Kevin D. Kreutter

ScholarGPS® ID: 15151440533809

Affiliation
Nimbus Therapeutics
Affiliation History

Field
Physical Sciences and Mathematics
Discipline
Chemistry
Top Specialties
Medicinal Chemistry | Tyrosine Kinase | Electron Deficiency
Metrics Summary
Publication Count
41
Predicted Citations
454
Predicted h-index
13
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Discovery and characterization of novel inhibitors of CTP synthase 1 (CTPS1) for the treatment of autoimmune and inflammatory disease (journal article)
McElwee, Joshua J | Kaila, Neelu | Carreiro, Samantha | Kumar, Sheetal | Toms, Angela V | Phadke, Avinash | Jacques, Suzanne | Caravella, Justin A | Kreutter, Kevin | Campos, Sebastien | ... | Tummino, Peter
The Journal of Immunology, volume 210, issue 1_Supplement, pages 165.16-165.16 (2023).
10.4049/jimmunol.210.Supp.165.16
Cited by (1) | Cite | Source
Structural basis for isoform-specific inhibition of human CTPS1 (journal article)
Lynch, Eric M. | DiMattia, Michael A. | Albanese, Steven | van Zundert, Gydo C. P. | Hansen, Jesse M. | Quispe, Joel D. | Kennedy, Madison A. | Verras, Andreas | Borrelli, Kenneth | Toms, Angela V. | ... | Kollman, Justin M.
Proceedings of the National Academy of Sciences, volume 118, issue 40 (2021).
10.1073/pnas.2107968118
Cited by (23) | Cite | Source
Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity (journal article)
Tichenor, Mark S. | Wiener, John J. M. | Rao, Navin L. | Pooley Deckhut, Charlotte | Barbay, J. Kent | Kreutter, Kevin D. | Bacani, Genesis M. | Wei, Jianmei | Chang, Leon | Murrey, Heather E. | ... | Edwards, James P.
ACS Medicinal Chemistry Letters, volume 12, issue 5, pages 782-790 (2021).
10.1021/acsmedchemlett.1c00044
Cited by (8) | Cite | Source
Inhibitors of Bruton's tyrosine kinase and methods of their use (patent)
Arora, Nidhi | Bacani, Genesis M. | Barbay, Joseph Kent | Bembenek, Scott D. | Cai, Min | Chen, Wei | Deckhut, Charlotte Pooley | Edwards, James P. | Ghosh, Brahmananda | Hao, Baoyu | ... | Xiao, Kun
Patent Number: 10822348 (2020)
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Inhibitors of Bruton's tyrosine kinase and method of their use (patent)
Arora, Nidhi | Bacani, Genesis M. | Barbay, Joseph Kent | Bembenek, Scott D. | Cai, Min | Chen, Wei | Deckhut, Charlotte Pooley | Edwards, James P. | Ghosh, Brahmananda | Hao, Baoyu | ... | Xiao, Kun
Patent Number: 10800792 (2020)
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Inhibitors of Bruton's tyrosine kinase and method of their use (patent)
Arora, Nidhi | Bacani, Genesis M. | Barbay, Joseph Kent | Bembenek, Scott D. | Cai, Min | Chen, Wei | Deckhut, Charlotte Pooley | Edwards, James P. | Ghosh, Brahmananda | Kreutter, Kevin D. | ... | Zhu, Yaoping
Patent Number: 10717745 (2020)
Cite | Source
Inhibitors of Bruton's tyrosine kinase and methods of their use (patent)
Arora, Nidhi | Bacani, Genesis M. | Barbay, Joseph Kent | Bembenek, Scott D. | Cai, Min | Chen, Wei | Deckhut, Charlotte Pooley | Edwards, James P. | Ghosh, Brahmananda | Hao, Baoyu | ... | Xiao, Kun
Patent Number: 10689396 (2020)
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Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease (journal article)
Leonard, Kristi A. | Madge, Lisa A. | Krawczuk, Paul J. | Wang, Aihua | Kreutter, Kevin D. | Bacani, Genesis M. | Chai, Wenying | Smith, Russell C. | Tichenor, Mark S. | Harris, Michael C. | ... | Koudriakova, Tatiana
Journal of Medicinal Chemistry, volume 63, issue 6, pages 2915-2929 (2020).
10.1021/acs.jmedchem.9b01439
Cited by (14) | Cite | Source
Alkyl linked quinolinyl modulators of RORγt (patent)
Leonard, Kristi A. | Barbay, Kent | Edwards, James P. | Kreutter, Kevin D. | Kummer, David A. | Maharoof, Umar | Nishimura, Rachel | Urbanski, Maud | Venkatesan, Hariharan | Wang, Aihua | ... | Cummings, Maxwell D.
