Husseini K. Manji | Scholar Profiles and Rankings

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Non-canonical pathways in the pathophysiology and therapeutics of bipolar disorder (journal article) Machado-Vieira, Rodrigo \| Courtes, Alan C. \| Zarate, Carlos A. \| Henter, Ioline D. \| Manji, Husseini K. Frontiers in Neuroscience, volume 17 (2023). 10.3389/fnins.2023.1228455 Cite \| Source
Comparison of Long-Term Efficacy and Safety of Esketamine Nasal Spray Plus Oral Antidepressant in Younger Versus Older Patients With Treatment-Resistant Depression: Post-Hoc Analysis of SUSTAIN-2, a Long-Term Open-Label Phase 3 Safety and Efficacy Study (journal article) Ochs-Ross, Rachel \| Wajs, Ewa \| Daly, Ella J. \| Zhang, Yun \| Lane, Rosanne \| Lim, Pilar \| Drevets, Wayne C. \| Steffens, David C. \| Sanacora, Gerard \| Jamieson, Carol \| ... \| Singh, Jaskaran B. The American Journal of Geriatric Psychiatry, volume 30, issue 5, pages 541-556 (2022). 10.1016/j.jagp.2021.09.014 Cited by (17) \| Cite \| Source
Immune targets for therapeutic development in depression: towards precision medicine (journal article) Drevets, Wayne C. \| Wittenberg, Gayle M. \| Bullmore, Edward T. \| Manji, Husseini K. Nature Reviews Drug Discovery, volume 21, issue 3, pages 224-244 (2022). 10.1038/s41573-021-00368-1 Cited by (104) \| Cite \| Source
Bag‐1 mediates glucocorticoid receptor trafficking to mitochondria after corticosterone stimulation: Potential role in regulating affective resilience (journal article) Luo, Shaolei \| Hou, Yangyang \| Zhang, Yaping \| Feng, Lei \| Hunter, Richard G. \| Yuan, Peixiong \| Jia, Yue \| Li, Haoran \| Wang, Gang \| K. Manji, Husseini \| ... \| Du, Jing Journal of Neurochemistry, volume 158, issue 2, pages 358-372 (2021). 10.1111/jnc.15211 Cited by (7) \| Cite \| Source
Post hoc analyses of an open-label long-term study of esketamine nasal spray plus an oral antidepressant comparing results in older versus younger adults with treatment-resistant depression (journal article) Ochs-Ross, Rachel \| Wajs, Ewa \| Daly, Ella J. \| Zhang, Yun \| Lane, Rosanne \| Lim, Pilar \| Hough, David \| Manji, Husseini \| Drevets, Wayne C. \| Steffens, David C. \| Singh, Jaskaran B. The American Journal of Geriatric Psychiatry, volume 29, issue 4, pages S127-S128 (2021). 10.1016/j.jagp.2021.01.123 Cited by (2) \| Cite \| Source
Esketamine Nasal Spray for Rapid Reduction of Depressive Symptoms in Patients With Major Depressive Disorder Who Have Active Suicide Ideation With Intent: Results of a Phase 3, Double-Blind, Randomized Study (ASPIRE II) (journal article) Ionescu, Dawn F \| Fu, Dong-Jing \| Qiu, Xin \| Lane, Rosanne \| Lim, Pilar \| Kasper, Siegfried \| Hough, David \| Drevets, Wayne C \| Manji, Husseini \| Canuso, Carla M International Journal of Neuropsychopharmacology, volume 24, issue 1, pages 22-31 (2021). 10.1093/ijnp/pyaa068 Cited by (129) \| Cite \| Source
Mood Stabilizers (book chapter) In Encyclopedia of Molecular Pharmacology Chen, Guang \| Machado-Vieira, Rodrigo \| Zarate, Carlos A. \| Manji, Husseini K. Springer International Publishing (2021) 10.1007/978-3-030-57401-7_10033 Cite \| Source
