Jean-Philippe Stephan

ScholarGPS® ID: 19759619119577

Affiliation

Genentech, Inc., South San Francisco, United States

Affiliation History

Field

Physical Sciences and Mathematics

Discipline

Chemistry

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

5,166

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer (journal article) Viotti, Manuel \| Wilson, Catherine \| McCleland, Mark \| Koeppen, Hartmut \| Haley, Benjamin \| Jhunjhunwala, Suchit \| Klijn, Christiaan \| Modrusan, Zora \| Arnott, David \| Classon, Marie \| ... \| Mellman, Ira Journal of Cell Biology, volume 217, issue 2, pages 763-777 (2018). 10.1083/jcb.201705031 Cited by (31) \| Cite \| Source \| Open Access
Proline Starvation Induces Unresolved ER Stress and Hinders mTORC1-Dependent Tumorigenesis (journal article) Sahu, Nisebita \| Dela Cruz, Darlene \| Gao, Min \| Sandoval, Wendy \| Haverty, Peter M. \| Liu, Jinfeng \| Stephan, Jean-Philippe \| Haley, Benjamin \| Classon, Marie \| Hatzivassiliou, Georgia \| Settleman, Jeff Cell Metabolism, volume 24, issue 5, pages 753-761 (2016). 10.1016/j.cmet.2016.08.008 Cited by (81) \| Cite \| Source
Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs (journal article) Sahu, Nisebita \| Stephan, Jean-Philippe \| Cruz, Darlene Dela \| Merchant, Mark \| Haley, Benjamin \| Bourgon, Richard \| Classon, Marie \| Settleman, Jeff Nature Communications, volume 7, issue 1 (2016). 10.1038/ncomms12351 Cited by (28) \| Cite \| Source \| Open Access
Membrane Display and Functional Analysis of Juxtacrine Ligand-Receptor Signaling (journal article) Nair, Pradeep M. \| Ngu, Hai \| Torres, Eric \| Marsters, Scot \| Lawrence, David A. \| Stephan, Jean-Philippe \| Komuves, Laszlo \| Ashkenazi, Avi BioTechniques, volume 59, issue 4, pages 231-240 (2015). 10.2144/000114342 Cited by (1) \| Cite \| Source \| Open Access
Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway (journal article) Trefely, Sophie \| Khoo, Poh-Sim \| Krycer, James R. \| Chaudhuri, Rima \| Fazakerley, Daniel J. \| Parker, Benjamin L. \| Sultani, Ghazal \| Lee, James \| Stephan, Jean-Philippe \| Torres, Eric \| ... \| Stöckli, Jacqueline Journal of Biological Chemistry, volume 290, issue 43, pages 25834-25846 (2015). 10.1074/jbc.M115.658815 Cited by (44) \| Cite \| Source \| Open Access
Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition (journal article) Wilson, Catherine \| Nicholes, Katrina \| Bustos, Daisy \| Lin, Eva \| Song, Qinghua \| Stephan, Jean-Philippe \| Kirkpatrick, Donald S. \| Settleman, Jeff Oncotarget, volume 5, issue 17 (2014). 10.18632/oncotarget.2397 Cited by (107) \| Cite \| Source \| Open Access
Methods of treating cancer and preventing cancer drug resistance (patent) Classon, Marie \| Stephan, Jean-Philippe Patent Number: 20160160213 (2014) Cite \| Source
Defining the Ligand Specificity of the Deleted in Colorectal Cancer (DCC) Receptor (journal article) Haddick, Patrick C. G. \| Tom, Irene \| Luis, Elizabeth \| Quiñones, Gabriel \| Wranik, Bernd J. \| Ramani, Sree R. \| Stephan, Jean-Philippe \| Tessier-Lavigne, Marc \| Gonzalez, Lino C. PLoS ONE, volume 9, issue 1, pages e84823- (2014). 10.1371/journal.pone.0084823 Cited by (45) \| Cite \| Source \| Open Access
Using RNAi Screening Technologies to Interrogate the Extrinsic Apoptosis Pathway (book chapter) In Regulated Cell Death Part A: Apoptotic Mechanisms Stephan, Jean Philippe Elsevier (2014) 10.1016/B978-0-12-417158-9.00006-6 Cited by (2) \| Cite \| Source
Application of a new wall-less plate technology to complex multistep cell-based investigations using suspension cells (journal article) Quiñones, Gabriel A. \| Moore, Travis I. \| Nicholes, Katrina \| Lee, Hyunjae \| Kim, Sudong \| Sun, Laura \| Jeon, Noo Li \| Stephan, Jean-Philippe Blood, volume 121, issue 7, pages e25-e33 (2013). 10.1182/blood-2012-07-446294 Cited by (4) \| Cite \| Source \| Open Access
