George F. Koob | Scholar Profiles and Rankings

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NIH/NSF


Understanding Hyperkatifeia to Inform Treatment for Alcohol Use Disorder: An Assessment of the National Institute on Alcohol Abuse and Alcoholism Research Portfolio (journal article) Patterson, Jenica Tapocik \| Koob, George F. \| Anderson, Rachel I. Biological Psychiatry, volume 91, issue 12, pages e53-e59 (2022). 10.1016/j.biopsych.2022.02.011 Cited by (3) \| Cite \| Source
Anhedonia, Hyperkatifeia, and Negative Reinforcement in Substance Use Disorders (book chapter) In Anhedonia: Preclinical, Translational, and Clinical Integration Koob, George F. Springer International Publishing (2022) 10.1007/7854_2021_288 Cited by (10) \| Cite \| Source
Brain Disease Model of Addiction (book chapter) In Evaluating the Brain Disease Model of Addiction Volkow, Nora D. \| Koob, George Routledge (2022) 10.4324/9781003032762-14 Cite \| Source
Neurobiologic Advances from the Brain Disease Model of Addiction (book chapter) In Evaluating the Brain Disease Model of Addiction Volkow, Nora D. \| Koob, George F. \| McLellan, A. Thomas Routledge (2022) 10.4324/9781003032762-5 Cited by (2) \| Cite \| Source
Neurocircuitry basis of the opioid use disorder–post-traumatic stress disorder comorbid state: conceptual analyses using a dimensional framework (journal article) Upadhyay, Jaymin \| Verrico, Christopher D \| Cay, Mariesa \| Kodele, Sanda \| Yammine, Luba \| Koob, George F \| Schreiber, Rudy The Lancet Psychiatry, volume 9, issue 1, pages 84-96 (2022). 10.1016/S2215-0366(21)00008-0 Cited by (5) \| Cite \| Source
Choosing appropriate language to reduce the stigma around mental illness and substance use disorders (journal article) Volkow, Nora D. \| Gordon, Joshua A. \| Koob, George F. Neuropsychopharmacology, volume 46, issue 13, pages 2230-2232 (2021). 10.1038/s41386-021-01069-4 Cited by (33) \| Cite \| Source
Nutritional Ketosis as a Potential Treatment for Alcohol Use Disorder (journal article) Mahajan, Vikrant R. \| Elvig, Sophie K. \| Vendruscolo, Leandro F. \| Koob, George F. \| Darcey, Valerie L. \| King, M. Todd \| Kranzler, Henry R. \| Volkow, Nora D. \| Wiers, Corinde E. Frontiers in Psychiatry, volume 12 (2021). 10.3389/fpsyt.2021.781668 Cited by (10) \| Cite \| Source
Vulnerability to substance abuse: A consideration of allostatic loading factors (journal article) O'Dell, Laura E. \| Koob, George F. \| Nazarian, Arbi Neuropharmacology, volume 199 (2021). 10.1016/j.neuropharm.2021.108767 Cite \| Source
Remembering Mary Jeanne Kreek and her many contributions to addiction science (journal article) Volkow, Nora D. \| Koob, George F. Nature Neuroscience, volume 24, issue 7, pages 899-900 (2021). 10.1038/s41593-021-00863-z Cited by (2) \| Cite \| Source
Accelerated Aging of the Amygdala in Alcohol Use Disorders: Relevance to the Dark Side of Addiction (journal article) Tomasi, Dardo \| Wiers, Corinde E \| Manza, Peter \| Shokri-Kojori, Ehsan \| Michele-Vera, Yonga \| Zhang, Rui \| Kroll, Danielle \| Feldman, Dana \| McPherson, Katherine \| Biesecker, Catherine \| ... \| Volkow, Nora D Cerebral Cortex, volume 31, issue 7, pages 3254-3265 (2021). 10.1093/cercor/bhab006 Cited by (8) \| Cite \| Source
κ-Opioid receptor antagonism reverses heroin withdrawal-induced hyperalgesia in male and female rats (journal article) Marchette, Renata C.N. \| Gregory-Flores, Adriana \| Tunstall, Brendan J. \| Carlson, Erika R. \| Jackson, Shelley N. \| Sulima, Agnieszka \| Rice, Kenner C. \| Koob, George F. \| Vendruscolo, Leandro F. Neurobiology of Stress, volume 14 (2021). 10.1016/j.ynstr.2021.100325 Cited by (10) \| Cite \| Source
Samidorphan, an opioid receptor antagonist, attenuates drug-induced increases in extracellular dopamine concentrations and drug self-administration in male Wistar rats (journal article) Cunningham, Jacobi I. \| Todtenkopf, Mark S. \| Dean, Reginald L. \| Azar, Marc R. \| Koob, George F. \| Deaver, Daniel R. \| Eyerman, David J. Pharmacology Biochemistry and Behavior, volume 204 (2021). 10.1016/j.pbb.2021.173157 Cited by (2) \| Cite \| Source