Mood Stabilizers (book chapter) In Encyclopedia of Molecular Pharmacology Chen, Guang \| Machado-Vieira, Rodrigo \| Zarate, Carlos A. \| Manji, Husseini K. Springer International Publishing (2021) 10.1007/978-3-030-21573-6_10033-1 Cite \| Source
Responsible innovation in technology for mental health care (journal article) Eyre, Harris A \| Ellsworth, William \| Fu, Ernestine \| Manji, Husseini K \| Berk, Michael The Lancet Psychiatry, volume 7, issue 9, pages 728-730 (2020). 10.1016/S2215-0366(20)30192-9 Cited by (7) \| Cite \| Source
Esketamine Nasal Spray for Rapid Reduction of Major Depressive Disorder Symptoms in Patients Who Have Active Suicidal Ideation With Intent (journal article) Fu, Dong-Jing \| Ionescu, Dawn F. \| Li, Xiang \| Lane, Rosanne \| Lim, Pilar \| Sanacora, Gerard \| Hough, David \| Manji, Husseini \| Drevets, Wayne C. \| Canuso, Carla M. The Journal of Clinical Psychiatry, volume 81, issue 3 (2020). 10.4088/JCP.19m13191 Cited by (50) \| Cite \| Source
Esketamine Nasal Spray Plus Oral Antidepressant in Patients With Treatment-Resistant Depression (journal article) Wajs, Ewa \| Aluisio, Leah \| Holder, Richard \| Daly, Ella J. \| Lane, Rosanne \| Lim, Pilar \| George, Joyce E. \| Morrison, Randall L. \| Sanacora, Gerard \| Young, Allan H. \| ... \| Singh, Jaskaran B. The Journal of Clinical Psychiatry, volume 81, issue 3 (2020). 10.4088/JCP.19m12891 Cited by (151) \| Cite \| Source
ASPI: a public–private partnership to develop treatments for autism (journal article) Ness, Seth \| Pandina, Gahan \| Jagannatha, Shyla \| Wathen, Kyle \| Bangerter, Abigail \| Manyakov, Nikolay V. \| Hendren, Robert \| Leventhal, Bennett \| Murphy, Declan \| Dawson, Geraldine \| ... \| Manji, Husseini K. Nature Reviews Drug Discovery, volume 19, issue 4, pages 219-220 (2020). 10.1038/d41573-020-00012-4 Cited by (5) \| Cite \| Source
Efficacy and Safety of Esketamine Nasal Spray Plus an Oral Antidepressant in Elderly Patients With Treatment-Resistant Depression—TRANSFORM-3 (journal article) Ochs-Ross, Rachel \| Daly, Ella J. \| Zhang, Yun \| Lane, Rosanne \| Lim, Pilar \| Morrison, Randall L. \| Hough, David \| Manji, Husseini \| Drevets, Wayne C. \| Sanacora, Gerard \| ... \| Singh, Jaskaran B. The American Journal of Geriatric Psychiatry, volume 28, issue 2, pages 121-141 (2020). 10.1016/j.jagp.2019.10.008 Cited by (182) \| Cite \| Source
Will We Have a Drug for Alzheimer's Disease by 2030? The View From Pharma (journal article) Lovestone, Simon \| Manji, Husseini K. Clinical Pharmacology & Therapeutics, volume 107, issue 1, pages 79-81 (2020). 10.1002/cpt.1685 Cited by (7) \| Cite \| Source
P.607 Esketamine nasal spray for rapid reduction of major depressive disorder symptoms in patients at imminent risk for suicide: ASPIRE-2 study (journal article) Ionescu, D.F. \| Canuso, C.M. \| Fu, D.J. \| Qiu, X. \| Lane, R. \| Lim, P. \| Hough, D. \| Drevets, W. \| Manji, H. European Neuropsychopharmacology, volume 29 (2019). 10.1016/j.euroneuro.2019.09.591 Cited by (2) \| Cite \| Source
