Bruce H. Horwitz

ScholarGPS® ID: 10061165220104

Affiliation

Boston Children's Hospital, Boston, United States

Affiliation History

Field

Medicine

Discipline

Emergency Medicine

Top Specialties

Metrics Summary

Publication Count

Predicted Citations

5,980

Predicted h-index

Ranking

Publications and Citation History

Publications based on Top Specialties

Types of Publication

Publications
Books
Patents
NIH/NSF

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BREASTFEEDING STATUS AND DISEASE SEVERITY IN PEDIATRIC PATIENTS WITH ULCERATIVE COLITIS: AN EXPLORATORY RETROSPECTIVE COHORT STUDY (journal article) Glick, Abigail \| Horwitz, Bruce \| Snapper, Scott \| Ouahed, Jodie Inflammatory Bowel Diseases, volume 30, issue Supplement_1, pages S66-S67 (2024). 10.1093/ibd/izae020.143 Cite \| Source
BACTERIAL SPHINGOLIPIDS EXACERBATE COLITIS BY INHIBITING ILC3-DERIVED IL-22 PRODUCTION (journal article) Bao, Bin \| Wang, Youyuan \| Boudreau, Pavl \| Song, Xinyang \| Wu, Meng \| Chen, Xi \| Patik, Izabel \| Tang, Ying \| Ouahed, Jodie \| Wu, Chuan \| ... \| Snapper, Scott Inflammatory Bowel Diseases, volume 30, issue Supplement_1, pages S63-S63 (2024). 10.1093/ibd/izae020.133 Cite \| Source
The IL-10 receptor inhibits cell extrinsic signals necessary for STAT1-dependent macrophage accumulation during colitis (journal article) Patik, Izabel \| Redhu, Naresh S. \| Eran, Alal \| Bao, Bin \| Nandy, Anubhab \| Tang, Ying \| El Sayed, Shorouk \| Shen, Zeli \| Glickman, Jonathan \| Fox, James G. \| ... \| Horwitz, Bruce H. Mucosal Immunology, volume 16, issue 3, pages 233-249 (2023). 10.1016/j.mucimm.2023.02.006 Cited by (3) \| Cite \| Source
Monocytes transition to macrophages within the inflamed vasculature via monocyte CCR2 and endothelial TNFR2 (journal article) Mysore, Vijayashree \| Tahir, Suhail \| Furuhashi, Kazuhiro \| Arora, Jatin \| Rosetti, Florencia \| Cullere, Xavier \| Yazbeck, Pascal \| Sekulic, Miroslav \| Lemieux, Madeleine E. \| Raychaudhuri, Soumya \| ... \| Mayadas, Tanya N. Journal of Experimental Medicine, volume 219, issue 5 (2022). 10.1084/jem.20210562 Cited by (32) \| Cite \| Source
Sa1532: INTRINSIC STAT1 SIGNALING IS REQUIRED FOR COLONIC MACROPHAGE ACCUMULATION IN IL10RA-DEFICIENT MICE (journal article) Patik, Izabel \| Redhu, Naresh S. \| Nandy, Anubhab \| Bao, Bin \| Tang, Ying \| Shen, Zeli \| Sayed, Shorouk El \| Glickman, Jonathan \| Fox, James G. \| Snapper, Scott B. \| Horwitz, Bruce Gastroenterology, volume 162, issue 7, pages S-404-S-405 (2022). 10.1016/S0016-5085(22)60959-4 Cite \| Source
Monocytes transition to monocyte‐macrophages within the inflamed vasculature via CCR2 on monocytes and endothelial TNFR2 (journal article) Sathyanarayana Mysore, Vijayashree \| Tahir, Suhail \| Furuhashi, Kazuhiro \| Arora, Jatin \| Rosetti, Florencia \| Cullere, Xavier \| Yazbeck, Pascal \| Sekulic, Miroslav \| Lemieux, Madeleine E. \| Raychaudhuri, Soumya \| ... \| Mayadas, Tanya The FASEB Journal, volume 36, issue S1 (2022). 10.1096/fasebj.2022.36.S1.R3229 Cited by (1) \| Cite \| Source
CCR2 promotes monocyte recruitment and intestinal inflammation in mice lacking the interleukin-10 receptor (journal article) El Sayed, Shorouk \| Patik, Izabel \| Redhu, Naresh S. \| Glickman, Jonathan N. \| Karagiannis, Konstantinos \| El Naenaeey, El Sayed Y. \| Elmowalid, Gamal A. \| Abd El Wahab, Ashraf M. \| Snapper, Scott B. \| Horwitz, Bruce H. Scientific Reports, volume 12, issue 1 (2022). 10.1038/s41598-021-04098-7 Cited by (11) \| Cite \| Source
Utilizing a reductionist model to study host-microbe interactions in intestinal inflammation (journal article) Tsou, Amy M. \| Goettel, Jeremy A. \| Bao, Bin \| Biswas, Amlan \| Kang, Yu Hui \| Redhu, Naresh S. \| Peng, Kaiyue \| Putzel, Gregory G. \| Saltzman, Jeffrey \| Kelly, Ryan \| ... \| Snapper, Scott B. Microbiome, volume 9, issue 1 (2021). 10.1186/s40168-021-01161-3 Cited by (9) \| Cite \| Source
Effects of Colonization of Gnotobiotic Swiss Webster Mice with Helicobacter bilis (journal article) Whary, Mark T \| Wang, Chuanwu \| Ruff, Catherine F \| DiVincenzo, Mallory J \| Labriola, Caralyn \| Ge, Lillian \| Feng, Yan \| Ge, Zhongming \| Bakthavatchalu, Vasu \| Muthupalani, Suresh \| ... \| Fox, James G Comparative Medicine, volume 70, issue 3, pages 216-232 (2020). 10.30802/AALAS-CM-19-000087 Cited by (5) \| Cite \| Source
