Jeffery G. Saven

ScholarGPS® ID: 14165902687236

Affiliation
University of Pennsylvania, Philadelphia, United States
Affiliation History

Field
Physical Sciences and Mathematics
Discipline
Chemistry
Top Specialties
Peptide | Chemical Physics | Opioid | Physical Chemistry | Energy | Opioid Receptor | Polymer | Protein Engineering | Membrane Protein | Protein Folding | Structure Function | Bioinformatics | Biosensor | Biotechnology
Metrics Summary
Publication Count
131
Predicted Citations
8,433
Predicted h-index
55
Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

  • Publications
  • Books
  • Patents
  • NIH/NSF
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Impact of Peptide Length and Solution Conditions on Tetrameric Coiled Coil Formation (journal article)
Meisenhelter, Joshua E. | Petrich, Nolan R. | Blum, Jacquelyn E. | Weisen, Albree R. | Guo, Rui | Saven, Jeffery G. | Pochan, Darrin J. | Kloxin, Christopher J.
Biomacromolecules, volume 25, issue 6, pages 3775-3783 (2024).
10.1021/acs.biomac.4c00355
Cite | Source
Genetically Fused Resilin-like Polypeptide–Coiled Coil Bundlemer Conjugates Exhibit Tunable Multistimuli-Responsiveness and Undergo Nanofibrillar Assembly (journal article)
Patkar, Sai S. | Tang, Yao | Zhang, Tianren | Bisram, Arriana M. | Saven, Jeffery G. | Pochan, Darrin J. | Kiick, Kristi L.
Biomacromolecules, volume 25, issue 4, pages 2449-2461 (2024).
10.1021/acs.biomac.3c01402
Cite | Source
Thermoresponsive Coiled-Coil Peptide–Polymer Grafts (journal article)
Halaszynski, Nicole I. | Saven, Jeffery G. | Pochan, Darrin J. | Kloxin, Christopher J.
Bioconjugate Chemistry, volume 34, issue 11, pages 2001-2006 (2023).
10.1021/acs.bioconjchem.3c00367
Cite | Source
Genetic Fusion of Thermoresponsive Polypeptides with UCST‐type Behavior Mediates 1D Assembly of Coiled‐Coil Bundlemers (journal article)
Patkar, Sai S. | Tang, Yao | Bisram, Arriana M. | Zhang, Tianren | Saven, Jeffery G. | Pochan, Darrin J. | Kiick, Kristi L.
Angewandte Chemie International Edition, volume 62, issue 25 (2023).
10.1002/anie.202301331
Cited by (5) | Cite | Source
Genetic Fusion of Thermoresponsive Polypeptides with UCST‐type Behavior Mediates 1D Assembly of Coiled‐Coil Bundlemers (journal article)
Patkar, Sai S. | Tang, Yao | Bisram, Arriana M. | Zhang, Tianren | Saven, Jeffery G. | Pochan, Darrin J. | Kiick, Kristi L.
Angewandte Chemie, volume 135, issue 25 (2023).
10.1002/ange.202301331
Cited by (1) | Cite | Source
Computational Design of Homotetrameric Peptide Bundle Variants Spanning a Wide Range of Charge States (journal article)
Guo, Rui | Sinha, Nairiti J. | Misra, Rajkumar | Tang, Yao | Langenstein, Matthew | Kim, Kyunghee | Fagan, Jeffrey A. | Kloxin, Christopher J. | Jensen, Grethe | Pochan, Darrin J. | Saven, Jeffery G.
Biomacromolecules, volume 23, issue 4, pages 1652-1661 (2022).
10.1021/acs.biomac.1c01539
Cited by (6) | Cite | Source
Computational Design of Single-Peptide Nanocages with Nanoparticle Templating (journal article)
Villegas, José A. | Sinha, Nairiti J. | Teramoto, Naozumi | Von Bargen, Christopher D. | Pochan, Darrin J. | Saven, Jeffery G.
Molecules, volume 27, issue 4, pages 1237- (2022).
10.3390/molecules27041237
Cited by (6) | Cite | Source
Colloid-like solution behavior of computationally designed coiled coil bundlemers (journal article)
Sinha, Nairiti J. | Guo, Rui | Misra, Rajkumar | Fagan, Jeffrey | Faraone, Antonio | Kloxin, Christopher J. | Saven, Jeffery G. | Jensen, Grethe V. | Pochan, Darrin J.
Journal of Colloid and Interface Science, volume 606 (2022).
10.1016/j.jcis.2021.09.184
Cited by (4) | Cite | Source
Design of a Superpositively Charged Enzyme: Human Carbonic Anhydrase II Variant with Ferritin Encapsulation and Immobilization (journal article)
Bulos, Joshua A. | Guo, Rui | Wang, Zhiheng | DeLessio, Maegan A. | Saven, Jeffery G. | Dmochowski, Ivan J.
Biochemistry, volume 60, issue 47, pages 3596-3609 (2021).
10.1021/acs.biochem.1c00515
Cited by (9) | Cite | Source
Peptide Design and Self-assembly into Targeted Nanostructure and Functional Materials (journal article)
