Isabel Figueroa

ScholarGPS® ID: 10792816518805

Affiliation

AbbVie Inc., Lake Bluff, United States

Affiliation History

Field

Medicine

Discipline

Oncology

Top Specialties

Antibody | Antibody-drug Conjugate

Metrics Summary

Publication Count

Predicted Citations

253

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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Anti–Lymphocyte Antigen 6 Complex, Locus E- Seco -Cyclopropabenzindol-4-One-Dimer Antibody-Drug Conjugate That Forms Adduct with α 1-Microglobulin Demonstrates Slower Systemic Antibody Clearance and Reduced Tumor Distribution in Animals (journal article) Yip, Victor \| Figueroa, Isabel \| Latifi, Brandon \| Masih, Shab \| Ng, Carl \| Leipold, Doug \| Kamath, Amrita \| Shen, Ben-Quan Drug Metabolism and Disposition, volume 48, issue 12, pages 1247-1256 (2020). 10.1124/dmd.120.000145 Cite \| Source
Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy (journal article) Tom, Irene \| Pham, Victoria C. \| Katschke, Kenneth J. \| Li, Wei \| Liang, Wei-Ching \| Gutierrez, Johnny \| Ah Young, Andrew \| Figueroa, Isabel \| Eshghi, Shadi Toghi \| Lee, ChingWei V. \| ... \| Lill, Jennie R. Proceedings of the National Academy of Sciences, volume 117, issue 18, pages 9952-9963 (2020). 10.1073/pnas.1917608117 Cited by (36) \| Cite \| Source
Antibody-drug conjugates: integrated bioanalytical and biodisposition assessments in lead optimization and selection (journal article) Beaumont, Maribel \| Tomazela, Daniela \| Hodges, Douglas \| Ermakov, Grigori \| Hsieh, Edward \| Figueroa, Isabel \| So, On-Yee \| Song, Yaoli \| Ma, Huiping \| Antonenko, Svetlana \| ... \| Escandón, Enrique AAPS Open, volume 4, issue 1 (2018). 10.1186/s41120-018-0026-0 Cited by (5) \| Cite \| Source \| Open Access
Preclinical pharmacokinetics and pharmacodynamics of DCLL9718A: An antibody-drug conjugate for the treatment of acute myeloid leukemia (journal article) Leipold, Douglas D. \| Figueroa, Isabel \| Masih, Shabkhaiz \| Latifi, Brandon \| Yip, Victor \| Shen, Ben-Quan \| Dere, Randall C. \| Carrasco-Triguero, Montserrat \| Lee, M. Violet \| Saad, Ola M. \| ... \| Kamath, Amrita V. mAbs, volume 10, issue 8, pages 1312-1321 (2018). 10.1080/19420862.2018.1517565 Cited by (13) \| Cite \| Source
Site-specific conjugation allows modulation of click reaction stoichiometry for pretargeted SPECT imaging (journal article) Mandikian, Danielle \| Rafidi, Hanine \| Adhikari, Pragya \| Venkatraman, Priya \| Nazarova, Lidia \| Fung, Gabriel \| Figueroa, Isabel \| Ferl, Gregory Z. \| Ulufatu, Sheila \| Ho, Jason \| ... \| Boswell, C. Andrew mAbs, volume 10, issue 8, pages 1269-1280 (2018). 10.1080/19420862.2018.1521132 Cited by (8) \| Cite \| Source
Tissue Physiology of Cynomolgus Monkeys: Cross-Species Comparison and Implications for Translational Pharmacology (journal article) Mandikian, Danielle \| Figueroa, Isabel \| Oldendorp, Amy \| Rafidi, Hanine \| Ulufatu, Sheila \| Schweiger, Michelle G. \| Couch, Jessica A. \| Dybdal, Noel \| Joseph, Sean B. \| Prabhu, Saileta \| ... \| Boswell, C. Andrew The AAPS Journal, volume 20, issue 6 (2018). 10.1208/s12248-018-0264-z Cited by (19) \| Cite \| Source
Prediction of non-linear pharmacokinetics in humans of an antibody-drug conjugate (ADC) when evaluation of higher doses in animals is limited by tolerability: Case study with an anti-CD33 ADC (journal article) Figueroa, Isabel \| Leipold, Doug \| Leong, Steve \| Zheng, Bing \| Triguero-Carrasco, Montserrat \| Fourie-O'Donohue, Aimee \| Kozak, Katherine R. \| Xu, Keyang \| Schutten, Melissa \| Wang, Hong \| ... \| Kamath, Amrita V. mAbs, volume 10, issue 5, pages 738-750 (2018). 10.1080/19420862.2018.1465160 Cited by (3) \| Cite \| Source \| Open Access
Stimulus-Response Mechanisms: An Overview (book chapter) In Development of Antibody-Based Therapeutics Tabrizi, Mohammad A. \| Sadekar, Shraddha S. \| Figueroa, Isabel \| Ovacik, Ayse M. Springer Singapore (2018) 10.1007/978-981-13-0496-5_7 Cite \| Source
Evaluation of Tumor Growth Inhibition in Preclinical Tumor Models: A Quantitative Approach (book chapter) In Development of Antibody-Based Therapeutics Sadekar, Shraddha \| Figueroa, Isabel \| Shankaran, Harish Springer Singapore (2018) 10.1007/978-981-13-0496-5_8 Cite \| Source
Antibody Drug Conjugates: Translational Considerations (book chapter) In Development of Antibody-Based Therapeutics Tabrizi, Mohammad A. \| Figueroa, Isabel \| Blumenschein, Wendy \| Grein, Jeff Springer Singapore (2018) 10.1007/978-981-13-0496-5_10 Cite \| Source
Discovery of Pyrophosphate Diesters as Tunable, Soluble, and Bioorthogonal Linkers for Site-Specific Antibody–Drug Conjugates (journal article) Kern, Jeffrey C. \| Cancilla, Mark \| Dooney, Deborah \| Kwasnjuk, Kristen \| Zhang, Rena \| Beaumont, Maribel \| Figueroa, Isabel \| Hsieh, SuChun \| Liang, Linda \| Tomazela, Daniela \| ... \| Garbaccio, Robert M. Journal of the American Chemical Society, volume 138, issue 4, pages 1430-1445 (2016). 10.1021/jacs.5b12547 Cited by (105) \| Cite \| Source