Bin Zhu

ScholarGPS® ID: 22540900050662

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Medicinal Chemistry | Antibacterial Activity

Metrics Summary

Publication Count

Predicted Citations

219

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Discovery and Optimization of 7-Alkylidenyltetrahydroindazole-Based Acylsulfonamide EP3 Antagonists (journal article) Zhu, Bin \| Zhang, Xuqing \| Guo, Lili \| Rankin, Matthew \| Bakaj, Ivona \| Ho, George \| Lee, Seunghun P. \| Norquay, Lisa \| Macielag, Mark ACS Medicinal Chemistry Letters, volume 13, issue 1, pages 111-117 (2022). 10.1021/acsmedchemlett.1c00594 Cited by (1) \| Cite \| Source
Optimization of physicochemical properties of pyridone-based EP3 receptor antagonists (journal article) Zhang, Xuqing \| Zhu, Bin \| Guo, Lili \| Bakaj, Ivona \| Rankin, Matthew \| Ho, George \| Kauffman, Jack \| Lee, Seunghun P. \| Norquay, Lisa \| Macielag, Mark Bioorganic & Medicinal Chemistry Letters, volume 47 (2021). 10.1016/j.bmcl.2021.128172 Cited by (3) \| Cite \| Source
Erratum to “Optimization of physicochemical properties of pyridone-based EP3 receptor antagonists” [Bioorg. Med. Chem. Lett. 47 (2021) 128172] (journal article) Zhang, Xuqing \| Zhu, Bin \| Guo, Lili \| Bakaj, Ivona \| Rankin, Matthew \| Ho, George \| Kauffman, Jack \| Lee, Seunghun P. \| Norquay, Lisa \| Macielag, Mark Bioorganic & Medicinal Chemistry Letters, volume 47 (2021). 10.1016/j.bmcl.2021.128232 Cite \| Source
Discovery of a novel series of guanidinebenzoates as gut-restricted enteropeptidase and trypsin dual inhibitors for the treatment of metabolic syndrome (journal article) Zhang, Xuqing \| Zhu, Bin \| Sun, Weimei \| Wang, Mina \| Albarazanji, Kamal \| Ghosh, Brahma \| Cummings, Maxwell \| Lenhard, James \| Leonard, James \| Macielag, Mark \| Lanter, James Bioorganic & Medicinal Chemistry Letters, volume 40 (2021). 10.1016/j.bmcl.2021.127939 Cited by (2) \| Cite \| Source
Discovery of a Novel Series of Pyridone-Based EP3 Antagonists for the Treatment of Type 2 Diabetes (journal article) Zhang, Xuqing \| Zhu, Bin \| Guo, Lili \| Bakaj, Ivona \| Rankin, Matthew \| Ho, George \| Kauffman, Jack \| Lee, Seunghun P. \| Norquay, Lisa \| Macielag, Mark J. ACS Medicinal Chemistry Letters, volume 12, issue 3, pages 451-458 (2021). 10.1021/acsmedchemlett.0c00667 Cited by (3) \| Cite \| Source
Targeting Enteropeptidase with Reversible Covalent Inhibitors To Achieve Metabolic Benefits (journal article) Sun, Weimei \| Zhang, Xuqing \| Cummings, Maxwell D. \| Albarazanji, Kamal \| Wu, Jiejun \| Wang, Mina \| Alexander, Richard \| Zhu, Bin \| Zhang, YueMei \| Leonard, James \| ... \| Lenhard, James Journal of Pharmacology and Experimental Therapeutics, volume 375, issue 3, pages 510-521 (2020). 10.1124/jpet.120.000219 Cited by (14) \| Cite \| Source
The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors (journal article) Zhu, Bin \| Connolly, Peter J. \| Zhang, Yue-Mei \| McDonnell, Mark E. \| Bian, Haiyan \| Lin, Shu-Chen \| Liu, Li \| Zhang, Sui-Po \| Chevalier, Kristen M. \| Brandt, Michael R. \| ... \| Macielag, Mark J. Bioorganic & Medicinal Chemistry Letters, volume 30, issue 14, pages 127243- (2020). 10.1016/j.bmcl.2020.127243 Cited by (12) \| Cite \| Source