Sinha, Nairiti J. | Langenstein, Matthew G. | Pochan, Darrin J. | Kloxin, Christopher J. | Saven, Jeffery G.
Chemical Reviews, volume 121, issue 22, pages 13915-13935 (2021).
10.1021/acs.chemrev.1c00712
Cited by (131) | Cite | Source
Novel variants of engineered water soluble mu opioid receptors with extensive mutations and removal of cysteines (journal article)
Xi, Jin | Yang, Nanmu | Perez‐Aguilar, Jose Manuel | Selling, Bernard | Grothusen, John R. | Lamichhane, Rajan | Saven, Jeffery G. | Liu, Renyu
Proteins: Structure, Function, and Bioinformatics, volume 89, issue 10, pages 1386-1393 (2021).
10.1002/prot.26160
Cited by (1) | Cite | Source
Intramolecular structure and dynamics in computationally designed peptide-based polymers displaying tunable chain stiffness (journal article)
Sinha, Nairiti J. | Shi, Yi | Tang, Yao | Kloxin, Christopher J. | Saven, Jeffery G. | Faraone, Antonio | Jensen, Grethe V. | Pochan, Darrin J.
Physical Review Materials, volume 5, issue 9 (2021).
10.1103/PhysRevMaterials.5.095601
Cited by (2) | Cite | Source
Nanofibers Produced by Electrospinning of Ultrarigid Polymer Rods Made from Designed Peptide Bundlemers (journal article)
Kim, Kyunghee | Kloxin, Christopher J. | Saven, Jeffery G. | Pochan, Darrin J.
ACS Applied Materials & Interfaces, volume 13, issue 22, pages 26339-26351 (2021).
10.1021/acsami.1c04027
Cited by (14) | Cite | Source
Recombinant expression of computationally designed peptide-bundlemers in Escherichia coli (journal article)
Sinha, Nairiti J. | Kloxin, Christopher J. | Saven, Jeffery G. | Jensen, Grethe V. | Kelman, Zvi | Pochan, Darrin J.
Journal of Biotechnology, volume 330 (2021).
10.1016/j.jbiotec.2021.03.004
Cited by (6) | Cite | Source
The C-Terminus of the mu Opioid Receptor Is Critical in G-Protein Interaction as Demonstrated by a Novel Graphene Biosensor (journal article)
Wen, Chengyu | Selling, Bernard | Yeliseev, Alexei | Xi, Jin | Perez-Aguilar, Jose Manuel | Gao, Zhaoli | Saven, Jeffery G. | Johnson, A. T. Charlie | Liu, Renyu
IEEE Sensors Journal, volume 21, issue 5, pages 5758-5762 (2021).
10.1109/JSEN.2020.3043149
Cite | Source
Opioid detection based on high quality graphene transistor arrays and a synthetic mu receptor (patent)
Johnson, Alan T. | Xi, Jin | Han, Ganghee | Lerner, Mitchell | Saven, Jeffery G. | Liu, Renyu | Matsunaga, Felipe | Perez-Aguilar, Jose Manuel
Patent Number: 10809222 (2020)
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Characterization of an engineered water-soluble variant of the full-length human mu opioid receptor (journal article)
Xi, Jin | Xiao, Jie | Perez-Aguilar, Jose Manuel | Ping, Jinglei | Johnson, A.T. Charlie | Saven, Jeffery G. | Liu, Renyu
Journal of Biomolecular Structure and Dynamics, volume 38, issue 14, pages 4364-4370 (2020).
10.1080/07391102.2019.1677502
Cited by (1) | Cite | Source
Polyelectrolyte character of rigid rod peptide bundlemer chains constructed via hierarchical self-assembly (journal article)
Sinha, Nairiti J. | Wu, Dongdong | Kloxin, Christopher J. | Saven, Jeffery G. | Jensen, Grethe V. | Pochan, Darrin J.
Soft Matter, volume 15, issue 48, pages 9858-9870 (2019).
10.1039/C9SM01894H
Cited by (15) | Cite | Source
Polymers with controlled assembly and rigidity made with click-functional peptide bundles (journal article)
Wu, Dongdong | Sinha, Nairiti | Lee, Jeeyoung | Sutherland, Bryan P. | Halaszynski, Nicole I. | Tian, Yu | Caplan, Jeffrey | Zhang, Huixi Violet | Saven, Jeffery G. | Kloxin, Christopher J. | Pochan, Darrin J.
Nature, volume 574, issue 7780, pages 658-662 (2019).
10.1038/s41586-019-1683-4
Cited by (86) | Cite | Source
Fabrication of One- and Two-Dimensional Gold Nanoparticle Arrays on Computationally Designed Self-Assembled Peptide Templates (journal article)
Tian, Yu | Zhang, Huixi Violet | Kiick, Kristi L. | Saven, Jeffery G. | Pochan, Darrin J.
Chemistry of Materials, volume 30, issue 23, pages 8510-8520 (2018).
10.1021/acs.chemmater.8b03206
Cited by (20) | Cite | Source