Rémy Gébleux

ScholarGPS® ID: 10387050765566

Affiliation

NBE-Therapeutics AG

Affiliation History

Field

Life Sciences

Discipline

Biology and Biological Sciences

Top Specialties

Antibody | Antibody-drug Conjugate

Metrics Summary

Publication Count

Predicted Citations

655

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

Add Delete
NBE-002: A novel anthracycline-based antibody-drug conjugate (ADC) targeting ROR1 for the treatment of advanced solid tumors—A phase 1/2 clinical trial. (journal article) Tolcher, Anthony W. \| Meric-Bernstam, Funda \| McKean, Meredith \| Beerli, Roger R \| Waldmeier, Lorenz \| Gebleux, Rémy \| Hellmann, Ina \| Chrom, Pawel \| Grawunder, Ulf Journal of Clinical Oncology, volume 39, issue 15_suppl, pages TPS1108-TPS1108 (2021). 10.1200/JCO.2021.39.15_suppl.TPS1108 Cited by (9) \| Cite \| Source
Anthracycline-based antibody drug conjugates having high in vivo tolerability (patent) Grawunder, Ulf \| Beerli, Roger \| Gebleux, Remy Patent Number: 10758556 (2020) Cite \| Source
A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer (journal article) D’Amico, Lucia \| Menzel, Ulrike \| Prummer, Michael \| Müller, Philipp \| Buchi, Mélanie \| Kashyap, Abhishek \| Haessler, Ulrike \| Yermanos, Alexander \| Gébleux, Rémy \| Briendl, Manfred \| ... \| Zippelius, Alfred Journal for ImmunoTherapy of Cancer, volume 7, issue 1 (2019). 10.1186/s40425-018-0464-1 Cited by (72) \| Cite \| Source
Characterization of the housekeeping sortase from the human pathogen Propionibacterium acnes : first investigation of a class F sortase (journal article) Di Girolamo, Salvatore \| Puorger, Chasper \| Castiglione, Mara \| Vogel, Maren \| Gébleux, Rémy \| Briendl, Manfred \| Hell, Tamara \| Beerli, Roger R. \| Grawunder, Ulf \| Lipps, Georg Biochemical Journal, volume 476, issue 4, pages 665-682 (2019). 10.1042/BCJ20180885 Cited by (10) \| Cite \| Source
Sortase A Enzyme-Mediated Generation of Site-Specifically Conjugated Antibody–Drug Conjugates (book chapter) In Enzyme-Mediated Ligation Methods Gébleux, Rémy \| Briendl, Manfred \| Grawunder, Ulf \| Beerli, Roger R. Springer New York (2019) 10.1007/978-1-4939-9546-2_1 Cited by (9) \| Cite \| Source
Cost-effective large-scale expression of proteins for NMR studies (journal article) Klopp, Julia \| Winterhalter, Aurélie \| Gébleux, Rémy \| Scherer-Becker, Daniela \| Ostermeier, Christian \| Gossert, Alvar D. Journal of Biomolecular NMR, volume 71, issue 4, pages 247-262 (2018). 10.1007/s10858-018-0179-0 Cited by (11) \| Cite \| Source
A non-internalizing antibody-drug conjugate based on an anthracycline payload displays potent therapeutic activity in vivo (journal article) Dal Corso, Alberto \| Gébleux, Rémy \| Murer, Patrizia \| Soltermann, Alex \| Neri, Dario Journal of Controlled Release, volume 264 (2017). 10.1016/j.jconrel.2017.08.040 Cited by (60) \| Cite \| Source
Protease-Cleavable Linkers Modulate the Anticancer Activity of Noninternalizing Antibody–Drug Conjugates (journal article) Dal Corso, Alberto \| Cazzamalli, Samuele \| Gébleux, Rémy \| Mattarella, Martin \| Neri, Dario Bioconjugate Chemistry, volume 28, issue 7, pages 1826-1833 (2017). 10.1021/acs.bioconjchem.7b00304 Cited by (63) \| Cite \| Source
Highly Potent, Anthracycline-based Antibody–Drug Conjugates Generated by Enzymatic, Site-specific Conjugation (journal article) Stefan, Nikolas \| Gébleux, Rémy \| Waldmeier, Lorenz \| Hell, Tamara \| Escher, Marie \| Wolter, Fabian I. \| Grawunder, Ulf \| Beerli, Roger R. Molecular Cancer Therapeutics, volume 16, issue 5, pages 879-892 (2017). 10.1158/1535-7163.MCT-16-0688 Cited by (60) \| Cite \| Source \| Open Access
Non‐internalizing antibody–drug conjugates display potent anti‐cancer activity upon proteolytic release of monomethyl auristatin E in the subendothelial extracellular matrix (journal article) Gébleux, Rémy \| Stringhini, Marco \| Casanova, Ruben \| Soltermann, Alex \| Neri, Dario International Journal of Cancer, volume 140, issue 7, pages 1670-1679 (2017). 10.1002/ijc.30569 Cited by (90) \| Cite \| Source \| Open Access
Antibody-drug conjugates: Current status and future perspectives (journal article) Gébleux, Rémy \| Casi, Giulio Pharmacology & Therapeutics, volume 167 (2016). 10.1016/j.pharmthera.2016.07.012 Cited by (51) \| Cite \| Source
Antibody Format and Drug Release Rate Determine the Therapeutic Activity of Noninternalizing Antibody–Drug Conjugates (journal article) Gébleux, Rémy \| Wulhfard, Sarah \| Casi, Giulio \| Neri, Dario Molecular Cancer Therapeutics, volume 14, issue 11, pages 2606-2612 (2015). 10.1158/1535-7163.MCT-15-0480 Cited by (54) \| Cite \| Source \| Open Access