Glucocorticoid receptor modulators decrease alcohol self-administration in male rats (journal article) McGinn, M. Adrienne \| Tunstall, Brendan J. \| Schlosburg, Joel E. \| Gregory-Flores, Adriana \| George, Olivier \| de Guglielmo, Giordano \| Mason, Barbara J. \| Hunt, Hazel J. \| Koob, George F. \| Vendruscolo, Leandro F. Neuropharmacology, volume 188 (2021). 10.1016/j.neuropharm.2021.108510 Cited by (16) \| Cite \| Source
Tolerance to alcohol: A critical yet understudied factor in alcohol addiction (journal article) Elvig, Sophie K. \| McGinn, M. Adrienne \| Smith, Caroline \| Arends, Michael A. \| Koob, George F. \| Vendruscolo, Leandro F. Pharmacology Biochemistry and Behavior, volume 204 (2021). 10.1016/j.pbb.2021.173155 Cited by (18) \| Cite \| Source
Cues conditioned to withdrawal and negative reinforcement: Neglected but key motivational elements driving opioid addiction (journal article) Pantazis, Caroline B. \| Gonzalez, Luis A. \| Tunstall, Brendan J. \| Carmack, Stephanie A. \| Koob, George F. \| Vendruscolo, Leandro F. Science Advances, volume 7, issue 15 (2021). 10.1126/sciadv.abf0364 Cited by (24) \| Cite \| Source
Brain ethanol metabolism by astrocytic ALDH2 drives the behavioural effects of ethanol intoxication (journal article) Jin, Shiyun \| Cao, Qi \| Yang, Fanghan \| Zhu, Hongying \| Xu, Su \| Chen, Qi \| Wang, Ziyi \| Lin, Yuhong \| Cinar, Resat \| Pawlosky, Robert J. \| ... \| Zhang, Li Nature Metabolism, volume 3, issue 3, pages 337-351 (2021). 10.1038/s42255-021-00357-z Cited by (42) \| Cite \| Source
The future of translational research on alcohol use disorder (journal article) Ray, Lara A. \| Grodin, Erica N. \| Leggio, Lorenzo \| Bechtholt, Anita J. \| Becker, Howard \| Feldstein Ewing, Sarah W. \| Jentsch, James David \| King, Andrea C. \| Mason, Barbara J. \| O'Malley, Stephanie \| ... \| Koob, George F. Addiction Biology, volume 26, issue 2 (2021). 10.1111/adb.12903 Cited by (16) \| Cite \| Source
A Basolateral Amygdala Microcircuit for Drug Craving: Is There a Craving Engram? (journal article) Koob, George F. Biological Psychiatry, volume 89, issue 4, pages 323-325 (2021). 10.1016/j.biopsych.2020.11.008 Cited by (2) \| Cite \| Source
Drug Addiction: Hyperkatifeia/Negative Reinforcement as a Framework for Medications Development (journal article) Koob, George F. Pharmacological Reviews, volume 73, issue 1, pages 163-201 (2021). 10.1124/pharmrev.120.000083 Cited by (115) \| Cite \| Source
Allostasis theory in opioid tolerance (journal article) Ballantyne, Jane C. \| Koob, George F. Pain, volume 162, issue 9, pages 2315-2319 (2021). 10.1097/j.pain.0000000000002280 Cited by (6) \| Cite \| Source

Title	Investigators	Year	Expiration	Amount
US-France Cooperative Research: Corticotropin Releasing Factor and Behavior/Mechanism of Action	Bloom, Floyd \| Koob, George	04-01-1989	09-30-1992	$9,450
Arginine Vasopressin and Oxytocin: Behavioral and Physiological Mechanisms of Action	Bloom, Floyd \| Koob, George	06-15-1986	11-30-1989	$10,000
Arginine Vasopressin: Behavioral and Physiological Mechanisms of Action	Koob, George	01-01-1983	06-30-1986	$13,200

Title	Investigators	Year	Cost	Agency
Neurobiology of Addiction	Koob, George	2019	$1,360,000	NATIONAL INSTITUTE ON DRUG ABUSE
Neurobiology of Addiction	Koob, George	2018	$1,360,000	NATIONAL INSTITUTE ON DRUG ABUSE
Neurobiology of Addiction	Koob, George	2017	$1,360,000	NATIONAL INSTITUTE ON DRUG ABUSE
Neurobiology of Addiction	Koob, George	2016	$1,360,000	NATIONAL INSTITUTE ON DRUG ABUSE
Neurobiology of Addiction	Koob, George	2015	$1,359,567	NATIONAL INSTITUTE ON DRUG ABUSE
