Kongkai Zhu

ScholarGPS® ID: 13765762825496

Affiliation

University of Jinan, Jinan, China

Affiliation History

Field

Life Sciences

Discipline

Biology and Biological Sciences

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

2,125

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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First total synthesis, antitumor evaluation and target identification of mornaphthoate E: A new tubulin inhibitor template acting on PI3K/Akt signaling pathway (journal article) Shan, Peipei \| Ye, Tao \| Tang, Ying-De \| Song, Hui \| Wang, Chao \| Zhu, Kongkai \| Yang, Feifei \| Zhang, Shi-Lei \| Su, Pei-Wen \| Gao, Shuanhu \| Zhang, Hua Acta Pharmaceutica Sinica B, volume 14, issue 5, pages 2177-2193 (2024). 10.1016/j.apsb.2024.02.012 Cited by (3) \| Cite \| Source
Synthesis and biological evaluation of 1-phenyl-tetrahydro-β-carboline-based first dual PRMT5/EGFR inhibitors as potential anticancer agents (journal article) Zhang, Juan \| Liu, Xuliang \| Sa, Na \| Zhang, Jin-He \| Cai, Yong-Si \| Wang, Kai-Ming \| Xu, Wei \| Jiang, Cheng-Shi \| Zhu, Kong-Kai European Journal of Medicinal Chemistry, volume 269 (2024). 10.1016/j.ejmech.2024.116341 Cited by (2) \| Cite \| Source
Bioassay-guided discovery and identification of new potent α-glucosidase inhibitors from Morus alba L. and the interaction mechanism (journal article) Tian, Lin-Lin \| Bi, Yan-Xue \| Wang, Chao \| Zhu, Kongkai \| Xu, De-Feng \| Zhang, Hua Journal of Ethnopharmacology, volume 322 (2024). 10.1016/j.jep.2023.117645 Cited by (4) \| Cite \| Source
Discovery of tetrahydroisoquinolineindole derivatives as first dual PRMT5 inhibitors/hnRNP E1 upregulators: Design, synthesis and biological evaluation (journal article) Chu, Wen-Hui \| Yang, Na \| Zhang, Jin-He \| Li, Yue \| Song, Jia-Li \| Deng, Zhi-Peng \| Meng, Ning \| Zhang, Juan \| Zhu, Kong-Kai \| Jiang, Cheng-Shi European Journal of Medicinal Chemistry, volume 258 (2023). 10.1016/j.ejmech.2023.115625 Cited by (4) \| Cite \| Source
New monoterpenoid indole alkaloids from the stems of Tabernaemontana bovina Lour (Apocynaceae) (journal article) Yan, Xue-Wei \| Du, Si-Yu \| Wang, Xiao-Tong \| Zhu, Kong-Kai \| Fang, Lei Natural Product Research (2023). 10.1080/14786419.2023.2180503 Cite \| Source
Arginine Methyltransferase 5 (PRMT5) Inhibitors with 3-(1H-benzo[d]imidazol- 2-yl)anilines Core Identified by Virtual Screening and Biological Evaluation (journal article) Zhang, Ying \| Zhu, Kongkai \| Zhang, Juan \| Zhang, Jin-He \| Song, Zhiling \| Zhang, Xinlei \| Liu, Shan-Kui \| Jiang, Cheng-Shi Current Pharmaceutical Design, volume 29, issue 6, pages 474-479 (2023). 10.2174/1381612829666230215105046 Cited by (1) \| Cite \| Source
New aspidosperma-type alkaloids from Tabernaemontana bovina (journal article) Zhao, Xue \| Du, Si-Yu \| Liu, Jie \| Liu, Jia-Ning \| Jiang, Cheng-Shi \| Zhu, Kong-Kai \| Fang, Lei Phytochemistry Letters, volume 49 (2022). 10.1016/j.phytol.2022.03.016 Cited by (2) \| Cite \| Source
An overview of the development of EED inhibitors to disable the PRC2 function (journal article) Liu, Kai-Lu \| Zhu, Kongkai \| Zhang, Hua RSC Medicinal Chemistry, volume 13, issue 1, pages 39-53 (2022). 10.1039/D1MD00274K Cited by (11) \| Cite \| Source
GKK1032B from endophytic Penicillium citrinum induces the apoptosis of human osteosarcoma MG63 cells through caspase pathway activation (journal article) LIU, Na \| Song, Mei-Na \| Zhang, Qian-Qian \| WU, Cong \| ZHU, Kong-Kai \| SUN, Yu-Lin \| LI, Meng-Ru \| Yang, Feng-Ying \| Feng, Run-Liang \| Zhang, Yu-Ying \| Zhang, Hua Chinese Journal of Natural Medicines, volume 20, issue 1, pages 67-73 (2022). 10.1016/S1875-5364(21)60108-5 Cited by (2) \| Cite \| Source
Discovery of new 2-phenyl-1H-benzo[d]imidazole core-based potent α-glucosidase inhibitors: Synthesis, kinetic study, molecular docking, and in vivo anti-hyperglycemic evaluation (journal article) Li, Yue \| Zhang, Jin-He \| Xie, Hong-Xu \| Ge, Yong-Xi \| Wang, Kai-Ming \| Song, Zhi-Ling \| Zhu, Kong-Kai \| Zhang, Juan \| Jiang, Cheng-Shi Bioorganic Chemistry, volume 117 (2021). 10.1016/j.bioorg.2021.105423 Cited by (13) \| Cite \| Source