Patent Number: 10555941 (2020)
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Small molecule inhibitors of the JAK family of kinases (patent)
Kreutter, Kevin D. | Leonard, Kristi | Rizzolio, Michele C. | Smith, Russell C. | Tichenor, Mark S. | Wang, Aihua
Patent Number: 10487083 (2019)
Cite | Source
Phenyl linked quinolinyl modulators of RORγt (patent)
Leonard, Kristi A. | Barbay, Kent | Edwards, James P. | Kreutter, Kevin D. | Kummer, David A. | Maharoof, Umar | Nishimura, Rachel | Urbanski, Maud | Venkatesan, Hariharan | Wang, Aihua | ... | Cummings, Maxwell D.
Patent Number: 10369146 (2019)
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Small molecule inhibitors of the JAK family of kinases (patent)
Koudriakova, Tatiana | Kreutter, Kevin D. | Leonard, Kristi | Rizzolio, Michele C. | Smith, Russell C. | Tichenor, Mark S. | Wang, Aihua
Patent Number: 10364246 (2019)
Cite | Source
Small molecule inhibitors of the JAK family of kinases (patent)
Koudriakova, Tatiana | Kreutter, Kevin D. | Leonard, Kristi | Rizzolio, Michele C. | Smith, Russell C. | Tichenor, Mark S. | Wang, Aihua
Patent Number: 10294226 (2019)
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Quinolinyl modulators of RORγt (patent)
Leonard, Kristi A. | Barbay, Kent | Edwards, James P. | Kreutter, Kevin D. | Kummer, David A. | Maharoof, Umar | Nishimura, Rachel | Urbanski, Maud | Venkatesan, Hariharan | Wang, Aihua | ... | Tanis, Virginia
Patent Number: 10201546 (2019)
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6-Substituted quinolines as RORγt inverse agonists (journal article)
Barbay, J. Kent | Cummings, Maxwell D. | Abad, Marta | Castro, Glenda | Kreutter, Kevin D. | Kummer, David A. | Maharoof, Umar | Milligan, Cynthia | Nishimura, Rachel | Pierce, Joan | ... | Leonard, Kristi
Bioorganic & Medicinal Chemistry Letters, volume 27, issue 23, pages 5277-5283 (2017).
10.1016/j.bmcl.2017.10.027
Cited by (23) | Cite | Source
Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt (journal article)
Kummer, David A. | Cummings, Maxwell D. | Abad, Marta | Barbay, Joseph | Castro, Glenda | Wolin, Ronald | Kreutter, Kevin D. | Maharoof, Umar | Milligan, Cynthia | Nishimura, Rachel | ... | Leonard, Kristi
Bioorganic & Medicinal Chemistry Letters, volume 27, issue 9, pages 2047-2057 (2017).
10.1016/j.bmcl.2017.02.044
Cited by (25) | Cite | Source
Quinolinyl modulators of RORγt (patent)
Leonard, Kristi A. | Barbay, Kent | Edwards, James P. | Kreutter, Kevin D. | Kummer, David A. | Maharoof, Umar | Nishimura, Rachel | Urbanski, Maud | Venkatesan, Hariharan | Wang, Aihua | ... | Tanis, Virginia
Patent Number: 9624225 (2017)
Cited by (3) | Cite | Source
Phenyl linked quinolinyl modulators of RORγt (patent)
Leonard, Kristi A. | Barbay, Kent | Edwards, James P. | Kreutter, Kevin D. | Kummer, David A. | Maharoof, Umar | Nishimura, Rachel | Urbanski, Maud | Venkatesan, Hariharan | Wang, Aihua | ... | Cummings, Maxwell D.
Patent Number: 9403816 (2016)
Cited by (4) | Cite | Source
Alkyl linked quinolinyl modulators of RORγt (patent)
Leonard, Kristi A. | Barbay, Kent | Edwards, James P. | Kreutter, Kevin D. | Kummer, David A. | Maharoof, Umar | Nishimura, Rachel | Urbanski, Maud | Venkatesan, Hariharan | Wang, Aihua | ... | Cummings, Maxwell D.
Patent Number: 9346782 (2016)
Cited by (3) | Cite | Source
Heteroaryl linked quinolinyl modulators of RORgammat (patent)
Leonard, Kristi A. | Barbay, Kent | Edwards, James P. | Kreutter, Kevin D. | Kummer, David A. | Maharoof, Umar | Nishimura, Rachel | Urbanski, Maud | Venkatesan, Hariharan | Wang, Aihua | ... | Cummings, Maxwell D.
Patent Number: 9328095 (2016)
Cited by (3) | Cite | Source