CNS Effects of Alcohol: Cellular Neurobiology	Koob, George F	2013	$1,786,839	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Administrative Core	Koob, George F	2013	$78,879	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Animal Models Core	Koob, George F	2013	$279,278	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Education Component	Koob, George F	2013	$100,198	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Pilot Component	Koob, George F	2013	$102,331	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Neuronal Substrates of Cocaine Reward	Koob, George F	2013	$99,999	NATIONAL INSTITUTE ON DRUG ABUSE
Neuronal Substrates of Cocaine Reward	Koob, George F	2013	$10,800	NATIONAL INSTITUTE ON DRUG ABUSE
CNS Effects of Alcohol: Cellular Neurobiology	Koob, George F	2012	$1,686,668	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Central mechanisms of nicotine reinforcement and dependence	Koob, George F	2012	$367,630	NATIONAL INSTITUTE ON DRUG ABUSE
Neuronal Substrates of Cocaine Reward	Koob, George F	2012	$368,406	NATIONAL INSTITUTE ON DRUG ABUSE
Effects of Deep Brain Stimulation on Compulsive Drug Intake	Koob, George F	2012	$213,188	NATIONAL INSTITUTE ON DRUG ABUSE
Neuropharmacology of Ethanol Reinforcement	Koob, George F	2012	$429,178	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Neuropsychopharmacology - Multidisciplinary Training	Koob, George F	2012	$394,492	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
The Role of Brain Stress Systems in the Prefrontal Cortex in Compulsive Drinking	Koob, George F	2012	$379,800	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Integrative Neuroscience Initiative on Alcoholism	Koob, George F	2012	$1,172,790	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Component 10: Education	Koob, George F	2012	$87,214	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Component 11: Pilot	Koob, George F	2012	$264,448	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Component 3: Animal Core	Koob, George F	2012	$189,591	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Component 2: Administravtive Core	Koob, George F	2012	$283,868	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Neuronal Substrates of Cocaine Reward	Koob, George F	2011	$368,406	NATIONAL INSTITUTE ON DRUG ABUSE
CNS Effects of Alcohol: Cellular Neurobiology	Koob, George F	2011	$1,737,548	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Central mechanisms of nicotine reinforcement and dependence	Koob, George F	2011	$367,630	NATIONAL INSTITUTE ON DRUG ABUSE
Dopamine Partial Agonists and Psychostimulant Dependence	Koob, George F	2011	$357,428	NATIONAL INSTITUTE ON DRUG ABUSE
Neuropharmacology of Ethanol Reinforcement	Koob, George F	2011	$429,178	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Neurpsychopharmacology-Multidisciplinary Training	Koob, George F	2011	$419,714	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Effects of Deep Brain Stimulation on Compulsive Drug Intake	Koob, George F	2011	$248,450	NATIONAL INSTITUTE ON DRUG ABUSE
The Role of Brain Stress Systems in the Prefrontal Cortex in Compulsive Drinking	Koob, George F	2011	$379,800	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Component 10: Education	Koob, George F	2011	$107,382	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Component 11: Pilot	Koob, George F	2011	$286,354	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Component 3: Animal Core	Koob, George F	2011	$210,107	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Component 2: Administravtive Core	Koob, George F	2011	$305,963	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Integrative Neuroscience Initiative on Alcoholism	Koob, George F	2011	$1,185,912	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Neuropharmacology of Ethanol Reinforcement	Koob, George F	2011	$28,425	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
CNS Effects of Alcohol: Cellular Neurobiology	Koob, George F	2010	$1,807,505	NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
Central mechanisms of nicotine reinforcement and dependence	Koob, George F	2010	$375,210	NATIONAL INSTITUTE ON DRUG ABUSE