The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL) (journal article) Zhu, Bin \| Connolly, Peter J. \| Zhang, Sui-Po \| Chevalier, Kristen M. \| Milligan, Cynthia M. \| Flores, Christopher M. \| Macielag, Mark J. Bioorganic & Medicinal Chemistry Letters, volume 30, issue 12, pages 127198- (2020). 10.1016/j.bmcl.2020.127198 Cited by (7) \| Cite \| Source
Tetrahydropyrazolo[4,3- c ]pyridine derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists (journal article) Zhu, Bin \| Matthews, Jay M. \| Xia, Mingde \| Black, Shawn \| Chen, Cailin \| Hou, Cuifen \| Liang, Yin \| Tang, Yuting \| Macielag, Mark J. Bioorganic & Medicinal Chemistry Letters, volume 26, issue 22, pages 5597-5601 (2016). 10.1016/j.bmcl.2016.09.026 Cited by (5) \| Cite \| Source
Tetrahydroindazole derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists (journal article) Matthews, Jay M. \| McNally, James J. \| Connolly, Peter J. \| Xia, Mingde \| Zhu, Bin \| Black, Shawn \| Chen, Cailin \| Hou, Cuifen \| Liang, Yin \| Tang, Yuting \| Macielag, Mark J. Bioorganic & Medicinal Chemistry Letters, volume 26, issue 21, pages 5346-5349 (2016). 10.1016/j.bmcl.2016.09.025 Cited by (18) \| Cite \| Source
Adenosine monophosphate-activated protein kinase activation mediates the leptin-induced attenuation of cognitive impairment in a streptozotocin-induced rat model (journal article) ZHU, BIN \| Jiang, RI-YUE \| Yang, Chun \| LIU, Ning Experimental and Therapeutic Medicine, volume 9, issue 5, pages 1998-2002 (2015). 10.3892/etm.2015.2317 Cited by (2) \| Cite \| Source \| Open Access
Arylglycine derivatives as potent transient receptor potential melastatin 8 (TRPM8) antagonists (journal article) Zhu, Bin \| Xia, Mingde \| Xu, Xiaoqing \| Ludovici, Donald W. \| Tennakoon, Manomi \| Youngman, Mark A. \| Matthews, Jay M. \| Dax, Scott L. \| Colburn, Raymond W. \| Qin, Ning \| ... \| Macielag, Mark J. Bioorganic & Medicinal Chemistry Letters, volume 23, issue 7, pages 2234-2237 (2013). 10.1016/j.bmcl.2013.01.062 Cited by (24) \| Cite \| Source
Synthesis and antibacterial activity of 7-(1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-7-yl) quinolones (journal article) Zhu, Bin \| Marinelli, Brett A. \| Goldschmidt, Raul \| Foleno, Barbara D. \| Hilliard, Jamese J. \| Bush, Karen \| Macielag, Mark J. Bioorganic & Medicinal Chemistry Letters, volume 19, issue 17, pages 4933-4936 (2009). 10.1016/j.bmcl.2009.07.087 Cited by (21) \| Cite \| Source
Synthesis and antibacterial activity of 3-keto-6-O-carbamoyl-11,12-cyclic thiocarbamate erythromycin A derivatives (journal article) Zhu, Bin \| Marinelli, Brett A. \| Abbanat, Darren \| Foleno, Barbara D. \| Bush, Karen \| Macielag, Mark J. Bioorganic & Medicinal Chemistry Letters, volume 17, issue 14, pages 3900-3904 (2007). 10.1016/j.bmcl.2007.04.104 Cited by (28) \| Cite \| Source
Synthesis and antibacterial activity of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives (journal article) Zhu, Bin \| Marinelli, Brett A. \| Abbanat, Darren \| Foleno, Barbara D. \| Henninger, Todd C. \| Bush, Karen \| Macielag, Mark J. Bioorganic & Medicinal Chemistry Letters, volume 16, issue 4, pages 1054-1059 (2006). 10.1016/j.bmcl.2005.10.074 Cited by (13) \| Cite \| Source
Novel erythromycin A derivatives: synthesis of 11,12-benzoxazine ketolides (journal article) Zhu, Bin \| Maden, Amy \| Macielag, Mark J. Tetrahedron Letters, volume 46, issue 11, pages 1783-1785 (2005). 10.1016/j.tetlet.2005.01.126 Cited by (1) \| Cite \| Source