Scott Pollack

ScholarGPS® ID: 20060888063162

Affiliation

Merck & Co., Inc., United States

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Chemical Synthesis | Medicinal Chemistry | Alzheimer's Disease

Metrics Summary

Publication Count

Predicted Citations

844

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Synthesis of a Complex and Highly Potent PCSK9 Inhibitor (journal article) Kuethe, Jeffrey T. \| Lee, Joshua \| Thaisrivongs, David \| Yasuda, Nobuyoshi \| Pollack, Scott R. \| Leone, Joseph \| DaSilva, Jimmy \| Biba, Mirlinda \| Tsay, Fuh-Rong \| Regalado, Erik L. \| ... \| Cohen, Ryan Organic Letters, volume 25, issue 27, pages 5001-5005 (2023). 10.1021/acs.orglett.3c01635 Cited by (1) \| Cite \| Source
Total Synthesis of Darobactin A (journal article) Nesic, Marko \| Ryffel, David B. \| Maturano, Jonathan \| Shevlin, Michael \| Pollack, Scott R. \| Gauthier, Donald R. \| Trigo-Mouriño, Pablo \| Zhang, Li-Kang \| Schultz, Danielle M. \| McCabe Dunn, Jamie M. \| ... \| Sarlah, David Journal of the American Chemical Society, volume 144, issue 31, pages 14026-14030 (2022). 10.1021/jacs.2c05891 Cited by (35) \| Cite \| Source
Metal-Free Stereoselective Synthesis of ( E )- and ( Z )-N-Monosubstituted β-Aminoacrylates via Condensation Reactions of Carbamates (journal article) Pollack, Scott R. \| Dion, Amélie The Journal of Organic Chemistry, volume 86, issue 17, pages 11748-11762 (2021). 10.1021/acs.joc.1c01212 Cited by (1) \| Cite \| Source
Evaluation of 5-(Trifluoromethyl)-1,2,4-oxadiazole-Based Class IIa HDAC Inhibitors for Huntington’s Disease (journal article) Stott, Andrew J. \| Maillard, Michel C. \| Beaumont, Vahri \| Allcock, David \| Aziz, Omar \| Borchers, Alexander H. \| Blackaby, Wesley \| Breccia, Perla \| Creighton-Gutteridge, Gillian \| Haughan, Alan F. \| ... \| Dominguez, Celia ACS Medicinal Chemistry Letters, volume 12, issue 3, pages 380-388 (2021). 10.1021/acsmedchemlett.0c00532 Cited by (27) \| Cite \| Source
Chemoselective Reduction of α-Cyano Carbonyl Compounds: Application to the Preparation of Heterocycles (journal article) Pollack, Scott R. \| Kuethe, Jeffrey T. Organic Letters, volume 18, issue 24, pages 6388-6391 (2016). 10.1021/acs.orglett.6b03285 Cited by (19) \| Cite \| Source
Site selective syntheses of [3 H]omeprazole using hydrogen isotope exchange chemistry (journal article) Pollack, Scott R. \| Schenk, David J. Journal of Labelled Compounds and Radiopharmaceuticals, volume 58, issue 11-12, pages 433-441 (2015). 10.1002/jlcr.3346 Cited by (10) \| Cite \| Source
NMR‐based approach to the analysis of radiopharmaceuticals: radiochemical purity, specific activity, and radioactive concentration values by proton and tritium NMR spectroscopy (journal article) Schenk, David J. \| Dormer, Peter G. \| Hesk, David \| Pollack, Scott R. \| Lavey, Carolee Flader Journal of Labelled Compounds and Radiopharmaceuticals, volume 58, issue 7, pages 291-298 (2015). 10.1002/jlcr.3295 Cited by (6) \| Cite \| Source
Development of an automated system for preparation of liquid scintillation counting samples for radiolabeled pharmaceuticals (journal article) Marques, Rosemary \| Bernardoni, Frank \| Pollack, Scott \| Helmy, Roy Journal of Labelled Compounds and Radiopharmaceuticals, volume 57, issue 3, pages 121-124 (2014). 10.1002/jlcr.3156 Cited by (4) \| Cite \| Source
P1–290: In vitro characterization of [3H]‐T808 (tau PET tracer) binding in human brain tissues of Alzheimer's disease (journal article) Zeng, Zhizhen \| Chen, Tsing‐Bau \| Miller, Patricia \| O'Malley, Stacey \| Connolly, Brett \| Bennacef, Idriss \| Selnick, Harold G. \| Pollack, Scott \| Sur, Cyrille \| Hostetler, Eric Alzheimer's & Dementia, volume 9, issue 4S_Part_6 (2013). 10.1016/j.jalz.2013.05.515 Cite \| Source
IC‐P‐174: In vitro characterization of [3H]‐T808 (tau PET tracer) binding in human brain tissues in Alzheimer's disease (journal article) Chen, Tsing‐Bau \| Zeng, Zhizhen \| Miller, Patricia \| O'Malley, Stacey \| Connolly, Brett \| Bennacef, Idriss \| Selnick, Harold G. \| Pollack, Scott \| Sur, Cyrille \| Hostetler, Eric Alzheimer's & Dementia, volume 9, issue 4S_Part_2 (2013). 10.1016/j.jalz.2013.05.171 Cited by (2) \| Cite \| Source
