Patricia C. Edwards

ScholarGPS® ID: 11583421053364

Affiliation

MRC Laboratory of Molecular Biology, United Kingdom

Affiliation History

Field

Life Sciences

Discipline

Molecular and Cell Biology

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

15,006

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Heterogeneous deposition of regular and mentholated little cigar smoke in the lungs of Sprague-Dawley rats (journal article) Lin, Kaisen \| Wallis, Christopher \| Wong, Emily M. \| Edwards, Patricia \| Cole, Austin \| Van Winkle, Laura \| Wexler, Anthony S. Particle and Fibre Toxicology, volume 20, issue 1 (2023). 10.1186/s12989-023-00554-6 Cite \| Source
Early-life ozone exposure modulates region-specific gene expression in the developing rat lung (journal article) Stevens, Nathanial C. \| Edwards, Patricia C. \| Van Winkle, Laura S. Toxicology Letters, volume 389 (2023). 10.1016/j.toxlet.2023.10.010 Cite \| Source
Alteration of glycosphingolipid metabolism by ozone is associated with exacerbation of allergic asthma characteristics in mice (journal article) Stevens, Nathanial C \| Brown, Veneese J \| Domanico, Morgan C \| Edwards, Patricia C \| Van Winkle, Laura S \| Fiehn, Oliver Toxicological Sciences, volume 191, issue 1, pages 79-89 (2023). 10.1093/toxsci/kfac117 Cited by (4) \| Cite \| Source
Aflatoxin B1 exposure disrupts the intestinal immune function via a soluble epoxide hydrolase-mediated manner (journal article) Wang, Weicang \| Wang, Yuxin \| Yang, Jun \| Wagner, Karen M. \| Hwang, Sung Hee \| Cheng, Jeff \| Singh, Nalin \| Edwards, Patricia \| Morisseau, Christophe \| Zhang, Guodong \| ... \| Hammock, Bruce D. Ecotoxicology and Environmental Safety, volume 249 (2023). 10.1016/j.ecoenv.2022.114417 Cited by (2) \| Cite \| Source
Cytotoxicity of 2D engineered nanomaterials in pulmonary and corneal epithelium (journal article) Domanico, Morgan \| Fukuto, Atsuhiko \| Tran, Lisa M. \| Bustamante, Jessica-Miranda \| Edwards, Patricia C. \| Pinkerton, Kent E. \| Thomasy, Sara M. \| Van Winkle, Laura S. NanoImpact, volume 26 (2022). 10.1016/j.impact.2022.100404 Cited by (6) \| Cite \| Source
Metabolomics of Lung Microdissections Reveals Region- and Sex-Specific Metabolic Effects of Acute Naphthalene Exposure in Mice (journal article) Stevens, Nathanial C \| Edwards, Patricia C \| Tran, Lisa M \| Ding, Xinxin \| Van Winkle, Laura S \| Fiehn, Oliver Toxicological Sciences, volume 184, issue 2, pages 214-222 (2021). 10.1093/toxsci/kfab110 Cited by (6) \| Cite \| Source
Differences in SMA-like polymer architecture dictate the conformational changes exhibited by the membrane protein rhodopsin encapsulated in lipid nano-particles (journal article) Grime, Rachael L. \| Logan, Richard T. \| Nestorow, Stephanie A. \| Sridhar, Pooja \| Edwards, Patricia C. \| Tate, Christopher G. \| Klumperman, Bert \| Dafforn, Tim R. \| Poyner, David R. \| Reeves, Philip J. \| Wheatley, Mark Nanoscale, volume 13, issue 31, pages 13519-13528 (2021). 10.1039/D1NR02419A Cited by (10) \| Cite \| Source
High-mass MALDI-MS unravels ligand-mediated G protein–coupling selectivity to GPCRs (journal article) Wu, Na \| Olechwier, Agnieszka M. \| Brunner, Cyrill \| Edwards, Patricia C. \| Tsai, Ching-Ju \| Tate, Christopher G. \| Schertler, Gebhard F. X. \| Schneider, Gisbert \| Deupi, Xavier \| Zenobi, Renato \| Ma, Pikyee Proceedings of the National Academy of Sciences, volume 118, issue 31 (2021). 10.1073/pnas.2024146118 Cited by (10) \| Cite \| Source
Comparison of acute respiratory epithelial toxicity for 4-Methylimidazole and naphthalene administered by oral gavage in B6C3F1 mice (journal article) Kelty, Jacklyn S. \| Keum, Chayoung \| Brown, Veneese J. \| Edwards, Patricia C. \| Carratt, Sarah A. \| Van Winkle, Laura S. Regulatory Toxicology and Pharmacology, volume 116 (2020). 10.1016/j.yrtph.2020.104761 Cited by (3) \| Cite \| Source
Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor (journal article) Lee, Yang \| Warne, Tony \| Nehmé, Rony \| Pandey, Shubhi \| Dwivedi-Agnihotri, Hemlata \| Chaturvedi, Madhu \| Edwards, Patricia C. \| García-Nafría, Javier \| Leslie, Andrew G. W. \| Shukla, Arun K. \| Tate, Christopher G. Nature, volume 583, issue 7818, pages 862-866 (2020). 10.1038/s41586-020-2419-1 Cited by (162) \| Cite \| Source
Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization (journal article) Pamula, Filip \| Mühle, Jonas \| Blanc, Alain \| Nehmé, Rony \| Edwards, Patricia C. \| Tate, Christopher G. \| Tsai, Ching-Ju Journal of Visualized Experiments (2020). 10.3791/60747 Cited by (1) \| Cite \| Source
Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization (journal article) Pamula, Filip \| Mühle, Jonas \| Blanc, Alain \| Nehmé, Rony \| Edwards, Patricia C. \| Tate, Christopher G. \| Tsai, Ching-Ju Journal of Visualized Experiments (2020). 10.3791/60747-v Cite \| Source
CryoEM at 100 keV: a demonstration and prospects (journal article) Naydenova, K. \| McMullan, G. \| Peet, M. J. \| Lee, Y. \| Edwards, P. C. \| Chen, S. \| Leahy, E. \| Scotcher, S. \| Henderson, R. \| Russo, C. J. IUCrJ, volume 6, issue 6, pages 1086-1098 (2019). 10.1107/S2052252519012612 Cited by (83) \| Cite \| Source
Age-Dependent Translocation of Gold Nanoparticles across the Air–Blood Barrier (journal article) Tsuda, Akira \| Donaghey, Thomas C. \| Konduru, Nagarjun V. \| Pyrgiotakis, Georgios \| Van Winkle, Laura S. \| Zhang, Zhenyuan \| Edwards, Patricia \| Bustamante, Jessica-Miranda \| Brain, Joseph D. \| Demokritou, Phillip ACS Nano, volume 13, issue 9, pages 10095-10102 (2019). 10.1021/acsnano.9b03019 Cited by (31) \| Cite \| Source
Molecular basis for high-affinity agonist binding in GPCRs (journal article) Warne, Tony \| Edwards, Patricia C. \| Doré, Andrew S. \| Leslie, Andrew G. W. \| Tate, Christopher G. Science, volume 364, issue 6442, pages 775-778 (2019). 10.1126/science.aau5595 Cited by (77) \| Cite \| Source
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST SALBUTAMOL AND NANOBODY Nb6B9 (journal article) Warne, Tony \| Edwards, Patricia C. \| Doré, Andrew S. \| Leslie, Andrew G. W. \| Tate, Christopher G. bioRxiv (2018). 10.2210/pdb6h7m/pdb Cite \| Source
Crystal structure of rhodopsin in complex with a mini-Go sheds light on the principles of G protein selectivity (journal article) Tsai, Ching-Ju \| Pamula, Filip \| Pamula, Filip \| Nehmé, Rony \| Mühle, Jonas \| Weinert, Tobias \| Flock, Tilman \| Flock, Tilman \| Flock, Tilman \| Nogly, Przemyslaw \| ... \| Schertler, Gebhard F. X. Science Advances, volume 4, issue 9 (2018). 10.2210/pdb6fuf/pdb Cite \| Source
Crystal structure of rhodopsin in complex with a mini-Go sheds light on the principles of G protein selectivity (journal article) Tsai, Ching-Ju \| Pamula, Filip \| Nehmé, Rony \| Mühle, Jonas \| Weinert, Tobias \| Flock, Tilman \| Nogly, Przemyslaw \| Edwards, Patricia C. \| Carpenter, Byron \| Gruhl, Thomas \| ... \| Schertler, Gebhard F. X. Science Advances, volume 4, issue 9 (2018). 10.1126/sciadv.aat7052 Cited by (53) \| Cite \| Source \| Open Access
Cryo-EM structure of the serotonin 5-HT1Breceptor coupled to heterotrimeric Go. (journal article) García-Nafría, Javier \| Nehmé, Rony \| Edwards, Patricia C. \| Tate, Christopher G. Nature, volume 558, issue 7711, pages 620-623 (2018). 10.2210/pdb6g79/pdb Cited by (7) \| Cite \| Source
Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go (journal article) García-Nafría, Javier \| Nehmé, Rony \| Edwards, Patricia C. \| Tate, Christopher G. Nature, volume 558, issue 7711, pages 620-623 (2018). 10.1038/s41586-018-0241-9 Cited by (166) \| Cite \| Source