Gabriela Alexe

ScholarGPS® ID: 21872628345154

Affiliation

Dana-Farber Cancer Institute, Boston, United States

Affiliation History

Field

Medicine

Discipline

Pediatrics

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

6,222

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma (journal article) Malone, Clare F. \| Mabe, Nathaniel W. \| Forman, Alexandra B. \| Alexe, Gabriela \| Engel, Kathleen L. \| Chen, Ying-Jiun C. \| Soeung, Melinda \| Salhotra, Silvi \| Basanthakumar, Allen \| Liu, Bin \| ... \| Stegmaier, Kimberly Science Advances, volume 10, issue 22 (2024). 10.1126/sciadv.adm9449 Cite \| Source
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia (journal article) Lin, Shan \| Schneider, Constanze \| Su, Angela H. \| Alexe, Gabriela \| Root, David E. \| Stegmaier, Kimberly Leukemia, volume 38, issue 3, pages 652-656 (2024). 10.1038/s41375-024-02178-x Cited by (1) \| Cite \| Source
DHODH: a promising target in the treatment of T-cell acute lymphoblastic leukemia (journal article) Sexauer, Amy N. \| Alexe, Gabriela \| Gustafsson, Karin \| Zanetakos, Elizabeth \| Milosevic, Jelena \| Ayres, Mary \| Gandhi, Varsha \| Pikman, Yana \| Stegmaier, Kimberly \| Sykes, David B. Blood Advances, volume 7, issue 21, pages 6685-6701 (2023). 10.1182/bloodadvances.2023010337 Cite \| Source
Identifying Targeted Therapies for CBFA2T3 - GLIS2 Acute Myeloid Leukemia (journal article) Gonzales, Fanny \| Lin, Shan \| Khalid, Delan \| Ellegast, Jana M \| Alexe, Gabriela \| Stegmaier, Kimberly Blood, volume 142, issue Supplement 1, pages 4174-4174 (2023). 10.1182/blood-2023-187187 Cite \| Source
Combining Menin and MEK Inhibition to Target Poor Prognostic KMT2A -Rearranged RAS Pathway-Mutant Acute Leukemia (journal article) Scheidegger, Nastassja \| Alexe, Gabriela \| Khalid, Delan \| Ries, Rhonda E \| Wang, Jim \| Alonzo, Todd A. \| Perry, Jennifer \| Armstrong, Scott A \| Meshinchi, Soheil \| Pikman, Yana \| Stegmaier, Kimberly Blood, volume 142, issue Supplement 1, pages 166-166 (2023). 10.1182/blood-2023-185561 Cited by (2) \| Cite \| Source
The UBE2J2/UBE2K-MARCH5 Ubiquitination Machinery Regulates Apoptosis in Response to Venetoclax in Acute Myeloid Leukemia (journal article) Schneider, Constanze \| Lin, Shan \| Su, Angela H \| Alexe, Gabriela \| Stegmaier, Kimberly Blood, volume 142, issue Supplement 1, pages 2785-2785 (2023). 10.1182/blood-2023-182312 Cite \| Source
Functional Dissection of Cellular Programs to Uncover Novel Gene Dependencies in AML (journal article) Ellegast, Jana M \| Alexe, Gabriela \| Baniya, Subha \| Hamze, Amanda \| Taillon, Audrey \| Adane, Biniam \| Saur Conway, Amy \| Zhang, Tinghu \| Gray, Nathanael S \| Armstrong, Scott A \| Stegmaier, Kimberly Blood, volume 142, issue Supplement 1, pages 1393-1393 (2023). 10.1182/blood-2023-189304 Cite \| Source
Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors (journal article) Malone, Clare F. \| Kim, Minjee \| Alexe, Gabriela \| Engel, Kathleen \| Forman, Alexandra B. \| Robichaud, Amanda \| Conway, Amy Saur \| Goodale, Amy \| Meyer, Ashleigh \| Khalid, Delan \| ... \| Stegmaier, Kimberly Cancer Research, volume 83, issue 2, pages 285-300 (2023). 10.1158/0008-5472.CAN-21-4309 Cited by (4) \| Cite \| Source
P410: COMBINING MENIN AND MEK INHIBITION TO TREAT CHILDREN WITH POOR PROGNOSTIC KMT2A-R RAS-MUTANT ACUTE LEUKEMIA (journal article) Scheidegger, Nastassja \| Alexe, Gabriela \| Khalid, Delan \| Perry, Jennifer \| Armstrong, Scott \| Pikman, Yana \| Stegmaier, Kimberly HemaSphere, volume 7, issue S3, pages e0491723- (2023). 10.1097/01.HS9.0000968548.04917.23 Cite \| Source
DHODH: A Promising New Therapeutic Target in Pediatric T-ALL (journal article) Sexauer, Amy N \| Alexe, Gabriela \| Gandhi, Varsha \| Stegmaier, Kimberly \| Sykes, David Blood, volume 140, issue Supplement 1, pages 7795-7797 (2022). 10.1182/blood-2022-167569 Cite \| Source