399 PROTEOMIC AND TRANSCRIPTOMIC ANALYSIS OF VERY EARLY ONSET IBD MUCOSA ACROSS INTERNATIONAL SITES REVEALS PATIENTSPECIFIC INFLAMMATORY CELLULAR SIGNATURES (journal article) Mitsialis, Vanessa \| Ordovas-Montanes, Jose \| Field, Michael \| Wall, Sarah \| Patik, Izabel \| Warner, Neil E. \| Kotlarz, Daniel \| Fiedler, Karoline B. \| Green, Julia \| Whitcomb, Sydney \| ... \| Snapper, Scott B. Gastroenterology, volume 158, issue 6, pages S-73- (2020). 10.1016/S0016-5085(20)30865-9 Cite \| Source
Generation of protective pneumococcal-specific nasal resident memory CD4+ T cells via parenteral immunization (journal article) O'Hara, Joanne M. \| Redhu, Naresh S \| Cheung, Elaine \| Robertson, Nahid G. \| Patik, Izabel \| Sayed, Shorouk El \| Thompson, Claudette M. \| Herd, Muriel \| Lucas, Katherine B. \| Conaway, Evan \| ... \| Horwitz, Bruce H. Mucosal Immunology, volume 13, issue 1, pages 172-182 (2020). 10.1038/s41385-019-0218-5 Cited by (27) \| Cite \| Source
Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis (journal article) Ryzhakov, Grigory \| West, Nathaniel R. \| Franchini, Fanny \| Clare, Simon \| Ilott, Nicholas E. \| Sansom, Stephen N. \| Bullers, Samuel J. \| Pearson, Claire \| Costain, Alice \| Vaughan-Jackson, Alun \| ... \| Powrie, Fiona Nature Communications, volume 9, issue 1 (2018). 10.1038/s41467-018-06085-5 Cited by (40) \| Cite \| Source \| Open Access
WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis (journal article) Biswas, Amlan \| Shouval, Dror S. \| Griffith, Alexandra \| Goettel, Jeremy A. \| Field, Michael \| Kang, Yu Hui \| Konnikova, Liza \| Janssen, Erin \| Redhu, Naresh Singh \| Thrasher, Adrian J. \| ... \| Snapper, Scott B. Nature Communications, volume 9, issue 1 (2018). 10.1038/s41467-018-03670-6 Cited by (35) \| Cite \| Source \| Open Access
Interleukin-22 drives nitric oxide-dependent DNA damage and dysplasia in a murine model of colitis-associated cancer (journal article) Wang, C. \| Gong, G. \| Sheh, A. \| Muthupalani, S. \| Bryant, E.M. \| Puglisi, D.A. \| Holcombe, H. \| Conaway, E.A. \| Parry, N A P \| Bakthavatchalu, V. \| ... \| Horwitz, B.H. Mucosal Immunology, volume 10, issue 6, pages 1504-1517 (2017). 10.1038/mi.2017.9 Cited by (52) \| Cite \| Source \| Open Access
Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor (journal article) Redhu, Naresh S \| Bakthavatchalu, Vasudevan \| Conaway, Evan A \| Shouval, Dror S \| Tsou, Amy \| Goettel, Jeremy A \| Biswas, Amlan \| Wang, Chuanwu \| Field, Michael \| Muller, Werner \| ... \| Horwitz, Bruce H eLife, volume 6 (2017). 10.7554/eLife.27652 Cited by (26) \| Cite \| Source \| Open Access
Inhibition of Inflammatory Gene Transcription by IL-10 Is Associated with Rapid Suppression of Lipopolysaccharide-Induced Enhancer Activation (journal article) Conaway, Evan A. \| de Oliveira, Dalila C. \| McInnis, Christine M. \| Snapper, Scott B. \| Horwitz, Bruce H. The Journal of Immunology, volume 198, issue 7, pages 2906-2915 (2017). 10.4049/jimmunol.1601781 Cited by (30) \| Cite \| Source \| Open Access
Interleukin 1β Mediates Intestinal Inflammation in Mice and Patients With Interleukin 10 Receptor Deficiency (journal article) Shouval, Dror S. \| Biswas, Amlan \| Kang, Yu Hui \| Griffith, Alexandra E. \| Konnikova, Liza \| Mascanfroni, Ivan D. \| Redhu, Naresh S. \| Frei, Sandra M. \| Field, Michael \| Doty, Andria L. \| ... \| Snapper, Scott B. Gastroenterology, volume 151, issue 6, pages 1100-1104 (2016). 10.1053/j.gastro.2016.08.055 Cited by (140) \| Cite \| Source \| Open Access
O-005 YI Microbiota Drives Inflammation by Altering Intestinal Lamina Propria Macrophage Phenotype in a Novel IL10R-Deficient Model of Very Early Onset IBD (journal article) Redhu, Naresh \| Shouval, Dror \| Bakthavatchalu, Vasudevan \| Wang, Chuanwu \| Conaway, Evan \| Goettel, Jeremy \| Mack, Matthias \| Bleich, Andre \| Bry, Lynn \| Fox, James \| ... \| Horwitz, Bruce Inflammatory Bowel Diseases, volume 22 (2016). 10.1097/01.MIB.0000480043.65761.b2 Cited by (2) \| Cite \| Source \| Open Access
P-135 YI IL-22 Promotes Helicobacter Hepaticus-Induced H2AX Phosphorylation and Dysbiosis in the Large Bowel (journal article) Wang, Chuanwu \| Gong, Guanyu \| Sheh, Alexander \| Muthupalani, Sureshkumar \| Parry, Nicola \| Bakthavatchalu, Vasudevan \| Tannenbaum, Steven \| Fox, James \| Horwitz, Bruce Inflammatory Bowel Diseases, volume 22 (2016). 10.1097/01.MIB.0000480240.70523.91 Cite \| Source \| Open Access
Mo1773 IL-10R Signaling Restricts the Expansion of Microbiota-Driven Proinflammatory Macrophages in the Colon of Infant Mice (journal article) Redhu, Naresh S. \| Shouval, Dror S. \| Bry, Lynn \| Snapper, Scott B. \| Horwitz, Bruce Gastroenterology, volume 148, issue 4, pages S-708- (2015). 10.1016/S0016-5085(15)32403-3 Cite \| Source

