Gabriella D'Orazi

ScholarGPS® ID: 20633483990095

Affiliation

National Cancer Institute, National Institutes of Health, Bethesda, United States

Affiliation History

Field

Life Sciences

Discipline

Neurosciences

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

5,448

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Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
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NIH/NSF

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NRF2 activation in BON-1 neuroendocrine cancer cells reduces the cytotoxic effects of a novel Ruthenium(II)-curcumin compound: A pilot study (journal article) Garufi, Alessia \| Pettinari, Riccardo \| Monteonofrio, Laura \| Puliani, Giulia \| Virdia, Ilaria \| Appetecchia, Marialuisa \| Marchetti, Fabio \| Cirone, Mara \| Soddu, Silvia \| D'Orazi, Gabriella Oncology Reports, volume 51, issue 2 (2024). 10.3892/or.2024.8695 Cite \| Source
Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53 (journal article) Romeo, Maria Anele \| Gilardini Montani, Maria Saveria \| Benedetti, Rossella \| Arena, Andrea \| Maretto, Mara \| Bassetti, Erica \| Caiazzo, Rossella \| D'Orazi, Gabriella \| Cirone, Mara Experimental Cell Research, volume 408, issue 2, pages 112879- (2021). 10.1016/j.yexcr.2021.112879 Cited by (8) \| Cite \| Source
Lovastatin reduces PEL cell survival by phosphorylating ERK1 /2 that blocks the autophagic flux and engages a cross‐talk with p53 to activate p21 (journal article) Santarelli, Roberta \| Pompili, Chiara \| Gilardini Montani, Maria Saveria \| Romeo, Maria Anele \| Gonnella, Roberta \| D'Orazi, Gabriella \| Cirone, Mara IUBMB Life, volume 73, issue 7, pages 968-977 (2021). 10.1002/iub.2503 Cited by (6) \| Cite \| Source
PGE2 Released by Pancreatic Cancer Cells Undergoing ER Stress Transfers the Stress to DCs Impairing Their Immune Function (journal article) Gilardini Montani, Maria Saveria \| Benedetti, Rossella \| Piconese, Silvia \| Pulcinelli, Fabio Maria \| Timperio, Anna Maria \| Romeo, Maria Anele \| Masuelli, Laura \| Mattei, Maurizio \| Bei, Roberto \| D'Orazi, Gabriella \| Cirone, Mara Molecular Cancer Therapeutics, volume 20, issue 5, pages 934-945 (2021). 10.1158/1535-7163.MCT-20-0699 Cited by (17) \| Cite \| Source
Nuclear factor erythroid 2 (NF‐E2) p45‐related factor 2 interferes with homeodomain‐interacting protein kinase 2/p53 activity to impair solid tumors chemosensitivity (journal article) D'Orazi, Gabriella \| Garufi, Alessia \| Cirone, Mara IUBMB Life, volume 72, issue 8, pages 1634-1639 (2020). 10.1002/iub.2334 Cited by (6) \| Cite \| Source
STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway (journal article) Romeo, Maria Anele \| Gilardini Montani, Maria Saveria \| Benedetti, Rossella \| Santarelli, Roberta \| D'Orazi, Gabriella \| Cirone, Mara Frontiers in Oncology, volume 10 (2020). 10.3389/fonc.2020.01102 Cited by (22) \| Cite \| Source
HHV-6A infection dysregulates autophagy/UPR interplay increasing beta amyloid production and tau phosphorylation in astrocytoma cells as well as in primary neurons, possible molecular mechanisms linking viral infection to Alzheimer's disease (journal article) Romeo, Maria Anele \| Gilardini Montani, Maria Saveria \| Gaeta, Aurelia \| D'Orazi, Gabriella \| Faggioni, Alberto \| Cirone, Mara Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, volume 1866, issue 3, pages 165647- (2020). 10.1016/j.bbadis.2019.165647 Cited by (24) \| Cite \| Source
HIPK2 role in the tumor–host interaction: Impact on fibroblasts transdifferentiation CAF‐like (journal article) Garufi, Alessia \| Traversi, Gianandrea \| Cirone, Mara \| D'Orazi, Gabriella IUBMB Life, volume 71, issue 12, pages 2055-2061 (2019). 10.1002/iub.2144 Cited by (20) \| Cite \| Source
Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation (journal article) Granato, Marisa \| Gilardini Montani, Maria Saveria \| Romeo, Maria Anele \| Santarelli, Roberta \| Gonnella, Roberta \| D'Orazi, Gabriella \| Faggioni, Alberto \| Cirone, Mara Cellular Signalling, volume 40 (2017). 10.1016/j.cellsig.2017.09.020 Cited by (23) \| Cite \| Source