Design, synthesis and biological evaluation of novel (E)-2-benzylidene-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)hydrazine-1-carboxamide derivatives as α-glucosidase inhibitors (journal article) Zhang, Jin-He \| Xie, Hong-Xu \| Li, Yue \| Wang, Kai-Ming \| Song, Zhiling \| Zhu, Kong-Kai \| Fang, Lei \| Zhang, Juan \| Jiang, Cheng-Shi Bioorganic & Medicinal Chemistry Letters, volume 52 (2021). 10.1016/j.bmcl.2021.128413 Cited by (9) \| Cite \| Source
Diterpenoid glucosides with cystathionine γ-lyase inhibitory activity from Tinospora sinensis (journal article) Zhang, Jun-Sheng \| Hu, Youtian \| Song, Kun-Sheng \| Wu, Fang \| Zhu, Kongkai \| Xu, De-Feng \| Zhang, Hua Bioorganic Chemistry, volume 116 (2021). 10.1016/j.bioorg.2021.105400 Cited by (9) \| Cite \| Source
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel α-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation (journal article) Xie, Hong-Xu \| Zhang, Juan \| Li, Yue \| Zhang, Jin-He \| Liu, Shan-Kui \| Zhang, Jie \| Zheng, Hua \| Hao, Gui-Zhou \| Zhu, Kong-Kai \| Jiang, Cheng-Shi Bioorganic Chemistry, volume 115 (2021). 10.1016/j.bioorg.2021.105236 Cited by (21) \| Cite \| Source
Discovery of 3-(1H-indol-5-yl)-1,2,4-oxidizable derivatives as non-competitive α-glucosidase inhibitors (journal article) Zhang, Juan \| Ge, Yong-Xi \| Fang, Lei \| Zhu, Kong-Kai \| Liu, Shan-Kui \| Wang, Kai-Ming \| Jiang, Cheng-Shi Chemical Papers, volume 75, issue 9, pages 4661-4667 (2021). 10.1007/s11696-021-01687-8 Cited by (2) \| Cite \| Source
Single-molecule FRET and conformational analysis of beta-arrestin-1 through genetic code expansion and a Se-click reaction (journal article) Han, Ming-Jie \| He, Qing-tao \| Yang, Mengyi \| Chen, Chao \| Yao, Yirong \| Liu, Xiaohong \| Wang, Yuchuan \| Zhu, Zhong-liang \| Zhu, Kong-kai \| Qu, Changxiu \| ... \| Wang, Jiangyun Chemical Science, volume 12, issue 26, pages 9114-9123 (2021). 10.1039/D1SC02653D Cited by (10) \| Cite \| Source
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2–EED Interaction (journal article) Du, Daohai \| Xu, Dandan \| Zhu, Licheng \| Stazi, Giulia \| Zwergel, Clemens \| Liu, Yanli \| Luo, Zhongyuan \| Li, Yuanqing \| Zhang, Yuanyuan \| Zhu, Kongkai \| ... \| Luo, Cheng Journal of Medicinal Chemistry, volume 64, issue 12, pages 8194-8207 (2021). 10.1021/acs.jmedchem.0c02261 Cited by (26) \| Cite \| Source
New monoterpenoid indole alkaloids from Tabernaemontana bovina (journal article) Zhang, Miao \| Du, Si-Yu \| Liu, Jie \| Zhao, Xue \| Liu, Jia-Ning \| Jiang, Cheng-Shi \| Zhu, Kong-Kai \| Fang, Lei Phytochemistry Letters, volume 43 (2021). 10.1016/j.phytol.2021.03.006 Cited by (8) \| Cite \| Source
Discovery of New α-Glucosidase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation (journal article) Liu, Shan-Kui \| Hao, Haifang \| Bian, Yuan \| Ge, Yong-Xi \| Lu, Shengyuan \| Xie, Hong-Xu \| Wang, Kai-Ming \| Tao, Hongrui \| Yuan, Chao \| Zhang, Juan \| ... \| Zhu, Kongkai Frontiers in Chemistry, volume 9 (2021). 10.3389/fchem.2021.639279 Cited by (32) \| Cite \| Source
Nosiheptide analogues as potential antibacterial agents via dehydroalanine region modifications: Semi-synthesis, antimicrobial activity and molecular docking study (journal article) Fan, Yafei \| Chen, Hangfei \| Mu, Ning \| Wang, Wengui \| Zhu, Kongkai \| Ruan, Zhi \| Wang, Shoufeng Bioorganic & Medicinal Chemistry, volume 31 (2021). 10.1016/j.bmc.2020.115970 Cited by (7) \| Cite \| Source
Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers (journal article) Qin, Jing \| Qu, Sifeng \| Zhu, Kongkai \| Cheng, Yahong \| Pan, Ge \| Jing, Weiqiang \| Liu, Xigong \| Sun, Xia \| Liu, Lei Bioorganic & Medicinal Chemistry, volume 32 (2021). 10.1016/j.bmc.2021.116003 Cited by (5) \| Cite \| Source