Mallika Singh

ScholarGPS® ID: 21849595252424

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Medicine

Discipline

Oncology

Top Specialties

Cancer | Neoplasm

Metrics Summary

Publication Count

Predicted Citations

3,276

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth (journal article) Lee, Bianca J. \| Boyer, Jacob A. \| Burnett, G. Leslie \| Thottumkara, Arun P. \| Tibrewal, Nidhi \| Wilson, Stacy L. \| Hsieh, Tientien \| Marquez, Abby \| Lorenzana, Edward G. \| Evans, James W. \| ... \| Rosen, Neal Nature Chemical Biology, volume 17, issue 10, pages 1065-1074 (2021). 10.1038/s41589-021-00813-7 Cited by (36) \| Cite \| Source
Biological markers for identifying patients for treatment with VEGF antagonists (patent) Bais, Carlos \| Brauer, Matthew \| Singh, Mallika \| Schmidt, Maike Patent Number: 10364466 (2019) Cite \| Source
Kras mutant genetically engineered mouse models of human cancers are genomically heterogeneous (journal article) Chung, Wei-Jen \| Daemen, Anneleen \| Cheng, Jason H. \| Long, Jason E. \| Cooper, Jonathan E. \| Wang, Bu-er \| Tran, Christopher \| Singh, Mallika \| Gnad, Florian \| Modrusan, Zora \| ... \| Junttila, Melissa R. Proceedings of the National Academy of Sciences, volume 114, issue 51 (2017). 10.1073/pnas.1708391114 Cited by (48) \| Cite \| Source \| Open Access
Targeting LGR5+ cells with an antibody-drug conjugate for the treatment of colon cancer (journal article) Junttila, Melissa R. \| Mao, Weiguang \| Wang, Xi \| Wang, Bu-Er \| Pham, Thinh \| Flygare, John \| Yu, Shang-Fan \| Yee, Sharon \| Goldenberg, David \| Fields, Carter \| ... \| Polson, Andrew G. Science Translational Medicine, volume 7, issue 314 (2015). 10.1126/scitranslmed.aac7433 Cited by (132) \| Cite \| Source
Modeling Targeted Inhibition of MEK and PI3 Kinase in Human Pancreatic Cancer (journal article) Junttila, Melissa R. \| Devasthali, Vidusha \| Cheng, Jason H. \| Castillo, Joseph \| Metcalfe, Ciara \| Clermont, Anne C. \| Otter, Douglas Den \| Chan, Emily \| Bou-Reslan, Hani \| Cao, Tim \| ... \| Singh, Mallika Molecular Cancer Therapeutics, volume 14, issue 1, pages 40-47 (2015). 10.1158/1535-7163.MCT-14-0030 Cited by (42) \| Cite \| Source \| Open Access
An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth (journal article) Adler, Adam S. \| McCleland, Mark L. \| Yee, Sharon \| Yaylaoglu, Murat \| Hussain, Sofia \| Cosino, Ely \| Quinones, Gabriel \| Modrusan, Zora \| Seshagiri, Somasekar \| Torres, Eric \| ... \| Firestein, Ron Genes & Development, volume 28, issue 10, pages 1068-1084 (2014). 10.1101/gad.237206.113 Cited by (78) \| Cite \| Source \| Open Access
Mouse tumour models to guide drug development and identify resistance mechanisms (journal article) Das Thakur, Meghna \| Pryer, Nancy K \| Singh, Mallika The Journal of Pathology, volume 232, issue 2, pages 103-111 (2014). 10.1002/path.4285 Cited by (25) \| Cite \| Source \| Open Access
Combinations of phosphoinositide 3-kinase inhibitor compounds chemotherapeutic agents, and methods of use (patent) Sampath, Deepak \| Wallin, Jeffrey \| Hoeflich, Klaus \| Johnson, Leisa \| Friedman, Lori \| Singh, Mallika \| Belvin, Marcia \| Patel, Sonal \| Vijapurkar, Ulka Patent Number: 8604014 (2013) Cited by (15) \| Cite \| Source
BIOLOGICAL MARKERS FOR IDENTIFYING PATIENTS FOR TREATMENT WITH VEGF ANTAGONISTS (patent) Bais, Carlos \| Brauer, Matthew J. \| Schmidt, Maike \| Singh, Mallika Patent Number: 20140017233 (2013) Cite \| Source
Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents, and methods of use (patent) Belvin, Marcia \| Friedman, Lori \| Hoeflich, Klaus \| Sampath, Deepak \| Vijapurkar, Ulka \| Wallin, Jeffrey \| Johnson, Leisa \| Singh, Mallika \| Patel, Sonal Patent Number: 8247397 (2012) Cited by (10) \| Cite \| Source
Anti‐VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models (journal article) Singh, Mallika \| Couto, Suzana S \| Forrest, William F \| Lima, Anthony \| Cheng, Jason H \| Molina, Rafael \| Long, Jason E \| Hamilton, Patricia \| McNutt, Angela \| Kasman, Ian \| ... \| Johnson, Leisa The Journal of Pathology, volume 227, issue 4, pages 417-430 (2012). 10.1002/path.4053 Cited by (67) \| Cite \| Source
Modeling and predicting clinical efficacy for drugs targeting the tumor milieu (journal article) Singh, Mallika \| Ferrara, Napoleone Nature Biotechnology, volume 30, issue 7, pages 648-657 (2012). 10.1038/nbt.2286 Cited by (101) \| Cite \| Source
Proapoptotic Activation of Death Receptor 5 on Tumor Endothelial Cells Disrupts the Vasculature and Reduces Tumor Growth (journal article) Wilson, Nicholas S. \| Yang, Annie \| Yang, Becky \| Couto, Suzana \| Stern, Howard \| Gogineni, Alvin \| Pitti, Robert \| Marsters, Scot \| Weimer, Robby M. \| Singh, Mallika \| Ashkenazi, Avi Cancer Cell, volume 22, issue 1, pages 80-90 (2012). 10.1016/j.ccr.2012.05.014 Cited by (49) \| Cite \| Source \| Open Access
Genetically Engineered Mouse Models: Closing the Gap between Preclinical Data and Trial Outcomes (journal article) Singh, Mallika \| Murriel, Christopher L. \| Johnson, Leisa Cancer Research, volume 72, issue 11, pages 2695-2700 (2012). 10.1158/0008-5472.CAN-11-2786 Cited by (109) \| Cite \| Source \| Open Access
Effects of Anti-VEGF Treatment Duration on Tumor Growth, Tumor Regrowth, and Treatment Efficacy (journal article) Bagri, Anil \| Berry, Leanne \| Gunter, Bert \| Singh, Mallika \| Kasman, Ian \| Damico, Lisa A. \| Xiang, Hong \| Schmidt, Maike \| Fuh, Germaine \| Hollister, Beth \| ... \| Plowman, Greg D. Clinical Cancer Research, volume 16, issue 15, pages 3887-3900 (2010). 10.1158/1078-0432.CCR-09-3100 Cited by (118) \| Cite \| Source \| Open Access
Assessing therapeutic responses in Kras mutant cancers using genetically engineered mouse models (journal article) Singh, Mallika \| Lima, Anthony \| Molina, Rafael \| Hamilton, Patricia \| Clermont, Anne C \| Devasthali, Vidusha \| Thompson, Jennifer D \| Cheng, Jason H \| Bou Reslan, Hani \| Ho, Calvin C K \| ... \| Johnson, Leisa Nature Biotechnology, volume 28, issue 6, pages 585-593 (2010). 10.1038/nbt.1640 Cited by (195) \| Cite \| Source
Role of Bv8 in neutrophil-dependent angiogenesis in a transgenic model of cancer progression (journal article) Shojaei, Farbod \| Singh, Mallika \| Thompson, Jennifer D. \| Ferrara, Napoleone Proceedings of the National Academy of Sciences, volume 105, issue 7, pages 2640-2645 (2008). 10.1073/pnas.0712185105 Cited by (262) \| Cite \| Source \| Open Access
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis (journal article) Ridgway, John \| Zhang, Gu \| Wu, Yan \| Stawicki, Scott \| Liang, Wei-Ching \| Chanthery, Yvan \| Kowalski, Joe \| Watts, Ryan J. \| Callahan, Christopher \| Kasman, Ian \| ... \| Yan, Minhong Nature, volume 444, issue 7122, pages 1083-1087 (2006). 10.1038/nature05313 Cited by (890) \| Cite \| Source
Using Genetically Engineered Mouse Models of Cancer to Aid Drug Development: An Industry Perspective (journal article) Singh, Mallika \| Johnson, Leisa Clinical Cancer Research, volume 12, issue 18, pages 5312-5328 (2006). 10.1158/1078-0432.CCR-06-0437 Cited by (78) \| Cite \| Source \| Open Access