Title	Investigators	Year	Cost	Agency
Inhibition of Microflora-Induced Colitis by NF-kB	Horwitz, Bruce H	2010	$440,400	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Inhibition of Microflora-Induced Colitis by NF-kB	Horwitz, Bruce H.	2009	$458,755	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Inhibition of Microflora-Induced Colitis by NF-kB	Horwitz, Bruce H	2007	$351,254	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Inhibition of Microflora-Induced Colitis by NF-kB	Horwitz, Bruce H	2006	$361,745	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PF # 3: Regulation of Cutaneous Inflammation by Inhibitory NF-kB Subunits (Bru	Horwitz, Bruce H	2006	$25,000	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Inhibition of Microflora-Induced Colitis by NF-kB	Horwitz, Bruce H	2005	$370,450	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
PF # 3: Regulation of Cutaneous Inflammation by Inhibitory NF-kB Subunits (Bru	Horwitz, Bruce H	2005	$25,000	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
PF # 3: Regulation of Cutaneous Inflammation by Inhibitory NF-kB Subunits (Bru	Horwitz, Bruce H	2004	$43,250	NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
Inhibition of Microflora-Induced Colitis by NF-kB	Horwitz, Bruce H	2004	$370,450	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Inhibition of Microflora-Induced Colitis by NF-kB	Horwitz, Bruce H	2003	$185,225	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES