Michael N. Greco

ScholarGPS® ID: 19151309956796

Affiliation

Johnson & Johnson, New Brunswick, New Jersey, United States

Affiliation History

Field

Life Sciences

Discipline

Biochemistry

Top Specialties

Chemical Synthesis | Medicinal Chemistry | Organic Synthesis | Organic Chemistry

Metrics Summary

Publication Count

Predicted Citations

1,065

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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6-Benzhydryl-4-amino-quinolin-2-ones as Potent Cannabinoid Type 1 (CB1 ) Receptor Inverse Agonists and Chemical Modifications for Peripheral Selectivity (journal article) Zhang, Yue-Mei \| Greco, Michael N. \| Macielag, Mark J. \| Teleha, Christopher A. \| DesJarlais, Renee L. \| Tang, Yuting \| Ho, George \| Hou, Cuifen \| Chen, Cailin \| Zhao, Shuyuan \| ... \| Leonard, James Journal of Medicinal Chemistry, volume 61, issue 22, pages 10276-10298 (2018). 10.1021/acs.jmedchem.8b01467 Cited by (13) \| Cite \| Source
A thiocarbamate inhibitor of endothelial lipase raises HDL cholesterol levels in mice (journal article) Greco, M.N. \| Connelly, M.A. \| Leo, G.C. \| Olson, M.W. \| Powell, E. \| Huang, Z. \| Hawkins, M. \| Smith, C. \| Schalk-Hihi, C. \| Darrow, A.L. \| ... \| Hlasta, D.J. Bioorganic & Medicinal Chemistry Letters, volume 23, issue 9, pages 2595-2597 (2013). 10.1016/j.bmcl.2013.02.113 Cited by (8) \| Cite \| Source
Potency variation of small-molecule chymase inhibitors across species (journal article) Kervinen, Jukka \| Crysler, Carl \| Bayoumy, Shariff \| Abad, Marta C. \| Spurlino, John \| Deckman, Ingrid \| Greco, Michael N. \| Maryanoff, Bruce E. \| de Garavilla, Lawrence Biochemical Pharmacology, volume 80, issue 7, pages 1033-1041 (2010). 10.1016/j.bcp.2010.06.014 Cited by (24) \| Cite \| Source
Dual Inhibition of Cathepsin G and Chymase Is Effective in Animal Models of Pulmonary Inflammation (journal article) Maryanoff, Bruce E. \| de Garavilla, Lawrence \| Greco, Michael N. \| Haertlein, Barbara J. \| Wells, Grace I. \| Andrade-Gordon, Patricia \| Abraham, William M. American Journal of Respiratory and Critical Care Medicine, volume 181, issue 3, pages 247-253 (2010). 10.1164/rccm.200904-0627OC Cited by (53) \| Cite \| Source
Discovery of Potent, Selective, Orally Active, Nonpeptide Inhibitors of Human Mast Cell Chymase (journal article) Greco, Michael N. \| Hawkins, Michael J. \| Powell, Eugene T. \| Almond,, Harold R. \| de Garavilla, Lawrence \| Hall, Jeffrey \| Minor, Lisa K. \| Wang, Yuanping \| Corcoran, Thomas W. \| Di Cera, Enrico \| ... \| Maryanoff, Bruce E. Journal of Medicinal Chemistry, volume 50, issue 8, pages 1727-1730 (2007). 10.1021/jm0700619 Cited by (57) \| Cite \| Source
Facile Dephosphonylation of β-Ketophosphonic Acids: Mechanistic Studies (journal article) Hawkins, Michael J. \| Powell, Eugene T. \| Leo, Gregory C. \| Gauthier, Diane A. \| Greco, Michael N. \| Maryanoff, Bruce Organic Letters, volume 8, issue 16, pages 3429-3431 (2006). 10.1021/ol060519l Cited by (8) \| Cite \| Source
A Novel, Potent Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase (journal article) de Garavilla, Lawrence \| Greco, Michael N. \| Sukumar, Narayanasami \| Chen, Zhi-Wei \| Pineda, Agustin O. \| Mathews, F. Scott \| Di Cera, Enrico \| Giardino, Edward C. \| Wells, Grace I. \| Haertlein, Barbara J. \| ... \| Maryanoff, Bruce E. Journal of Biological Chemistry, volume 280, issue 18, pages 18001-18007 (2005). 10.1074/jbc.M501302200 Cited by (77) \| Cite \| Source \| Open Access
Synthesis and biological evaluation of novel indoloazepine derivatives as non-peptide vasopressin V2 receptor antagonists (journal article) Matthews, Jay M \| Greco, Michael N \| Hecker, Leonard R \| Hoekstra, William J \| Andrade-Gordon, Patricia \| Garavilla, Lawrence de \| Demarest, Keith T \| Ericson, Eric \| Gunnet, Joseph W \| Hageman, William \| ... \| Maryanoff, Bruce E Bioorganic & Medicinal Chemistry Letters, volume 13, issue 4, pages 753-756 (2003). 10.1016/S0960-894X(02)01059-4 Cited by (28) \| Cite \| Source
Structure−Activity Studies on Anticonvulsant Sugar Sulfamates Related to Topiramate. Enhanced Potency with Cyclic Sulfate Derivatives. (journal article) Maryanoff, Bruce E. \| Costanzo, Michael J. \| Nortey, Samuel O. \| Greco, Michael N. \| Shank, Richard P. \| Schupsky, James J. \| Ortegon, Marta P. \| Vaught, Jeffry L. Journal of Medicinal Chemistry, volume 46, issue 4, pages 652-652 (2003). 10.1021/jm020527h Cited by (1) \| Cite \| Source \| Open Access
Nonpeptide Inhibitors of Cathepsin G: Optimization of a Novel β-Ketophosphonic Acid Lead by Structure-Based Drug Design (journal article) Greco, Michael N. \| Hawkins, Michael J. \| Powell, Eugene T. \| Almond,, Harold R. \| Corcoran, Thomas W. \| de Garavilla, Lawrence \| Kauffman, Jack A. \| Recacha, Rosario \| Chattopadhyay, Debashish \| Andrade-Gordon, Patricia \| Maryanoff, Bruce E. Journal of the American Chemical Society, volume 124, issue 15, pages 3810-3811 (2002). 10.1021/ja017506h Cited by (40) \| Cite \| Source
Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design. (journal article) Greco, Michael N \| Hawkins, Michael J \| Powell, Eugene T \| Almond, Harold R \| Corcoran, Thomas W \| de Garavilla, Lawrence \| Kauffman, Jack A \| Recacha, Rosario \| Chattopadhyay, Debashish \| Andrade-Gordon, Patricia \| Maryanoff, Bruce E Journal of the American Chemical Society, volume 124, issue 15 (2002). Cited by (1) \| Cite
Allylmagnesium Bromide-Copper(I) Iodide (book chapter) In Encyclopedia of Reagents for Organic Synthesis Greco, Michael N. John Wiley & Sons, Ltd (2001) 10.1002/047084289X.ra058 Cite \| Source
Ethylmagnesium Bromide-Copper(I) Iodide (book chapter) In Encyclopedia of Reagents for Organic Synthesis Greco, Michael N. John Wiley & Sons, Ltd (2001) 10.1002/047084289X.re101 Cite \| Source
2-Propenylmagnesium Bromide-Copper(I) Iodide (book chapter) In Encyclopedia of Reagents for Organic Synthesis Greco, Michael N. John Wiley & Sons, Ltd (2001) 10.1002/047084289X.rp268 Cite \| Source
2-(3-Trimethylsilyl-1-propenyl)magnesium Bromide-Copper(I) Iodide (book chapter) In Encyclopedia of Reagents for Organic Synthesis Greco, Michael N. John Wiley & Sons, Ltd (2001) 10.1002/047084289X.rt334 Cite \| Source
1-(Trimethylsilyl)vinylmagnesium Bromide-Copper(I) Iodide (book chapter) In Encyclopedia of Reagents for Organic Synthesis Greco, Michael N. John Wiley & Sons, Ltd (2001) 10.1002/047084289X.rt344 Cite \| Source
Vinylmagnesium Bromide-Copper(I) Iodide (book chapter) In Encyclopedia of Reagents for Organic Synthesis Greco, Michael N. John Wiley & Sons, Ltd (2001) 10.1002/047084289X.rv017 Cite \| Source
Structure−Activity Studies on Anticonvulsant Sugar Sulfamates Related to Topiramate. Enhanced Potency with Cyclic Sulfate Derivatives (journal article) Maryanoff, Bruce E. \| Costanzo, Michael J. \| Nortey, Samuel O. \| Greco, Michael N. \| Shank, Richard P. \| Schupsky, James J. \| Ortegon, Marta P. \| Vaught, Jeffry L. Journal of Medicinal Chemistry, volume 41, issue 8, pages 1315-1343 (1998). 10.1021/jm970790w Cited by (104) \| Cite \| Source
Solid-Phase Synthesis of Arginine-Containing Peptides by Guanidine Attachment to a Sulfonyl Linker (journal article) Zhong, H. Marlon \| Greco, Michael N. \| Maryanoff, Bruce E. The Journal of Organic Chemistry, volume 62, issue 26, pages 9326-9330 (1997). 10.1021/jo970736n Cited by (39) \| Cite \| Source
Novel thrombin inhibitors that are based on a macrocyclic tripeptide motif (journal article) Greco, Michael N. \| Powell, Eugene T. \| Hecker, Leonard R. \| Andrade-Gordon, Patricia \| Kauffman, Jack A. \| Lewis, Joan M. \| Ganesh, Venkatapathy \| Tulinsky, Alexander \| Maryanoff, Bruce E. Bioorganic & Medicinal Chemistry Letters, volume 6, issue 24, pages 2947-2952 (1996). 10.1016/S0960-894X(96)00554-9 Cited by (16) \| Cite \| Source