Amy Sambrone

ScholarGPS® ID: 21884778374806

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Pharmacy and Pharmaceutical Sciences

Discipline

Pharmaceutical Sciences

Top Specialties

Medicinal Chemistry

Metrics Summary

Publication Count

Predicted Citations

898

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha (journal article) Zhang, Birong \| Kiefer, James R. \| Blake, Robert A. \| Chang, Jae H. \| Hartman, Steven \| Ingalla, Ellen Rei \| Kleinheinz, Tracy \| Mody, Vidhi \| Nannini, Michelle \| Ortwine, Daniel F. \| ... \| Liang, Jun Bioorganic & Medicinal Chemistry Letters, volume 29, issue 7, pages 905-911 (2019). 10.1016/j.bmcl.2019.01.036 Cited by (11) \| Cite \| Source
Tankyrase Inhibition Causes Reversible Intestinal Toxicity in Mice with a Therapeutic Index < 1 (journal article) Zhong, Yu \| Katavolos, Paula \| Nguyen, Trung \| Lau, Ted \| Boggs, Jason \| Sambrone, Amy \| Kan, David \| Merchant, Mark \| Harstad, Eric \| Diaz, Dolores \| ... \| Schutten, Melissa Toxicologic Pathology, volume 44, issue 2, pages 267-278 (2016). 10.1177/0192623315621192 Cited by (72) \| Cite \| Source \| Open Access
Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis (journal article) Ndubaku, Chudi O. \| Crawford, Terry D. \| Chen, Huifen \| Boggs, Jason W. \| Drobnick, Joy \| Harris, Seth F. \| Jesudason, Rajiv \| McNamara, Erin \| Nonomiya, Jim \| Sambrone, Amy \| ... \| Ye, Weilan ACS Medicinal Chemistry Letters, volume 6, issue 8, pages 913-918 (2015). 10.1021/acsmedchemlett.5b00174 Cited by (34) \| Cite \| Source \| Open Access
Discovery of Selective 4-Amino-pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization (journal article) Crawford, Terry D. \| Ndubaku, Chudi O. \| Chen, Huifen \| Boggs, Jason W. \| Bravo, Brandon J. \| DeLaTorre, Kelly \| Giannetti, Anthony M. \| Gould, Stephen E. \| Harris, Seth F. \| Magnuson, Steven R. \| ... \| Ye, Weilan Journal of Medicinal Chemistry, volume 57, issue 8, pages 3484-3493 (2014). 10.1021/jm500155b Cited by (42) \| Cite \| Source
Solvent-based formulations for intravenous mouse pharmacokinetic studies: tolerability and recommended solvent dose limits (journal article) Thackaberry, Evan A. \| Wang, Xiaojing \| Schweiger, Michelle \| Messick, Kirsten \| Valle, Nicole \| Dean, Brian \| Sambrone, Amy \| Bowman, Terri \| Xie, Minli Xenobiotica, volume 44, issue 3, pages 235-241 (2014). 10.3109/00498254.2013.845706 Cited by (32) \| Cite \| Source
A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation–Driven Colorectal Tumor Growth (journal article) Lau, Ted \| Chan, Emily \| Callow, Marinella \| Waaler, Jo \| Boggs, Jason \| Blake, Robert A. \| Magnuson, Steven \| Sambrone, Amy \| Schutten, Melissa \| Firestein, Ron \| ... \| Costa, Mike Cancer Research, volume 73, issue 10, pages 3132-3144 (2013). 10.1158/0008-5472.CAN-12-4562 Cited by (266) \| Cite \| Source \| Open Access
Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF–induced neutrophil recruitment (journal article) Phan, Vernon T. \| Wu, Xiumin \| Cheng, Jason H. \| Sheng, Rebecca X. \| Chung, Alicia S. \| Zhuang, Guanglei \| Tran, Christopher \| Song, Qinghua \| Kowanetz, Marcin \| Sambrone, Amy \| ... \| Ferrara, Napoleone Proceedings of the National Academy of Sciences, volume 110, issue 15, pages 6079-6084 (2013). 10.1073/pnas.1303302110 Cited by (92) \| Cite \| Source \| Open Access
In Vitro and In Vivo Evaluation of Amorphous Solid Dispersions Generated by Different Bench-Scale Processes, Using Griseofulvin as a Model Compound (journal article) Chiang, Po-Chang \| Cui, Yong \| Ran, Yingqing \| Lubach, Joe \| Chou, Kang-Jye \| Bao, Linda \| Jia, Wei \| La, Hank \| Hau, Jonathan \| Sambrone, Amy \| ... \| Wong, Harvey The AAPS Journal, volume 15, issue 2, pages 608-617 (2013). 10.1208/s12248-013-9469-3 Cited by (28) \| Cite \| Source \| Open Access
Evaluation of Drug Load and Polymer by Using a 96-Well Plate Vacuum Dry System for Amorphous Solid Dispersion Drug Delivery (journal article) Chiang, Po-Chang \| Ran, Yingqing \| Chou, Kang-Jye \| Cui, Yong \| Sambrone, Amy \| Chan, Connie \| Hart, Ryan AAPS PharmSciTech, volume 13, issue 2, pages 713-722 (2012). 10.1208/s12249-012-9795-2 Cited by (43) \| Cite \| Source \| Open Access