gabriela \| Kwon, Youngsu \| Caothien, Roger \| ... \| Yi, Tangsheng ImmunoHorizons, volume 2, issue 5, pages 164-171 (2018). 10.4049/immunohorizons.1800027 Cited by (7) \| Cite \| Source \| Open Access
Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling (journal article) Samie, Mohammad \| Lim, Junghyun \| Verschueren, Erik \| Baughman, Joshua M. \| Peng, Ivan \| Wong, Aaron \| Kwon, Youngsu \| Senbabaoglu, Yasin \| Hackney, Jason A. \| Keir, Mary \| ... \| Murthy, Aditya Nature Immunology, volume 19, issue 3, pages 246-254 (2018). 10.1038/s41590-017-0042-6 Cited by (95) \| Cite \| Source
TPL2 kinase action and control of inflammation (journal article) Xu, Daqi \| Matsumoto, Marissa L. \| McKenzie, Brent S. \| Zarrin, Ali A. Pharmacological Research, volume 129 (2018). 10.1016/j.phrs.2017.11.031 Cited by (51) \| Cite \| Source \| Open Access
Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins (journal article) Whiteley, Alexandra M \| Prado, Miguel A \| Peng, Ivan \| Abbas, Alexander R \| Haley, Benjamin \| Paulo, Joao A \| Reichelt, Mike \| Katakam, Anand \| Sagolla, Meredith \| Modrusan, Zora \| ... \| Brown, Eric J eLife, volume 6 (2017). 10.7554/eLife.26435 Cited by (31) \| Cite \| Source \| Open Access
Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis (journal article) Campbell, Ian K. \| Leong, David \| Edwards, Kirsten M. \| Rayzman, Veronika \| Ng, Milica \| Goldberg, Gabrielle L. \| Wilson, Nicholas J. \| Scalzo-Inguanti, Karen \| Mackenzie-Kludas, Charley \| Lawlor, Kate E. \| ... \| Andrews, Arna E. The Journal of Immunology, volume 197, issue 11, pages 4392-4402 (2016). 10.4049/jimmunol.1600121 Cited by (63) \| Cite \| Source
GM-CSF primes cardiac inflammation in a mouse model of Kawasaki disease (journal article) Stock, Angus T. \| Hansen, Jacinta A. \| Sleeman, Matthew A. \| McKenzie, Brent S. \| Wicks, Ian P. Journal of Experimental Medicine, volume 213, issue 10, pages 1983-1998 (2016). 10.1084/jem.20151853 Cited by (71) \| Cite \| Source \| Open Access
Treatment of neurological conditions (patent) McKenzie, Brent Steven \| Curwen, Peter Frederick \| Maraskovsky, Eugene Patent Number: 9364534 (2016) Cite \| Source
Treatment of neurological conditions (patent) McKenzie, Brent Steven \| Curwen, Peter Frederick \| Maraskovsky, Eugene Patent Number: 9352038 (2016) Cite \| Source
ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation (journal article) Pearson, Claire \| Thornton, Emily E \| McKenzie, Brent \| Schaupp, Anna-Lena \| Huskens, Nicky \| Griseri, Thibault \| West, Nathaniel \| Tung, Sim \| Seddon, Benedict P \| Uhlig, Holm H \| Powrie, Fiona eLife, volume 5 (2016). 10.7554/eLife.10066 Cited by (179) \| Cite \| Source \| Open Access
G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis (journal article) Goldberg, Gabrielle L. \| Cornish, Ann L. \| Murphy, Jane \| Pang, Ee Shan \| Lim, Lyndell L. \| Campbell, Ian K. \| Scalzo-Inguanti, Karen \| Chen, Xiangting \| McMenamin, Paul G. \| Maraskovsky, Eugene \| ... \| Wicks, Ian P. The American Journal of Pathology, volume 186, issue 1, pages 172-184 (2016). 10.1016/j.ajpath.2015.09.008 Cited by (20) \| Cite \| Source
Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis (journal article) Griseri, Thibault \| Arnold, Isabelle C. \| Pearson, Claire \| Krausgruber, Thomas \| Schiering, Chris \| Franchini, Fanny \| Schulthess, Julie \| McKenzie, Brent S. \| Crocker, Paul R. \| Powrie, Fiona Immunity, volume 43, issue 1, pages 187-199 (2015). 10.1016/j.immuni.2015.07.008 Cited by (143) \| Cite \| Source \| Open Access
Coagulation factor XII mediates fibrotic response to lung injury (journal article) Wygrecka, M \| Jablonska, E \| Henneke, I \| Renne, T \| Panousis, K \| McKenzie, B \| Kosanovic, D \| Kwapiszewska, G \| Nolte, MW \| Schermuly, RT \| ... \| Markart, P Pneumologie, volume 69, issue 05 (2015). 10.1055/s-0035-1551907 Cited by (2) \| Cite \| Source
Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils (journal article) Campbell, Ian K. \| Miescher, Sylvia \| Branch, Donald R. \| Mott, Patrick J. \| Lazarus, Alan H. \| Han, Dongji \| Maraskovsky, Eugene \| Zuercher, Adrian W. \| Neschadim, Anton \| Leontyev, Danila \| ... \| Käsermann, Fabian The Journal of Immunology, volume 192, issue 11, pages 5031-5038 (2014). 10.4049/jimmunol.1301611 Cited by (115) \| Cite \| Source \| Open Access