Breaking the Pump: Targeting the Sodium-Potassium Pump As a Therapeutic Strategy in Acute Myeloid Leukemia (journal article) Schneider, Constanze \| Spaink, Hermes \| Alexe, Gabriela \| Dharia, Neekesh V. \| Meyer, Ashleigh \| Khalid, Delan \| Scheich, Sebastian \| Häupl, Björn \| Staudt, Louis M. \| Oellerich, Thomas \| Stegmaier, Kimberly Blood, volume 140, issue Supplement 1, pages 4936-4937 (2022). 10.1182/blood-2022-168226 Cite \| Source
Mechanisms of the CBFA2T3-GLIS2 Fusion in AML Maintenance (journal article) Gonzales, Fanny C \| Lin, Shan \| Khalid, Delan \| Ellegast, Jana M \| Alexe, Gabriela \| Stegmaier, Kimberly Blood, volume 140, issue Supplement 1, pages 5864-5865 (2022). 10.1182/blood-2022-166664 Cite \| Source
Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma (journal article) Tokarsky, E. John \| Crow, Jesse C. \| Guenther, Lillian M. \| Sherman, John \| Taslim, Cenny \| Alexe, Gabriela \| Pishas, Kathleen I. \| Rask, Galen \| Justis, Blake S. \| Kasumova, Ana \| ... \| Theisen, Emily R. Molecular Cancer Research, volume 20, issue 7, pages 1035-1046 (2022). 10.1158/1541-7786.MCR-22-0027 Cited by (4) \| Cite \| Source
Breaking the pump: targeting the sodium-potassium pump as a therapeutic strategy in acute myeloid leukemia (conference) Schneider, C \| Spaink, H \| Alexe, G \| Dharia, NV \| Khalid, D \| Scheich, S \| Haeupl, B \| Oellerich, T \| Stegmaier, K 34. Jahrestagung der Kind-Philipp-Stiftung für pädiatrisch onkologische Forschung (2022) Wilsede 10.1055/s-0042-1748706 Cite \| Source
Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy (journal article) Pikman, Yana \| Ocasio-Martinez, Nicole \| Alexe, Gabriela \| Dimitrov, Boris \| Kitara, Samuel \| Diehl, Frances F. \| Robichaud, Amanda L. \| Conway, Amy Saur \| Ross, Linda \| Su, Angela \| ... \| Stegmaier, Kimberly Leukemia, volume 36, issue 2, pages 348-360 (2022). 10.1038/s41375-021-01361-8 Cited by (29) \| Cite \| Source
P455: BREAKING THE PUMP: TARGETING THE SODIUM-POTASSIUM PUMP AS A THERAPEUTIC STRATEGY IN ACUTE MYELOID LEUKEMIA (journal article) Schneider, C. \| Spaink, H. \| Alexe, G. \| Dharia, N. V. \| Khalid, D. \| Scheich, S. \| Haeupl, B. \| Oellerich, T. \| Stegmaier, K. HemaSphere, volume 6 (2022). 10.1097/01.HS9.0000844708.12721.88 Cite \| Source
SLC5A3 Transports Myo-Inositol to Support the Growth of Acute Myeloid Leukemia (journal article) Lin, Shan \| Scheidegger, Nastassja K. \| Alexe, Gabriela \| Seong, Bo Kyung A. \| Dharia, Neekesh V \| Wechsler, Caroline \| Kugener, Guillaume \| Robinchaud, Amanda L \| Conway, Amy \| Adane, Biniam \| ... \| Stegmaier, Kimberly Blood, volume 138, issue Supplement 1, pages 3319-3319 (2021). 10.1182/blood-2021-152023 Cite \| Source
Unleashing Cell-Intrinsic Inflammation As a Strategy to Kill AML Blasts (journal article) Ellegast, Jana M \| Alexe, Gabriela \| Hamze, Amanda \| Lin, Shan \| Pimkin, Maxim \| Ross, Linda \| Dharia, Neekesh V \| Robinchaud, Amanda L \| Conway, Amy \| Khalid, Delan \| ... \| Stegmaier, Kimberly Blood, volume 138, issue Supplement 1, pages 3305-3305 (2021). 10.1182/blood-2021-151511 Cited by (1) \| Cite \| Source
TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma (journal article) Seong, Bo Kyung A. \| Dharia, Neekesh V. \| Lin, Shan \| Donovan, Katherine A. \| Chong, Shasha \| Robichaud, Amanda \| Conway, Amy \| Hamze, Amanda \| Ross, Linda \| Alexe, Gabriela \| ... \| Stegmaier, Kimberly Cancer Cell, volume 39, issue 9, pages 1262-1278.e7 (2021). 10.1016/j.ccell.2021.07.003 Cited by (56) \| Cite \| Source
Resistance Mechanisms to SYK Inhibition in Acute Myeloid Leukemia (journal article) Cremer, Anjali \| Ellegast, Jana M. \| Alexe, Gabriela \| Frank, Elizabeth S. \| Ross, Linda \| Chu, S. Haihua \| Pikman, Yana \| Robichaud, Amanda \| Goodale, Amy \| Häupl, Björn \| ... \| Stegmaier, Kimberly Cancer Discovery, volume 10, issue 2, pages 214-231 (2020). 10.1158/2159-8290.CD-19-0209 Cited by (27) \| Cite \| Source