P.323 Esketamine nasal spray for rapid reduction of major depressive disorder symptoms in patients at imminent risk for suicide: aspire-1 study (journal article) Fu, D.J. \| Canuso, C.M. \| Ionescu, D.F. \| Li, X. \| Lane, R. \| Lim, P. \| Hough, D. \| Drevets, W. \| Manji, H. European Neuropsychopharmacology, volume 29 (2019). 10.1016/j.euroneuro.2019.09.343 Cited by (1) \| Cite \| Source
P.038 Effect of esketamine nasal spray on cognition in patients with treatment-resistant depression: results from five phase-3 studies (journal article) Morrison, R. \| Singh, J. \| Daly, E. \| Fedgchin, M. \| Wajs, E. \| Alusio, L. \| Ochs-Ross, R. \| Popova, V. \| Karcher, K. \| Lane, R. \| ... \| Manji, H. European Neuropsychopharmacology, volume 29 (2019). 10.1016/j.euroneuro.2019.09.104 Cite \| Source
Efficacy and Safety of Fixed-Dose Esketamine Nasal Spray Combined With a New Oral Antidepressant in Treatment-Resistant Depression: Results of a Randomized, Double-Blind, Active-Controlled Study (TRANSFORM-1) (journal article) Fedgchin, Maggie \| Trivedi, Madhukar \| Daly, Ella J \| Melkote, Rama \| Lane, Rosanne \| Lim, Pilar \| Vitagliano, Dawn \| Blier, Pierre \| Fava, Maurizio \| Liebowitz, Michael \| ... \| Singh, Jaskaran B International Journal of Neuropsychopharmacology, volume 22, issue 10, pages 616-630 (2019). 10.1093/ijnp/pyz039 Cited by (262) \| Cite \| Source
Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression (journal article) Daly, Ella J. \| Trivedi, Madhukar H. \| Janik, Adam \| Li, Honglan \| Zhang, Yun \| Li, Xiang \| Lane, Rosanne \| Lim, Pilar \| Duca, Anna R. \| Hough, David \| ... \| Singh, Jaskaran B. JAMA Psychiatry, volume 76, issue 9, pages 893- (2019). 10.1001/jamapsychiatry.2019.1189 Cited by (345) \| Cite \| Source
Harnessing digital technology to predict, diagnose, monitor, and develop treatments for brain disorders (journal article) Stroud, Clare \| Onnela, Jukka-Pekka \| Manji, Husseini npj Digital Medicine, volume 2, issue 1 (2019). 10.1038/s41746-019-0123-z Cited by (20) \| Cite \| Source

Title	Investigators	Year	Cost	Agency
Role of the p75NTR, LTD and the cholinergic system in mediating coping mechanism	Manji, Husseini	2008	$549,692	NATIONAL INSTITUTE OF MENTAL HEALTH
Roles of kainate receptors in behavioral plasticity related to mood disorders	Manji, Husseini K	2008	$340,064	NATIONAL INSTITUTE OF MENTAL HEALTH
Investigation of NMDA receptor antagonist as antidepressant in animals	Manji, Husseini K	2008	$246,895	NATIONAL INSTITUTE OF MENTAL HEALTH
Glutamatergic Modulators for Rapid &Sustained Antidepressant Effect	Manji, Husseini K	2008	$349,380	NATIONAL INSTITUTE OF MENTAL HEALTH
Antidepressant Efficacy &Safety of AMPAkine (Org 24448) in Major Dep Disorder	Manji, Husseini K	2008	$267,858	NATIONAL INSTITUTE OF MENTAL HEALTH
Testing whether the enzyme GSK-3 is a therapeutically relevant target of lithium	Manji, Husseini K	2008	$177,019	NATIONAL INSTITUTE OF MENTAL HEALTH
Glucocorticoid Receptors (GR) in Mitochondria: The Role in Chronic Stress	Manji, Husseini K	2008	$885,097	NATIONAL INSTITUTE OF MENTAL HEALTH
Neuronal-Glial Interaction in the Treatment of Bipolar Disorder	Manji, Husseini K	2008	$281,833	NATIONAL INSTITUTE OF MENTAL HEALTH