Chloroquine supplementation increases the cytotoxic effect of curcumin against Her2/neu overexpressing breast cancer cells in vitro and in vivo in nude mice while counteracts it in immune competent mice (journal article) Masuelli, L. \| Granato, M. \| Benvenuto, M. \| Mattera, R. \| Bernardini, R. \| Mattei, M. \| d'Amati, G. \| D'Orazi, G. \| Faggioni, A. \| Bei, R. \| Cirone, M. OncoImmunology, volume 6, issue 11, pages e1356151- (2017). 10.1080/2162402X.2017.1356151 Cited by (44) \| Cite \| Source
Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways (journal article) Granato, Marisa \| Rizzello, Celeste \| Gilardini Montani, Maria Saveria \| Cuomo, Laura \| Vitillo, Marina \| Santarelli, Roberta \| Gonnella, Roberta \| D'Orazi, Gabriella \| Faggioni, Alberto \| Cirone, Mara The Journal of Nutritional Biochemistry, volume 41 (2017). 10.1016/j.jnutbio.2016.12.011 Cited by (184) \| Cite \| Source
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: Involvement in cancer invasion and metastasis (journal article) Cordani, Marco \| Pacchiana, Raffaella \| Butera, Giovanna \| D'Orazi, Gabriella \| Scarpa, Aldo \| Donadelli, Massimo Cancer Letters, volume 376, issue 2, pages 303-309 (2016). 10.1016/j.canlet.2016.03.046 Cited by (55) \| Cite \| Source
ZnCl2 sustains the adriamycin-induced cell death inhibited by high glucose (journal article) Garufi, A \| Trisciuoglio, D \| Cirone, M \| D'Orazi, G Cell Death & Disease, volume 7, issue 6, pages e2280-e2280 (2016). 10.1038/cddis.2016.178 Cited by (14) \| Cite \| Source \| Open Access
High glucose and hyperglycemic sera from type 2 diabetic patients impair DC differentiation by inducing ROS and activating Wnt/β-catenin and p38 MAPK (journal article) Gilardini Montani, Maria Saveria \| Granato, Marisa \| Cuomo, Laura \| Valia, Sandro \| Di Renzo, Livia \| D'Orazi, Gabriella \| Faggioni, Alberto \| Cirone, Mara Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, volume 1862, issue 4, pages 805-813 (2016). 10.1016/j.bbadis.2016.01.001 Cited by (45) \| Cite \| Source \| Open Access
Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies (journal article) Pistritto, Giuseppa \| Trisciuoglio, Daniela \| Ceci, Claudia \| Garufi, Alessia \| D'Orazi, Gabriella Aging, volume 8, issue 4, pages 603-619 (2016). 10.18632/aging.100934 Cited by (1,025) \| Cite \| Source \| Open Access
Hyperglycemia triggers HIPK2 protein degradation. (journal article) Baldari, Silvia \| Garufi, Alessia \| Granato, Marisa \| Cuomo, Laura \| Pistritto, Giuseppa \| Cirone, Mara \| D'Orazi, Gabriella Oncotarget (2016). Cite
Zn(II)-curc targets p53 in thyroid cancer cells (journal article) Garufi, Alessia \| D'ORAZI, Valerio \| Crispini, Alessandra \| D'ORAZI, Gabriella International Journal of Oncology, volume 47, issue 4, pages 1241-1248 (2015). 10.3892/ijo.2015.3125 Cited by (22) \| Cite \| Source \| Open Access
Targeting MKK3 as a novel anticancer strategy: molecular mechanisms and therapeutical implications (journal article) Baldari, S \| Ubertini, V \| Garufi, A \| D'Orazi, G \| Bossi, G Cell Death & Disease, volume 6, issue 1, pages e1621-e1621 (2015). 10.1038/cddis.2014.591 Cited by (41) \| Cite \| Source \| Open Access
Erratum: HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma (journal article) Granato, M \| Lacconi, V \| Peddis, M \| Lotti, L V \| Di Renzo, L \| Gonnella, R \| Santarelli, R \| Trivedi, P \| Frati, L \| D'Orazi, G \| ... \| Cirone, M Cell Death & Disease, volume 5, issue 5, pages e1254-e1254 (2014). 10.1038/cddis.2014.238 Cited by (1) \| Cite \| Source \| Open Access
Zinc supplementation augments in vivo antitumor effect of chemotherapy by restoring p53 function (journal article) Margalit, Ofer \| Simon, Amos J. \| Yakubov, Eduard \| Puca, Rosa \| Yosepovich, Ady \| Avivi, Camila \| Jacob‐Hirsch, Jasmine \| Gelernter, Ilana \| Harmelin, Alon \| Barshack, Iris \| ... \| Amariglio, Ninette International Journal of Cancer, volume 131, issue 4 (2012). 10.1002/ijc.26441 Cited by (50) \| Cite \| Source \| Open Access