P4‐181: In vitro study on [3H]THK523 binding to brain tissues of Alzheimer's disease (journal article) Zeng, Zhizhen \| Chen, Tsing‐Bau \| Miller, Patricia \| Connolly, Brett \| Selnick, Harold G. \| Pollack, Scott \| Sur, Cyrille \| Hamill, Terence Alzheimer's & Dementia, volume 8, issue 4S_Part_19 (2012). 10.1016/j.jalz.2012.05.1885 Cited by (1) \| Cite \| Source
IC‐P‐122: In vitro study on [3H]THK523 binding to brain tissues of Alzheimer's disease (journal article) Zeng, Zhizhen \| Chen, Tsing‐Bau \| Miller, Patricia \| Connolly, Brett \| Selnick, Harold G. \| Pollack, Scott \| Sur, Cyrille \| Hamill, Terence Alzheimer's & Dementia, volume 8, issue 4S_Part_2 (2012). 10.1016/j.jalz.2012.05.156 Cite \| Source
Asymmetric, biocatalytic labeled compound synthesis using transaminases (journal article) Truppo, Matthew \| Janey, Jacob M. \| Grau, Brendan \| Morley, Krista \| Pollack, Scott \| Hughes, Greg \| Davies, Ian Catalysis Science & Technology, volume 2, issue 8, pages 1556- (2012). 10.1039/c2cy20110k Cited by (16) \| Cite \| Source
Synthesis and structure–activity relationship of 7-azaindole piperidine derivatives as CCR2 antagonists (journal article) Xia, Mingde \| Hou, Cuifen \| DeMong, Duane \| Pollack, Scott \| Pan, Meng \| Singer, Monica \| Matheis, Michele \| Murray, William \| Cavender, Druie \| Wachter, Michael Bioorganic & Medicinal Chemistry Letters, volume 18, issue 24, pages 6468-6470 (2008). 10.1016/j.bmcl.2008.10.061 Cited by (15) \| Cite \| Source
A novel 5-[1,3,4-oxadiazol-2-yl]-N-aryl-4,6-pyrimidine diamine having dual EGFR/HER2 kinase activity: Design, synthesis, and biological activity (journal article) Hughes, Terry V. \| Xu, Guozhang \| Wetter, Steven K. \| Connolly, Peter J. \| Emanuel, Stuart L. \| Karnachi, Prabha \| Pollack, Scott R. \| Pandey, Niranjan \| Adams, Mary \| Moreno-Mazza, Sandra \| ... \| Greenberger, Lee M. Bioorganic & Medicinal Chemistry Letters, volume 18, issue 17, pages 4896-4899 (2008). 10.1016/j.bmcl.2008.07.057 Cited by (23) \| Cite \| Source
Substituted dipiperidine alcohols as potent CCR2 antagonists (journal article) Xia, Mingde \| Hou, Cuifen \| DeMong, Duane \| Pollack, Scott \| Pan, Meng \| Brackley, James \| Singer, Monica \| Matheis, Michele \| Cavender, Druie \| Wachter, Michael Bioorganic & Medicinal Chemistry Letters, volume 18, issue 12, pages 3562-3564 (2008). 10.1016/j.bmcl.2008.05.010 Cited by (13) \| Cite \| Source
Synthesis and biological evaluation of phenyl piperidine derivatives as CCR2 antagonists (journal article) Xia, Mingde \| Hou, Cuifen \| Pollack, Scott \| Brackley, James \| DeMong, Duane \| Pan, Meng \| Singer, Monica \| Matheis, Michele \| Olini, Gil \| Cavender, Druie \| Wachter, Michael Bioorganic & Medicinal Chemistry Letters, volume 17, issue 21, pages 5964-5968 (2007). 10.1016/j.bmcl.2007.07.065 Cited by (10) \| Cite \| Source
Synthesis, Structure−Activity Relationship and in Vivo Antiinflammatory Efficacy of Substituted Dipiperidines as CCR2 Antagonists (journal article) Xia, Mingde \| Hou, Cuifen \| DeMong, Duane E. \| Pollack, Scott R. \| Pan, Meng \| Brackley, James A. \| Jain, Nareshkumar \| Gerchak, Chrissy \| Singer, Monica \| Malaviya, Ravi \| ... \| Wachter, Michael Journal of Medicinal Chemistry, volume 50, issue 23, pages 5561-5563 (2007). 10.1021/jm070902b Cited by (27) \| Cite \| Source
Bromotrimethylsilane (book chapter) In Encyclopedia of Reagents for Organic Synthesis Martinelli, Michael J. \| Pollack, Scott R. John Wiley & Sons, Ltd (2006) 10.1002/047084289X.rb327.pub2 Cited by (2) \| Cite \| Source
Small Molecule Trk Receptor Agonists and Other Neurotrophic Factor Mimetics (journal article) Pollack, Scott \| Harper, Sarah Current Drug Target -CNS & Neurological Disorders, volume 1, issue 1, pages 59-80 (2002). 10.2174/1568007023339490 Cited by (50) \| Cite \| Source