TRAF2 Sets a Threshold for Extrinsic Apoptosis by Tagging Caspase-8 with a Ubiquitin Shutoff Timer (journal article) Gonzalvez, Francois \| Lawrence, David \| Yang, Becky \| Yee, Sharon \| Pitti, Robert \| Marsters, Scot \| Pham, Victoria C. \| Stephan, Jean-Philippe \| Lill, Jennie \| Ashkenazi, Avi Molecular Cell, volume 48, issue 6, pages 888-899 (2012). 10.1016/j.molcel.2012.09.031 Cited by (130) \| Cite \| Source \| Open Access
An Integrated Genomic Screen Identifies LDHB as an Essential Gene for Triple-Negative Breast Cancer (journal article) McCleland, Mark L. \| Adler, Adam S. \| Shang, Yonglei \| Hunsaker, Thomas \| Truong, Tom \| Peterson, David \| Torres, Eric \| Li, Li \| Haley, Benjamin \| Stephan, Jean-Philippe \| ... \| Firestein, Ron Cancer Research, volume 72, issue 22, pages 5812-5823 (2012). 10.1158/0008-5472.CAN-12-1098 Cited by (143) \| Cite \| Source \| Open Access
Ultrasensitive detection of cellular protein interactions using bioluminescence resonance energy transfer quantum dot‐based nanoprobes (journal article) Quiñones, Gabriel A. \| Miller, Steven C. \| Bhattacharyya, Sukanta \| Sobek, Daniel \| Stephan, Jean‐Philippe Journal of Cellular Biochemistry, volume 113, issue 7, pages 2397-2405 (2012). 10.1002/jcb.24111 Cited by (18) \| Cite \| Source
Antibodies against the gH/gL/UL128/UL130/UL131 Complex Comprise the Majority of the Anti-Cytomegalovirus (Anti-CMV) Neutralizing Antibody Response in CMV Hyperimmune Globulin (journal article) Fouts, Ashley E. \| Chan, Pamela \| Stephan, Jean-Philippe \| Vandlen, Richard \| Feierbach, Becket Journal of Virology, volume 86, issue 13, pages 7444-7447 (2012). 10.1128/JVI.00467-12 Cited by (186) \| Cite \| Source \| Open Access
Production, characterization and pharmacokinetic properties of antibodies with N-linked Mannose-5 glycans (journal article) Yu, Marcella \| Brown, Darren \| Reed, Chae \| Chung, Shan \| Lutman, Jeff \| Stefanich, Eric \| Wong, Anne \| Stephan, Jean-Philippe \| Bayer, Robert mAbs, volume 4, issue 4, pages 475-487 (2012). 10.4161/mabs.20737 Cited by (176) \| Cite \| Source \| Open Access
Preclinical pharmacokinetics of MFGR1877A, a human monoclonal antibody to FGFR3, and prediction of its efficacious clinical dose for the treatment of t(4;14)-positive multiple myeloma (journal article) Kamath, Amrita V. \| Lu, Dan \| Gupta, Priyanka \| Jin, Denise \| Xin, Yan \| Brady, Ann \| Stephan, Jean-Philippe \| Li, Hao \| Tien, Janet \| Qing, Jing \| Damico-Beyer, Lisa A. Cancer Chemotherapy and Pharmacology, volume 69, issue 4, pages 1071-1078 (2012). 10.1007/s00280-011-1807-5 Cited by (21) \| Cite \| Source
Highly specific off-target binding identified and eliminated during the humanization of an antibody against FGF receptor 4 (journal article) Bumbaca, Daniela \| Wong, Anne \| Drake, Elizabeth \| Reyes, Arthur E. \| Lin, Benjamin C. \| Stephan, Jean-Philippe \| Desnoyers, Luc \| Shen, Ben-Quan \| Dennis, Mark S. mAbs, volume 3, issue 4, pages 376-386 (2011). 10.4161/mabs.3.4.15786 Cited by (84) \| Cite \| Source \| Open Access
Challenges in Developing Bioanalytical Assays for Characterization of Antibody–Drug Conjugates (journal article) Stephan, Jean Philippe \| Kozak, Katherine R \| Wong, Wai Lee T Bioanalysis, volume 3, issue 6, pages 677-700 (2011). 10.4155/bio.11.30 Cited by (69) \| Cite \| Source
Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma (journal article) Polson, A G \| Williams, M \| Gray, A M \| Fuji, R N \| Poon, K A \| McBride, J \| Raab, H \| Januario, T \| Go, M \| Lau, J \| ... \| Ebens, A Leukemia, volume 24, issue 9, pages 1566-1573 (2010). 10.1038/leu.2010.141 Cited by (81) \| Cite \| Source \| Open Access
PRO9907 antibodies (patent) Baker, Kevin P. \| Desnoyers, Luc \| Gerritsen, Mary E. \| Goddard, Audrey \| Godowski, Paul J. \| Grimaldi, J. Christopher \| Gurney, Austin L. \| Smith, Victoria \| Stephan, Jean-Philippe F. \| Watanabe, Colin K. \| Wood, William I. Patent Number: 7777007 (2010) Cite \| Source