Investigation of Mitochondrial Function in Bipolar Disorder	Manji, Husseini K	2008	$398,294	NATIONAL INSTITUTE OF MENTAL HEALTH
Microarray Studies Identify the Anti-Apoptotic, GR Chap. Protein, BAG-1 in BPD	Manji, Husseini K	2008	$1,120,346	NATIONAL INSTITUTE OF MENTAL HEALTH
AMPA receptor trafficking in the pathophysiology and treatment of mood disorders	Manji, Husseini K	2008	$281,833	NATIONAL INSTITUTE OF MENTAL HEALTH
Efficacy of the Protein Kinase C Inhibitor Tamoxifen in Treatment of Acute Mania	Manji, Husseini K	2008	$142,081	NATIONAL INSTITUTE OF MENTAL HEALTH
Glutamatergic Modulators for Rapid &Sustained Antidepressant Effect	Manji, Husseini K	2007	$271,148	NATIONAL INSTITUTE OF MENTAL HEALTH
Roles of kainate receptors in behavioral plasticity related to mood disorders	Manji, Husseini K	2007	$419,690	NATIONAL INSTITUTE OF MENTAL HEALTH
Investigation of NMDA receptor antagonist as antidepressant in animals	Manji, Husseini K	2007	$580,020	NATIONAL INSTITUTE OF MENTAL HEALTH
Comb Dopamine Agonist &Select Serotonin Reuptake Inhibitor f/Trtmt of Depression	Manji, Husseini K	2007	$341,882	NATIONAL INSTITUTE OF MENTAL HEALTH
Antidepressant Efficacy &Safety of AMPAkine (Org 24448) in Major Dep Disorder	Manji, Husseini K	2007	$271,148	NATIONAL INSTITUTE OF MENTAL HEALTH
A pharmacologic strategy to bring about rapid (next day) antidepressants effects	Manji, Husseini K	2007	$506,928	NATIONAL INSTITUTE OF MENTAL HEALTH
Testing whether the enzyme GSK-3 is a therapeutically relevant target of lithium	Manji, Husseini K	2007	$891,251	NATIONAL INSTITUTE OF MENTAL HEALTH
Glucocorticoid Receptors (GR) in Mitochondria: The Role in Chronic Stress	Manji, Husseini K	2007	$893,609	NATIONAL INSTITUTE OF MENTAL HEALTH
Neuronal-Glial Interaction in the Treatment of Bipolar Disorder	Manji, Husseini K	2007	$518,717	NATIONAL INSTITUTE OF MENTAL HEALTH
Investigation of Mitochondrial Function in Bipolar Disorder	Manji, Husseini K	2007	$872,388	NATIONAL INSTITUTE OF MENTAL HEALTH
Microarray Studies Identify the Anti-Apoptotic, GR Chap. Protein, BAG-1 in BPD	Manji, Husseini K	2007	$697,911	NATIONAL INSTITUTE OF MENTAL HEALTH
AMPA Receptor Subunit GluR1 Synaptic Expression and Trafficking	Manji, Husseini K	2007	$530,506	NATIONAL INSTITUTE OF MENTAL HEALTH
Efficacy of the Protein Kinase C Inhibitor Tamoxifen in Treatment of Acute Mania	Manji, Husseini K	2007	$521,075	NATIONAL INSTITUTE OF MENTAL HEALTH
Antidepressant Efficacy of an Antiglutamatergic Agent in Bipolar Depression	Manji, Husseini K	2007	$334,809	NATIONAL INSTITUTE OF MENTAL HEALTH
Antiglucocorticoid Therapy in Bipolar Depression with Mifepristone (RU486)	Manji, Husseini K	2007	$35,367	NATIONAL INSTITUTE OF MENTAL HEALTH
LITHIUM RESPONSIVE BIPOLAR DISORDER AND CNS MYO INOSITOL	Manji, Husseini K	1999	$324,986	NATIONAL INSTITUTE OF MENTAL HEALTH
PKC SIGNALING AND THE TREATMENT OF BIPOLAR DISORDER	Manji, Husseini K	1999	$153,342	NATIONAL INSTITUTE OF MENTAL HEALTH
PKC SIGNALING AND THE TREATMENT OF BIPOLAR DISORDER	Manji, Husseini K	1998	$148,875	NATIONAL INSTITUTE OF MENTAL HEALTH